Antimicrobial efficacy of a novel eucalyptus oil, chlorhexidine digluconate and isopropyl alcohol biocide formulation

International Journal of Molecular Sciences

Volumn 13, Issue 11, 2012, Pages 14016-14025

  Hendry, Emma ^a   Conway, Barbara ^b   Worthington, Tony ^a  

^a ASTON UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

Author keywords

Biofilm; Chlorhexidine digluconate; Eucalyptus oil; Green biocide; Healthcare associated infection; Surface disinfection

Indexed keywords

2 PROPANOL; CHLORHEXIDINE GLUCONATE; EUCALYPTUS OIL; ANTIINFECTIVE AGENT; CHLORHEXIDINE; DISINFECTANT AGENT; VEGETABLE OIL;

AGAR DIFFUSION; ARTICLE; BACTERIAL GROWTH; CANDIDA ALBICANS; CONTROLLED STUDY; DISINFECTION; ESCHERICHIA COLI; GROWTH INHIBITION; INFECTION CONTROL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; ANALOGS AND DERIVATIVES; BIOFILM; CHEMISTRY; DISK DIFFUSION; DRUG EFFECTS; EUCALYPTUS; MICROBIAL SENSITIVITY TEST;

2-PROPANOL; ANTI-BACTERIAL AGENTS; ANTI-INFECTIVE AGENTS; BIOFILMS; CANDIDA ALBICANS; CHLORHEXIDINE; DISINFECTANTS; DISK DIFFUSION ANTIMICROBIAL TESTS; EUCALYPTUS; MICROBIAL SENSITIVITY TESTS; PLANT OILS;

EID: 84870658274     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms131114016     Document Type: Article

References (20)

1. Griffith, C.J.; Dancer, S.J. Hospital cleaning: Problems with steam cleaning and microfibre. J. Hosp. Infect. 2009, 72, 360-361.
2. Webber, D.J.; Rutala, W.A.; Miller, M.B.; Huslage, K.; Sickbert-Bennett, E. Role of hospital surfaces in the transmission of emerging health care associated pathogens: Norovirus, Clostridium difficile and Acinetobacter species. Am. J. Infect. Control 2010, 38, S25-S33.
3. Dancer, S.J. Importance of the environment in methicillin-resistant Staphylococcus aureus acquisition: The case for hospital cleaning. Lancet Infect. Dis. 2008, 8, 101-113.
4. Bergen, L.K.; Meyer, M.; Hog, M.; Rubenhagen, B.; Anderson, L.P. Spread of bacteria on surfaces when cleaning with microfibre cloths. J. Hosp. Infect. 2009, 71, 132-137.
5. Williams, G.J.; Denyer, S.P.; Hosein, I.K.; Hill, D.W.; Maillard, J.-Y. The development of a new three-step protocol to determine the efficacy of disinfectant wipes on surfaces contaminated with Staphylococcus aureus. J. Hosp. Infect. 2007, 67, 329-335.
6. Rutala, W.A.; Weber, D.J.; the Healthcare Infection Control Practices Advisory Committee (HICPAC). Guideline for the disinfection and sterilization in healthcare facilities. 2008. Available online: http://www.premierinc.com/safety/topics/guidelines/cdc_guidelines.jsp#disin fection-2008 (accessed on 27 August 2010).
7. Hope, C.K.; Wilson, M. Analysis of the effects of chlorhexidine on oral biofilm vitality and structure based on viability profiling and an indicator of membrane integrity. Antimicrob. Agents Chemother. 2004, 48, 1461-1468.
8. Hibbard, J.S.; Mulberry, G.K.; Brady, A.R. A clinical study comparing the skin antisepsis and safety of ChloraPrep®, 70% isopropyl alcohol and 2% aqueous chlorhexidine. J. Infus. Nurs. 2002, 25, 244-249.
9. Karpanen, T.J.; Worthington, T.; Conway, B.R.; Hilton, A.C.; Elliott, T.S.J.; Lambert, P.A. Penetration of chlorhexidine into human skin. Antimicrob. Agents Chemother. 2008, 52, 3633-3636.
10. Karpanen, T.J.; Conway, B.R.; Worthington, T.; Hilton, A.C.; Elliott, T.S.J.; Lambert, P.A. Enhanced chlorhexidine skin penetration with eucalyptus oil. BMC Infect. Dis. 2010, 10, 278-283.
11. Karpanen, T.J.; Worthington, T.; Hendry, E.R.; Conway, B.R.; Lambert, P.A. Antimicrobial efficacy of chlorhexidine digluconate alone and in combination with eucalyptus oil, tea tree oil and thymol against planktonic and biofilm cultures of Staphylococcus epidermidis. J. Antimicrob. Chemother. 2008, 62, 1031-1036.
12. Hendry, E.R.; Worthington, T.; Conway, B.R.; Lambert, P.A. Antimicrobial efficacy of eucalyptus oil and 1,8-cineole alone and in combination with chlorhexidine digluconate against microorganisms grown in planktonic and biofilm cultures. J. Antimicrob. Chemother. 2009, 64, 1219-1225.
13. Bloss, R.; Meyer, S.; Kampf, G. Adsorption of active ingredients of surface disinfectants on the type of fabric used for surface treatment. J. Hosp. Infect. 2010, 75, 56-61.
14. Boyce, J.M.; Bynoe, G.P.; Chenevert, C.; King, T. Environmental contamination due to methicillin-resistant Staphylococcus aureus: Possible infection control implications. Infect. Control Hosp. Epidemiol. 1997, 18, 622-627.
15. Bartz, S.; Ritter, A.C.; Tondo, E.C. Evaluation of bacterial multiplication in cleaning cloths containing different quantities of organic matter. J. Infect. Dev. Countries 2010, 4, 566-571.
16. Moore, G.; Griffih, C. A laboratory evaluation of the decontamination properties of microfibre cloths. J. Hosp. Infect. 2006, 64, 379-385.
17. Mehmi, M.; Marshall, L.J.; Lambert, P.A.; Smith, J.C. Evaluation of disinfecting procedures for aseptic transfer in hospital pharmacy departments. PDA J. Pharm. Sci. Technol. 2009, 63, 123-138.
18. Diab-Elschahawi, M.; Assadian, O.; Blacky, A.; Stadler, M.; Pernicka, E.; Berger, J.; Resch, H.; Koller, W. Evaluation of the decontamination efficacy of new reprocessed microfiber cleaning cloth compared with other commonly used cleaning cloths in the hospital. Am. J. Infect. Control 2010, 38, 289-292.
19. Wren, M.W.D.; Rollins, M.S.M.; Jeanes, A.; Hall, T.J.; Coen, P.G.; Gant, V.A. Removing bacteria from hospital surfaces: A laboratory comparison of ultramicrofibre and standard cloths. J. Hosp. Infect. 2008, 70, 265-271.
20. Miles, A.A.; Misra, S.S. The estimation of the bactericidal power of the blood. J. Hyg. 1938, 38, 732-749.