Fluorescence-guided brain tumor surgery

World Neurosurgery

Volumn 78, Issue 6, 2012, Pages 559-564

  Smith, Luke G F ^a   Nakano, Ichiro ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOLEVULINIC ACID;

ARTICLE; CANCER PROGNOSIS; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; DRUG MEGADOSE; FLUORESCENCE; GLIOBLASTOMA; GLIOMA; HUMAN; HYPOTENSION; NAUSEA; PHOTODYNAMIC THERAPY; SIDE EFFECT; STEREOTACTIC BIOPSY; SYSTEMATIC REVIEW (TOPIC); TREATMENT OUTCOME; VOMITING;

AMINOLEVULINIC ACID; BRAIN NEOPLASMS; GLIOBLASTOMA; HUMANS; MICROSCOPY, FLUORESCENCE; PHOTOSENSITIZING AGENTS; SURGERY, COMPUTER-ASSISTED;

EID: 84870569383     PISSN: 18788750     EISSN: 18788769     Source Type: Journal    
DOI: 10.1016/j.wneu.2012.10.015     Document Type: Article

References (98)

1. R. Agarwal, M. Athar, D.R. Bickers, H. Mukhtar Evidence for the involvement of singlet oxygen in the photodestruction by chloroaluminum phthalocyanine tetrasulfonate Biochem Biophys Res Commun 173 1990 34 41
2. M.L. Agarwal, M.E. Clay, E.J. Harvey, H.H. Evans, A.R. Antunez, N.L. Oleinick Photodynamic therapy induces rapid cell death by apoptosis in L5178Y mouse lymphoma cells Cancer Res 51 1991 5993 5996
3. M. Ammirati, N. Vick, Y.L. Liao, I. Ciric, M. Mikhael Effect of the extent of surgical resection on survival and quality of life in patients with supratentorial glioblastomas and anaplastic astrocytomas Neurosurgery 21 1987 201 206
4. T. Amo, N. Kawanishi, M. Uchida, H. Fujita, E. Oyanagi, T. Utsumi, T. Ogino, K. Inoue, T. Shuin, K. Utsumi, J. Sasaki Mechanism of cell death by 5-aminolevulinic acid-based photodynamic action and its enhancement by ferrochelatase inhibitors in human histiocytic lymphoma cell line U937 Cell Biochem Funct 27 2009 503 515
5. E. Angell-Petersen, S. Spetalen, S. Madsen, C. Sun, Q. Peng, S. Carper, M. Sioud, H. Hirschberg Influence of light fluence rate on the effects of photodynamic therapy in an orthopic rat glioma model J Neurosurg 104 2006 109 117
6. A. Asilian, M. Davami Comparison between the efficacy of photodynamic therapy and topical paromomycin in the treatment of Old World cutaneous leishmaniasis: a placebo-controlled, randomized clinical trial Clin Exp Dermatol 31 2006 634 637
7. G.H. Barnett, D. Kormos, C. Steiner, J. Weisenberger Use of a frameless, armless stereotactic wand for brain tumor localization with two-dimensional and three-dimensional neuroimaging Neurosurgery 33 1993 674 678
8. R. Bhowmick, A.W. Girotti Cytoprotective induction of nitric oxide synthase in a cellular model of 5-aminolevulinic acid-based photodynamic therapy Free Radic Biol Med 48 2010 1296 1301
9. P.C. Burger, S.B. Green Patient age, histologic features, and length of survival in patients with glioblastoma multiforme Cancer 59 1987 1617 1625
10. Central Brain Tumor Registry of the United States CBTUS - Fact Sheet: Central Brain Tumor Registry of the United States 2012 http://www.cbtrus.org/ factsheet/factsheet.html/ Accessed June 6, 2012
11. N.H. Cox, D.J. Eedy, C.A. Morton Guidelines for management of Bowen's disease: 2006 update Therapy Guidelines and Audit Subcommittee, British Association of Dermatologists Br J Dermatol 156 2007 11 21
