메뉴 건너뛰기




Volumn 61, Issue 11, 2012, Pages 2113-2123

Antitumoral activity of parvovirus-mediated IL-2 and MCP-3/CCL7 delivery into human pancreatic cancer: Implication of leucocyte recruitment

Author keywords

Chemokine; IL 2; Pancreatic carcinoma; Parvovirus

Indexed keywords

GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 2; MONOCYTE CHEMOTACTIC PROTEIN 3; PARVOVIRUS VECTOR;

EID: 84871025600     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-012-1279-4     Document Type: Article
Times cited : (43)

References (49)
  • 1
    • 1642312315 scopus 로고    scopus 로고
    • Genetic alterations in pancreatic carcinoma
    • Schneider G, Schmid RM (2003) Genetic alterations in pancreatic carcinoma. Mol Cancer 2:15
    • (2003) Mol Cancer , vol.2 , pp. 15
    • Schneider, G.1    Schmid, R.M.2
  • 2
    • 0037314610 scopus 로고    scopus 로고
    • A phase i/ii trial of intratumoral endoscopic ultrasound injection of onyx-015 with intravenous gemcitabine in unresectable pancreatic carcinoma
    • Hecht JR, Bedford R, Abbruzzese JL, Lahoti S, Reid TR, Soetikno RM, Kirn DH, Freeman SM (2003) A phase I/II trial of intratumoral endoscopic ultrasound injection of ONYX-015 with intravenous gemcitabine in unresectable pancreatic carcinoma. Clin Cancer Res 9(2):555-561
    • (2003) Clin Cancer Res , vol.9 , Issue.2 , pp. 555-561
    • Hecht, J.R.1    Bedford, R.2    Abbruzzese, J.L.3    Lahoti, S.4    Reid, T.R.5    Soetikno, R.M.6    Kirn, D.H.7    Freeman, S.M.8
  • 3
    • 33646468422 scopus 로고    scopus 로고
    • Development of the panvacvf vaccine for pancreatic cancer
    • doi 101586/14760584519
    • Petrulio CA, Kaufman HL (2006) Development of the PANVACVF vaccine for pancreatic cancer. Exp Rev Vac 5(1):9-19. doi: 10.1586/14760584.5.1.9
    • (2006) Exp Rev Vac , vol.5 , Issue.1 , pp. 9-19
    • Petrulio, C.A.1    Kaufman, H.L.2
  • 4
    • 34447276472 scopus 로고    scopus 로고
    • Le morte du tumour: Histological features of tumor destruction in chemo-resistant cancers following intravenous infusions of pathotropic nanoparticles bearing therapeutic genes
    • Gordon EM, Chan MT, Geraldino N, Lopez FF, Cornelio GH, Lorenzo CC 3rd, Levy JP, Reed RA, Liu L, Hall FL (2007) Le morte du tumour: histological features of tumor destruction in chemo-resistant cancers following intravenous infusions of pathotropic nanoparticles bearing therapeutic genes. Int J Oncol 30(6):1297-1307
    • (2007) Int J Oncol , vol.30 , Issue.6 , pp. 1297-1307
    • Gordon, E.M.1    Chan, M.T.2    Geraldino, N.3    Lopez, F.F.4    Cornelio, G.H.5    Lorenzo III, C.C.6    Levy, J.P.7    Reed, R.A.8    Liu, L.9    Hall, F.L.10
  • 5
    • 76349096682 scopus 로고    scopus 로고
    • Advanced phase i/ii studies of targeted gene delivery in vivo: Intravenous rexin-g for gemcitabine-resistant metastatic pancreatic cancer
    • doi101038/mt2009228
    • Chawla SP, Chua VS, Fernandez L, Quon D, Blackwelder WC, Gordon EM, Hall FL (2010) Advanced phase I/II studies of targeted gene delivery in vivo: intravenous Rexin-G for gemcitabine-resistant metastatic pancreatic cancer. Mol Ther 18(2): 435-441. doi:10.1038/mt.2009.228
    • (2010) Mol Ther , vol.18 , Issue.2 , pp. 435-441
