Glucocorticoids Affect 24 h Clock Genes Expression in Human Adipose Tissue Explant Cultures

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Gómez Abellán, Purificación ^a   Díez Noguera, Antoni ^b   Madrid, Juan A ^a   Luján, Juan A ^c   Ordovás, José M ^d,e,f   Garaulet, Marta ^a  

^a UNIVERSITY OF MURCIA   (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

^c HOSPITAL UNIVERSITARIO VIRGEN DE LA ARRIXACA   (Spain)

^d TUFTS UNIVERSITY   (United States)

^e CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CNIC   (Spain)

^f IMDEA FOOD INSTITUTE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE; MESSENGER RNA; PER2 PROTEIN; PROTEIN BMAL1; TRANSCRIPTION FACTOR CLOCK;

ADULT; ARTICLE; BMAL1 GENE; BODY MASS; CIRCADIAN RHYTHM; CLOCK GENE; CONTROLLED STUDY; EXPLANT; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENE LOCATION; HORMONE RESPONSE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INCUBATION TIME; INTRAABDOMINAL FAT; MORBID OBESITY; PER2 GENE; SUBCUTANEOUS FAT; TISSUE CULTURE CELL; TISSUE DISTRIBUTION;

ADIPOSE TISSUE; ADULT; ARNTL TRANSCRIPTION FACTORS; BODY MASS INDEX; CIRCADIAN RHYTHM; CLOCK PROTEINS; DEXAMETHASONE; FEMALE; GENE EXPRESSION REGULATION; GLUCOCORTICOIDS; HUMANS; MIDDLE AGED; OBESITY, MORBID; PERIOD CIRCADIAN PROTEINS; RNA, MESSENGER;

EID: 84870937627     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050435     Document Type: Article

References (34)