12. H. Duffau Awake surgery for incidental WHO grade II gliomas involving eloquent areas Acta Neurochir (Wien) 154 2012 575 584 [discussion 584]
13. H. Duffau, L. Capelle, D. Denvil, N. Sichez, P. Gatignol, L. Taillandier, M. Lopes, M.C. Mitchell, S. Roche, J.C. Muller, A. Bitar, J.P. Sichez, R.J. van Effenterre Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a consecutive series of 103 patients Neurosurgery 98 2003 764 778
14. H. Duffau, S. Moritz-Gasser, P. Gatignol Functional outcome after language mapping for insular World Health Organization grade II gliomas in the dominant hemisphere: experience with 24 patients Neurosurg Focus 27 2009 E7
15. M. El-Sharabay, A. El-Wassel, M. Hafez, S. Salim Porphyrin metabolism in some malignant diseases Br J Cancer 65 1992 409 412
16. G.H. Elder, D.L. Williams, V. Marks Haem synthesis and the porphyrias Scientific Foundations of Clinical Biochemistry 1983 Heineman London 175 186
17. S.R. Ennis, A. Novotny, J. Xiang, P. Shakui, T. Masada, W. Stummer, D.E. Smith, R.F. Keep Transport of 5-aminolevulinic acid between blood and brain Brain Res 10 2003 226 234
18. C. Fadul, J. Wood, H. Thaler, J. Galicich, R.H. Patterson Jr, J.B. Posner Morbidity and mortality of craniotomy for excision of supratentorial gliomas Neurology 38 1998 1374 1379
19. K.F. Fan, C. Hopper, P.M. Speight, G. Buonaccorsi, A.J. MacRobert, S.G. Brown Photodynamic therapy using 5-aminolevulinic acid for premalignant and malignant lesions of the oral cavity Cancer 78 1996 1374 1383
20. G.C. Feigl, R. Ritz, M. Moraes, J. Klein, K. Ramina, A. Gharabaghi, B. Krischek, S. Danz, A. Bornemann, M. Liebsch, M.S. Tatagiba Resection of malignant brain tumors in eloquent cortical areas: a new multimodal approach combining 5-aminolevulinic acid and intraoperative monitoring J Neurosurg 113 2010 352 357
21. H.A. Fine, K.B. Dear, J.S. Loeffler, P.M. Black, G.P. Canellos Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults Cancer 71 1993 2585 2597
22. F.W. Floeth, M. Sabel, C. Ewelt, W. Stummer, J. Felsberg, G. Reifenberger, H.J. Steiger, G. Stoffels, H.H. Coenen, K.J. Langen Comparison of (18)F-FET PET and 5-ALA fluorescence in cerebral gliomas Eur J Nucl Med Mol Imaging 38 2011 731 741
23. H. Fukuda, S. Paredes, A.M. Batlle Tumour-localizing properties of porphyrins In vivo studies using free and liposome encapsulated aminolevulinic acid Comp Biochem Physiol B 102 1992 433 436
24. C. Ewelt, M. Goeppert, M. Rapp, H.J. Steiger, W. Stummer, M.J. Sabel Glioblastoma multiforme of the elderly: the prognostic effect of resection on survival J Neurooncol 103 2011 611 618
25. K. Gardlo, Z. Horska, C.D. Enk, L. Rauch, M. Megahed, T. Ruzicka, C. Fritsch Treatment of cutaneous leishmaniasis by photodynamic therapy J Am Acad Dermatol 48 2003 893 896
26. E.A. Gehan, M.D. Walker Prognostic factors for patients with brain tumors Natl Cancer Inst Monogr 46 1977 189 195
27. S.L. Gibson, D.J. Cupriks, J.J. Havens, M.L. Nguyen, R. Hilf A regulatory role for porphobilinogen deaminase (PBGD) in d-amino-laevulinic acid (d-ALA)-induced photosensitization? Br J Cancer 77 1998 235 243
28. W.E. Grant, C. Hopper, A.J. MacRobert, M. Speight, S.G. Bown Photodynamic therapy of oral cancer: photosensitisation with systemic aminolaevulinic acid Lancet 342 1993 147 148