    • Chawla, S.P.1    Chua, V.S.2    Fernandez, L.3    Quon, D.4    Blackwelder, W.C.5    Gordon, E.M.6    Hall, F.L.7
  • 6
    • 33744818147 scopus 로고    scopus 로고
    • Effective treatment of pancreatic cancer xenografts with a conditionally replicating virus derived from type 2 herpes simplex virus
    • doi101158/1078-0432ccr-06-0045
    • Fu X, Tao L, Li M, Fisher WE, Zhang X (2006) Effective treatment of pancreatic cancer xenografts with a conditionally replicating virus derived from type 2 herpes simplex virus. Clin Cancer Res 12(10):3152-3157. doi:10.1158/1078-0432.ccr-06-0045
    • (2006) Clin Cancer Res , vol.12 , Issue.10 , pp. 3152-3157
    • Fu, X.1    Tao, L.2    Li, M.3    Fisher, W.E.4    Zhang, X.5
  • 8
    • 34250160223 scopus 로고    scopus 로고
    • Effective ablation of pancreatic cancer cells in scid mice using systemic adenoviral rip-tk/gcv gene therapy
    • Liu S-H, Davis A, Li Z, Ballian N, Davis E, Wang X-P, Fisher W, Brunicardi FC (2007) Effective ablation of pancreatic cancer cells in SCID mice using systemic adenoviral RIP-TK/GCV gene therapy. J Surg Res 141(1):45-52
    • (2007) J Surg Res , vol.141 , Issue.1 , pp. 45-52
    • Liu, S.-H.1    Davis, A.2    Li, Z.3    Ballian, N.4    Davis, E.5    Wang, X.-P.6    Fisher, W.7    Brunicardi, F.C.8
  • 10
    • 0023880478 scopus 로고
    • Transformation of human fibroblasts by ionizing radiation, a chemical carcinogen, or simian virus 40 correlates with an increase in susceptibility to the autonomous parvoviruses h-1 virus and minute virus of mice
    • Cornelis JJ, Becquart P, Duponchel N, Salome N, Avalosse BL, Namba M, Rommelaere J (1988) Transformation of human fibroblasts by ionizing radiation, a chemical carcinogen, or simian virus 40 correlates with an increase in susceptibility to the autonomous parvoviruses H-1 virus and minute virus of mice. J Virol 62(5):1679-1686
    • (1988) J Virol , vol.62 , Issue.5 , pp. 1679-1686
    • Cornelis, J.J.1    Becquart, P.2    Duponchel, N.3    Salome, N.4    Avalosse, B.L.5    Namba, M.6    Rommelaere, J.7
  • 11
    • 77951933403 scopus 로고    scopus 로고
    • Smad4: A predictive marker of pdac cell permissiveness for oncolytic infection with parvovirus h-1pv
    • doi:10.1002/ijc.24992
    • Dempe S, Stroh-Dege AY, Schwarz E, Rommelaere J, Dinsart C (2010) SMAD4: a predictive marker of PDAC cell permissiveness for oncolytic infection with parvovirus H-1PV. Int J Cancer 126(12):2914-2927. doi:10.1002/ijc.24992
    • (2010) Int J Cancer , vol.126 , Issue.12 , pp. 2914-2927
    • Dempe, S.1    Stroh-Dege, A.Y.2    Schwarz, E.3    Rommelaere, J.4    Dinsart, C.5
  • 12
    • 0019993890 scopus 로고
    • Inhibition of 7,12-dimethylbenz(a)anthracene-induced tumors in syrian hamsters by prior infection with h-1 parvovirus
    • Toolan HW, Rhode SL 3rd, Gierthy JF (1982) Inhibition of 7,12-dimethylbenz(a)anthracene-induced tumors in Syrian hamsters by prior infection with H-1 parvovirus. Cancer Res 42(7):2552-2555
    • (1982) Cancer Res , vol.42 , Issue.7 , pp. 2552-2555
    • Toolan, H.W.1    Rhode III, S.L.2    Gierthy, J.F.3
  • 15
    • 4344684036 scopus 로고    scopus 로고
    • Vectors based on autonomous parvoviruses: Novel tools to treat cancer?