1. Reppert SM, Weaver DR, (2002) Coordination of circadian timing in mammals. Nature 418 (6901):: 935-41.
2. Lee C, Etchegaray JP, Cagampang FR, Loudon AS, Reppert SM, (2001) Posttranslational mechanisms regulate the mammalian circadian clock. Cell 107 (7):: 855-67.
3. Gómez-Santos C, Gómez-Abellán P, Madrid JA, Hernández-Morante JJ, Lujan JA, et al. (2009) Circadian rhythm of clock genes in human adipose explants. Obesity (Silver Spring) 17 (8):: 1481-5.
4. Vitaterna MH, King DP, Chang AM, Kornhauser JM, Lowrey PL, et al. (1994) Mutagenesis and mapping of a mouse gene, Clock, essential for circadian behavior. Science 264 (5159):: 719-25.
5. Turek FW, Joshu C, Kohsaka A, Lin E, Ivanova G, et al. (2005) Obesity and metabolic syndrome in circadian Clock mutant mice. Science 308 (5724):: 1043-5.
6. Garaulet M, Lee YC, Shen J, Parnell LD, Arnett DK, et al. (2009) CLOCK genetic variation and metabolic syndrome risk: modulation by monounsaturated fatty acids. Am J Clin Nutr 90 (6):: 1466-75.
7. Scott EM, Carter AM, Grant PJ, (2008) Association between polymorphisms in the Clock gene, obesity and the metabolic syndrome in man. Int J Obes (Lond) 32: 658-662.
8. Sookoian S, Gemma C, Gianotti TF, Burgueno A, Castano G, et al. (2008) Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity. Am J Clin Nutr 87: 1606-1615.
9. Garaulet M, Corbalán MD, Madrid JA, Morales E, Baraza JC, et al. (2010) CLOCK gene is implicated in weight reduction in obese patients participating in a dietary programme based on the Mediterranean diet. Int J Obes (Lond) 34 (3):: 516-23.
10. Balsalobre A, Brown SA, Marcacci L, Tronche F, Kellendonk C, et al. (2000) Resetting of circadian time in peripheral tissues by glucocorticoid signaling. Science 289 (5488):: 2344-7.
11. Burioka N, Fukuoka Y, Koyanagi S, Miyata M, Takata M, et al. (2010) Asthma: Chronopharmacotherapy and the molecular clock. Adv Drug Deliv Rev 62 (9-10):: 946-55.
12. Wu X, Zvonic S, Floyd ZE, Kilroy G, Goh BC, et al. (2007) Induction of circadian gene expression in human subcutaneous adipose-derived stem cells. Obesity (Silver Spring) 15 (11):: 2560-70.
13. Garaulet M, Hernández-Morante JJ, Tébar FJ, Zamora S, Canteras M, (2006) Two-dimensional predictive equation to classify visceral obesity in clinical practice. Obesity (Silver Spring) 14: 1181-1191.
14. Harris JA, Benedict FG, (1918) A Biometric Study of Human Basal Metabolism. Proc Natl Acad Sci U S A 4 (12):: 370-3.
15. Livak KJ, Schmittgen TD, (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2 (-Delta Delta C(T)) Method. Methods 25: 402-408.
16. Batschelet E (1981) Circular Statistics in Biology. Academic Press, London.
17. Alberti KG, Zimmet P, Shaw J, (2006) Metabolic syndrome a new wold-wide definition. A Consensus Statement from the International Diabetes Federation. Diabet Med 23: 469-480.
18. Hernandez-Morante JJ, Gomez-Santos C, Milagro F, Campión J, Martínez JA, et al. (2009) Expression of cortisol metabolism-related genes shows circadian rhythmic patterns in human adipose tissue. Int J Obes (Lond) 33: 473-480.
19. Gómez-Abellán P, Gómez-Santos C, Madrid JA, Milagro FI, Campion J, et al. (2010) Circadian expression of adiponectin and its receptors in human adipose tissue. Endocrinology 151 (1):: 115-22.
20. Gómez Abellán P, Gómez Santos C, Madrid JA, Milagro FI, Campion J, et al. (2011) Site-specific circadian expression of leptin and its receptor in human adipose tissue. Nutr Hosp 26 (6):: 1394-1401.
21. Lee MJ, Gong DW, Burkey BF, Fried SK, (2011) Pathways regulated by glucocorticoids in omental and subcutaneous human adipose tissues: a microarray study. Am J Physiol Endocrinol Metab 300 (3):: E571-80.
22. Veilleux A, Laberge PY, Morency J, Noël S, Luu-The V, et al. (2010) Expression of genes related to glucocorticoid action in human subcutaneous and omental adipose tissue. J Steroid Biochem Mol Biol 122 (1-3):: 28-34.
23. Tanaka K, Ashizawa N, Kawano H, Sato O, Seto S, et al. (2007) Aldosterone induces circadian gene expression of clock genes in H9c2 cardiomyoblasts. Heart Vessels 22 (4):: 254-60.
24. Bjarnason GA, Jordan RC, Wood PA, Li Q, Lincoln DW, et al. (2001) Circadian expression of clock genes in human oral mucosa and skin: association with specific cell-cycle phases. Am J Pathol 158: 1793-1801.
25. Boivin DB, James FO, Wu A, Cho-Park PF, Xiong H, et al. (2003) Circadian clock genes oscillate in human peripheral blood mononuclear cells. Blood 102: 4143-4145.
26. Kusanagi H, Mishima K, Satoh K, Echizenya M, Katoh T, et al. (2004) Similar profiles in human period1 gene expression in peripheral mononuclear and polymorphonuclear cells. Neurosci Lett 365: 124-127.
27. Otway DT, Mantele S, Bretschneider S, Wright J, Trayhurn P, et al. (2011) Rhythmic diurnal gene expression in human adipose tissue from individuals who are lean, overweight, and type 2 diabetic. Diabetes 60 (5):: 1577-1581.
28. Loboda A, Kraft WK, Fine B, Joseph J, Nebozhyn M, et al. (2009) Diurnal variation of the human adipose transcriptome and the link to metabolic disease. BMC Med Genomics 2: 7.
29. Ripperger JA, Jud C, Albrecht U, (2011) The daily rhythm of mice. FEBS Lett 585 (10):: 1384-92.
30. Teboul M, Barrat-Petit MA, Li XM, Claustrat B, Formento JL, et al. (2005) Atypical patterns of circadian clock gene expression in human peripheral blood mononuclear cells. J Mol Med (Berl) 83 (9):: 693-9.
31. Granda TG, Liu XH, Smaaland R, Cermakian N, Filipski E, et al. (2005) Circadian regulation of cell cycle and apoptosis proteins in mouse bone marrow and tumor. FASEB J 19 (2):: 304-6.
32. Després JP, Lemieux I, (2006) Abdominal obesity and metabolic syndrome. Nature 444: 881-887.
33. Balsalobre A, Marcacci L, Schibler U, (2000) Multiple signaling pathways elicit circadian gene expression in cultured Rat-1 fibroblasts. Curr Biol 10 (20):: 1291-4.
34. Nebzydoski SJ, Pozzo S, Nemec L, Rankin MK, Gressley TF, (2010) The effect of dexamethasone on clock gene mRNA levels in bovine neutrophils and lymphocytes. Vet Immunol Immunopathol 138 (3):: 183-92.