29. W.E. Grant, C. Hopper, A.J. MacRobert, M. Speight, S.G. Bown Oral versus intravenous administration of 5-aminolaevulinic acid for photodynamic therapy Br J Cancer 68 1993 41 51
30. M.A. Hammoud, R. Sawaya, W. Shi, P.F. Thall, N.E. Leeds Prognostic significance of preoperative MRI scans in glioblastoma multiforme J Neurooncol 27 1996 65 73
31. M. Hefti, G. von Campe, M. Moschopulos, A. Siegner, H. Looser, H. Landolt 5-aminolevulinic acid induced protoporphyrin IX fluorescence in high-grade glioma surgery: a one-year experience at a single institution Swiss Med Wkly 138 2008 180 185
32. R. Helseth, E. Helseth, T.B. Johannesen, C.W. Langberg, K. Lote, P. Ronning, D. Scheie, A. Vik, T.R. Meling Overall survival, prognostic factors, and repeated surgery in a consecutive series of 516 patients with glioblastoma multiforme Acta Neurol Scand 122 2010 159 167
33. B.W. Henderson, T.J. Dougherty How does photodynamic therapy work? Photochem Photobiol 55 1992 145 157
34. M.A. Herman, J. Webber, D. Fromm, D. Kessel Hemodynamic effects of 5-aminolevulinic acid in humans J Photochem Photobiol B 43 1998 61 65
35. H. Hirschberg, C. Sun, B. Tromberg, S. Madsen ALA- and ALA-esters-mediated photodynamic therapy of human glioma spheroids J Neurooncol 57 2002 1 7
36. H. Hirschberg, D. Sorensen, E. Angell-Petersen, Q. Peng, B. Tromberg, C. Sun, S. Spetalen, S. Madsen Repetitive photodynamic therapy of malignant brain tumors J Environ Pathol Toxicol Oncol 25 2006 261 280
37. H. Hirschberg, F.A. Uzal, D. Chighvinadze, M.J. Zhang, Q. Peng, S.J. Madsen Disruption of the blood-brain barrier following ALA-mediated photodynamic therapy Lasers Surg Med 40 2008 535 542
38. H. Inoue, Y. Kajimoto, M.A. Shibata, N. Miyoshi, N. Ogawa, S. Miyatake, Y. Otsuki, T. Kuroiwa Massive apoptotic cell death of human glioma cells via a mitochondrial pathway following 5-aminolevulinic acid-mediated photodynamic therapy J Neurooncol 83 2007 223 231
39. S. Ito, W. Rachinger, H. Stepp, H.J. Reulen, W. Stummer Oedema formation in experimental photo-irradiation of brain tumors using 5-ALA Acta Neurochir (Wien) 147 2005 57 65
40. E.W. Jeffes Levulan: the first approved topical photosensitizer for the treatment of actinic keratosis J Dermatol Treat 13 Suppl 1 2002 S19 S23
41. E.W. Jeffes, J.L. McCullough, G.D. Weinstein, R. Kaplan, S.D. Glazer, J.R. Taylor Photodynamic therapy of actinic keratoses with topical aminolevulinic acid hydrochloride and fluorescent blue light J Am Acad Dermatol 45 2001 96 104
42. A. Johansson, G. Palte, O. Schnell, J.C. Tonn, J. Herms, H. Stepp 5-Aminolevulinic acid-induced protoporphyrin IX levels in tissue of human malignant brain tumors Photochem Photobiol 86 2010 1373 1378
43. I. Kausch, M. Sommerauer, F. Montorsi, A. Stenzl, D. Jacqmin, P. Jichlinski, D. Jocham, A. Ziegler, R. Vonthein Photodynamic diagnosis in non-muscle-invasive bladder cancer: a systematic review and cumulative analysis of prospective studies Eur Urol 57 2010 595 606
44. J. Kennedy, R. Pottier Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy Photochem Photobiol 14 1992 275 292