    • doi:10.1002/jgm.502
    • Cornelis JJ, Salome N, Dinsart C, Rommelaere J (2004) Vectors based on autonomous parvoviruses: novel tools to treat cancer? J Gene Med 6(Suppl 1):S193-S202. doi:10.1002/jgm.502
    • (2004) J Gene Med , vol.6 , Issue.SUPPL. 1
    • Cornelis, J.J.1    Salome, N.2    Dinsart, C.3    Rommelaere, J.4
  • 16
    • 0014828716 scopus 로고
    • Minute virus of mice. Ii. Prevalence, epidemiology, and occurrence as a contaminant of transplanted tumors
    • Parker JC, Collins MJ, Jr., Cross SS, Rowe WP (1970) Minute virus of mice. II. Prevalence, epidemiology, and occurrence as a contaminant of transplanted tumors. J Natl Cancer Inst 45(2):305-310
    • (1970) J Natl Cancer Inst , vol.45 , Issue.2 , pp. 305-310
    • Parker, J.C.1    Collins Jr., M.J.2    Cross, S.S.3    Rowe, W.P.4
  • 20
    • 0034096105 scopus 로고    scopus 로고
    • Highly efficient transduction and expression of cytokine genes in human tumor cells by means of autonomous parvovirus vectors; generation of antitumor responses in recipient mice
    • doi101089/ 10430340050015789
    • Haag A, Menten P, Van Damme J, Dinsart C, Rommelaere J, Cornelis JJ (2000) Highly efficient transduction and expression of cytokine genes in human tumor cells by means of autonomous parvovirus vectors; generation of antitumor responses in recipient mice. Hum Gene Ther 11(4):597-609. doi:10.1089/ 10430340050015789
    • (2000) Hum Gene Ther , vol.11 , Issue.4 , pp. 597-609
    • Haag, A.1    Menten, P.2    Van Damme, J.3    Dinsart, C.4    Rommelaere, J.5    Cornelis, J.J.6
  • 21
    • 33846978407 scopus 로고    scopus 로고
    • Mcp-3 (ccl7) delivered by parvovirus mvmp reduces tumorigenicity of mouse melanoma cells through activation of t lymphocytes and nk cells
    • doi101002/ijc22421
    • Wetzel K, Struyf S, Van Damme J, Kayser T, Vecchi A, Sozzani S, Rommelaere J, Cornelis JJ, Dinsart C (2007) MCP-3 (CCL7) delivered by parvovirus MVMp reduces tumorigenicity of mouse melanoma cells through activation of T lymphocytes and NK cells. Int J Cancer 120(6):1364-1371. doi:10.1002/ijc.22421
    • (2007) Int J Cancer , vol.120 , Issue.6 , pp. 1364-1371
    • Wetzel, K.1    Struyf, S.2    Van Damme, J.3    Kayser, T.4    Vecchi, A.5    Sozzani, S.6    Rommelaere, J.7    Cornelis, J.J.8    Dinsart, C.9
  • 22
    • 85047696448 scopus 로고    scopus 로고
    • Suppression of metastatic hemangiosarcoma by a parvovirus mvmp vector transducing the ip-10 chemokine into immunocompetent mice
    • doi101038/sjcgt7700457
    • Giese NA, Raykov Z, DeMartino L, Vecchi A, Sozzani S, Dinsart C, Cornelis JJ, Rommelaere J (2002) Suppression of metastatic hemangiosarcoma by a parvovirus MVMp vector transducing the IP-10 chemokine into immunocompetent mice. Cancer Gene Ther 9(5):432-442. doi:10.1038/sj.cgt.7700457
    • (2002) Cancer Gene Ther , vol.9 , Issue.5 , pp. 432-442
    • Giese, N.A.1    Raykov, Z.2    DeMartino, L.3    Vecchi, A.4    Sozzani, S.5    Dinsart, C.6    Cornelis, J.J.7    Rommelaere, J.8
  • 24
    • 0032896207 scopus 로고    scopus 로고
