2-Hydroxypropyl-β-cyclodextrin-modified SLN of paclitaxel for overcoming p-glycoprotein function in multidrug-resistant breast cancer cells

Journal of Pharmacy and Pharmacology

Volumn 65, Issue 1, 2013, Pages 72-78

  Baek, Jong Suep ^a   Cho, Cheong Weon ^a  

^a Chungnam National University   (South Korea)

Author keywords

2 hydroxypropyl cyclodextrin; cellular uptake; paclitaxel; solid lipid nanoparticle; verapamil

Indexed keywords

2 HYDROXYPROPYL BETA CYCLODEXTRIN; MULTIDRUG RESISTANCE PROTEIN; PACLITAXEL; PHOSPHATIDYLCHOLINE; POLOXAMER; SOLID LIPID NANOPARTICLE; STEARIC ACID; VERAPAMIL;

ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG DOSAGE FORM COMPARISON; DRUG FORMULATION; DRUG UPTAKE; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; INCUBATION TIME; MULTIDRUG RESISTANCE; ORAL DRUG ADMINISTRATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; ULTRASOUND; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BETA-CYCLODEXTRINS; BIOLOGICAL TRANSPORT; BREAST NEOPLASMS; CALCIUM CHANNEL BLOCKERS; CELL SURVIVAL; CHEMISTRY, PHARMACEUTICAL; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; EXCIPIENTS; FEMALE; HUMANS; MCF-7 CELLS; NANOPARTICLES; NEOPLASM PROTEINS; P-GLYCOPROTEIN; PACLITAXEL; STEARIC ACIDS; SURFACE-ACTIVE AGENTS; ULTRASONICS; VERAPAMIL;

EID: 84870899494     PISSN: 00223573     EISSN: 20427158     Source Type: Journal    
DOI: 10.1111/j.2042-7158.2012.01578.x     Document Type: Article

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