Identification of circulating microRNAs as diagnostic biomarkers for use in multiple myeloma

British Journal of Cancer

Volumn 107, Issue 12, 2012, Pages 1987-1996

  Jones, C I ^a   Zabolotskaya, M V ^a   King, A J ^a   Stewart, H J S ^a   Horne, G A ^a   Chevassut, T J ^a   Newbury, S F ^a  

^a UNIVERSITY OF SUSSEX   (United Kingdom)

Author keywords

biomarkers; cleaved tRNA; diagnostics; microRNAs; myeloma; serum miRNAs

Indexed keywords

MICRORNA; MICRORNA 1246; MICRORNA 1308; MICRORNA 181B; MICRORNA 1915; MICRORNA 1974; MICRORNA 451; MICRORNA 574 5P; MICRORNA 638; MICRORNA 720; MICRORNA 762; PARAPROTEIN; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; ARTICLE; BONE MARROW CELL; CANCER DIAGNOSIS; CANCER PATIENT; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENDER; GENE EXPRESSION PROFILING; HUMAN; MALE; MONOCLONAL IMMUNOGLOBULINEMIA; MULTIPLE MYELOMA; PLASMA CELL; PRECANCER; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN URINE LEVEL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICROARRAY ANALYSIS; MICRORNAS; MIDDLE AGED; MONOCLONAL GAMMOPATHY OF UNDETERMINED SIGNIFICANCE; MULTIPLE MYELOMA; PRECANCEROUS CONDITIONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TUMOR MARKERS, BIOLOGICAL;

EID: 84870798527     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2012.525     Document Type: Article

References (26)