45. J.C. Kennedy, R.H. Pottier, D.C. Pross Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience J Photochem Photobiol B 6 1990 143 148
46. D. Kessel, M.G. Vicente, J.J. Reiners Jr Initiation of apoptosis and autophagy by photodynamic therapy Lasers Surg Med 38 2006 482 488
47. D. Kuhnt, A. Becker, O. Ganslandt, M. Bauer, M. Buchfelder, C. Nimsky Correlation of the extent of tumor volume resection and patient survival in surgery of glioblastoma multiforme with high-field intraoperative MRI guidance J Neurooncol 13 2011 1339 1348
48. D. Kuhnt, O. Ganslandt, S.M. Schlaffer, M. Buchfelder, C. Nimsky Quantification of glioma removal by intraoperative high-field magnetic resonance imaging: an update Neurosurgery 69 2011 852 862 [discussion 862-863]
49. M. Lacroix, D. Abi-Said, D. Fourney, Z. Gokaslan, W. Shi, F. DeMonte, F. Lang, I. McCutcheon, S. Hassenbusch, E. Holland, K. Hess, C. Michael, D. Miller, R.J. Sawaya A multivariate analysis of 416 patients with glioblastoma multiforme: prognosis, extent of resection, and survival Neurosurgery 95 2001 190 198
50. K. Lamborn, S. Chang, M. Prados Prognostic factors for survival of patients with glioblastoma: recursive partitioning analysis J Neurooncol 6 2004 227 235
51. L. Lilge, M.C. Olivo, S.W. Schatz, J.A. Maguire, M.S. Patterson, B.C. Wilson The sensitivity of normal brain and intracranially implanted VX2 tumour to interstitial photodynamic therapy Br J Cancer 73 1996 332 343
52. C.S. Loh, D. Vernon, A.J. MacRobert, J. Bedwell, S.G. Bown, S.B. Brown Endogenous porphyrin distribution induced by 5-aminolaevulinic acid in the tissue layers of the gastrointestinal tract J Photochem Photobiol B 20 1993 47 54
53. S. Madsen, C. Sun, B. Tromberg, V. Wallace, H. Hirschberg Photodynamic therapy of human glioma spheroids using 5-aminolevulinic acid Photochem Photobiol 72 2002 128 134
54. J. Marriott Regulation of porphyrin synthesis Biochem Soc Symp 28 1968 61 74
55. P. Mikvy, H. Messmann, J. Regula, M. Conio, M. Pauer, C.E. Millson, A.J. MacRobert, S.G. Brown Sensitization and photodynamic therapy (PDT) of gastrointestinal tumors with 5-aminolevulinic acid (5-ALA) induced protoporphyrin IX (PPIX) - a pilot study Neoplasma 42 1995 109 113
56. M. Miyake, M. Ishii, K. Kawashima, T. Kodama, K. Sugano, K. Fujimoto, Y. Hirao siRNA-mediated knockdown of the heme synthesis and degradation pathways: modulation of treatment effect of 5-aminolevulinic acid-based photodynamic therapy in urothelial cancer cell lines Photochem Photobiol 85 2009 1020 1027
57. C.A. Morton, C. Whitehurst, H. Moseley, J.H. McColl, J.V. Moore, R.M. Mackie Comparison of photodynamic therapy with cryotherapy in the treatment of Bowen's disease Br J Dermatol 135 1996 766 771
58. A. Nabavi, P.M. Black, D.T. Gering, C.F. Westin, V. Mehta, R.S. Pergolizzi Jr, M. Ferrant, S.K. Warfield, N. Hata, R.B. Schwartz, W.M. Wells 3rd, R. Kikinis, F.A. Jolesz Serial intraoperative magnetic resonance imaging of brain shift Neurosurgery 48 2001 787 797 [discussion 797-798]
59. A. Nabavi, H. Thurm, B. Zountsas, T. Pietsch, H. Lanfermann, U. Pichlmeier, M. Mehdorn 5-ALA Recurrent Glioma Study Group Five-aminolevulinic acid for fluorescence-guided resection of recurrent malignant gliomas: a phase II study J Neurosurg 65 2009 1070 1076 [discussion 1076-1077]
