메뉴 건너뛰기




Volumn 287, Issue 51, 2012, Pages 42856-42866

The zinc finger protein ZNF268 is overexpressed in human cervical cancer and contributes to tumorigenesis via enhancing NF-κB signaling

Author keywords

[No Author keywords available]

Indexed keywords

CELL-CYCLE ARREST; CERVICAL CANCER CELLS; CERVICAL CANCERS; COLONY FORMATION; HELA CELL; HIGH FREQUENCY; HUMAN PAPILLOMAVIRUS; IN-VITRO; INDUCED APOPTOSIS; ISOFORMS; NUDE MICE; OVER-EXPRESSION; TUMORIGENESIS; WOMEN'S HEALTH; ZINC FINGER PROTEIN;

EID: 84871145018     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.399923     Document Type: Article
Times cited : (30)

References (41)
  • 1
    • 0346274978 scopus 로고    scopus 로고
    • KRAB-containing zinc-finger repressor proteins
    • Urrutia, R. (2003) KRAB-containing zinc-finger repressor proteins. Genome Biol. 4, 231
    • (2003) Genome Biol. , vol.4 , pp. 231
    • Urrutia, R.1
  • 3
    • 33750581080 scopus 로고    scopus 로고
    • KRAB-containing zinc finger gene ZNF268 encodes multiple alternatively spliced isoforms that contain transcription regulatory domains
    • Shao, H., Zhu, C., Zhao, Z., Guo, M., Qiu, H., Liu, H., Wang, D., Xue, L., Gao, L., Sun, C., and Li, W. (2006) KRAB-containing zinc finger gene ZNF268 encodes multiple alternatively spliced isoforms that contain transcription regulatory domains. Int. J. Mol. Med. 18, 457-463
    • (2006) Int. J. Mol. Med. , vol.18 , pp. 457-463
    • Shao, H.1    Zhu, C.2    Zhao, Z.3    Guo, M.4    Qiu, H.5    Liu, H.6    Wang, D.7    Xue, L.8    Gao, L.9    Sun, C.10    Li, W.11
  • 6
    • 21644477508 scopus 로고    scopus 로고
    • ZNF268, a novel Kruppel-like zinc finger protein, is implicated in early human liver development
    • Sun, Y., Shao, H., Li, Z., Liu, J., Gao, L., Peng, X., Meng, Y., and Li, W. (2004) ZNF268, a novel Kruppel-like zinc finger protein, is implicated in early human liver development. Int. J. Mol. Med. 14, 971-975
    • (2004) Int. J. Mol. Med. , vol.14 , pp. 971-975
    • Sun, Y.1    Shao, H.2    Li, Z.3    Liu, J.4    Gao, L.5    Peng, X.6    Meng, Y.7    Li, W.8
  • 7
    • 0037105497 scopus 로고    scopus 로고
    • Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX
    • DOI 10.1182/blood-2002-02-0513
    • Krackhardt, A. M., Witzens, M., Harig, S., Hodi, F. S., Zauls, A. J., Chessia, M., Barrett, P., and Gribben, J. G. (2002) Identification of tumor-associated antigens in chronic lymphocytic leukemia by SEREX. Blood 100, 2123-2131 (Pubitemid 35001247)
    • (2002) Blood , vol.100 , Issue.6 , pp. 2123-2131
    • Krackhardt, A.M.1    Witzens, M.2    Harig, S.3    Stephen, H.F.4    Jason, Z.A.5    Chessia, M.6    Barrett, P.7    Gribben, J.G.8
  • 8
    • 47749135294 scopus 로고    scopus 로고
    • Human T-cell leukemia virus type 1 oncoprotein tax represses ZNF268 expression through the cAMP-responsive element-binding protein/activating transcription factor pathway
    • Wang, D., Guo, M. X., Hu, H. M., Zhao, Z. Z., Qiu, H. L., Shao, H. J., Zhu, C. G., Xue, L., Shi, Y. B., and Li, W. X. (2008) Human T-cell leukemia virus type 1 oncoprotein tax represses ZNF268 expression through the cAMP-responsive element-binding protein/activating transcription factor pathway. J. Biol. Chem. 283, 16299-16308
    • (2008) J. Biol. Chem. , vol.283 , pp. 16299-16308
    • Wang, D.1    Guo, M.X.2    Hu, H.M.3    Zhao, Z.Z.4    Qiu, H.L.5    Shao, H.J.6    Zhu, C.G.7    Xue, L.8    Shi, Y.B.9    Li, W.X.10
