BRCA2 promoter hypermethylation in sporadic breast cancer

OMICS A Journal of Integrative Biology

Volumn 16, Issue 12, 2012, Pages 707-710

  Bosviel, Rémy ^a   Durif, Julie ^a   Guo, Jiaoli ^a   Mebrek, Mourad ^a   Kwiatkowski, Fabrice ^a   Bignon, Yves Jean ^a   Bernard Gallon, Dominique J ^a  

^a CENTRE JEAN PERRIN   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CYTOSINE; ESTROGEN RECEPTOR;

BODY MASS; BREAST CANCER; CARCINOGENESIS; CONFIDENCE INTERVAL; CPG ISLAND; DNA ISOLATION; GENE INACTIVATION; GENOTYPE; HUMAN; LETTER; OVARY CANCER; POLYMERASE CHAIN REACTION; POSTMENOPAUSE; PREDICTIVE VALUE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RECEIVER OPERATING CHARACTERISTIC; RELIABILITY; RISK FACTOR; SENSITIVITY AND SPECIFICITY; STATISTICAL ANALYSIS; TUMOR SUPPRESSOR GENE;

BRCA2 PROTEIN; BREAST NEOPLASMS; CPG ISLANDS; DNA METHYLATION; FEMALE; HUMANS; PROMOTER REGIONS, GENETIC; ROC CURVE;

EID: 84870904712     PISSN: 15362310     EISSN: 15578100     Source Type: Journal    
DOI: 10.1089/omi.2012.0060     Document Type: Letter

References (11)

1. Baylin SB, and Ohm JE. (2006). Epigenetic gene silencing in cancer. A mechanism for early oncogenic pathway addiction? Nat Rev Cancer 6, 107-116.
2. Bernard-Gallon DJ, De Latour MP, Rio PG, et al. (1999). Subcellular localization of BRCA1 protein in sporadic breast carcinoma with or without allelic loss of BRCA1 gene. Int J Oncol 14, 653-661.
3. Bieche I, Nogues C, and Lidereau R. (1999). Overexpression of BRCA2 gene in sporadic breast tumours. Oncogene 18, 5232- 5238.
4. Bosviel R, Garcia S, Lavediaux G, et al. (2012). BRCA1 promoter methylation in peripheral blood DNA was identified in sporadic breast cancer and controls. Cancer Epidemiol 36, e177- 182.
5. Bosviel R, Michard E, Lavediaux G, Kwiatkowski F, Bignon YJ, and Bernard-Gallon DJ. (2011). Peripheral blood DNA methylation detected in the BRCA1 or BRCA2 promoter for sporadic ovarian cancer patients and controls. Clin Chim Acta 412, 1472-1475.
6. Esteller M, Silva JM, Dominguez G, et al. (2000). Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors. J Natl Cancer Inst 92, 564-569.
7. Jemal A, Bray F, Center MM, Ferlay J, Ward E, and Forman D. (2011). Global cancer statistics. CA Cancer J Clin 61, 69-90.
8. Moelans CB, Verschuur-Maes AH, and Van Diest PJ. (2011). Frequent promoter hypermethylation of BRCA2, CDH13, MSH6, PAX5, PAX6 and WT1 in ductal carcinoma in situ and invasive breast cancer. J Pathol 225, 222-231.
9. Radpour R, Barekati Z, Kohler C, et al. (2011). Hypermethylation of tumor suppressor genes involved in critical regulatory pathways for developing a blood-based test in breast cancer. PLoS One 6, e16080.
10. Rahmatpanah FB, Carstens S, Hooshmand SI, et al. (2009). Large-scale analysis of DNA methylation in chronic lymphocytic leukemia. Epigenomics 1, 39-61.
11. Zeschnigk M, Bohringer S, Price EA, Onadim Z, Masshofer L, and Lohmann DR. (2004). A novel real-time PCR assay for quantitative analysis of methylated alleles (QAMA): Analysis of the retinoblastoma locus. Nucleic Acids Res 32, e125.