60. H. Ohgaki, P. Kleihues Epidemiology and etiology of gliomas Acta Neuropathol 109 2005 93 108
61. Y. Ohgari, Y. Nakayasu, S. Kitajima, M. Sawamoto, H. Mori, O. Shimokawa, H. Matsui, S. Taketani Mechanisms involved in delta-aminolevulinic acid (ALA)-induced photosensitivity of tumor cells: relation of ferrochelatase and uptake of ALA to the accumulation of protoporphyrin Biochem Pharmacol 71 2005 42 49
62. B. Olzowy, C. Hundt, S. Stocker, K. Bise, H. Reulen, W. Stummer Photoirradiation therapy of experimental malignant glioma with 5-aminilevulinic acid J Neurosurg 97 2002 970 976
63. P.P. Panciani, M. Fontanella, D. Garbossa, A. Agnoletti, A. Ducati, M. Lanotte 5-aminolevulinic acid and neuronavigation in high-grade glioma surgery: results of a combined approach Neurocirugia (Astur) 23 2012 23 28
64. D.J. Piacquadio, D.M. Chen, H.F. Farber, J.F. Fowler Jr, S.D. Glazer, J.J. Goodman, L.L. Hruza, E.W. Jeffes, M.R. Ling, T.J. Phillips, T.M. Rallis, R.K. Scher, C.R. Taylor, G.D. Weinstein Photodynamic therapy with aminolevulinic acid topical solution and visible blue light in the treatment of multiple actinic keratoses of the face and scalp: investigator-blinded, phase 3, multicenter trials Arch Dermatol 140 2004 41 46
65. U. Pichlmeier, A. Bink, G. Schackert, W. Stummer ALA Glioma Study Group Resection and survival in glioblastoma multiforme: an RTOG recursive partitioning analysis of ALA study patients J Neurooncol 10 2008 1025 1034
66. R. Pottier, Y. Chow, J. La Plante, T. Truscott, J. Kennedy, L. Beiner Non-invasive technique for obtaining fluorescence excitation and emission spectra in vivo Photochem Photobiol 44 1986 679 687
67. R. Ramina, M. Coelho Neto, A. Giacomelli, E. Barros Jr, R. Vosgerau, A. Nascimento, G. Coelho Optimizing costs of intraoperative magnetic resonance imaging: a series of 29 glioma cases Acta Neurochir (Wien) 152 2010 27 33
68. J. Regula, A.J. MacRobert, A. Gorchein, G.A. Buonaccorsi, S.M. Thorpe, G.M. Spencer, A.R. Hatfield, S.G. Bown Photosensitisation and photodynamic therapy of oesophageal, duodenal and colorectal tumours using 5-aminolaevulinic acid-induced protoporphyrin IX: a pilot study Gut 36 1995 67 75
69. C.R. Riedl, D. Daniltchenko, F. Koenig, R. Simak, S.A. Loenig, H. Pflueger Fluorescence endoscopy with 5-aminolevulinic acid reduces the early recurrence rate in bladder cancer J Urol 165 2001 1121 1123
70. C. Rimington Porphyrin and haem biosynthesis and its control Acta Med Scand 179 Suppl 445 1966 11 24
71. D. Roberts, A. Hartov, F. Kennedy, M. Miga, K. Paulsen Intraoperative brain shift and deformation: a quantitative analysis of cortical displacement in 28 cases Neurosurgery 43 1988 749 760 [discussion 758-760]
72. D.W. Roberts, P.A. Valdés, B.T. Harris, K.M. Fontaine, A. Hartov, X. Fan, S. Ji, S.S. Lollis, B.W. Pogue, F. Leblond, T.D. Tosteson, B.C. Wilson, K.D. Paulsen Coregistered fluorescence-enhanced tumor resection of malignant glioma: relationships between δ-aminolevulinic acid-induced protoporphyrin IX fluorescence, magnetic resonance imaging enhancement, and neuropathological parameters J Neurosurg 114 2011 595 603