  • 9
    • 84855338007 scopus 로고    scopus 로고
    • Knockdown of ZNF268, which is transcriptionally down-regulated by GATA-1, promotes proliferation of K562 cells
    • Zeng, Y., Wang, W., Ma, J., Wang, X., Guo, M., and Li, W. (2012) Knockdown of ZNF268, which is transcriptionally down-regulated by GATA-1, promotes proliferation of K562 cells. PLoS ONE 7, e29518
    • (2012) PLoS ONE , vol.7
    • Zeng, Y.1    Wang, W.2    Ma, J.3    Wang, X.4    Guo, M.5    Li, W.6
  • 15
    • 0033596127 scopus 로고    scopus 로고
    • Control of apoptosis by Rel/NF-κB transcription factors
    • Barkett, M., and Gilmore, T. D. (1999) Control of apoptosis by Rel/NF-κB transcription factors. Oncogene 18, 6910-6924
    • (1999) Oncogene , vol.18 , pp. 6910-6924
    • Barkett, M.1    Gilmore, T.D.2
  • 16
    • 4444376712 scopus 로고    scopus 로고
    • Signaling to NF-κB
    • Hayden, M. S., and Ghosh, S. (2004) Signaling to NF-κB. Genes Dev. 18, 2195-2224
    • (2004) Genes Dev. , vol.18 , pp. 2195-2224
    • Hayden, M.S.1    Ghosh, S.2
  • 17
    • 0037204948 scopus 로고    scopus 로고
    • TNF-R1 signaling: A beautiful pathway
    • DOI 10.1126/science.1071924
    • Chen, G., and Goeddel, D. V. (2002) TNF-R1 signaling: a beautiful pathway. Science 296, 1634-1635 (Pubitemid 34579145)
    • (2002) Science , vol.296 , Issue.5573 , pp. 1634-1635
    • Chen, G.1    Goeddel, D.V.2
  • 18
    • 33745298519 scopus 로고    scopus 로고
    • Nuclear factor-κB in cancer development and progression
    • Karin, M. (2006) Nuclear factor-κB in cancer development and progression. Nature 441, 431-436
    • (2006) Nature , vol.441 , pp. 431-436
    • Karin, M.1
  • 19
    • 0037426670 scopus 로고    scopus 로고
    • NF-κB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix
    • DOI 10.1038/sj.onc.1206043
    • Nair, A., Venkatraman, M., Maliekal, T. T., Nair, B., and Karunagaran, D. (2003) NF-κB is constitutively activated in high-grade squamous intraepithelial lesions and squamous cell carcinomas of the human uterine cervix. Oncogene 22, 50-58 (Pubitemid 36152883)
    • (2003) Oncogene , vol.22 , Issue.1 , pp. 50-58
    • Nair, A.1    Venkatraman, M.2    Maliekal, T.T.3    Nair, B.4    Karunagaran, D.5
  • 20
    • 76249093944 scopus 로고    scopus 로고
    • Quantum-dot-based immunofluorescent imaging of HER2 and ER provides new insights into breast cancer heterogeneity
    • Chen, C., Peng, J., Xia, H., Wu, Q., Zeng, L., Xu, H., Tang, H., Zhang, Z., Zhu, X., Pang, D., and Li, Y. (2010) Quantum-dot-based immunofluorescent imaging of HER2 and ER provides new insights into breast cancer heterogeneity. Nanotechnology 21, 095101
    • (2010) Nanotechnology , vol.21 , pp. 095101
    • Chen, C.1    Peng, J.2    Xia, H.3    Wu, Q.4    Zeng, L.5    Xu, H.6    Tang, H.7    Zhang, Z.8    Zhu, X.9    Pang, D.10    Li, Y.11
  • 21
    • 0029849620 scopus 로고    scopus 로고
    • Cancer cell cycles
    • Sherr, C. J. (1996) Cancer cell cycles. Science 274, 1672-1677
    • (1996) Science , vol.274 , pp. 1672-1677
    • Sherr, C.J.1
  • 22
    • 0035927495 scopus 로고    scopus 로고
    • Cytokines in cervicovaginal washing fluid from patients with cervical neoplasia
    • DOI 10.1006/cyto.2001.0909
    • Tjiong, M. Y., van der Vange, N., ter Schegget, J. S., Burger, M. P., ten Kate, F. W., and Out, T. A. (2001) Cytokines in cervicovaginal washing fluid from patients with cervical neoplasia. Cytokine 14, 357-360 (Pubitemid 32730478)
