Changes in the diagnosed incidence of early onset schizophrenia over four decades

Acta Psychiatrica Scandinavica

Volumn 127, Issue 1, 2012, Pages 62-68

  Okkels, N ^a   Vernal, D L ^b   Jensen, S O W ^a   Mcgrath, J J ^c,d   Nielsen, R E ^a,e  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

^b Aalborg Psykiatriske Sygehus   (Denmark)

^c QUEENSLAND CENTRE FOR MENTAL HEALTH RESEARCH   (Australia)

^d UNIVERSITY OF QUEENSLAND   (Australia)

^e Regional Psychiatric Services West   (Denmark)

Author keywords

Epidemiology; Incidence; Schizophrenia

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CHILD; DISEASE REGISTRY; EARLY ONSET SCHIZOPHRENIA; FEMALE; HUMAN; INCIDENCE; INFANT; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHIZOPHRENIA; SCHOOL CHILD; SEX DIFFERENCE; STANDARDIZATION;

EID: 84871078699     PISSN: 0001690X     EISSN: 16000447     Source Type: Journal    
DOI: 10.1111/j.1600-0447.2012.01913.x     Document Type: Article

References (42)

1. Hafner H, Maurer K, Loffler W, Riecher-Rossler A. The influence of age and sex on the onset and early course of schizophrenia. Br J Psychiatry 1993;162:80-86.
2. Thorup A, Waltoft BL, Pedersen CB, Mortensen PB, Nordentoft M. Young males have a higher risk of developing schizophrenia: a Danish register study. Psychol Med 2007;37:479-484.
3. Stenstrom AD, Christiansen E, Dehlholm-Lambertsen B, Nohr-Jensen P, Bilenberg N. [Rising incidence rates of schizophrenia among children and adolescents]. Ugeskr Laeger 2010;172:2131-2135.
4. Thomsen PH. Schizophrenia with childhood and adolescent onset--a nationwide register-based study. Acta Psychiatr Scand 1996;94:187-193.
5. Kyriakopoulos M, Frangou S. Pathophysiology of early onset schizophrenia. Int Rev Psychiatry 2007;19:315-324.
6. Alvarez-Jimenez M, Parker AG, Hetrick SE, Mcgorry PD, Gleeson JF. Preventing the second episode: a systematic review and meta-analysis of psychosocial and pharmacological trials in first-episode psychosis. Schizophr Bull 2011;37:619-630.
7. Anderson KK, Fuhrer R, Malla AK. The pathways to mental health care of first-episode psychosis patients: a systematic review. Psychol Med 2010;40:1585-1597.
8. Bertelsen M, Jeppesen P, Petersen L et al.Five-year follow-up of a randomized multicenter trial of intensive early intervention vs standard treatment for patients with a first episode of psychotic illness: the OPUS trial. Arch Gen Psychiatry 2008;65:762-771.
9. Amminger GP, Henry LP, Harrigan SM et al.Outcome in early-onset schizophrenia revisited: findings from the Early Psychosis Prevention and Intervention Centre long-term follow-up study. Schizophr Res 2011;131:112-119.
10. Codony M, Alonso J, Almansa J et al.Perceived need for mental health care and service use among adults in Western Europe: results of the ESEMeD project. Psychiatr Serv 2009;60:1051-1058.
11. Tiainen A, Edman G, Flyckt L, Tomson G, Rehnberg C. Regional variations and determinants of direct psychiatric costs in Sweden. Scand J Public Health 2008;36:483-492.
12. Mcgrath JJ. Myths and plain truths about schizophrenia epidemiology--the NAPE lecture 2004. Acta Psychiatr Scand 2005;111:4-11.
13. Eaton WW, Mortensen PB, Frydenberg M. Obstetric factors, urbanization and psychosis. Schizophr Res 2000;43:117-123.
14. Messias EL, Chen CY, Eaton WW. Epidemiology of schizophrenia: review of findings and myths. Psychiatr Clin North Am 2007;30:323-338.
15. Tsuchiya KJ, Munk-Jorgensen P. First-admission rates of schizophrenia in Denmark, 1980-1997: have they been increasing?Schizophr Res 2002;54:187-191.
16. Munk-Jorgensen P. Why has the incidence of schizophrenia in Danish psychiatric institutions decreased since 1970?Acta Psychiatr Scand 1987;75:62-68.
17. Munk-Jorgensen P, Mortensen PB. Is schizophrenia really on the decrease?Eur Arch Psychiatry Clin Neurosci 1993;242:244-247.
18. Munk-Jorgensen P. Decreasing first-admission rates of schizophrenia among males in Denmark from 1970 to 1984. Changing diagnostic patterns?. Acta Psychiatr Scand 1986;73:645-650.
