Synthesis and pharmacological screening of some new azetidinone derivatives

International Journal of Pharmacy and Pharmaceutical Sciences

Volumn 4, Issue SUPPL. 5, 2012, Pages 464-467

  Pawar, Pratap Y ^a   Kalure, Swati U ^a   Kulkarni, Reshma B ^a  

^a Padmashri Dr Vithalrao Vikhe Patil Foundation's College of Pharmacy   (India)

Author keywords

Anticonvulsant activities; Aromatic aldehyde; Azetidinones; P amino benzoic acid; Schiff Base

Indexed keywords

ANTICONVULSIVE AGENT; AZETIDINONE DERIVATIVE; DIAZEPAM;

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ANTICONVULSANT THERAPY; ARTICLE; CONVULSION; CYCLOADDITION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; INFRARED SPECTROSCOPY; NEUROTOXICITY; NONHUMAN; POLYMERIZATION; PROTON NUCLEAR MAGNETIC RESONANCE; THIN LAYER CHROMATOGRAPHY;

EID: 84870752683     PISSN: None     EISSN: 09751491     Source Type: Journal    
DOI: None     Document Type: Article

References (16)

1. Ashok kumar et al, Synthesis of N-(substituted) benzylidine and benzyl p-amino benzoic acid, Indian drug, October 2009, 46(10), 803.
2. Ilango K. and Arun kumar S., Synthesis and antitubercular activities of Some Novel Trihydroxy Benzamido Azetidin-2-one Derivatives, Tropical Journal of Pharmaceutical Research, April 2011, 10(2), 219-229.
3. Monika Konaklieva, Balbin Plotkin and Terena Herbert, β-Lactams as Neuroprotective Agents, Anti-Infective Agents in Medicinal Chemistry, 2009, 8, 28-30.
4. Navin B. Patel et al, Synthesis and antimicrobial activity of Schiff base and 2-azetidinones derived from quinazoline-4(3H)-one, Arabian Journal of Chemistry, 2011, 4, 403-411.
5. Ramalakshmi N., Vijayakumar, Ilango K. and Arunkumar S., Synthesis and biological evaluation of 4-aryl-3-chloro-1-nicotinamido-2-azetidinones as Potential anticonvulsant and Antimycobacterial agents, International Journal of Chemical Science: 2008, 6(3), 1213-1222.
6. Rajiv Dua and S.K. Srivastav, Synthesis, Charactrization and antimicrobial activity of 2-[2′-{4-substituted-aryl-3-chloro-2-oxaazetidine}-Acetyl-amino-mercapto]-5-methyl-1,3,4-thiadiazoles, International Journal of Pharma and Bio-science, 2010, 1(2), 1-7.
7. Patel R.B. et al, Synthesis of pyrimidine based azetidinones and Thiazolidinones: Antimicrobial and Antitubercular agent, Indian Journal of Chemistry, March 2006, 45B, 773-778.
8. Rajesh K Goel et al, Evaluation of antihyperglycemic activity of some novel monocyclic beta lactums, Journal Pharm Pharmaceutical Science, 2004, 7(1), 80-83.
9. Sayyed Hussain1, Shivaji Jadhav, Megha Rai and Mazahar Farooqui, Synthesis, Characterization and Biological Evaluation of N [3-Chloro-2 (aryl)-4-oxoazitidin-1-y] pyridine-4-carboxamide, International Journal of Drug Design and Discovery. July-September 2011, 2(3), 527-532.
10. Trilok Chandra et al, synthesis of sulfa drug quinazolin-4-one derivative and their evaluation for Anti-inflammatory activity, World Journal of Chemistry, 2009, 4(2), 210-218.
11. Shobhana and Gangwar K.R., Synthesis of 3-chloro-1-[5-(2-hydroxy phenyl)-1,3,4-thiadiazoll-2-yl]-4-substituted azetidin-2-ones derivatives, Indian drug, May 2010, 47(5), 65-68.
12. Ubhash Pande et al, Synthesis and Biological activity of 3-chloro-1-[4-pyrimidine methylcarbonyl amino]-4-phenylazetidin-2-one, European Journal of Chemistry, 2009, 6(5), S91-S96.
13. Vijay Kumar M.M. J et al, N-substituted-3-chloro-2-Azetidinones: Synthesis and Characterization of new novel anti-inflammatory agents, Journal of Pharmaceutical Science and Research, 2009, 1(2), 83-92.
14. V.P. Vaidya et al, Synthesis and investigation of antioxidant and antimicrobial activity of 3-nitro-N-(3-Chloro-2-oxosubstituted-phenyl-azetidin-1-yl) naphtho [2,1-b]furan-2-carboxamide, European Journal of Chemistry, 2010, 7(S1), S358-S362.
15. Bagherwal A. et al, Synthesis and antimicrobial studies of some azetidinones derivatives from Naphthylamine moiety, International Journal of ChemTech Research, Jan-March 2011, 3(1), 274-279.
16. Taraskar M.P. et al, Synthesis and antifungal activity of some azetidinones, International Journal of ChemTech Research, oct-dec 2009,1(4), 1194-1199.