메뉴 건너뛰기




Volumn 7, Issue 12, 2012, Pages

Vitamin B-12 Status during Pregnancy and Child's IQ at Age 8: A Mendelian Randomization Study in the Avon Longitudinal Study of Parents and Children

Author keywords

[No Author keywords available]

Indexed keywords

CYANOCOBALAMIN; FUT2 PROTEIN; PROTEIN; TCN2 PROTEIN; UNCLASSIFIED DRUG;

EID: 84870772936     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0051084     Document Type: Article
Times cited : (28)

References (41)
  • 1
    • 49249114759 scopus 로고    scopus 로고
    • Micronutrient status, cognition and behavioral problems in childhood
    • Benton D, (2008) Micronutrient status, cognition and behavioral problems in childhood. Eur J Nutr 47Suppl 3: 38-50.
    • (2008) Eur J Nutr , vol.47 , pp. 38-50
    • Benton, D.1
  • 2
    • 27744508822 scopus 로고    scopus 로고
    • Homocysteine, folic acid and vitamin B12 in relation to pre- and postnatal health aspects
    • Obeid R, Herrmann W, (2005) Homocysteine, folic acid and vitamin B12 in relation to pre- and postnatal health aspects. Clin Chem Lab Med 43: 1052-7.
    • (2005) Clin Chem Lab Med , vol.43 , pp. 1052-1057
    • Obeid, R.1    Herrmann, W.2
  • 4
    • 37049031478 scopus 로고    scopus 로고
    • Holotranscobalamin remains unchanged during pregnancy. Longitudinal changes of cobalamins and their binding proteins during pregnancy and postpartum
    • Morkbak AL, Hvas AM, Milman N, Nexo E, (2007) Holotranscobalamin remains unchanged during pregnancy. Longitudinal changes of cobalamins and their binding proteins during pregnancy and postpartum. Haematologica 92: 1711-2.
    • (2007) Haematologica , vol.92 , pp. 1711-1712
    • Morkbak, A.L.1    Hvas, A.M.2    Milman, N.3    Nexo, E.4
  • 5
    • 34548094288 scopus 로고    scopus 로고
    • Longitudinal study of the effect of pregnancy on maternal and fetal cobalamin status in healthy women and their offspring
    • Murphy MM, Molloy AM, Ueland PM, Fernandez-Ballart JD, Schneede J, et al. (2007) Longitudinal study of the effect of pregnancy on maternal and fetal cobalamin status in healthy women and their offspring. J Nutr 137: 1863-7.
    • (2007) J Nutr , vol.137 , pp. 1863-1867
    • Murphy, M.M.1    Molloy, A.M.2    Ueland, P.M.3    Fernandez-Ballart, J.D.4    Schneede, J.5
  • 6
    • 58649104481 scopus 로고    scopus 로고
    • Vitamin B12 status of pregnant Indian women and cognitive function in their 9-year-old children
    • Bhate V, Deshpande S, Bhat D, Joshi N, Ladkat R, et al. (2008) Vitamin B12 status of pregnant Indian women and cognitive function in their 9-year-old children. Food Nutr Bull 29: 249-254.
    • (2008) Food Nutr Bull , vol.29 , pp. 249-254
    • Bhate, V.1    Deshpande, S.2    Bhat, D.3    Joshi, N.4    Ladkat, R.5
  • 7
    • 65349137788 scopus 로고    scopus 로고
    • Maternal MTHFR 677C>T genotype and dietary intake of folate and vitamin B(12): their impact on child neurodevelopment
    • del Río Garcia C, Torres-Sánchez L, Chen J, Schnaas L, Hernández C, et al. (2009) Maternal MTHFR 677C>T genotype and dietary intake of folate and vitamin B(12): their impact on child neurodevelopment. Nutr Neurosci 12: 13-20.
