Liquid chromatography-mass spectrometry method for the analysis of 1,4-dimethylpyridinium in rat plasma - application to pharmacokinetic studies

Biomedical Chromatography

Volumn 27, Issue 1, 2013, Pages 73-79

  Szafarz, Malgorzata ^a,b   Szymura Oleksiak, Joanna ^a,b   Zakrzewska, Agnieszka ^b   Walczak, Maria ^a,b   Kus, Kamil ^a,b   Gonciarz, Anna ^a,b  

^a JAGIELLONIAN UNIVERSITY MEDICAL COLLEGE   (Poland)

^b JAGIELLONIAN UNIVERSITY   (Poland)

Author keywords

1,4 DMP compound; Column liquid chromatography; Rats plasma; Tandem MS detection

Indexed keywords

BODY FLUIDS; COLUMN CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; HIGH PRESSURE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS;

1,4-DIMETHYLPYRIDINIA COMPOUND; ANALYTICAL COLUMNS; COLUMN LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY - MASS SPECTROMETRIES; LIQUID CHROMATOGRAPHY-ELECTROSPRAY IONIZATION-MASS SPECTROMETRIES; MS DETECTION; PHARMACOKINETIC STUDIES; RAT PLASMA; TANDEM MS; TANDEM MS DETECTION;

RATS;

1,4 DIMETHYLPYRIDINIUM; ACETONITRILE; FORMIC ACID; PYRIDINIUM DERIVATIVE; UNCLASSIFIED DRUG; WATER;

ACCURACY; ANALYTIC METHOD; ARTICLE; CALIBRATION; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG CLEARANCE; DRUG DETERMINATION; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STABILITY; ELECTROSPRAY MASS SPECTROMETRY; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PHARMACOKINETICS; PILOT STUDY; RAT;

RATTUS;

EID: 84871107447     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.2750     Document Type: Article

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