SCOPUS 정보 검색 플랫폼

Volumn 21, Issue 1, 2013, Pages 186-195

Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity

(9) Nag, S a Kettschau, G b Heinrich, T b Varrone, A a Lehmann, L b Gulyas, B a Thiele, A b Keller, E c Halldin, C a

a KAROLINSKA UNIVERSITY HOSPITAL (Sweden)

b BAYER PHARMA AG (Germany)

c SEMMELWEIS UNIVERSITY (Hungary)

Author keywords

Autoradiography; Fluorine 18; Human; Kinetics; Metabolites; Monkey; Monoamine oxidase (MAO); PET

Indexed keywords

1 FLUORO N,4 DIMETHYL N (PROP 2 YNYL)PENT 4 EN 2 AMINE; 1 FLUORO N,4 DIMETHYL N (PROP 2 YNYL)PENT 4 EN 2 AMINE F 18; 1 FLUORO N,4 DIMETHYL N (PROP 2 YNYL)PENTAN 2 AMINE; 1 FLUORO N,4 DIMETHYL N (PROP 2 YNYL)PENTAN 2 AMINE F 18; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME A; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; FLUORINE 18; N [1 FLUORO 3 (FURAN 2 YL)PROPAN 2 YL] N METHYLPROP 2 YN 1 AMINE; N [1 FLUORO 3 (FURAN 2 YL)PROPAN 2 YL] N METHYLPROP 2 YN 1 AMINE F 18; PROPARGYL AMINE DERIVATIVE; RADIOLIGAND; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOPSY; AUTORADIOGRAPHY; BRAIN CORTEX; BRAIN TISSUE; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; DRUG ACTIVITY; DRUG BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; DRUG UPTAKE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME INHIBITION; HUMAN; HUMAN TISSUE; IC 50; IN VITRO STUDY; MACACA FASCICULARIS; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; QUALITY CONTROL; RADIOACTIVITY; THALAMUS;

ANIMALS; AUTORADIOGRAPHY; BRAIN; FLUORINE RADIOISOTOPES; HUMANS; MACACA FASCICULARIS; MONOAMINE OXIDASE; PARGYLINE; POSITRON-EMISSION TOMOGRAPHY; PROPYLAMINES;

MACACA FASCICULARIS;

EID: 84870877680 PISSN: 09680896 EISSN: 14643391 Source Type: Journal
DOI: 10.1016/j.bmc.2012.10.050 Document Type: Article

Times cited : (13)

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