    • (2009) Nutr Neurosci , vol.12 , pp. 13-20
    • del Río Garcia, C.1    Torres-Sánchez, L.2    Chen, J.3    Schnaas, L.4    Hernández, C.5
  • 8
    • 77951477003 scopus 로고    scopus 로고
    • Higher maternal plasma folate but not vitamin B-12 concentrations during pregnancy are associated with better cognitive function scores in 9- to 10- year-old children in South India
    • Veena SR, Krishnaveni GV, Srinivasan K, Wills AK, Muthayya S, et al. (2010) Higher maternal plasma folate but not vitamin B-12 concentrations during pregnancy are associated with better cognitive function scores in 9- to 10- year-old children in South India. J Nutr 140: 1014-22.
    • (2010) J Nutr , vol.140 , pp. 1014-1022
    • Veena, S.R.1    Krishnaveni, G.V.2    Srinivasan, K.3    Wills, A.K.4    Muthayya, S.5
  • 9
    • 0037322022 scopus 로고    scopus 로고
    • "Mendelian randomization": can genetic epidemiology contribute to understanding environmental determinants of disease?
    • Davey Smith G, Ebrahim S, (2003) "Mendelian randomization": can genetic epidemiology contribute to understanding environmental determinants of disease? Int J Epidemiol 32: 1-22.
    • (2003) Int J Epidemiol , vol.32 , pp. 1-22
    • Davey Smith, G.1    Ebrahim, S.2
  • 10
    • 40849083720 scopus 로고    scopus 로고
    • Mendelian randomization: using genes as instruments for making causal inferences in epidemiology
    • Lawlor DA, Harbord RM, Sterne JAC, Timpson N, Davey Smith G, (2008) Mendelian randomization: using genes as instruments for making causal inferences in epidemiology. Stat Med 27: 1133-63.
    • (2008) Stat Med , vol.27 , pp. 1133-1163
    • Lawlor, D.A.1    Harbord, R.M.2    Sterne, J.A.C.3    Timpson, N.4    Davey Smith, G.5
  • 11
    • 52949095721 scopus 로고    scopus 로고
    • Common variants of FUT2 are associated with plasma vitamin B12 levels
    • Hazra A, Kraft P, Selhub J, Giovannucci EL, Thomas G, et al. (2008) Common variants of FUT2 are associated with plasma vitamin B12 levels. Nat Genet 40: 1160-2.
    • (2008) Nat Genet , vol.40 , pp. 1160-1162
    • Hazra, A.1    Kraft, P.2    Selhub, J.3    Giovannucci, E.L.4    Thomas, G.5
  • 12
    • 64149102559 scopus 로고    scopus 로고
    • Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations
    • Tanaka T, Scheet P, Giusti B, Bandinelli S, Piras MG, et al. (2009) Genome-wide association study of vitamin B6, vitamin B12, folate, and homocysteine blood concentrations. Am J Hum Genet 84: 477-82.
    • (2009) Am J Hum Genet , vol.84 , pp. 477-482
    • Tanaka, T.1    Scheet, P.2    Giusti, B.3    Bandinelli, S.4    Piras, M.G.5
  • 13
    • 77951207405 scopus 로고    scopus 로고
    • The TCN2 776C>G polymorphism correlates with vitamin B12 cellular delivery in healthy adult populations
    • Castro R, Barroso M, Rocha M, Esse R, Ramos R, et al. (2010) The TCN2 776C>G polymorphism correlates with vitamin B12 cellular delivery in healthy adult populations. Clin Biochem 43: 645-9.
    • (2010) Clin Biochem , vol.43 , pp. 645-649
    • Castro, R.1    Barroso, M.2    Rocha, M.3    Esse, R.4    Ramos, R.5
  • 14
    • 0036045429 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects
    • Afman LA, Lievers KJA, van der Put NMJ, Trijbels FJM, Blom HJ, (2002) Single nucleotide polymorphisms in the transcobalamin gene: relationship with transcobalamin concentrations and risk for neural tube defects. Eur J Hum Genet 10: 433-8.
