메뉴 건너뛰기




Volumn 11, Issue 5, 2012, Pages 426-432

[18F]-29-fluoro-5-methyl-1-beta-D-arabinofuranosyluracil ( 18F-FMAU) in prostate cancer: Initial preclinical observations

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN RECEPTORS; ATHYMIC; BIODISTRIBUTIONS; CELLULAR PROLIFERATIONS; EMISSION TOMOGRAPHY; HUMAN PROSTATE CANCER; HUMAN PROSTATE CANCER CELLS; IMMUNOHISTOCHEMICAL STAINING; MALE MOUSE; MOUSE MODELS; PROSTATE CANCERS; PROSTATE TUMOR; TIME POINTS; TUMOR CHARACTERIZATION; TUMOR UPTAKE;

EID: 84870976337     PISSN: 15353508     EISSN: None     Source Type: Journal    
DOI: 10.2310/7290.2012.00004     Document Type: Article
Times cited : (12)

References (25)
  • 1
    • 79851481116 scopus 로고    scopus 로고
    • Prostate cancer: PET with 18F-FDG, 18F- or 11C-acetate, and 18F- or 11C-choline
    • doi:10.2967/ jnumed.110.077941
    • Jadvar H. Prostate cancer: PET with 18F-FDG, 18F- or 11C-acetate, and 18F- or 11C-choline. J Nucl Med 2010;52:81-9, doi:10.2967/ jnumed.110.077941.
    • (2010) J Nucl Med , vol.52 , pp. 81-89
    • Jadvar, H.1
  • 2
    • 57149084500 scopus 로고    scopus 로고
    • Novel tracers and their development for the imaging of metastatic prostate cancer
    • doi:10.2967/jnumed.108.050658
    • Apolo AB, Pandit-Taskar N, Morris MJ. Novel tracers and their development for the imaging of metastatic prostate cancer. J Nucl Med 2008;49:2031-41, doi:10.2967/jnumed.108.050658.
    • (2008) J Nucl Med , vol.49 , pp. 2031-2041
    • Apolo, A.B.1    Pandit-Taskar, N.2    Morris, M.J.3
  • 3
    • 33746920876 scopus 로고    scopus 로고
    • Positron emission tomography measurement of tumor metabolism and growth: Its expanding role in oncology
    • doi:10.1007/s11307-006-0039-2
    • Shields AF. Positron emission tomography measurement of tumor metabolism and growth: its expanding role in oncology. Mol Imaging Biol 2006;8:141-50, doi:10.1007/s11307-006-0039-2.
    • (2006) Mol Imaging Biol , vol.8 , pp. 141-150
    • Shields, A.F.1
  • 4
    • 48149084561 scopus 로고    scopus 로고
    • Tracking cellular stress with labeled FMAU reflects changes in mitochondrial TK2
    • doi:10.1007/ s00259-008-0738-0739
    • Tehrani OS, Douglas KA, Lawhom-Crews JM, et al. Tracking cellular stress with labeled FMAU reflects changes in mitochondrial TK2. Eur J Nucl Med Mol Imaging 2008;35:1480-8, doi:10.1007/ s00259-008-0738-9.
    • (2008) Eur J Nucl Med Mol Imaging , vol.35 , pp. 1480-1488
    • Tehrani, O.S.1    Douglas, K.A.2    Lawhom-Crews, J.M.3
  • 5
    • 0021934355 scopus 로고
    • Phase i trial of 1-(29-deoxy-29-fluoro-1-beta-D-arabinofuranosyl) 5-methyluracil (FMAU)
    • Fanucchi MP, Leyland-Jones R, Young CW, et al. Phase I trial of 1-(29-deoxy-29-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU). Cancer Treat Rep 1985;69:55-9.
    • (1985) Cancer Treat Rep , vol.69 , pp. 55-59
    • Fanucchi, M.P.1    Leyland-Jones, R.2    Young, C.W.3
  • 6
    • 0029064884 scopus 로고
    • Synthesis of 29-fluoro-5- [11C]-methyl-1-beta-D-arabinofurasyluracil ([11C]-FMAU): A potential nucleoside analog for in vivo study of cellular proliferation with PET
    • doi:10.1016/0969- 8051(95)00017-R
    • Conti PS, AlauddinMM, Fissekis JR, et al. Synthesis of 29-fluoro-5- [11C]-methyl-1-beta-D-arabinofurasyluracil ([11C]-FMAU): a potential nucleoside analog for in vivo study of cellular proliferation with PET. Nucl Med Biol 1995;22:783-9, doi:10.1016/0969- 8051(95)00017-R.