    • Angiogenesis, angiogenic growth factors, and cell adhesion molecules are upregulated in chronic pancreatic diseases: Angiogenesis in chronic pancreatitis and in pancreatic cancer
    • Kuehn R, Lelkes PI, Bloechle C, Niendorf A, Izbicki JR (1999) Angiogenesis, angiogenic growth factors, and cell adhesion molecules are upregulated in chronic pancreatic diseases: angiogenesis in chronic pancreatitis and in pancreatic cancer. Pancreas 18(1):96-103
    • (1999) Pancreas , vol.18 , Issue.1 , pp. 96-103
    • Kuehn, R.1    Lelkes, P.I.2    Bloechle, C.3    Niendorf, A.4    Izbicki, J.R.5
  • 25
    • 4644371375 scopus 로고    scopus 로고
    • A comprehensive in vitro characterization of pancreatic ductal carcinoma cell line biological behavior and its correlation with the structural and genetic profile
    • Monti P, Marchesi F, Reni M, Mercalli A, Sordi V, Zerbi A, Balzano G, Di Carlo V, Allavena P, Piemonti L (2004) A comprehensive in vitro characterization of pancreatic ductal carcinoma cell line biological behavior and its correlation with the structural and genetic profile. Virchows Arch 445(3):236-247
    • (2004) Virchows Arch , vol.445 , Issue.3 , pp. 236-247
    • Monti, P.1    Marchesi, F.2    Reni, M.3    Mercalli, A.4    Sordi, V.5    Zerbi, A.6    Balzano, G.7    Di Carlo, V.8    Allavena, P.9    Piemonti, L.10
  • 26
    • 73649093726 scopus 로고    scopus 로고
    • The expression of il-8 and il-8 receptors in pancreatic adenocarcinomas and pancreatic neuroendocrine tumours
    • doi101016/jcyto200911010
    • Hussain F, Wang J, Ahmed R, Guest SK, Lam EW, Stamp G, El-Bahrawy M (2010) The expression of IL-8 and IL-8 receptors in pancreatic adenocarcinomas and pancreatic neuroendocrine tumours. Cytokine 49(2):134-140. doi:10.1016/j.cyto.2009. 11.010
    • (2010) Cytokine , vol.49 , Issue.2 , pp. 134-140
    • Hussain, F.1    Wang, J.2    Ahmed, R.3    Guest, S.K.4    Lam, E.W.5    Stamp, G.6    El-Bahrawy, M.7
  • 29
    • 0029155792 scopus 로고
    • Alpha and beta chemokines induce nk cell migration and enhance nkmediated cytolysis
    • Taub DD, Sayers TJ, Carter CR, Ortaldo JR (1995) Alpha and beta chemokines induce NK cell migration and enhance NKmediated cytolysis. J Immunol 155(8):3877-3888
    • (1995) J Immunol , vol.155 , Issue.8 , pp. 3877-3888
    • Taub, D.D.1    Sayers, T.J.2    Carter, C.R.3    Ortaldo, J.R.4
  • 30
    • 0035881860 scopus 로고    scopus 로고
    • Cutting edge: Selective usage of chemokine receptors by plasmacytoid dendritic cells
    • Penna G, Sozzani S, Adorini L (2001) Cutting edge: selective usage of chemokine receptors by plasmacytoid dendritic cells. J Immunol 167(4):1862-1866
    • (2001) J Immunol , vol.167 , Issue.4 , pp. 1862-1866
    • Penna, G.1    Sozzani, S.2    Adorini, L.3
  • 31
    • 0027169811 scopus 로고
    • Ip-10, a -c-x-c-chemokine, elicits a potent thymus-dependent antitumor response in vivo
    • Luster AD, Leder P (1993) IP-10, a -C-X-C-chemokine, elicits a potent thymus-dependent antitumor response in vivo. J Exp Med 178(3):1057-1065
