Role of apolipoprotein e in AB clearance promoting

Progress in Biochemistry and Biophysics

Volumn 39, Issue 8, 2012, Pages 829-830

  Yang, Hong Qi ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84870906901     PISSN: 10003282     EISSN: None     Source Type: Journal    
DOI: 10.3724/SP.J.1206.2012.00320     Document Type: Note

References (12)

1. Mawuenyega K G, Sigurdson W, Ovod V, el al. Decreased clearance of CNS beta-amyloid in Alzheimer's disease. Science, 2010, 330(6012): 1774
2. Cramer P E, Cirrito J R, Wesson D W, et al. ApoE-directed therapeutics rapidly clear β-amyloid and reverse deficits in AD mouse models. Science, 2012,335(6075): 1503-1506
3. Lefebvre P, Benomar Y, Staels B. Retinoid X receptors: common heterodimerization partners with distinct functions. Trends Endocrinol Metab, 2010,21(11): 676-683
4. Donkin J J, Stukas S, Hirsch-Reinshagen V, et al. ATP-binding cassette transporter Al mediates the beneficial effects of the liver X receptor agonist GW3965 on object recognition memory and amyloid burden in amyloid precursor protein/presenilin 1 mice. J Biol Chem, 2010,285(44): 34144-34154
5. Fitz N F, Cronican A, Pham T, et al. Liver X receptor agonist treatment ameliorates amyloid pathology and memory deficits caused by high-fat diet in APP23 mice. J Neurosci, 2010, 30(20): 6862-6872
6. Mandre Kar-Colucci S, Landreth G E. Nuclear receptors as therapeutic targets for Alzheimer's disease. Expert Opin Ther Targets, 2011,15(9): 1085-1097
7. Jiang Q, Lee C Y, Mandrekar S, et al. ApoE promotes the proteolytic degradation of Abeta. Neuron, 2008,58(5): 681-693 (Pubitemid 351778466)
8. Escribano L, Simon A M, Gimeno E, et al. Rosiglitazone rescues memory impairment in Alzheimer's transgenic mice: mechanisms involving a reduced amyloid and tau pathology. Neuropsychopharmacology, 2010,35(7): 1593-1604
9. Suon S, Zhao J, Villarreal S A, et al. Systemic treatment with liver X receptor agonists raises apolipoprotein E, cholesterol, and amyloid-ß peptides in the cerebral spinal fluid of rats. Mol Neurodegener, 2010, 5: 44
10. Nomoto M, Takeda Y, Uchida S, et al. Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity. MoI Brain, 2012,5: 8
11. Chételat G, Villemagne V L, Villain N, et al. Accelerated cortical atrophy in cognitively normal elderly with high β-amyloid deposition. Neurology, 2012, 78(7): 477-484
12. Villemagne V L, Pike K E, Chételat G, et al. Longitudinal assessment of Aß and cognition in aging and Alzheimer disease. Ann Neurol, 2011,69(1): 181-192