Association Analysis between SNPs in IL-28B Gene and the Progress of Hepatitis B Infection in Han Chinese

PLoS ONE

Volumn 7, Issue 12, 2012, Pages

  Chen, Jie ^a   Wang, Lanlan ^a   Li, Yi ^a   Cai, Bei ^a   Fu, Yang ^a   Liao, Yun ^a   Zhang, Junlong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOSINE; GENOMIC DNA; INTERLEUKIN 28B; THYMINE;

ADULT; ARTICLE; BLOOD SAMPLING; CHINESE; CONTROLLED STUDY; DNA ISOLATION; FEMALE; GENE AMPLIFICATION; GENE FREQUENCY; GENETIC ASSOCIATION; HEPATITIS B; HIGH RESOLUTION MELTING ANALYSIS; HUMAN; IL 28B GENE; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; POPULATION GENETICS; REAL TIME POLYMERASE CHAIN REACTION; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CARCINOMA, HEPATOCELLULAR; CASE-CONTROL STUDIES; DEMOGRAPHY; DISEASE PROGRESSION; ETHNIC GROUPS; FEMALE; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HEPATITIS B; HUMANS; INTERLEUKINS; LIVER NEOPLASMS; LOGISTIC MODELS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE;

HEPATITIS B VIRUS;

EID: 84870821202     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050787     Document Type: Article

References (15)

1. Chui SH, Chen JH, Szeto YT, Yam WC, (2011) Prevalence of hepatitis B genotype and viral basic core promoter and precore mutations among teenagers in Macao: relationship with hepatocellular carcinoma development. Br J Biomed Sci 68: 143-6.
2. Kim BK, Revill PA, Ahn SH, (2011) HBV genotypes: relevance to natural history, pathogenesis and treatment of chronic hepatitis B. Antivir Ther. 16: 1169-86.
3. Migita K, Sawakami-Kobayashi K, Maeda Y, Nakao K, Kondoh S, et al. (2009) Interleukin-18 promoter polymorphisms and the disease progression of Hepatitis B virus-related liver disease. Transl Res 153: 91-6.
4. Domagalski K, Tretyn A, Pawłowska M, Szczepanek J, Halota W, (2010) Action of type III IFNs and their roles in immune responses. Postepy Hig Med Dosw (Online) 64: 522-33.
5. Pearlman BL, (2011) The IL-28 genotype: how it will affect the care of patients with hepatitis C virus infection. Curr Gastroenterol Rep 13: 78-86.
6. Dumoutier L, Tounsi A, Michiels T, Sommereyns C, Kotenko SV, et al. (2004) Role of the interleukin (IL)-28 receptor tyrosine residues for antiviral and antiproliferative activity of IL-29/interferon-lambda 1: similarities with type I interferon signaling. J Biol Chem 279: 32269-74.
7. Martin MP, Qi Y, Goedert JJ, Hussain SK, Kirk GD, et al. (2010) IL28B polymorphism does not determine outcomes of hepatitis B virus or HIV infection.J Infect Dis. 202: 1749-53.
8. Fabris C, Falleti E, Cussigh A, Bitetto D, Fontanini E, et al. (2011) IL-28B rs12979860 C/T allele distribution in patients with liver cirrhosis: role in the course of chronic viral hepatitis and the development of HCC.J Hepatol. 54: 716-22.
9. Ren S, Lu J, Du X, Huang Y, Ma L, et al. (2012) Genetic variation in IL28B is associated with the development of hepatitis B-related hepatocellular carcinoma. Cancer Immunol Immunother 61: 1433-9.
10. Yan J, Xie W, Wang Q, Li Y, Feng X, et al. (2011) The optimal threshold: Baseline serum hepatitis B virus DNA and alanine transaminase levels can predict the 2-Year on-treatment virological response to lamivudine. Hepat Mon 11: 358-63.
11. Michielsen P, Ho E, (2011) Viral hepatitis B and hepatocellular carcinoma. Acta Gastroenterol Belg 74: 4-8.
12. Commins S, Steinke JW, Borish L, (2008) The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29. J Allergy Clin Immunol 121: 1108-11.
13. Thursz M, Yee L, Khakoo S, (2011) Understanding the host genetics of chronic hepatitis B and C. Semin Liver Dis. 31: 115-27.
14. Ruiz-Extremera A, Muñoz-Gámez JA, Salmerón-Ruiz MA, de Rueda PM, Quiles-Pérez R, et al. (2011) Genetic variation in interleukin 28B with respect to vertical transmission of hepatitis C virus and spontaneous clearance in HCV-infected children. Hepatology 53: 1830-8.
15. Shimomura S, Nishiguchi S, (2012) Anticarcinogenic impact of interferon therapy on the progression ofhepatocellular carcinoma in patients with chronic viral infection. Hepatol Res 42: 22-32.