19. Bogren M, Mattisson C, Isberg PE, Munk-Jorgensen P, Nettelbladt P. Incidence of psychotic disorders in the 50year follow up of the Lundby population. Aust N Z J Psychiatry 2010;44:31-39.
20. Boydell J, Van OS J, Lambri M et al.Incidence of schizophrenia in south-east London between 1965 and 1997. Br J Psychiatry 2003;182:45-49.
21. Mcgrath J, Saha S, Welham J, El Saadi O, Maccauley C, Chant D. A systematic review of the incidence of schizophrenia: the distribution of rates and the influence of sex, urbanicity, migrant status and methodology. BMC Med 2004;2:13.
22. Salokangas RK, Helminen M, Koivisto AM et al.Incidence of hospitalised schizophrenia in Finland since 1980: decreasing and increasing again. Soc Psychiatry Psychiatr Epidemiol 2011;46:343-350.
23. Der G, Gupta S, Murray RM. Is schizophrenia disappearing?Lancet 1990;335:513-516.
24. Mors O, Perto GP, Mortensen PB. The Danish Psychiatric Central Research Register. Scand J Public Health 2011;39:54-57.
25. Munk-Jorgensen P, Ostergaard SD. Register-based studies of mental disorders. Scand J Public Health 2011;39:170-174.
26. Lauritsen MB, Jorgensen M, Madsen KM et al.Validity of childhood autism in the Danish Psychiatric Central Register: findings from a cohort sample born 1990-1999. J Autism Dev Disord 2010;40:139-148.
27. Ahmad OB, Boschi-Pinto C, Lopez AD, Murray CJL, Lozano R, Inoue M. Age standardization of rates: A new WHO standard. GPE Discussion Paper Series 2001;No. 31.
28. Clayton D, Hills M. Statistical models in epidemiology. Oxford: Oxford University Press, 1993.
29. STATACORP LP. Stata Statistical Software. College Station, TX: STATACORP LP, 2009; Release 11.
30. Ajdacic-Gross V, Lauber C, Warnke I, Haker H, Murray RM, Rossler W. Changing incidence of psychotic disorders among the young in Zurich. Schizophr Res 2007;95:9-18.
31. Loffler W, Hafner H, Fatkenheuer B et al.Validation of Danish case register diagnosis for schizophrenia. Acta Psychiatr Scand 1994;90:196-203.
32. Velthortst E, Nieman DH, Klaassen RM et al.Three-year course of clinical symptomatology in young people at ultra high risk for transition to psychosis. Acta Psychiatr Scand 2011;123:36-42.
33. Nielsen J, Le QP, Emborg C, Foldager L, Correll CU. 10-Year trends in the treatment and outcomes of patients with first-episode schizophrenia. Acta Psychiatr Scand 2010;122:356-366.
34. Hjortso S, Butler B, Clemmesen L et al.The use of case vignettes in studies of interrater reliability of psychiatric target syndromes and diagnoses. A comparison of ICD-8, ICD-10 and DSM-III. Acta Psychiatr Scand 1989;80:632-638.
35. Aleman A, Kahn RS, Selten JP. Sex differences in the risk of schizophrenia: evidence from meta-analysis. Arch Gen Psychiatry 2003;60:565-571.
36. Van OS J. 'Salience syndrome' replaces 'schizophrenia' in DSM-V and ICD-11: psychiatry's evidence-based entry into the 21st century?Acta Psychiatr Scand 2009;120:363-372.
37. Arendt M, Rosenberg R, Foldager L, Perto G, Munk-Jorgensen P. Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases. Br J Psychiatry 2005;187:510-515.
38. Arseneault L, Cannon M, Witton J, Murray RM. Causal association between cannabis and psychosis: examination of the evidence. Br J Psychiatry 2004;184:110-117.
39. Henquet C, Murray R, Linszen D, Van OJ. The environment and schizophrenia: the role of cannabis use. Schizophr Bull 2005;31:608-612.
40. Machielsen M, Van Der Sluis S, De Haan L. Cannabis use in patients with a first psychotic episode and subjects at ultra high risk of psychosis: impact on psychotic- and pre-psychotic symptoms. Aust N Z J Psychiatry 2010;44:721-728.
41. Von SK, Lieb R, Pfister H, Hofler M, Wittchen HU. Use, abuse and dependence of ecstasy and related drugs in adolescents and young adults-a transient phenomenon? Results from a longitudinal community study. Drug Alcohol Depend 2002;66:147-159.
42. Veen ND, Selten JP, Van DTI, Feller WG, Hoek HW, Kahn RS. Cannabis use and age at onset of schizophrenia. Am J Psychiatry 2004;161:501-506.