73. N. Sanai, M.S. Berger Glioma extent of resection and its impact on patient outcome Neurosurgery 62 2008 753 764
74. N. Sanai, M.S. Berger Extent of resection influences outcomes for patients with gliomas Rev Neurol (Paris) 167 2011 648 654
75. N. Sanai, Z. Mirzadeh, M.S. Berger Functional outcome after language mapping for glioma resection N Engl J Med 358 2008 18 27
76. N. Sanai, M. Polley, M. McDermott, A. Parsa, M.S. Berger An extent for resection threshold for newly diagnosed glioblastomas J Neurosurg 115 2011 3 8
77. R. Sawaya, M. Hammoud, D. Schoppa, K.R. Hess, S.Z. Wu, W.M. Shi, D.M. Wildrick Neurosurgical outcomes in a modern series of 400 craniotomies for treatment of parenchymal tumors Neurosurgery 42 1998 1044 1055 [discussion 1055-1056]
78. C. Senft, A. Bink, K. Franz, H. Vatter, T. Gasser, V. Seifert Intraoperative MRI guidance and extent of resection in glioma surgery: a randomised, controlled trial Lancet Oncol 12 2011 997 1003
79. C. Senft, K. Franz, S. Blasel, A. Oszvald, J. Rathert, V. Seifert, T. Gasser Influence of iMRI-guidance on the extent of resection and survival of patients with glioblastoma multiforme Technol Cancer Res Treat 2010 9 2010 339 346
80. A.M. Soler, T. Warloe, J. Tausjo, K.E. Giercksky Photodynamic therapy of residual or recurrent basal cell carcinoma after radiotherapy using topical 5-aminolevulinic acid or methylester aminolevulinic acid Acta Oncol 39 2000 605 609
81. R. Sroka, W. Beyer, L. Gossner, T. Sassy, S. Stocker, R. Baumgartner Pharmacokinetics of 5-aminolaevulinic-acid-induced porphyrins in tumour-bearing mice J Photochem Photobiol B 34 1996 13 19
82. D.J. Stewart A critique of the role of the blood-brain barrier in the chemotherapy of human brain tumors J Neurooncol 20 1994 121 139
83. R. Stupp, W.P. Mason, M.J. van den Bent, M. Weller, B. Fisher, M.J. Taphoorn, K. Belanger, A.A. Brandes, C. Marosi, U. Bogdahn, J. Curschmann, R.C. Janzer, S.K. Ludwin, T. Gorlia, A. Allgeier, D. Lacombe, J.G. Cairncross, E. Eisenhauer, R.O. Mirimanoff European Organisation for Research and Treatment of Cancer Brain Tumor and Radiotherapy Groups; National Cancer Institute of Canada Clinical Trials Group Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma N Engl J Med 352 2005 987 996
84. W. Stummer, U. Pichlmeier, T. Meinel, O.D. Wiestler, F. Zanella, H.J. Reulen ALA-Glioma Study Group Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial Lancet Oncol 7 2006 392 401
85. W. Stummer, H.J. Reulen, T. Meinel, U. Pichlmeier, W. Schumacher, J.C. Tonn, V. Rohde, F. Oppel, B. Turowski, C. Woiciechowsky, K. Franz, T. Pietsch ALA-Glioma Study Group Extent of resection and survival in glioblastoma multiforme: identification of and adjustment for bias Neurosurgery 62 2008 564 576 [discussion 564-576]
86. W. Stummer, H. Stepp, G. Möller, A. Ehrhardt, M. Leonhard, H.J. Reulen Technical principles for protoporphyrin-IX fluorescence guided microsurgical resection of malignant glioma tissue Acta Neurochir (Wien) 140 1998 995 1000
87. W. Stummer, S. Stocker, A. Novotny, A. Heimann, O. Sauer, O. Kempski, N. Plesnila, J. Wietsorrek, H.J. Reulen In vitro and in vivo porphyrin accumulation by C6 glioma cells after exposure to 5-aminolevulinic acid J Photochem Photobiol B 45 1998 160 169