    • (2001) Cytokine , vol.14 , Issue.6 , pp. 357-360
    • Tjiong, M.Y.1    Van Der, V.N.2    Ter, S.J.S.3    Burger, M.P.M.4    Ten, K.F.W.J.5    Out, T.A.6
  • 23
    • 0029884068 scopus 로고    scopus 로고
    • Tumor necrosis factor α interferes with the cell cycle of normal and papillomavirus-immortalized human keratinocytes
    • Vieira, K. B., Goldstein, D. J., and Villa, L. L. (1996) Tumor necrosis factor α interferes with the cell cycle of normal and papillomavirus- immortalized human keratinocytes. Cancer Res. 56, 2452-2457 (Pubitemid 26154098)
    • (1996) Cancer Research , vol.56 , Issue.10 , pp. 2452-2457
    • Vieira, K.B.L.1    Goldstein, D.J.2    Villa, L.L.3
  • 24
    • 39049183044 scopus 로고    scopus 로고
    • Regulation and function of IKK and IKK-related kinases
    • Häcker, H., and Karin, M. (2006) Regulation and function of IKK and IKK-related kinases. Sci. STKE 2006, re13
    • (2006) Sci. STKE , vol.2006
    • Häcker, H.1    Karin, M.2
  • 25
    • 2942650958 scopus 로고    scopus 로고
    • Hsp70 promotes TNF-mediated apoptosis by binding IKKγ and impairing NF-κB survival signaling
    • DOI 10.1101/gad.1188204
    • Ran, R., Lu, A., Zhang, L., Tang, Y., Zhu, H., Xu, H., Feng, Y., Han, C., Zhou, G., Rigby, A. C., and Sharp, F. R. (2004) Hsp70 promotes TNF-mediated apoptosis by binding IKKγ and impairing NF-κB survival signaling. Genes Dev. 18, 1466-1481 (Pubitemid 38780632)
    • (2004) Genes and Development , vol.18 , Issue.12 , pp. 1466-1481
    • Ran, R.1    Lu, A.2    Zhang3    Tang, Y.4    Zhu, H.5    Xu, H.6    Feng, Y.7    Han, C.8    Zhou, G.9    Rigby, A.C.10    Sharp, F.R.11
  • 26
    • 0036899102 scopus 로고    scopus 로고
    • KRAB zinc finger proteins: An analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution
    • Looman, C., Abrink, M., Mark, C., and Hellman, L. (2002) KRAB zinc finger proteins. An analysis of the molecular mechanisms governing their increase in numbers and complexity during evolution. Mol. Biol. Evol. 19, 2118-2130 (Pubitemid 35440448)
    • (2002) Molecular Biology and Evolution , vol.19 , Issue.12 , pp. 2118-2130
    • Looman, C.1    Abrink, M.2    Mark, C.3    Hellman, L.4
  • 27
    • 0037443035 scopus 로고    scopus 로고
    • Pre-mRNA splicing and human disease
    • DOI 10.1101/gad.1048803
    • Faustino, N. A., and Cooper, T. A. (2003) Pre-mRNA splicing and human disease. Genes Dev. 17, 419-437 (Pubitemid 36258756)
    • (2003) Genes and Development , vol.17 , Issue.4 , pp. 419-437
    • Faustino, N.A.1    Cooper, T.A.2
  • 28
    • 3042642783 scopus 로고    scopus 로고
    • Splice variants as cancer biomarkers
    • Brinkman, B. M. (2004) Splice variants as cancer biomarkers. Clin. Biochem. 37, 584-594
    • (2004) Clin. Biochem. , vol.37 , pp. 584-594
    • Brinkman, B.M.1
  • 30
    • 77951044009 scopus 로고    scopus 로고
    • Alternative splicing of human papillomavirus type-16 E6/E6*early mRNA is coupled to EGF signaling via Erk1/2 activation
    • Rosenberger, S., De-Castro Arce, J., Langbein, L., Steenbergen, R. D., and Rösl, F. (2010) Alternative splicing of human papillomavirus type-16 E6/E6*early mRNA is coupled to EGF signaling via Erk1/2 activation. Proc. Natl. Acad. Sci. U.S.A. 107, 7006-7011
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 7006-7011
    • Rosenberger, S.1    De-Castro Arce, J.2    Langbein, L.3    Steenbergen, R.D.4    Rösl, F.5
  • 31
    • 32244447214 scopus 로고    scopus 로고