    • (1995) Nucl Med Biol , vol.22 , pp. 783-789
    • Conti, P.S.1    Alauddin, M.M.2    Fissekis, J.R.3
  • 7
    • 0034181442 scopus 로고    scopus 로고
    • Pharmacokinetics of the thymidine analog 29-fluoro-5-[( 14) C]-methyl-1-beta-D-arabinofuranosyluracil ([(14)C]FMAU in rat prostate tumor cell
    • doi:10.1016/S0969-8051(00)00100-1
    • Bading JR, Shahinian AH, Bathija P, et al. Pharmacokinetics of the thymidine analog 29-fluoro-5-[(14)C]-methyl-1-beta-D-arabinofuranosyluracil ([(14)C]FMAU in rat prostate tumor cell. Nucl Med Biol 2000;27:361-8, doi:10.1016/S0969-8051(00)00100-1.
    • (2000) Nucl Med Biol , vol.27 , pp. 361-368
    • Bading, J.R.1    Shahinian, A.H.2    Bathija, P.3
  • 8
    • 0036010962 scopus 로고    scopus 로고
    • Radiolabeled 29-fluorodeoxyuracilbeat- D-arabinofuranoside (FAU) and 29-fluoro-5-methyldeoxyuracil- beta-D-arabinofuranoside (FMAU) as tumor imaging agents in mice
    • doi:10.1007/s00280-002-0433-7
    • Wang H, Oliver P, Nan L, et al. Radiolabeled 29-fluorodeoxyuracilbeat- D-arabinofuranoside (FAU) and 29-fluoro-5-methyldeoxyuracil- beta-D-arabinofuranoside (FMAU) as tumor imaging agents in mice. Cancer Chemother Pharmacol 2002;49:419-24, doi:10.1007/s00280-002-0433-7.
    • (2002) Cancer Chemother Pharmacol , vol.49 , pp. 419-424
    • Wang, H.1    Oliver, P.2    Nan, L.3
  • 9
    • 0036900006 scopus 로고    scopus 로고
    • Rat studies comparing 11C-FMAU, 18F-FLT, and 76Br-BFU as proliferation markers
    • Lu L, Samuelsson L, Bergstrom M, et al. Rat studies comparing 11C-FMAU, 18F-FLT, and 76Br-BFU as proliferation markers. J Nucl Med 2002;43:1688-98.
    • (2002) J Nucl Med , vol.43 , pp. 1688-1698
    • Lu, L.1    Samuelsson, L.2    Bergstrom, M.3
  • 10
    • 0038735303 scopus 로고    scopus 로고
    • Synthesis of 29-deoxy- 29-[18F]fluoro-beta-D-arabinofuranosyl nucleosides, [18F]FAU, [18F]FMAU, [18F]FBAU and [18F]FIAU, as potential PET agents for imaging cellular proliferation Synthesis of [18F] labeled FAU, FMAU, FBAU, FIAU
    • doi:10.1016/ S0969-8051(02) 00445-00446
    • Mangner TJ, Klecker RW, Anderson L, et al. Synthesis of 29-deoxy- 29-[18F]fluoro-beta-D-arabinofuranosyl nucleosides, [18F]FAU, [18F]FMAU, [18F]FBAU and [18F]FIAU, as potential PET agents for imaging cellular proliferation. Synthesis of [18F] labeled FAU, FMAU, FBAU, FIAU. Nucl Med Biol 2003;30:215-24, doi:10.1016/ S0969-8051(02)00445-6.
    • (2003) Nucl Med Biol , vol.30 , pp. 215-224
    • Mangner, T.J.1    Klecker, R.W.2    Anderson, L.3
  • 11
    • 0033625201 scopus 로고    scopus 로고
    • [(11)C]FMAU and [(18)F]FHPG as PET tracers for herpes simplex virus thymidine kinase activity and human cytomegalovirus infections
    • doi:10.1016/S0969-8051 (99)00105-00105
    • de Vries EF, van Waarde A, Harmsen MC, et al. [(11)C]FMAU and [(18)F]FHPG as PET tracers for herpes simplex virus thymidine kinase activity and human cytomegalovirus infections. Nucl Med Biol 2000;27:113-9, doi:10.1016/S0969-8051 (99)00105-5.