1. Borek E, Baliga BS, Gehrke CW, Kuo CW, Belman S, Troll W, Waalkes TP(1977) High turnover rate of transfer RNA in tumor tissue. Cancer Res37: 3362-3366
2. Chen X, Liang H, Zhang J, Zen K, Zhang CY (2012) Secreted microRNAs:a new form of intercellular communication. Trends Cell Biol 22:125-132
3. Chikh A, Matin RN, Senatore V, Hufbauer M, Lavery D, Raimondi C,Ostano P, Mello-Grand M, Ghimenti C, Bahta A, Khalaf S, Akgul B, BraunKM, Chiorino G, Philpott MP, Harwood CA, Bergamaschi D (2011)iASPP/p63 autoregulatory feedback loop is required for the homeostasisof stratified epithelia. EMBO J 30: 4261-4273
4. Faraoni I, Antonetti FR, Cardone J, Bonmassar E (2009) miR-155 gene: atypical multifunctional microRNA. Biochim Biophys Acta 1792: 497-505
5. Git A, Dvinge H, Salmon-Divon M, Osborne M, Kutter C, Hadfield J,Bertone P, Caldas C (2010) Systematic comparison of microarrayprofiling, real-time PCR, and next-generation sequencing technologiesfor measuring differential microRNA expression. RNA 16: 991-1006
6. Heneghan HM, Miller N, Kelly R, Newell J, Kerin MJ (2010) SystemicmiRNA-195 differentiates breast cancer from other malignancies and is apotential biomarker for detecting noninvasive and early stage disease.Oncologist 15: 673-682
7. Hunter MP, Ismail N, Zhang X, Aguda BD, Lee EJ, Yu L, Xiao T, Schafer J,Lee ML, Schmittgen TD, Nana-Sinkam SP, Jarjoura D, Marsh CB (2008)Detection of microRNA expression in human peripheral blood microvesicles.PLoS One 3: e3694
8. Jones CI, Newbury SF (2010) Functions of microRNAs in Drosophiladevelopment. Biochem Soc Trans 38: 1137-1143
9. Kong YW, Ferland-McCollough D, Jackson TJ, Bushell M (2012) micro-RNAs in cancer management. Lancet Oncol 13: e249-e258
10. Kyle RA, Rajkumar SV (2008) Multiple myeloma. Blood 111: 2962-2972
11. Kyle RA, Remstein ED, Therneau TM, Dispenzieri A, Kurtin PJ, HodnefieldJM, Larson DR, Plevak MF, Jelinek DF, Fonseca R, Melton 3rd LJ,Rajkumar SV (2007) Clinical course and prognosis of smoldering(asymptomatic) multiple myeloma. N Engl J Med 356: 2582-2590
12. Lionetti M, Biasiolo M, Agnelli L, Todoerti K, Mosca L, Fabris S, Sales G,Deliliers GL, Bicciato S, Lombardi L, Bortoluzzi S, Neri A (2009)Identification of microRNA expression patterns and definition of amicroRNA/mRNA regulatory network in distinct molecular groups ofmultiple myeloma. Blood 114: e20-e26
13. Lodes MJ, Caraballo M, Suciu D, Munro S, Kumar A, Anderson B (2009)Detection of cancer with serum miRNAs on an oligonucleotidemicroarray. PLoS One 4: e6229
14. McKenna RW, Kyle RA, Kuehl WM, Grogan TM, Harris NL, Coupland RW(2008) Plasma cell neoplams. In WHO classification of tumours ofhaematopoietic and lymphoid tissues, Swerdlow SH, Campo E, Harris NL,Jaffe ES, Pileri SA, Stein H, Thiele J, Vardiman JW (eds) pp 200-203.International Agency for Research on Cancer: Lyon
15. Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, Peterson A, Noteboom J, O'Briant KC, Allen A, Lin DW,Urban N, Drescher CW, Knudsen BS, Stirewalt DL, Gentleman R,Vessella RL, Nelson PS, Martin DB, Tewari M (2008) CirculatingmicroRNAs as stable blood-based markers for cancer detection. ProcNatl Acad Sci USA 105: 10513-10518
16. Neal CS, Michael MZ, Pimlott LK, Yong TY, Li JY, Gleadle JM (2011)Circulating microRNA expression is reduced in chronic kidney disease.Nephrol Dial Transplant 26: 3794-3802
17. Pichiorri F, Suh SS, Ladetto M, Kuehl M, Palumbo T, Drandi D, Taccioli C,Zanesi N, Alder H, Hagan JP, Munker R, Volinia S, Boccadoro M, GarzonR, Palumbo A, Aqeilan RI, Croce CM (2008) MicroRNAs regulate criticalgenes associated with multiple myeloma pathogenesis. Proc Natl Acad SciUSA 105: 12885-12890
18. Reid G, Kirschner MB, van Zandwijk N (2011) Circulating microRNAs:association with disease and potential use as biomarkers. Crit Rev OncolHematol 80: 193-208
19. Roccaro AM, Sacco A, Thompson B, Leleu X, Azab AK, Azab F, Runnels J,Jia X, Ngo HT, Melhem MR, Lin CP, Ribatti D, Rollins BJ, Witzig TE,Anderson KC, Ghobrial IM (2009) MicroRNAs 15a and 16 regulate tumorproliferation in multiple myeloma. Blood 113: 6669-6680
20. Roth C, Rack B, Muller V, Janni W, Pantel K, Schwarzenbach H (2010)Circulating microRNAs as blood-based markers for patients withprimary and metastatic breast cancer. Breast Cancer Res 12: R90
21. Speer J, Gehrke CW, Kuo KC, Waalkes TP, Borek E (1979) tRNAbreakdown products as markers for cancer. Cancer 44: 2120-2123
22. Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J,Vardiman JW (eds) (2008) WHO classification of tumours of Haematopoieticand lymphoid tissues. I.A.R.C.: Lyon
23. Terpos E, Rahemtulla A (2005) Myeloma. In Postgraduate Haematology,Hoffbrand AV, Catovsky D, Tuddenham EGD (eds) 5th edn pp 681-702.Blackwell: Oxford
24. Walker BA, Wardell CP, Melchor L, Hulkki S, Potter NE, Johnson DC,Fenwick K, Kozarewa I, Gonzalez D, Lord CJ, Ashworth A, Davies FE,Morgan GJ (2012) Intraclonal heterogeneity and distinct molecularmechanisms characterize the development of t(4;14) and t(11;14)myeloma. Blood 120: 1077-1086
25. Zen K, Zhang C-Y (2010) Circulating MicroRNAs: a novel class of biomarkers todiagnose and monitor human cancers. MED RES REV 32: 326-348
26. Zhu W, Qin W, Atasoy U, Sauter E (2009) Circulating microRNAs in breastcancer and healthy subjects. BMC Res Notes 2: 89