    • Cytoplasmic/nuclear shuttling and tumor progression
    • Wang, S. C., and Hung, M. C. (2005) Cytoplasmic/nuclear shuttling and tumor progression. Ann. N.Y. Acad. Sci. 1059, 11-15
    • (2005) Ann. N.Y. Acad. Sci. , vol.1059 , pp. 11-15
    • Wang, S.C.1    Hung, M.C.2
  • 32
    • 0038809057 scopus 로고    scopus 로고
    • The KRAB domain of zinc finger gene ZNF268: A potential transcriptional repressor
    • DOI 10.1080/1521654031000110208
    • Sun, Y., Gou, D. M., Liu, H., Peng, X., and Li, W. X. (2003) The KRAB domain of zinc finger gene ZNF268: a potential transcriptional repressor. IUBMB Life 55, 127-131 (Pubitemid 36702656)
    • (2003) IUBMB Life , vol.55 , Issue.3 , pp. 127-131
    • Sun, Y.1    Gou, D.-M.2    Liu, H.3    Peng, X.4    Li, W.-X.5
  • 33
    • 33746637977 scopus 로고    scopus 로고
    • Upregulation of nuclear factor-κB (NF-κB) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus or disease outcome in cervical cancer
    • DOI 10.1002/dc.20514
    • Branca, M., Giorgi, C., Ciotti, M., Santini, D., Di Bonito, L., Costa, S., Benedetto, A., Bonifacio, D., Di Bonito, P., Paba, P., Accardi, L., Mariani, L., Ruutu, M., Syrjänen, S., Favalli, C., and Syrjänen, K. (2006) Up-regulation of nuclear factor-κB (NF-κB) is related to the grade of cervical intraepithelial neoplasia, but is not an independent predictor of high-risk human papillomavirus or disease outcome in cervical cancer. Diagn. Cytopathol. 34, 555-563 (Pubitemid 44157177)
    • (2006) Diagnostic Cytopathology , vol.34 , Issue.8 , pp. 555-563
    • Branca, M.1    Giorgi, C.2    Ciotti, M.3    Santini, D.4    Di, B.L.5    Costa, S.6    Benedetto, A.7    Bonifacio, D.8    Di, B.P.9    Paba, P.10    Accardi, L.11    Mariani, L.12    Ruutu, M.13    Syrjanen, S.14    Favalli, C.15    Syrjanen, K.16
  • 34
    • 33947202249 scopus 로고    scopus 로고
    • Nuclear factor-κB in development, prevention, and therapy of cancer
    • Van Waes, C. (2007) Nuclear factor-κB in development, prevention, and therapy of cancer. Clin. Cancer Res. 13, 1076-1082
    • (2007) Clin. Cancer Res. , vol.13 , pp. 1076-1082
    • Van Waes, C.1
  • 37
    • 0029033861 scopus 로고
    • The retinoblastoma protein and cell cycle control
    • Weinberg, R. A. (1995) The retinoblastoma protein and cell cycle control. Cell 81, 323-330
    • (1995) Cell , vol.81 , pp. 323-330
    • Weinberg, R.A.1
  • 39
    • 5444256371 scopus 로고    scopus 로고
    • Inflammation as a tumor promoter in cancer induction
    • DOI 10.1016/j.semcancer.2004.06.006, PII S1044579X04000495
    • Philip, M., Rowley, D. A., and Schreiber, H. (2004) Inflammation as a tumor promoter in cancer induction. Semin. Cancer Biol. 14, 433-439 (Pubitemid 39360991)
    • (2004) Seminars in Cancer Biology , vol.14 , Issue.6 , pp. 433-439
    • Philip, M.1    Rowley, D.A.2    Schreiber, H.3
  • 40
    • 0033568358 scopus 로고    scopus 로고
    • Essential role of tumor necrosis factor α (TNF-α) in tumor promotion as revealed by TNF-α-deficient mice
    • Suganuma, M., Okabe, S., Marino, M. W., Sakai, A., Sueoka, E., and Fujiki, H. (1999) Essential role of tumor necrosis factor α (TNF-α) in tumor promotion as revealed by TNF-α-deficient mice. Cancer Res. 59, 4516-4518 (Pubitemid 29428949)
    • (1999) Cancer Research , vol.59 , Issue.18 , pp. 4516-4518
    • Suganuma, M.1    Okabe, S.2    Marino, M.W.3    Sakai, A.4    Sueoka, E.5    Fujiki, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.