Receptors and other signaling proteins required for serotonin control of locomotion in Caenorhabditis elegans

Genetics

Volumn 192, Issue 4, 2012, Pages 1359-1371

  Gürel, Güliz ^a   Gustafson, Megan A ^b   Pepper, Judy S ^a   Robert Horvitz, H ^b   Koelle, Michael R ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; ION CHANNEL; MOD 1 PROTEIN; SEROTONIN; SEROTONIN RECEPTOR; SEROTONIN RECEPTOR 4; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; GENE MUTATION; GENETIC SCREENING; GENOTYPE; INTERNEURON; LOCOMOTION; MUSCLE; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; SEROTONIN RELEASE; SEROTONINERGIC NERVE CELL; SIGNAL TRANSDUCTION;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; CHLORIDE CHANNELS; INTERNEURONS; LOCOMOTION; MUSCLES; MUTATION; RECEPTORS, SEROTONIN; SENSORY RECEPTOR CELLS; SEROTONERGIC NEURONS; SEROTONIN;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 84870665194     PISSN: 00166731     EISSN: 19432631     Source Type: Journal    
DOI: 10.1534/genetics.112.142125     Document Type: Article

References (44)

1. Axäng, C., M. Rauthan, D. H. Hall, andM. Pilon, 2008. Developmental genetics of the C. elegans pharyngeal neurons NSML and NSMR. BMC Dev. Biol. 8: 38
2. A receptormediated inhibition in C. elegans. EMBO J. 30: 1852-1863
3. Boulin, T., and J. L. Bessereau, 2007. Mosl-mediated insertional mutagenesis in Caenorhabditis elegans. Nat. Protoc. 2: 1276-1287
4. Brenner, S., 1974. The genetics of Caenorhabditis elegans. Genetics 77: 71-94
5. Bunin, M. A., and R. M. Wightman, 1998. Quantitative evaluation of 5-hydroxytryptamine (serotonin) neuronal release and uptake: an investigation of extrasynaptic transmission. J. Neurosci. 18: 4854-4860
6. Carnell, L., J. Illi, S. W. Hong, and S. L. McIntire, 2005. The G-proteincoupled serotonin receptor SER-1 regulates egg laying and male mating behaviors in Caenorhabditis elegans. J. Neurosci. 25: 10671-10681
7. Chase, D. L., and M. R. Koelle, 2007. Biogenic amine neurotransmitters in C. elegans (February 20, 2007), in WormBook, edited by The C. elegans Research Community, doi/10.1895/wormbook.1.132.1, http://www.wormbook.org
8. Chen, C., S. Tuck, and A. S. Byström, 2009. Defects in tRNA modification associated with neurological and developmental dysfunctions in Caenorhabditis elegans elongator mutants. PLoS Genet. 5: e1000561
9. Cowen, P. J., 2008. Serotonin and depression: Pathophysiological mechanism or marketing myth? Trends Pharmacol. Sci. 29: 433-436
10. Dempsey, C. M., S. M. Mackenzi, A. Gargus, G. Blanco, and S. J. Sze, 2005. Serotonin (5HT), fluoxetine, imipramine and dopamine target distinct 5HT receptor signaling to modulate Caenorhabditis elegans egg-laying behavior. Genetics 169: 1425-1436
11. Dernovici, S., T. Starc, J. A. Dent, and P. Ribeiro, 2007. The serotonin receptor SER-1 (5HT2ce) contributes to the regulation of locomotion in Caenorhabditis elegans. Dev. Neurobiol. 67: 189-204
12. Duerr, J. S., J. Gaskin, and J. B. Rand, 2001. Identified neurons in C. elegans coexpress vesicular transporters for acetylcholine and monoamines. Am. J. Physiol. Cell Physiol. 280: C1616-C1622
13. Edwards, S.L., N. K. Charlie, M. C. Milfort, and B. S. Brown, C. N. Gravlin et al., 2008. A novel molecular solution for ultraviolet light detection in Caenorhabditis elegans. PLoS Biol. 6: e198
14. Ezcurra, M., Y. Tanizawa, P. Swoboda, and W. R. Schafer, 2011. Food sensitizes C. elegans avoidance behaviours through acute dopamine signalling. EMBO J. 30: 1110-1122
15. Fay, D., 2006. Genetic mapping and manipulation: Chapter 1-introduction and basics (February 17, 2006), WormBook, ed
16. The C. elegans Research Community, WormBook, doi/10.1895/ wormbook.1.90.1, http://www.wormbook.org
17. Graham, P. L., J. J. Johnson, S. Wang, M. H. Sibley, M. C. Gupta et al., 1997. Type IV collagen is detectable in most, but not all, basement membranes of Caenorhabditis elegans and assembles on tissues that do not express it. J. Cell Biol. 137: 1171-1183
18. qa activity. Genes Dev. 13: 1780-1793
19. Hapiak, V. M., R. J. Hobson, L. Hughes, K. Smith, G. Harris et al., 2009. Dual excitatory and inhibitory serotonergic inputs modulate egg laying in Caenorhabditis elegans. Genetics 181: 153-163
20. Harris, G. P., V. M. Hapiak, R. T. Wragg, S. B. Miller, L. J. Hughes et al., 2009. Three distinct amine receptors operating at different levels within the locomotory circuit are each essential for the serotonergic modulation of chemosensation in Caenorhabditis elegans. J. Neurosci. 29: 1446-1456