    • (1993) J Exp Med , vol.178 , Issue.3 , pp. 1057-1065
    • Luster, A.D.1    Leder, P.2
  • 32
    • 0027368830 scopus 로고
    • Role of natural killer cells in cancer
    • Pross HF, Lotzova E (1993) Role of natural killer cells in cancer. Nat Immun 12(4-5):279-292
    • (1993) Nat Immun , vol.12 , Issue.4-5 , pp. 279-292
    • Pross, H.F.1    Lotzova, E.2
  • 33
    • 78650609261 scopus 로고    scopus 로고
    • Enhancement of nk cell anti-tumour responses using an oncolytic parvovirus
    • doi:10.1002/ijc.25415
    • Bhat R, Dempe S, Dinsart C, Rommelaere J (2011) Enhancement of NK cell anti-tumour responses using an oncolytic parvovirus. Int J Cancer 128(4):908-919. doi:10.1002/ijc.25415
    • (2011) Int J Cancer , vol.128 , Issue.4 , pp. 908-919
    • Bhat, R.1    Dempe, S.2    Dinsart, C.3    Rommelaere, J.4
  • 34
    • 0037333992 scopus 로고    scopus 로고
    • Chimeric and pseudotyped parvoviruses minimize the contamination of recombinant stocks with replication-competent viruses and identify a dna sequence that restricts parvovirus h-1 in mouse cells
    • Wrzesinski C, Tesfay L, Salome N, Jauniaux JC, Rommelaere J, Cornelis JJ, Dinsart C (2003) Chimeric and pseudotyped parvoviruses minimize the contamination of recombinant stocks with replication-competent viruses and identify a DNA sequence that restricts parvovirus H-1 in mouse cells. J Virol 77(6):3851-3858
    • (2003) J Virol , vol.77 , Issue.6 , pp. 3851-3858
    • Wrzesinski, C.1    Tesfay, L.2    Salome, N.3    Jauniaux, J.C.4    Rommelaere, J.5    Cornelis, J.J.6    Dinsart, C.7
  • 35
    • 0030059773 scopus 로고    scopus 로고
    • Activation of nk cells by cc chemokines. Chemotaxis, ca2 ? Mobilization, and enzyme release
    • Loetscher P, Seitz M, Clark-Lewis I, Baggiolini M, Moser B (1996) Activation of NK cells by CC chemokines. Chemotaxis, Ca2 ? mobilization, and enzyme release. J Immunol 156(1): 322-327
    • (1996) J Immunol , vol.156 , Issue.1 , pp. 322-327
    • Loetscher, P.1    Seitz, M.2    Clark-Lewis, I.3    Baggiolini, M.4    Moser, B.5
  • 36
    • 0031569188 scopus 로고    scopus 로고
    • Il-2-regulated expression of the monocyte chemotactic protein-1 receptor (ccr2) in human nk cells: Characterization of a predominant 3.4-kilobase transcript containing ccr2b and ccr2a sequences
    • Polentarutti N, Allavena P, Bianchi G, Giardina G, Basile A, Sozzani S, Mantovani A, Introna M (1997) IL-2-regulated expression of the monocyte chemotactic protein-1 receptor (CCR2) in human NK cells: characterization of a predominant 3.4-kilobase transcript containing CCR2B and CCR2A sequences. J Immunol 158(6):2689-2694
    • (1997) J Immunol , vol.158 , Issue.6 , pp. 2689-2694
    • Polentarutti, N.1    Allavena, P.2    Bianchi, G.3    Giardina, G.4    Basile, A.5    Sozzani, S.6    Mantovani, A.7    Introna, M.8
  • 37
    • 0023231529 scopus 로고
    • Chemotactic effect of human recombinant interleukin 2 on mouse activated large granular lymphocytes
    • Natuk RJ, Welsh RM (1987) Chemotactic effect of human recombinant interleukin 2 on mouse activated large granular lymphocytes. J Immunol 139(8):2737-2743