    • (2002) Eur J Hum Genet , vol.10 , pp. 433-438
    • Afman, L.A.1    Lievers, K.J.A.2    van der Put, N.M.J.3    Trijbels, F.J.M.4    Blom, H.J.5
  • 15
    • 0036721305 scopus 로고    scopus 로고
    • Polymorphisms in the transcobalamin gene: association with plasma homocysteine in healthy individuals and vascular disease patients
    • Lievers KJA, Afman LA, Kluijtmans LAJ, Boers GHJ, Verhoef P, et al. (2002) Polymorphisms in the transcobalamin gene: association with plasma homocysteine in healthy individuals and vascular disease patients. Clin Chem 48: 1383-9.
    • (2002) Clin Chem , vol.48 , pp. 1383-1389
    • Lievers, K.J.A.1    Afman, L.A.2    Kluijtmans, L.A.J.3    Boers, G.H.J.4    Verhoef, P.5
  • 16
    • 81055134843 scopus 로고    scopus 로고
    • Transcobalamin polymorphism 67A->G, but not 776C->G, affects serum holotranscobalamin in a cohort of healthy middle-aged men and women
    • Riedel BM, Molloy AM, Meyer K, Fredriksen A, Ulvik A, et al. (2011) Transcobalamin polymorphism 67A->G, but not 776C->G, affects serum holotranscobalamin in a cohort of healthy middle-aged men and women. J Nutr 141: 1784-90.
    • (2011) J Nutr , vol.141 , pp. 1784-1790
    • Riedel, B.M.1    Molloy, A.M.2    Meyer, K.3    Fredriksen, A.4    Ulvik, A.5
  • 17
    • 84865132933 scopus 로고    scopus 로고
    • Cohort Profile: The "Children of the 90s"-the index offspring of the Avon Longitudinal Study of Parents and Children
    • Boyd A, Golding J, Macleod J, Lawlor D A, Fraser A, et al. (2012) Cohort Profile: The "Children of the 90s"-the index offspring of the Avon Longitudinal Study of Parents and Children. Int J Epidemiol: 1-17.
    • (2012) Int J Epidemiol , pp. 1-17
    • Boyd, A.1    Golding, J.2    Macleod, J.3    Lawlor, D.A.4    Fraser, A.5
  • 18
    • 84865339386 scopus 로고    scopus 로고
    • Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort
    • Fraser A, Macdonald-Wallis C, Tilling K, Boyd A, Golding J, et al. (2012) Cohort Profile: The Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort. Int J Epidemiol: 1-14.
    • (2012) Int J Epidemiol , pp. 1-14
    • Fraser, A.1    Macdonald-Wallis, C.2    Tilling, K.3    Boyd, A.4    Golding, J.5
  • 19
    • 34547670922 scopus 로고    scopus 로고
    • A United Kingdom population-based study of intellectual capacities in children with and without soiling, daytime wetting, and bed-wetting
    • doi:10.1542/peds.2006-2891
    • Joinson C, Heron J, Butler R, Von Gontard A, Butler U, et al. (2007) A United Kingdom population-based study of intellectual capacities in children with and without soiling, daytime wetting, and bed-wetting. Pediatrics 120: e308-16 doi:10.1542/peds.2006-2891.
    • (2007) Pediatrics , vol.120
    • Joinson, C.1    Heron, J.2    Butler, R.3    von Gontard, A.4    Butler, U.5
  • 21
    • 0023236013 scopus 로고
    • Microbiological assay for vitamin B12 with use of a colistin-sulfate-resistant organism
    • Kelleher BP, Walshe KG, Scott JM, OBroin SD, (1987) Microbiological assay for vitamin B12 with use of a colistin-sulfate-resistant organism. Clin Chem 33: 52-54.
    • (1987) Clin Chem , vol.33 , pp. 52-54
    • Kelleher, B.P.1    Walshe, K.G.2    Scott, J.M.3    OBroin, S.D.4
  • 22
    • 29744454316 scopus 로고    scopus 로고
    • Holotranscobalamin and total transcobalamin in human plasma: determination, determinants, and reference values in healthy adults
    • Refsum H, Johnston C, Guttormsen AB, Nexo E, (2006) Holotranscobalamin and total transcobalamin in human plasma: determination, determinants, and reference values in healthy adults. Clin Chem 52: 129-37.
