ABCG2/V-ATPase was associated with the drug resistance and tumor metastasis of esophageal squamous cancer cells

Diagnostic Pathology

Volumn 7, Issue 1, 2012, Pages

  Huang, Lijun ^a   Lu, Qiang ^a   Han, Yong ^a   Li, Zhe ^b   Zhang, Zhipei ^a   Li, Xiaofei ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b The Ninth Hospital of Xi'an City   (China)

Author keywords

ABCG2; Drug resistance; Esophageal carcinoma; Squamous cell carcinoma; V ATPase

Indexed keywords

ABC TRANSPORTER; ABCG2 PROTEIN, HUMAN; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; TUMOR MARKER; TUMOR PROTEIN;

ADULT; AGED; ARTICLE; CANCER GRADING; CANCER STAGING; CELL MEMBRANE; CYTOPLASM; DRUG RESISTANCE; ENZYMOLOGY; ESOPHAGUS TUMOR; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; IMMUNOHISTOCHEMISTRY; MALE; METASTASIS; MIDDLE AGED; PATHOLOGY; PROGNOSIS; SQUAMOUS CELL CARCINOMA; UPREGULATION;

ADULT; AGED; ATP-BINDING CASSETTE TRANSPORTERS; CARCINOMA, SQUAMOUS CELL; CELL MEMBRANE; CYTOPLASM; DRUG RESISTANCE, NEOPLASM; ESOPHAGEAL NEOPLASMS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM PROTEINS; NEOPLASM STAGING; PROGNOSIS; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION; VACUOLAR PROTON-TRANSLOCATING ATPASES;

MLCS; MLOWN;

EID: 84870981309     PISSN: None     EISSN: 17461596     Source Type: Journal    
DOI: 10.1186/1746-1596-7-180     Document Type: Article

References (19)

1. Kuo MT. Redox regulation of multidrug resistance in cancer chemotherapy: molecular mechanisms and therapeutic opportunities. Antioxid Redox Signal 2009, 11:99-133. 10.1089/ars.2008.2095, 2577715, 18699730.
2. Szakacs G, Varadi A, Ozvegy-Laczka C, Sarkadi B. The role of ABC transporters in drug absorption, distribution, metabolism, excretion and toxicity (ADME-Tox). Drug Discov Today 2008, 13:379-393. 10.1016/j.drudis.2007.12.010, 18468555.
3. Huang Y, Sadee W. Membrane transporters and channels in chemoresistance and -sensitivity of tumor cells. Cancer Lett 2006, 239:168-182. 10.1016/j.canlet.2005.07.032, 16169662.
4. Koshiba S, An R, Saito H, Wakabayashi K, Tamura A, Ishikawa T. Human ABC transporters ABCG2 (BCRP) and ABCG4. Xenobiotica 2008, 38:863-888. 10.1080/00498250801986944, 18668433.
5. Ishikawa T, Nakagawa H. Human ABC transporter ABCG2 in cancer chemotherapy and pharmacogenomics. J Exp Ther Oncol 2009, 8:5-24.
6. Qing C, Siwei Z, Rongshou Z, Zhenglong L, Guangbin L, Xiaonong Z, Ping Z. A report of cancer incidence and mortality from 38 cancer registries in China, 2007. China Cancer 2011, 20:162-169.
7. Crosby TD, Evans M. Resectable oesophageal cancer: a practice guideline update. Practice changing or supporting the status quo?. Clin Oncol (R Coll Radiol) 2010, 22:247-249.
8. Luzna P, Gregar J, Uberall I, Radova L, Prochazka V, Ehrmann J. Changes of microRNAs-192, 196a and 203 correlate with Barrett's esophagus diagnosis and its progression compared to normal healthy individuals. Diagn Pathol 2011, 6:114. 10.1186/1746-1596-6-114, 3268741, 22094011.
9. Wang JB, Fan JH, Liang H, Li J, Xiao HJ, Wei WQ, Dawsey SM, Qiao YL, Boffetta P. Attributable causes of esophageal cancer incidence and mortality in China. PLoS One 2012, 7:e42281. 10.1371/journal.pone.0042281, 3410925, 22876312.
10. Langer R, Specht K, Becker K, Ewald P, Bekesch M, Sarbia M, Busch R, Feith M, Stein HJ, Siewert JR, Hofler H. Association of pretherapeutic expression of chemotherapy-related genes with response to neoadjuvant chemotherapy in Barrett carcinoma. Clin Cancer Res 2005, 11:7462-7469. 10.1158/1078-0432.CCR-05-0042, 16243820.
11. Demel MA, Schwaha R, Kramer O, Ettmayer P, Haaksma EE, Ecker GF. In silico prediction of substrate properties for ABC-multidrug transporters. Expert Opin Drug Metab Toxicol 2008, 4:1167-1180. 10.1517/17425255.4.9.1167, 18721111.
12. Ortiz CM, Ito T, Hashimoto Y, Nagayama S, Iwai A, Tsunoda S, Sato F, Martorell M, Garcia JA, Perez A, Shimada Y. Effects of small interfering RNAs targeting fascin on human esophageal squamous cell carcinoma cell lines. Diagn Pathol 2010, 5:41. 10.1186/1746-1596-5-41, 2907320, 20565981.
13. Marchetti S, de Vries NA, Buckle T, Bolijn MJ, van Eijndhoven MA, Beijnen JH, Mazzanti R, van Tellingen O, Schellens JH. Effect of the ATP-binding cassette drug transporters ABCB1, ABCG2, and ABCC2 on erlotinib hydrochloride (Tarceva) disposition in in vitro and in vivo pharmacokinetic studies employing Bcrp1-/-/Mdr1a/1b-/- (triple-knockout) and wild-type mice. Mol Cancer Ther 2008, 7:2280-2287. 10.1158/1535-7163.MCT-07-2250, 18723475.
14. Gandhi YA, Morris ME. Structure-activity relationships and quantitative structure-activity relationships for breast cancer resistance protein (ABCG2). AAPS J 2009, 11:541-552. 10.1208/s12248-009-9132-1, 2758125, 19629710.
15. Evseenko DA, Paxton JW, Keelan JA. Independent regulation of apical and basolateral drug transporter expression and function in placental trophoblasts by cytokines, steroids, and growth factors. Drug Metab Dispos 2007, 35:595-601. 10.1124/dmd.106.011478, 17237156.
16. Sukocheva OA, Wee C, Ansar A, Hussey DJ, Watson DI. Effect of estrogen on growth and apoptosis in esophageal adenocarcinoma cells. Dis Esophagus 2012,
17. Ding XW, Wu JH, Jiang CP. ABCG2: a potential marker of stem cells and novel target in stem cell and cancer therapy. Life Sci 2010, 86:631-637. 10.1016/j.lfs.2010.02.012, 20159023.
18. Fais S, De Milito A, You H, Qin W. Targeting vacuolar H + -ATPases as a new strategy against cancer. Cancer Res 2007, 67:10627-10630. 10.1158/0008-5472.CAN-07-1805, 18006801.
19. Breedveld P, Pluim D, Cipriani G, Dahlhaus F, van Eijndhoven MA, de Wolf CJ, Kuil A, Beijnen JH, Scheffer GL, Jansen G, et al. The effect of low pH on breast cancer resistance protein (ABCG2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mitoxantrone, topotecan, and resveratrol in in vitro drug transport models. Mol Pharmacol 2007, 71:240-249.