21. Hobson, R. J., V. M. Hapiak, H. Xiao, K. L. Buehrer, P. R. Komuniecki et al., 2006. SER-7, a Caenorhabditis elegans 5-HT7-like receptor, is essential for the 5-HT stimulation of pharyngeal pumping and egg laying. Genetics 172: 159-169
22. Horvitz, H. R., M. Chalfie, C. Trent, J. E. Sulston, and P. D. Evans, 1982. Serotonin and octopamine in the nematode Caenorhabditis elegans. Science 216: 1012-1014
23. Jafari, G., Y. Xie, A. Kullyev, B. Liang, and J. Y. Sze, 2011. Regulation of extrasynaptic 5-HT by serotonin reuptake transporter function in 5-HT-absorbing neurons underscores adaptation behavior in Caenorhabditis elegans. J. Neurosci. 31: 8948-8957
24. Kia, H. K., M. J. Brisorgueil, M. Hamon, A. Calas, and D. Vergé, 1996. Ultrastructural localization of 5-hydroxytryptamine1A receptors in the rat brain. J. Neurosci. Res. 46: 697-708
25. Lochrie, M. A., J. E. Mendel, P. W. Sternberg, and M. I. Simon, 1991. Homologous and unique G protein alpha subunits in the nematode Caenorhabditis elegans. Cell Regul. 2: 135-154
26. Millan, M. J., P. Marin, J. Bockaert, and C. Mannoury la Cour, 2008. Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions. Trends Pharmacol. Sci. 29: 454-464
27. Nelson, L. S., M. L. Rosoff, and C. Li, 1998. Disruption of a neuropeptide gene, flp-1, causes multiple behavioral defects in Caenorhabditis elegans. Science 281: 1686-1690
28. Olde, B., and W. R. McCombie, 1997. Molecular cloning and functional expression of a serotonin receptor from Caenorhabditis elegans. J. Mol. Neurosci. 8: 53-62
29. Otero, G., J. Fellows, Y. Li, and T. de Bizemont, A. M. Dirac et al., 1999. Elongator, a multisubunit component of a novel RNA polymerase II holoenzyme for transcriptional elongation. Mol. Cell 3: 109-118
30. Perroud, N., R. Uher, M. Y. Ng, M. Guipponi, J. Hauser et al., 2010. Genome-wide association study of increasing suicidal ideation during antidepressant treatment in the GENDEP project. Pharmacogenomics J. 12: 68-77
31. Ranganathan, R., S. C. Cannon, and H. R. Horvitz, 2000. MOD-1 is a serotonin-gated chloride channel that modulates locomotory behaviour in C. elegans. Nature 408: 470-475
32. Ranganathan, R., E. R. Sawin, C. Trent, and H. R. Horvitz, 2001. Mutations in the Caenorhabditis elegans serotonin reuptake transporter MOD-5 reveal serotonin-dependent andindependent activities of fluoxetine. J. Neurosci. 21: 5871-5884
33. Sawin, E. R., R. Ranganathan, and H. R. Horvitz, 2000. C. elegans locomotory rate is modulated by the environment through a dopaminergic pathway and by experience through a serotonergic pathway. Neuron 26: 619-631
34. Schafer, W. R., and C. J. Kenyon, 1995. A calcium-channel homologue required for adaptation to dopamine and serotonin in Caenorhabditis elegans. Nature 375: 73-78
35. Ségalat, L., D. A. Elkes, and J. M. Kaplan, 1995. Modulation of serotonin-controlled behaviors by Go in Caenorhabditis elegans. Science 267: 1648-1651
36. Slaugenhaupt, S. A., and J. F. Gusella, 2002. Familial dysautonomia. Curr. Opin. Genet. Dev. 12: 307-311
37. Solinger, J. A., R. Paolinelli, H. Klöss, F. B. Scorza, S. Marchesi et al., 2010. The Caenorhabditis elegans Elongator complex regulates neuronal alpha-tubulin acetylation. PLoS Genet. 6: e1000820
38. Sulston, J., and J. Hodgkin, 1988. Methods, pp. 587-606 in The Nematode Caenorhabditis elegans, edited by W. B. Wood and the Community of C. elegans Researchers. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
39. Sze, J. Y., M. Victor, C. Loer, and Y. Shi, and G. Ruvkun, 2000. Food and metabolic signaling defects in a Caenorhabditis elegans serotonin-synthesis mutant. Nature 403: 560-564
40. Tsalik, E. L., T. Niacaris, A. S. Wenick, K. Pau, L. Avery et al., 2003. LIM homeobox gene-dependent expression of biogenic amine receptors in restricted regions of the C. elegans nervous system. Dev. Biol. 263: 81-102
41. Von Stetina, S. E., M. Treinin, and D. M. Miller, III, 2006. The motor circuit. Int. Rev. Neurobiol. 69: 125-167
42. Waggoner, L. E., L. A. Hardaker, S. Golik, and W. R. Schafer, 2000. Effect of a neuropeptide gene on behavioral states in Caenorhabditis elegans egg-laying. Genetics 154: 1181-1192
43. White, J. G., E. Southgate, J. N. Thomson, and S. Brenner, 1986. The structure of the nervous system of the nematode Caenorhabditis elegans. Philos. Trans. R. Soc. Lond. B Biol. Sci. 314: 1-340
44. Wittschieben, B. O., G. Otero, T. de Bizemont, J. Fellows, H. Erdjument-Bromage et al., 1999. A novel histone acetyltransferase is an integral subunit of elongating RNA polymerase II holoenzyme. Mol. Cell 4: 123-128