UK investments in global infectious disease research 1997-2010: A case study

The Lancet Infectious Diseases

Volumn 13, Issue 1, 2013, Pages 55-64

  Head, Michael G ^a   Fitchett, Joseph R ^b   Cooke, Mary K ^a   Wurie, Fatima B ^a   Hayward, Andrew C ^a   Atun, Rifat ^c  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT;

AFRICAN TRYPANOSOMIASIS; ANTIBIOTIC RESISTANCE; ANTIFUNGAL RESISTANCE; ANTIVIRAL RESISTANCE; ARTICLE; ASPERGILLOSIS; BLOODSTREAM INFECTION; BRAIN INFECTION; CAMPYLOBACTERIOSIS; CANDIDIASIS; CHAGAS DISEASE; CHICKENPOX; CHLAMYDIA; CLOSTRIDIUM INFECTION; CYTOMEGALOVIRUS INFECTION; DATA BASE; DENGUE; DIPHTHERIA; DISABILITY ADJUSTED LIFE YEARS; DISEASE BURDEN; DISEASE MANAGEMENT; EPSTEIN BARR VIRUS INFECTION; ESCHERICHIA COLI INFECTION; EYE INFECTION; FILARIASIS; FUNDING; GASTROINTESTINAL INFECTION; GENERAL ASPECTS OF DISEASE; GONORRHEA; HEALTH CARE ORGANIZATION; HELICOBACTER INFECTION; HELMINTHIASIS; HEPATITIS; HEPATITIS C; HERPES SIMPLEX; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION; INFLUENZA; LEISHMANIASIS; LEPROSY; LISTERIOSIS; MALARIA; MEASLES; MEDICAL RESEARCH; MENINGITIS; MORTALITY; NOROVIRUS INFECTION; PAPILLOMAVIRUS INFECTION; PERTUSSIS; POLIOMYELITIS; PRIORITY JOURNAL; PSEUDOMONAS INFECTION; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RESPIRATORY TRACT INFECTION; ROTAVIRUS INFECTION; SALMONELLOSIS; SCHISTOSOMIASIS; SEXUALLY TRANSMITTED DISEASE; SHIGELLOSIS; SYPHILIS; SYSTEMATIC REVIEW; TETANUS; TRACHOMA; TROPICAL DISEASE; TUBERCULOSIS; UNITED KINGDOM; VIROLOGY;

BIOMEDICAL RESEARCH; CASE-CONTROL STUDIES; COMMUNICABLE DISEASES; DATABASES, FACTUAL; GREAT BRITAIN; HUMANS; REGRESSION ANALYSIS; RESOURCE ALLOCATION;

EID: 84871052731     PISSN: 14733099     EISSN: 14744457     Source Type: Journal    
DOI: 10.1016/S1473-3099(12)70261-X     Document Type: Article

References (29)