    • (2000) Nucl Med Biol , vol.27 , pp. 113-119
    • De Vries, E.F.1    Van Waarde, A.2    Harmsen, M.C.3
  • 12
    • 0042473079 scopus 로고    scopus 로고
    • Evaluation of 29-deoxy-29-fluoro-5-methyl-1-beta-D-arabinofurasyluracil as a potential gene imaging agent for HSV-tk expression in vivo
    • doi:10.1162/153535002320162723
    • Alauddin MM, Shahinian A, Gordon EM, et al. Evaluation of 29-deoxy-29-fluoro-5-methyl-1-beta-D-arabinofurasyluracil as a potential gene imaging agent for HSV-tk expression in vivo. Mol Imaging 2002;1:74-81, doi:10.1162/153535002320162723.
    • (2002) Mol Imaging , vol.1 , pp. 74-81
    • Alauddin, M.M.1    Shahinian, A.2    Gordon, E.M.3
  • 13
    • 4644294588 scopus 로고    scopus 로고
    • Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model
    • doi:10.1162/1535350041464900
    • Alauddin MM, Shahinian A, Gordon EM, et al. Direct comparison of radiolabeled probes FMAU, FHBG, and FHPG as PET imaging agents for HSV1-tk expression in a human breast cancer model. Mol Imaging 2004;3:76-84, doi:10.1162/1535350041464900.
    • (2004) Mol Imaging , vol.3 , pp. 76-84
    • Alauddin, M.M.1    Shahinian, A.2    Gordon, E.M.3
  • 14
    • 33646787078 scopus 로고    scopus 로고
    • Comparison of [14C]FMAU, [3H]FEAU, [14C]FIAU, and [3H]PCV for monitoring reporter gene expression of wild type and mutant herpes simplex virus type i thymidine kinase in cell culture
    • doi:10.1007/s11307-005-0010-7
    • Kang KW, Min JJ, Chen X, et al. Comparison of [14C]FMAU, [3H]FEAU, [14C]FIAU, and [3H]PCV for monitoring reporter gene expression of wild type and mutant herpes simplex virus type I thymidine kinase in cell culture. Mol Imaging Biol 2005;7:296- 303, doi:10.1007/s11307-005-0010-7.
    • (2005) Mol Imaging Biol , vol.7 , pp. 296-303
    • Kang, K.W.1    Min, J.J.2    Chen, X.3
  • 15
    • 15844429409 scopus 로고    scopus 로고
    • Imaging DNA synthesis in vivo with 18F-FMAU and PET
    • Sun H, Mangner TJ, Collins JM, et al. Imaging DNA synthesis in vivo with 18F-FMAU and PET. J Nucl Med 2005;46:292-6.
    • (2005) J Nucl Med , vol.46 , pp. 292-296
    • Sun, H.1    Mangner, T.J.2    Collins, J.M.3
  • 16
    • 79651471152 scopus 로고    scopus 로고
    • Automated synthesis of 29-deoxy-29- [18F]fluoro-5-methyl-1-b-D- arabinofuranosyluracil ([18F]-FMAU) using a one reactor radiosynthesis module
    • doi:10.1016/j.nucmedbio.2010.08.010
    • Li Z, Cai H, Conti PS. Automated synthesis of 29-deoxy-29- [18F]fluoro-5-methyl-1-b-D-arabinofuranosyluracil ([18F]-FMAU) using a one reactor radiosynthesis module. Nucl Med Biol 2011;38: 201-6, doi:10.1016/j.nucmedbio.2010.08.010.
    • (2011) Nucl Med Biol , vol.38 , pp. 201-206
    • Li, Z.1    Cai, H.2    Conti, P.S.3
  • 17
    • 0036282024 scopus 로고    scopus 로고
    • Comparison of [18F]fluorocholine and [18F]fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer
    • doi:10.1016/S0022-5347(05)64906-3
    • Price DT, Coleman RE, Liao R, et al. Comparison of [18F]fluorocholine and [18F]fluorodeoxyglucose for positron emission tomography of androgen dependent and androgen independent prostate cancer. J Urol 2002;168:273-80, doi:10.1016/S0022-5347(05)64906-3.
    • (2002) J Urol , vol.168 , pp. 273-280
    • Price, D.T.1    Coleman, R.E.2    Liao, R.3
  • 18
    • 0742306937 scopus 로고    scopus 로고
    • Parasagittal biopsies add minimal information in repeat saturation prostate biopsy
    • doi:10.1016/j.urology.2003.08.040
    • Patel A, Jones J, Rabets J, et al. Parasagittal biopsies add minimal information in repeat saturation prostate biopsy. Urology 2004;63: 87-9, doi:10.1016/j.urology.2003.08.040.