    • (2006) Clin Chem , vol.52 , pp. 129-137
    • Refsum, H.1    Johnston, C.2    Guttormsen, A.B.3    Nexo, E.4
  • 23
    • 0031921777 scopus 로고    scopus 로고
    • Diet during pregnancy in a population of pregnant women in South West England. ALSPAC Study Team. Avon Longitudinal Study of Pregnancy and Childhood
    • Rogers I, Emmett P, (1998) Diet during pregnancy in a population of pregnant women in South West England. ALSPAC Study Team. Avon Longitudinal Study of Pregnancy and Childhood. Eur J Clin Nutr 52: 246-50.
    • (1998) Eur J Clin Nutr , vol.52 , pp. 246-250
    • Rogers, I.1    Emmett, P.2
  • 25
    • 0033812249 scopus 로고    scopus 로고
    • A new human genetic resource: a DNA bank established as part of the Avon Longitudinal Study of Pregnancy and Childhood (ALSPAC)
    • Jones RW, Ring S, Tyfield L, Hamvas R, Simmons H, et al. (2000) A new human genetic resource: a DNA bank established as part of the Avon Longitudinal Study of Pregnancy and Childhood (ALSPAC). Eur J Hum Genet 8: 653-660.
    • (2000) Eur J Hum Genet , vol.8 , pp. 653-660
    • Jones, R.W.1    Ring, S.2    Tyfield, L.3    Hamvas, R.4    Simmons, H.5
  • 26
    • 78649508578 scopus 로고    scopus 로고
    • MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes
    • Li Y, Willer CJ, Ding J, Scheet P, Abecasis GR, (2010) MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes. Genet Epidemiol 34: 816-34.
    • (2010) Genet Epidemiol , vol.34 , pp. 816-834
    • Li, Y.1    Willer, C.J.2    Ding, J.3    Scheet, P.4    Abecasis, G.R.5
  • 27
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, et al. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38: 904-9.
    • (2006) Nat Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5
  • 28
    • 34548292504 scopus 로고    scopus 로고
    • PLINK: a tool set for whole-genome association and population-based linkage analyses
    • Purcell S, Neale B, Todd-Brown K, Thomas L, Ferreira MAR, et al. (2007) PLINK: a tool set for whole-genome association and population-based linkage analyses. Am J Hum Genet 81: 559-75.
    • (2007) Am J Hum Genet , vol.81 , pp. 559-575
    • Purcell, S.1    Neale, B.2    Todd-Brown, K.3    Thomas, L.4    Ferreira, M.A.R.5
  • 29
    • 0035865701 scopus 로고    scopus 로고
    • Transcobalamin codon 259 polymorphism in HT-29 and Caco-2 cells and in Caucasians: relation to transcobalamin and homocysteine concentration in blood
    • Namour F, (2001) Transcobalamin codon 259 polymorphism in HT-29 and Caco-2 cells and in Caucasians: relation to transcobalamin and homocysteine concentration in blood. Blood 97: 1092-1098.
    • (2001) Blood , vol.97 , pp. 1092-1098
    • Namour, F.1
  • 30
    • 79951915082 scopus 로고    scopus 로고
    • A single nucleotide polymorphism in transcobalamin II (I5V) induces structural changes in the protein as revealed by molecular modeling studies
    • Silla Y, Chandamouli B, Maiti S, Sengupta S, (2011) A single nucleotide polymorphism in transcobalamin II (I5V) induces structural changes in the protein as revealed by molecular modeling studies. Biochemistry 50: 1396-402.
    • (2011) Biochemistry , vol.50 , pp. 1396-1402
    • Silla, Y.1    Chandamouli, B.2    Maiti, S.3    Sengupta, S.4
  • 32
    • 77955398591 scopus 로고    scopus 로고
    • Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease
    • McGovern DPB, Jones MR, Taylor KD, Marciante K, Yan X, et al. (2010) Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease. Hum Mol Genet 19: 3468-76.
