Development of inflammation-induced hyperalgesia and allodynia is associated with the upregulation of extrasynaptic AMPA receptors in tonically firing lamina II dorsal horn neurons

Frontiers in Physiology

Volumn 3 OCT, Issue , 2012, Pages

  Kopach, Olga ^a   Viatchenko Karpinski, Viacheslav ^a   Belan, Pavel ^a   Voitenko, Nana ^a  

^a BOGOMOLETZ INSTITUTE OF PHYSIOLOGY   (Ukraine)

Author keywords

Allodynia; Development of inflammatory pain; Extrasynaptic AMPA receptors; Hyperalgesia; Substantia gelatinosa neurons

Indexed keywords

EID: 84870896204     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2012.00391     Document Type: Article

References (30)

1. adesnik, H., Nicoll, R. A., and England, P. M. (2005). Photoinactivation of native AMPA receptors reveals their real-time trafficking. Neuron 48, 977-985.
2. Allan, S. M., and Rothwell, N. J. (2001). Cytokines and acute neurodegeneration. Nat. Rev. Neurosci. 2, 734-744.
3. Arendt, K. L., Royo, M., Fernandez Monreal, M., Knafo, S., Petrok, C. N., Martens, J. R., et al. (2010). PIP3 controls synaptic function by maintaining AMPA receptor clustering at the postsynaptic membrane. Nat. Neurosci. 13, 36-44.
4. Borgdorff, A. J., and Choquet, D. (2002). Regulation of AMPA receptor lateral movements. Nature 417, 649-653.
5. Bredt, D. S., and Nicoll, R. A. (2003). AMPA receptor trafficking at excitatory synapses. Neuron 40, 361-379.
6. Choquet, D., and Triller, A. (2003). The role of receptor diffusion in the organization of the postsynaptic membrane. Nat. Rev. Neurosci. 4, 251-265.
7. Cognet, L., Groc, L., Lounis, B., and Choquet, D. (2006). Multiple routes for glutamate receptor trafficking: surface diffusion and membrane traffic cooperate to bring receptors to synapses. Sci. STKE 2006, e13.
8. Engelman, H. S., Allen, T. B. and MacDermott, A. B. (1999). The distribution of neurons expressing calcium-permeable AMPA receptors in the superficial laminae of the spinal cord dorsal horn. J. Neurosci. 19, 2081-2089.
9. Graham, B. A., Brichta, A. M., and Callister, R. J. (2004). In vivo responses of mouse superficial dorsal horn neurones to both current injection and peripheral cutaneous stimulation. J. Physiol. 561, 749-763.
10. Grudt, T. J., and Perl, E. R. (2002). Correlations between neuronal morphology and electrophysiological features in the rodent superficial dorsal horn. J. Physiol. 540, 189-207.
11. Guire, E. S., Oh, M. C., Soderling, T. R., and Derkach, V. A. (2008). Recruitment of calcium-permeable AMPA receptors during synaptic potentiation is regulated by CaM-kinase I. J. Neurosci. 28, 6000-6009.
12. Hargreaves, K., Dubner, R., Brown, F., Flores, C., and Joris, J. (1988). A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32, 77-88.
13. Hartmann, B., Ahmadi, S., Heppenstall, P. A., Lewin, G. R., Schott, C., Borchardt, T., et al. (2004). The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory pain. Neuron 44, 637-650.
14. He, K., Goel, A., Ciarkowski, C. E., Song, L., and Lee, H. K. (2011). Brain area specific regulation of synaptic AMPA receptors by phosphorylation. Commun. Integr. Biol. 4, 569-572.
15. Katano, T., Furue, H., Okuda-Ashitaka, E., Tagaya, M., Watanabe, M., Yoshimura, M., et al. (2008). Nethylmaleimide-sensitive fusion protein (NSF) is involved in central sensitization in the spinal cord through GluR2 subunit composition switch after inflammation. Eur. J. Neurosci. 27, 3161-3170.
16. Kopach, O., Kao, S. C., Petralia, R. S., Belan, P., Tao, Y. X., and Voitenko, N. (2011). Inflammation alters trafficking of extrasynaptic AMPA receptors in tonically firing lamina II neurons of the rat spinal dorsal horn. Pain 152, 912-923.
17. Kullmann, D. M. (2000). Spillover and synaptic cross talk mediated by glutamate and GABA in the mammalian brain. Prog. Brain Res. 125, 339-351.
18. Latremoliere, A., and Woolf, C. J. (2009). Central sensitization: a generator of pain hypersensitivity by central neural plasticity. J. Pain 10, 895-926.
19. Malinow, R., and Malenka, R. C. (2002). AMPA receptor trafficking and synaptic plasticity. Annu. Rev. Neurosci. 25, 103-126.
20. Park, J. S., Voitenko, N., Petralia, R. S., Guan, X., Xu, J. T., Steinberg, J. P., et al. (2009). Persistent inflammation induces GluR2 internalization via NMDA receptortriggered PKC activation in dorsal horn neurons. J. Neurosci. 29, 3206-3219.
21. Park, J. S., Yaster, M., Guan, X., Xu, J. T., Shih, M. H., Guan, Y., et al. (2008). Role of spinal cord alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors incomplete Freund's adjuvantinduced inflammatory pain. Mol. Pain 4, 67.
22. Santos, S. D., Carvalho, A. L., Caldeira, M. V., and Duarte, C. B. (2009). Regulation of AMPA receptors and synaptic plasticity. Neuroscience 58, 105-125.
23. Tao, Y. X. (2010). Dorsal horn alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor trafficking in inflammatory pain. Anesthesiology 112, 1259-1265.
24. 2+-permeable AMPA and reduced NR2B NMDA receptormediated neurotransmission at dorsal horn nociceptive synapses during inflammatory pain in the rat. J. Physiol. 586, 515-527.
25. Vizi, E. S., Fekete, A., Karoly, R., and Mike, A. (2010). Non-synaptic receptors and transporters involved in brain functions and targets of drug treatment. Br.J.Pharmacol. 160, 785-809.
26. 2+ transients in the presence of cyclothiazide in the rat substantia gelatinosa neurons. Cell Calcium 35, 461-469.
27. Wang, Y., Wu, J., Wu, Z., Lin, Q., Yue, Y., and Fang, L. (2010). Regulation of AMPA receptors in spinal nociception. Mol. Pain 6, 5.
28. Weng, H. R., Chen, J. H., and Cata, J. P. (2006). Inhibition of glutamate uptake in the spinal cord induces hyperalgesia and increased responses of spinal dorsal horn neurons to peripheral afferent stimulation. Neuroscience 138, 1351-1360.
29. Woolf, C. J., and Salter, M. W. (2000). Neuronal plasticity: increasing the gain in pain. Science 288, 1765-1769.
30. Zhang, B., Tao, F., Liaw, W. J., Bredt, D. S., Johns, R. A., and Tao, Y. X. (2003). Effect of knock down of spinal cord PSD-93/chapsin-110 on persistent pain induced by complete Freund's adjuvant and peripheral nerve injury. Pain 106, 187-196.