    • (2004) Urology , vol.63 , pp. 87-89
    • Patel, A.1    Jones, J.2    Rabets, J.3
  • 19
    • 40649123807 scopus 로고    scopus 로고
    • Saturation prostate biopsy in high risk patients after multiple previous negative biopsies
    • doi:10.1016/j.urology.2007.11.007
    • Stav K, Liebovici D, Sandbank J, et al. Saturation prostate biopsy in high risk patients after multiple previous negative biopsies. Urology 2008;71:399403, doi:10.1016/j.urology.2007.11.007.
    • (2008) Urology , vol.71 , pp. 399403
    • Stav, K.1    Liebovici, D.2    Sandbank, J.3
  • 20
    • 46749137956 scopus 로고    scopus 로고
    • Imaging of cell proliferation: Status and prospects
    • doi:10.2967/jnumed. 107.046391
    • Bading JR, Shields A. Imaging of cell proliferation: status and prospects. J Nucl Med 2008;49:64S-80S, doi:10.2967/jnumed. 107.046391.
    • (2008) J Nucl Med , vol.49
    • Bading, J.R.1    Shields, A.2
  • 21
    • 85027935817 scopus 로고    scopus 로고
    • Early response assessment in prostate carcinoma by 18F-fluorothymidine following anticancer therapy with docetaxel using preclinical tumor models
    • doi:10.1007/s00259-010-1613-z
    • Oyama N, Hasegawa Y, Kiyono Y. Early response assessment in prostate carcinoma by 18F-fluorothymidine following anticancer therapy with docetaxel using preclinical tumor models. Eur J Nucl Med Mol Imaging 2011;38:81-9, doi:10.1007/s00259-010-1613-z.
    • (2011) Eur J Nucl Med Mol Imaging , vol.38 , pp. 81-89
    • Oyama, N.1    Hasegawa, Y.2    Kiyono, Y.3
  • 22
    • 0033520806 scopus 로고    scopus 로고
    • Prostate cancer cell cycle regulators: Response to androgen withdrawal and development of androgen independence
    • doi:10.1093/jnci/91.21.1869
    • Agus DB, Cordon-Cardo C, Fox W, Drobnjak M, et al. Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence. J Natl Cancer Inst 1999; 91:1869-76, doi:10.1093/jnci/91.21.1869.
    • (1999) J Natl Cancer Inst , vol.91 , pp. 1869-1876
    • Agus, D.B.1    Cordon-Cardo, C.2    Fox, W.3    Drobnjak, M.4
  • 23
    • 0036141411 scopus 로고    scopus 로고
    • Androgen receptor expression and cellular proliferation during transition from androgen-dependent to recurrent growth after castration in CWR22 prostate xenograft
    • doi:10.1016/S0002-9440(10)64365-9
    • Kim D, Gregory CW, French FS, et al. Androgen receptor expression and cellular proliferation during transition from androgen-dependent to recurrent growth after castration in CWR22 prostate xenograft. Am J Pathol 2002;160:219-26, doi:10.1016/S0002-9440(10)64365-9.
    • (2002) Am J Pathol , vol.160 , pp. 219-226
    • Kim, D.1    Gregory, C.W.2    French, F.S.3
  • 24
    • 0015352254 scopus 로고
    • Androgen control of mitochondrial and nuclear DNA synthesis in male sex accessory tissue of castrate rats
    • 8, doi:10.1210/ endo-90-6-1633
    • Doeg KA, Polomski LL, Doeg LH. Androgen control of mitochondrial and nuclear DNA synthesis in male sex accessory tissue of castrate rats. Endocrinology 1972;90:1633-8, doi:10.1210/ endo-90-6-1633.
    • (1972) Endocrinology , vol.90 , Issue.1633
    • Doeg, K.A.1    Polomski, L.L.2    Doeg, L.H.3
  • 25
    • 42949126281 scopus 로고    scopus 로고
    • The current state of preclinical prostate cancer animal models
    • doi:10.1002/pros.20726
    • Pienta KJ, Abate-Shen C, Agus DB, et al. The current state of preclinical prostate cancer animal models. Prostate 2008;68:629- 39, doi:10.1002/pros. 20726.
    • (2008) Prostate , vol.68 , pp. 629-639
    • Pienta, K.J.1    Abate-Shen, C.2    Agus, D.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.