    • (1987) J Immunol , vol.139 , Issue.8 , pp. 2737-2743
    • Natuk, R.J.1    Welsh, R.M.2
  • 38
    • 0028589599 scopus 로고
    • Induction of natural killer cell migration by monocyte chemotactic protein-1, -2 and -3
    • doi101002/eji1830241249
    • Allavena P, Bianchi G, Zhou D, van Damme J, Jilek P, Sozzani S, Mantovani A (1994) Induction of natural killer cell migration by monocyte chemotactic protein-1, -2 and -3. Eur J Immunol 24(12):3233-3236. doi:10.1002/eji.1830241249
    • (1994) Eur J Immunol , vol.24 , Issue.12 , pp. 3233-3236
    • Allavena, P.1    Bianchi, G.2    Zhou, D.3    Van Damme, J.4    Jilek, P.5    Sozzani, S.6    Mantovani, A.7
  • 39
    • 0030851572 scopus 로고    scopus 로고
    • Interferon-inducible protein-10 and lymphotactin induce the chemotaxis and mobilization of intracellular calcium in natural killer cells through pertussis toxin-sensitive and -insensitive heterotrimeric g-proteins
    • Maghazachi AA, Skalhegg BS, Rolstad B, Al-Aoukaty A (1997) Interferon-inducible protein-10 and lymphotactin induce the chemotaxis and mobilization of intracellular calcium in natural killer cells through pertussis toxin-sensitive and -insensitive heterotrimeric G-proteins. FASEB J 11(10):765-774
    • (1997) FASEB J , vol.11 , Issue.10 , pp. 765-774
    • Maghazachi, A.A.1    Skalhegg, B.S.2    Rolstad, B.3    Al-Aoukaty, A.4
  • 40
    • 14044250981 scopus 로고    scopus 로고
    • Codon-optimized gaussia luciferase cdna for mammalian gene expression in culture and in vivo
    • Tannous BA, Kim D-E, Fernandez JL, Weissleder R, Breakefield XO (2005) Codon-optimized Gaussia luciferase cDNA for mammalian gene expression in culture and in vivo. Mol Ther 11(3):435-443
    • (2005) Mol Ther , vol.11 , Issue.3 , pp. 435-443
    • Tannous, B.A.1    Kim, D.-E.2    Fernandez, J.L.3    Weissleder, R.4    Breakefield, X.O.5
  • 41
    • 0026721539 scopus 로고
    • Structural and functional identification of two human, tumorderived monocyte chemotactic proteins (mcp-2 and mcp-3) belonging to the chemokine family
    • Van Damme J, Proost P, Lenaerts JP, Opdenakker G (1992) Structural and functional identification of two human, tumorderived monocyte chemotactic proteins (MCP-2 and MCP-3) belonging to the chemokine family. J Exp Med 176(1):59-65
    • (1992) J Exp Med , vol.176 , Issue.1 , pp. 59-65
    • Van Damme, J.1    Proost, P.2    Lenaerts, J.P.3    Opdenakker, G.4
  • 43
    • 0036607954 scopus 로고    scopus 로고
    • Cd83 on dendritic cells: More than just a marker for maturation
    • Lechmann M, Berchtold S, Hauber J, Steinkasserer A (2002) CD83 on dendritic cells: more than just a marker for maturation. Trends Immunol 23(6):273-275
    • (2002) Trends Immunol , vol.23 , Issue.6 , pp. 273-275
    • Lechmann, M.1    Berchtold, S.2    Hauber, J.3    Steinkasserer, A.4
  • 45
    • 67650165335 scopus 로고    scopus 로고
    • Interleukin-2: Evaluation of routes of administration and current delivery systems in cancer therapy
    • doi101002/js21596
