Benefit from bevacizumab for macular edema in central retinal vein occlusion: Twelve-month results of a prospective, randomized study

Ophthalmology

Volumn 119, Issue 12, 2012, Pages 2587-2591

  Epstein, David L ^a   Algvere, Peep V ^a   Von Wendt, Gunvor ^a   Seregard, Stefan ^a   Kvanta, Anders ^a  

^a ST ERIK S EYE HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BEVACIZUMAB;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; ENDOPHTHALMITIS; FEMALE; HUMAN; IRIS RUBEOSIS; MALE; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; RETINA DETACHMENT; RETINA MACULA EDEMA; RETINA TEAR; RETINA VEIN OCCLUSION; TREATMENT DURATION; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT; VISUAL ACUITY;

AGED; ANGIOGENESIS INHIBITORS; ANTIBODIES, MONOCLONAL, HUMANIZED; DOUBLE-BLIND METHOD; FEMALE; GONIOSCOPY; HUMANS; INTRAVITREAL INJECTIONS; MACULAR EDEMA; MALE; PROSPECTIVE STUDIES; RETINAL VEIN OCCLUSION; TOMOGRAPHY, OPTICAL COHERENCE; TREATMENT OUTCOME; VASCULAR ENDOTHELIAL GROWTH FACTOR A; VISUAL ACUITY;

EID: 84870708962     PISSN: 01616420     EISSN: 15494713     Source Type: Journal    
DOI: 10.1016/j.ophtha.2012.06.037     Document Type: Article

References (20)

1. P. Mitchell, W. Smith, A. Chang Prevalence and associations of retinal vein occlusion in Australia: the Blue Mountains Eye Study Arch Ophthalmol 114 1996 1243 1247
2. R. Klein, B.E. Klein, S.E. Moss, S.M. Meuer The epidemiology of retinal vein occlusion: the Beaver Dam Eye Study Trans Am Ophthalmol Soc 98 2000 133 141
3. S. Rogers, R.L. McIntosh, N. Cheung International Eye Disease Consortium The prevalence of retinal vein occlusion: pooled data from population studies from the United States, Europe, Asia, and Australia Ophthalmology 117 2010 313 319
4. R.L. McIntosh, S.L. Rogers, L. Lim Natural history of central retinal vein occlusion: an evidence-based systematic review Ophthalmology 117 2010 1113 1123
5. C. Ehlken, E.S. Rennel, D. Michels Levels of VEGF but not VEGF(165b) are increased in the vitreous of patients with retinal vein occlusion Am J Ophthalmol 152 2011 298 303
6. L.P. Aiello, R.L. Avery, P.G. Arrigg Vascular endothelial growth factor in ocular fluid of patients with diabetic retinopathy and other retinal disorders N Engl J Med 331 1994 1480 1487
7. S.M. Weis, D.A. Cheresh Pathophysiological consequences of VEGF-induced vascular permeability Nature 437 2005 497 504
8. D.M. Brown, P.A. Campochiaro, R.P. Singh CRUISE Investigators Ranibizumab for macular edema following central retinal vein occlusion: six-month primary end point results of a phase III study Ophthalmology 117 2010 1124 1133
9. P.A. Campochiaro, D.M. Brown, C.C. Awh Sustained benefits from ranibizumab for macular edema following central retinal vein occlusion: twelve-month outcomes of a phase III study Ophthalmology 118 2011 2041 2049
10. D. Epstein, P.V. Algvere, G. von Wendt Bevacizumab for macular edema in central retinal vein occlusion: a prospective randomized double masked clinical study Ophthalmology 119 2012 1184 1189
11. J.A. Haller, F. Bandello, R. Belfort Jr OZURDEX GENEVA Study Group Randomized, sham-controlled trial of dexamethasone intravitreal implant in patients with macular edema due to retinal vein occlusion Ophthalmology 117 2010 1134 1146
12. W.S. Yeh, J.A. Haller, P. Lanzetta Effect of the duration of macular edema on clinical outcomes in retinal vein occlusion treated with dexamethasone intravitreal implant Ophthalmology 119 2012 1190 1198
13. M. Ota, A. Tsujikawa, Y. Ojima Retinal sensitivity after resolution of the macular edema associated with retinal vein occlusion Graefes Arch Clin Exp Ophthalmol 250 2012 635 644
14. C.W. Lardenoye, K. Probst, P.J. DeLint, A. Rothova Photoreceptor function in eyes with macular edema Invest Ophthalmol Vis Sci 41 2000 4048 4053
15. R. Klein, S.E. Moss, S.M. Meuer, B.E. Klein The 15-year cumulative incidence of retinal vein occlusion: the Beaver Dam Eye Study Arch Ophthalmol 126 2008 513 518
16. T. Ach, A.E. Hoeh, K.B. Schaal Predictive factors for changes in macular edema in intravitreal bevacizumab therapy of retinal vein occlusion Graefes Arch Clin Exp Ophthalmol 248 2010 155 159
17. J. Beutel, S. Peters, M. Lüke Bevacizumab Study Group Bevacizumab as adjuvant for neovascular glaucoma Acta Ophthalmol 88 2010 103 109
18. T. Wakabayashi, Y. Oshima, H. Sakaguchi Intravitreal bevacizumab to treat iris neovascularization and neovascular glaucoma secondary to ischemic retinal diseases in 41 consecutive cases Ophthalmology 115 2008 1571 1580
19. T.U. Krohne, N. Eter, F.G. Holz, C.H. Meyer Intraocular pharmacokinetics of bevacizumab after a single intravitreal injection in humans Am J Ophthalmol 146 2008 508 512
20. Lucentis (ranibizumab) [package insert] 2011 Novartis Australia New South Wales 3 http://www.novartis.com.au/PI-PDF/luc.pdf Accessed May 23 2012