Angiotensin II regulates the LARG/RhoA/MYPT1 axis in rat vascular smooth muscle in vitro

Acta Pharmacologica Sinica

Volumn 33, Issue 12, 2012, Pages 1502-1510

  Chiu, Wei Chiao ^a   Juang, Jyh Ming ^a,b   Chang, Shen Nan ^b   Wu, Cho Kai ^b   Tsai, Chia Ti ^b   Tseng, Yung Zu ^a,b   Chiang, Fu Tien ^a,b  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Angiotensin II; Aortic ring; Isometric contraction; LARg; Losartan; MYPT1; PD123319; RhoA; Val5 Ang II; Vascular smooth muscle

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN II; ANGIOTENSIN II [5 VALINE]; GUANINE NUCLEOTIDE EXCHANGE FACTOR; LEUKEMIA ASSOCIATED RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR; LOSARTAN; MESSENGER RNA; MYOSIN PHOSPHATASE TARGET SUBUNIT 1; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; FORCE TRANSDUCER; GENE EXPRESSION; GENE SILENCING; GENETIC TRANSFECTION; IN VITRO STUDY; MALE; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; RECORDER; SIGNAL TRANSDUCTION; UPREGULATION; VASCULAR RING; VASCULAR SMOOTH MUSCLE; WESTERN BLOTTING;

ANGIOTENSIN II; ANIMALS; AORTA, THORACIC; BLOTTING, WESTERN; CELLS, CULTURED; GENE EXPRESSION REGULATION; GUANINE NUCLEOTIDE EXCHANGE FACTORS; ISOMETRIC CONTRACTION; MALE; MUSCLE, SMOOTH, VASCULAR; PRIMARY CELL CULTURE; PROTEIN PHOSPHATASE 1; RATS; RATS, SPRAGUE-DAWLEY; REAL-TIME POLYMERASE CHAIN REACTION; RHOA GTP-BINDING PROTEIN; RNA, SMALL INTERFERING; UP-REGULATION;

EID: 84870802952     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.117     Document Type: Article

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