88. W. Stummer, S. Stocker, S. Wagner, H. Stepp, C. Fritsch, C. Goetz, A.E. Goetz, R. Kiefmann, H.J. Reulen Intraoperative detection of malignant gliomas by 5-aminolevulinic acid-induced porphyrin fluorescence Neurosurgery 42 1998 518 525 [discussion 525-526]
89. W. Stummer, J.C. Tonn, H.M. Mehdorn, U. Nestler, K. Franz, C. Goetz, A. Bink, U. Pichlmeier ALA-Glioma Study Group Counterbalancing risks and gains from extended resections in malignant glioma surgery a supplemental analysis from the randomized 5-aminolevulinic acid glioma resection study J Neurosurg 114 2010 613 623
90. R. Stupp, M.E. Hegi, W.P. Mason, M.J. van den Bent, M.J. Taphoorn, R.C. Janzer, S.K. Ludwin, A. Allgeier, B. Fisher, K. Belanger, P. Hau, A.A. Brandes, J. Gijtenbeek, C. Marosi, C.J. Vecht, K. Mokhtari, P. Wesseling, S. Villa, E. Eisenhauer, T. Gorlia, M. Weller, D. Lacombe, J.G. Cairncross, R.O. Mirimanoff European Organisation for Research and Treatment of Cancer Brain Tumour and Radiation Oncology Groups; National Cancer Institute of Canada Clinical Trials Group Effects of radiotherapy with concomitant and adjuvant temozolomide versus radiotherapy alone on survival in glioblastoma in a randomised phase III study: 5-year analysis of the EORTC-NCIC trial Lancet Oncol 10 2009 459 466
91. J.C. Tonn, W. Stummer Fluorescence-guided resection of malignant gliomas using 5-aminolevulinic acid: practical use, risks, and pitfalls Clin Neurosurg 55 2008 20 26
92. A. Tsugu, H. Ishizaka, Y. Mizokami, T. Osada, T. Baba, M. Yoshiyama, J. Nishiyama, M. Matsumae Impact of the combination of 5-aminolevulinic acid-induced fluorescence with intraoperative magnetic resonance imaging-guided surgery for glioma World Neurosurg 76 2011 120 127
93. K. Wallner, J. Galicich, G. Krol, E. Arbit, M. Malkin Patterns of failure following treatment for glioblastoma multiforme and anaplastic astrocytoma Int J Radiat Oncol Biol Phys 16 1989 1405 1409
94. J. Webber, Y. Luo, R. Crilly, D. Fromm, D. Kessel An apoptotic response to photodynamic therapy with endogenous protoporphyrin in vivo J Photochem Photobiol B 35 1996 209 211
95. P.A. Valdés, A. Kim, M. Brantsch, C. Niu, Z.B. Moses, T.D. Tosteson, B.C. Wilson, K.D. Paulsen, D.W. Roberts, B.T. Harris δ-aminolevulinic acid-induced protoporphyrin IX concentration correlates with histopathologic markers of malignancy in human gliomas: the need for quantitative fluorescence-guided resection to identify regions of increasing malignancy J Neurooncol 13 2011 846 856
96. V. Vuorinen, S. Hinkka, M. Färkkilä, J. Jääskelä inen Debulking or biopsy of malignant glioma in elderly people - a randomised study Acta Neurochir (Wien) 145 2003 5 10
97. F. Yamamoto, Y. Ohgari, N. Yamaki, S. Kitajima, O. Shimokawa, H. Matsui, S. Taketani The role of nitric oxide in delta-aminolevulinic acid (ALA)-induced photosensitivity of cancerous cells Biochem Biophys Res Commun 353 2007 541 554
98. D. Zaak, M. Kriegmair, H. Stepp, H. Stepp, R. Baumgartner, R. Oberneder, P. Schneede, S. Corvin, D. Frimberger, R. Knüchel, A. Hofstetter Endoscopic detection of transitional cell carcinoma with 5-aminolevulinic acid: results of 1012 fluorescence endoscopies Urology 57 2001 690 694