1. The global burden of disease: 2004 update 2008, WHO, World Health Organization, Geneva.
2. Fisk NM, McKee M, Atun R Relative and absolute addressability of global disease burden in maternal and perinatal health by investment in R&D. Trop Med Int Health 2011, 16:662-668.
3. Fisk NM, Atun R Market failure and the poverty of new drugs in maternal health. PLoS Med 2008, 5:e22.
4. Fisk NM, Atun R Systematic analysis of research underfunding in maternal and perinatal health. BJOG 2009, 116:347-356.
5. Global Report for Research on Infectious Diseases of Poverty 2012, World Health Organization on behalf of the Special Programme for Research and Training in Tropical Diseases 2012, WHO Document Production Services, Geneva.
6. Moran M, Guzman J, Henderson K, et al. Neglected disease research and development: is the global financial crisis changing R&D? 2010, Policy Cures, Sydney.
7. Moran M, Guzman J, Abela-Oversteegen L, et al. Neglected disease research and development: is innovation under threat? 2011, Policy Cures, Sydney.
8. Gross CP, Anderson GF, Powe NR The relation between funding by the National Institutes of Health and the burden of disease. N Engl J Med 1999, 340:1881-1887.
9. Catalá López F, Alvarez Martín E, Gènova Maleras R, Morant Ginestar C Relationship between research funding in the Spanish National Health System and the burden of disease. Rev Esp Salud Publica 2009, 83:137-151.
10. Mitchell RJ, McClure RJ, Olivier J, Watson WL. Rational allocation of Australia's research dollars: does the distribution of NHMRC funding by National Health Priority Area reflect actual disease burden? Med J Aust; 191: 648-52.
11. Lamarre-Cliche M, Castilloux AM, LeLorier J Association between the burden of disease and research funding by the Medical Research Council of Canada and the National Institutes of Health. A cross-sectional study. Clin Invest Med 2001, 24:83-89.
12. UK health research analysis 2009, UKCRC Strategic Planning Group on Microbiology and Infectious Diseases Research, UK Clinical Research Collaboration, London.
13. Metrics: disability-adjusted life year (DALY). Quantifying the Burden of Disease from mortality and morbidity WHO, (accessed Aug 6, 2012). http://www.who.int/healthinfo/global_burden_disease/metrics_daly/en/.
14. Wernli D, Haustein T, Conly J, Carmeli Y, Kickbusch I, Harbarth S A call for action: the application of The International Health Regulations to the global threat of antimicrobial resistance. PLoS Med 2011, 8:e1001022.
15. Chan ED, Iseman MD Multidrug-resistant and extensively drug-resistant tuberculosis: a review. Curr Opin Infect Dis 2008, 21:587-595.
16. Elliott SR, Beeson JG Estimating the burden of global mortality in children aged <5 years by pathogen-specific causes. Clin Infect Dis 2008, 46:1794-1795.
17. Kau AL, Ahern PP, Griffin NW, Goodman AL, Gordon JI Human nutrition, the gut microbiome and the immune system. Nature 2011, 474:327-336.
18. Mandalia S, Mandalia R, Lo G, et al. Rising population cost for treating people living with HIV in the UK, 1997-2013. PLoS One 2010, 5:e15677.
19. Liese BH, Schubert L Official development assistance for health-how neglected are neglected tropical diseases? An analysis of health financing. Int Health 2009, 1:141-147.
20. Following the money: toward better tracking of global health resources 2007, Global Health Resource Tracking Working Group, Center for Global Development, Washington DC.
21. McCoy D, Chand S, Sridhar D Global health funding: how much, where it comes from and where it goes. Health Policy Plan 2009, 24:407-417.
22. Terry RF, van der Rijt T Overview of research activities associated with the World Health Organization: results of a survey covering 2006/07. Health Res Policy Syst 2010, 8:25.
23. Lopez A Health and health-research priorities: has WHO got it right?. Lancet 2008, 372:1525-1527.
24. Stuckler D, King L, Robinson H, McKee M WHO's budgetary allocations and burden of disease: a comparative analysis. Lancet 2008, 372:1563-1569.
25. Payne L, Fitchett JR Bringing neglected tropical diseases into the spotlight. Trends Parasitol 2010, 26:421-423.
26. Morris K Time to overcome the neglect of neglected tropical diseases. Lancet Infect Dis 2010, 10:820-821.
27. Progress and challenges in neglected tropical diseases. Lancet 2010, 376:1363. The Lancet.
28. Zachariah R, Ford N, Maher D, et al. Is operational research delivering the goods? The journey to success in low-income countries. Lancet Infect Dis 2012, 12:415-421.
29. Hotez PJ, Molyneux DH, Fenwick A, Ottesen E, Ehrlich Sachs S, Sachs JD Incorporating a rapid-impact package for neglected tropical diseases with programs for HIV/AIDS, tuberculosis, and malaria. PLoS Med 2006, 3:e102.