    • Shaker MA, Younes HM (2009) Interleukin-2: evaluation of routes of administration and current delivery systems in cancer therapy. J Pharm Sci 98(7):2268-2298. doi:10.1002/jps.21596
    • (2009) J Pharm Sci , vol.98 , Issue.7 , pp. 2268-2298
    • Shaker, M.A.1    Younes, H.M.2
  • 46
    • 51049100187 scopus 로고    scopus 로고
    • The targeted immunocytokine l19-il2 efficiently inhibits the growth of orthotopic pancreatic cancer
    • doi101158/1078-0432CCR-08-0157
    • Wagner K, Schulz P, Scholz A, Wiedenmann B, Menrad A (2008) The targeted immunocytokine L19-IL2 efficiently inhibits the growth of orthotopic pancreatic cancer. Clin Cancer Res 14(15):4951-4960. doi:10.1158/1078-0432.CCR-08-0157
    • (2008) Clin Cancer Res , vol.14 , Issue.15 , pp. 4951-4960
    • Wagner, K.1    Schulz, P.2    Scholz, A.3    Wiedenmann, B.4    Menrad, A.5
  • 47
    • 55849105191 scopus 로고    scopus 로고
    • Interleukin-2 immunotherapy action on innate immunity cells in peripheral blood and tumoral tissue of pancreatic adenocarcinoma patients
    • doi101007/s00423-0080393-0394
    • Degrate L, Nobili C, Franciosi C, Caprotti R, Brivio F, Romano F, Leone BE, Trezzi R, Uggeri F (2009) Interleukin-2 immunotherapy action on innate immunity cells in peripheral blood and tumoral tissue of pancreatic adenocarcinoma patients. Langenbecks Arch Surg 394(1):115-121. doi:10.1007/s00423-008-0393-4
    • (2009) Langenbecks Arch Surg , vol.394 , Issue.1 , pp. 115-121
    • Degrate, L.1    Nobili, C.2    Franciosi, C.3    Caprotti, R.4    Brivio, F.5    Romano, F.6    Leone, B.E.7    Trezzi, R.8    Uggeri, F.9
  • 48
    • 7144253145 scopus 로고    scopus 로고
    • Reduced tumorigenicity and augmented leukocyte infiltration after monocyte chemotactic protein-3 (mcp-3) gene transfer: Perivascular accumulation of dendritic cells in peritumoral tissue and neutrophil recruitment within the tumor
    • Fioretti F, Fradelizi D, Stoppacciaro A, Ramponi S, Ruco L, Minty A, Sozzani S, Garlanda C, Vecchi A, Mantovani A (1998) Reduced tumorigenicity and augmented leukocyte infiltration after monocyte chemotactic protein-3 (MCP-3) gene transfer: perivascular accumulation of dendritic cells in peritumoral tissue and neutrophil recruitment within the tumor. J Immunol 161(1):342-346
    • (1998) J Immunol , vol.161 , Issue.1 , pp. 342-346
    • Fioretti, F.1    Fradelizi, D.2    Stoppacciaro, A.3    Ramponi, S.4    Ruco, L.5    Minty, A.6    Sozzani, S.7    Garlanda, C.8    Vecchi, A.9    Mantovani, A.10
  • 49
    • 45549091996 scopus 로고    scopus 로고
    • Additive roles for mcp-1 and mcp-3 in ccr2-mediated recruitment of inflammatory monocytes during listeria monocytogenes infection
    • Jia T, Serbina NV, Brandl K, Zhong MX, Leiner IM, Charo IF, Pamer EG (2008) Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection. J Immunol 180(10):6846-6853
    • (2008) J Immunol , vol.180 , Issue.10 , pp. 6846-6853
    • Jia, T.1    Serbina, N.V.2    Brandl, K.3    Zhong, M.X.4    Leiner, I.M.5    Charo, I.F.6    Pamer, E.G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.