    • (2010) Hum Mol Genet , vol.19 , pp. 3468-3476
    • McGovern, D.P.B.1    Jones, M.R.2    Taylor, K.D.3    Marciante, K.4    Yan, X.5
  • 33
    • 76649142715 scopus 로고    scopus 로고
    • Helicobacter pylori and micronutrients
    • Akcam M, (2010) Helicobacter pylori and micronutrients. Indian Pediatr 47: 119-26.
    • (2010) Indian Pediatr , vol.47 , pp. 119-126
    • Akcam, M.1
  • 35
    • 77249098764 scopus 로고    scopus 로고
    • Maternal folate and cobalamin status predicts vitamin status in newborns and 6-month-old infants
    • Hay G, Clausen T, Whitelaw A, Trygg K, Johnston C, et al. (2010) Maternal folate and cobalamin status predicts vitamin status in newborns and 6-month-old infants. J Nutr 140: 557-64.
    • (2010) J Nutr , vol.140 , pp. 557-564
    • Hay, G.1    Clausen, T.2    Whitelaw, A.3    Trygg, K.4    Johnston, C.5
  • 36
    • 48249148190 scopus 로고    scopus 로고
    • Effects of vitamin B12 and folate deficiency on brain development in children
    • Black MM, (2008) Effects of vitamin B12 and folate deficiency on brain development in children. Food Nutr Bull 29: S126-31.
    • (2008) Food Nutr Bull , vol.29
    • Black, M.M.1
  • 37
    • 0030883125 scopus 로고    scopus 로고
    • Persistence of neurological damage induced by dietary vitamin B-12 deficiency in infancy
    • von Schenck U, Bender-Götze C, Koletzko B, (1997) Persistence of neurological damage induced by dietary vitamin B-12 deficiency in infancy. Arch Dis Child 77: 137-9.
    • (1997) Arch Dis Child , vol.77 , pp. 137-139
    • von Schenck, U.1    Bender-Götze, C.2    Koletzko, B.3
  • 38
    • 63649101216 scopus 로고    scopus 로고
    • Dietary sources of vitamin B-12 and their association with plasma vitamin B-12 concentrations in the general population: the Hordaland Homocysteine Study
    • Vogiatzoglou A, Smith AD, Nurk E, Berstad P, Drevon CA, et al. (2009) Dietary sources of vitamin B-12 and their association with plasma vitamin B-12 concentrations in the general population: the Hordaland Homocysteine Study. Am J Clin Nutr 89: 1078-87.
    • (2009) Am J Clin Nutr , vol.89 , pp. 1078-1087
    • Vogiatzoglou, A.1    Smith, A.D.2    Nurk, E.3    Berstad, P.4    Drevon, C.A.5
  • 39
    • 77951678488 scopus 로고    scopus 로고
    • Mendelian randomization: use of genetics to enable causal inference in observational studies
    • Verduijn M, Siegerink B, Jager KJ, Zoccali C, Dekker FW, (2010) Mendelian randomization: use of genetics to enable causal inference in observational studies. Nephrol Dial Transplant 25: 1394-8.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 1394-1398
    • Verduijn, M.1    Siegerink, B.2    Jager, K.J.3    Zoccali, C.4    Dekker, F.W.5
  • 40
    • 38949127024 scopus 로고    scopus 로고
    • Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology?
    • Ebrahim S, Davey Smith G, (2008) Mendelian randomization: can genetic epidemiology help redress the failures of observational epidemiology? Hum Genet 123: 15-33.
    • (2008) Hum Genet , vol.123 , pp. 15-33
    • Ebrahim, S.1    Davey Smith, G.2
  • 41
    • 38049023073 scopus 로고    scopus 로고
    • Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology
    • Davey Smith G, Lawlor DA, Harbord R, Timpson N, Day I,et al. Clustered environments and randomized genes: a fundamental distinction between conventional and genetic epidemiology. PLoS Med 4: e352.
    • PLoS Med , vol.4
    • Davey Smith, G.1    Lawlor, D.A.2    Harbord, R.3    Timpson, N.4    Day, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.