A systematic review on prognostic indicators of acute on chronic liver failure and their predictive value for mortality

Liver International

Volumn 33, Issue 1, 2013, Pages 40-52

  Wlodzimirow, Kama A ^a   Eslami, Saeid ^a   Abu Hanna, Ameen ^a   Nieuwoudt, Martin ^b   Chamuleau, Robert A F M ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b STELLENBOSCH UNIVERSITY   (South Africa)

Author keywords

Acute liver failure; Acute on chronic liver failure; Bio markers; Fulminant hepatic failure; Liver failure; Predictors; Prognosis; Prognostic indicators

Indexed keywords

ALBUMIN; ANTIVIRUS AGENT; BILIRUBIN; CREATININE; DNA; HEPATITIS B(E) ANTIGEN; LAMIVUDINE;

ACUTE ON CHRONIC LIVER FAILURE; ALBUMIN BLOOD LEVEL; ANTIVIRAL THERAPY; BILIRUBIN BLOOD LEVEL; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE SEVERITY; HEMODYNAMICS; HEPATITIS B VIRUS; HUMAN; HYPERBILIRUBINEMIA; JAUNDICE; LIVER FUNCTION; MORTALITY; OBSERVATIONAL STUDY; PLASMAPHERESIS; PREDICTIVE VALUE; PROGNOSIS; RENAL REPLACEMENT THERAPY; REVIEW; SCORING SYSTEM; SYSTEMATIC REVIEW;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CHILD; DISEASE PROGRESSION; EARLY DIAGNOSIS; END STAGE LIVER DISEASE; FEMALE; HEALTH STATUS INDICATORS; HUMANS; LIVER FAILURE, ACUTE; LIVER FUNCTION TESTS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROGNOSIS; RISK ASSESSMENT; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TERMINOLOGY AS TOPIC; YOUNG ADULT;

EID: 84870775272     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/j.1478-3231.2012.02790.x     Document Type: Review

References (22)

1. Katoonizadeh A, Laleman W, Verslype C, et al. Early features of acute-on-chronic alcoholic liver failure: a prospective cohort study. Gut 2010; 59: 1561-9.
2. Sarin SK, Kumar A, Almeida JA, et al. Acute-on-chronic liver failure: consensus recommendations of the Asian Pacific Association for the study of the liver (APASL). Hepatol Int 2009; 3: 269-82.
3. Olson JC, Kamath PS. Acute-on-chronic liver failure: concept, natural history, and prognosis. Curr Opin Crit Care 2011; 17: 165-9.
4. Zheng MH, Shi KQ, Fan YC, et al. A model to determine 3-month mortality risk in patients with acute-on-chronic hepatitis B liver failure. Clin Gastroenterol Hepatol 2011; 9: 351-6.
5. Yu JW, Wang GQ, Li SC. Prediction of the prognosis in patients with acute-on-chronic hepatitis using the MELD scoring system. J Gastroenterol Hepatol 2006; 21: 1519-24.
6. Sun L-J, Yu J-W, Zhao Y-H, Kang P, Li S-C. Influential factors of prognosis in lamivudine treatment for patients with acute-on-chronic hepatitis B liver failure. J Gastroenterol Hepatol 2010; 25: 583-90.
7. Karvellas CJ, Pink F, McPhail M, et al. Bacteremia, acute physiology and chronic health evaluation II and modified end stage liver disease are independent predictors of mortality in critically ill nontransplanted patients with acute on chronic liver failure. Crit Care Med 2010; 38: 121-6.
8. Jalan R, Williams R. Acute-on-chronic liver failure: pathophysiological basis of therapeutic options. Blood Purif 2002; 20: 252-61.
9. Krishna YR, Saraswat VA, Das K, et al. Clinical features and predictors of outcome in acute hepatitis A and hepatitis E virus hepatitis on cirrhosis. Liver Int 2009; 29: 392-8.
10. Garg H, Kumar A, Garg V, et al. Clinical profile and predictors of mortality in patients of acute-on-chronic liver failure. Dig Liver Dis 2012; 44: 166-71.
11. Garg H, Sarin SK, Kumar M, et al. Tenofovir improves the outcome in patients with spontaneous reactivation of hepatitis B presenting as acute-on-chronic liver failure. Hepatology 2011; 53: 774-80.
12. Huang K, Hu JH, Wang HF, et al. Survival and prognostic factors in hepatitis B virus-related acute-on-chronic liver failure. World J Gastroenterol 2011; 17: 3448-52.
13. Meng QH, Hou W, Yu HW, et al. Resting energy expenditure and substrate metabolism in patients with acute-on-chronic hepatitis B liver failure. J Clin Gastroenterol 2011; 45: 456-61.
14. Rastogi A, Kumar A, Sakhuja P, et al. Liver histology as predictor of outcome in patients with acute-on-chronic liver failure (ACLF). Virchows Arch 2011; 459: 121-7.
15. Zhai S, Zhang L, Dang S, et al. The ratio of Th-17 to Treg cells is associated with survival of patients with acute-on-chronic hepatitis B liver failure. Viral Immunol 2011; 24: 303-10.
16. Zhihui X, Xiaoqiang R, Yan L, et al. Association of hepatitis B virus mutations in basal core promoter and precore regions with severity of liver disease: an investigation of 793 Chinese patients with mild and severe chronic hepatitis B and acute-on-chronic liver failure. J Gastroenterol 2011; 46: 391-400.
17. Han T, Liu Y, Liu H, et al. Serum thymosin beta4 levels in patients with hepatitis B virus-related liver failure. World J Gastroenterol 2010; 16: 625-30.
18. Novelli G, Rossi M, Ferretti G, et al. Predictive parameters after molecular absorbent recirculating system treatment integrated with model for end stage liver disease model in patients with acute-on-chronic liver failure. Transplant Proc 2010; 42: 1182-7.
19. Shi F, Zhang JY, Zeng Z, Tien P, Wang FS. Skewed ratios between CD3(+) T cells and monocytes are associated with poor prognosis in patients with HBV-related acute-on-chronic liver failure. Biochem Biophys Res Commun 2010; 402: 30-6.
20. Sun Q-F, Ding J-G, Xu D-Z, et al. Prediction of the prognosis of patients with acute-on-chronic hepatitis B liver failure using the model for end-stage liver disease scoring system and a novel logistic regression model. J Viral Hepatitis 2009; 16: 464-70.
21. Wang Z-X, Yan L-N, Wang W-T, Xu M-Q, Yang J-Y. Impact of pretransplant MELD score on posttransplant outcome in orthotopic liver transplantation for patients with acute-on-chronic hepatitis B liver failure. Transpl Proc 2007; 39: 1501-4.
22. Yang S-S, Cheng K-S, Lai Y-C, et al. Decreasing serum alpha-fetoprotein levels in predicting poor prognosis of acute hepatic failure in patients with chronic hepatitis B. J Gastroenterol 2002; 37: 626-32.