Elevation of serum thymidine kinase 1 in a bacterial infection: Canine pyometra

Theriogenology

Volumn 79, Issue 1, 2013, Pages 17-23

  Sharif, H ^a   Hagman, R ^a   Wang, L ^a   Eriksson, S ^a  

^a SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Biomarker; Dog TK1; Infection; Pyometra; TK1 activity

Indexed keywords

BIOLOGICAL MARKER; THYMIDINE KINASE; THYMIDINE KINASE 1;

ANIMAL; ANIMAL DISEASE; ARTICLE; BACTERIAL INFECTION; BLOOD; CASE CONTROL STUDY; COHORT ANALYSIS; DOG; DOG DISEASE; FEMALE; METABOLISM; PYOMETRA; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; UPREGULATION;

ANIMALS; BACTERIAL INFECTIONS; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; COHORT STUDIES; DOG DISEASES; DOGS; FEMALE; PYOMETRA; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME; THYMIDINE KINASE; UP-REGULATION;

BACTERIA (MICROORGANISMS); CANIS FAMILIARIS;

EID: 84870552482     PISSN: 0093691X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.theriogenology.2012.09.002     Document Type: Article

References (40)

1. Egenvall A., Hagman R., Bonnett B.N., Hedhammar A., Olson P., Lagerstedt A.S. Breed risk of pyometra in insured dogs in Sweden. J Vet Intern Med 2001, 15:530-538.
2. Sandholm M., Vasenius H., Kivisto A.K. Pathogenesis of canine pyometra. J Am Vet Med Assoc 1975, 167:1006-1010.
3. Fransson B., Lagerstedt A.S., Hellmen E., Jonsson P. Bacteriological findings, blood chemistry profile and plasma endotoxin levels in bitches with pyometra or other uterine diseases. Zentralbl Veterinarmed A 1997, 44:417-426.
4. Hagman R., Kuhn I. Escherichia coli strains isolated from the uterus and urinary bladder of bitches suffering from pyometra. comparison by restriction enzyme digestion and pulsed-field gel electrophoresis. Vet Microbiol 2002, 84:143-153.
5. Nelson R.W., Feldman E.C. Pyometra. Vet Clin North Am Small Anim Pract 1986, 16:561-576.
6. Fransson B., Lagerstedt A.S., Bergstrom A., Hagman R., Park J.S., Chew P.B., et al. C-reactive protein, tumor necrosis factor α, and interleukin-6 in dogs with pyometra and SIRS. J Vet Emerg Crit Care 2007, 17:373-381.
7. Stone E.A., Littman M.P., Robertson J.L., Bovee K.C. Renal dysfunction in dogs with pyometra. J Am Vet Med Assoc 1988, 193:457-464.
8. Van Israel N., Kirby B.M., Munro E.A. Septic peritonitis secondary to unilateral pyometra and ovarian bursal abscessation in a dog. J Small Anim Pract 2002, 43:452-455.
9. Dabrowski R., Wawron W., Kostro K. Changes in CRP, SAA and haptoglobin produced in response to ovariohysterectomy in healthy bitches and those with pyometra. Theriogenology 2007, 67:321-327.
10. Young B., Gleeson M., Cripps A.W. C-reactive protein. a critical review. Pathology 1991, 23:118-124.
11. Nakamura M., Takahashi M., Ohno K., Koshino A., Nakashima K., Setoguchi A., et al. C-reactive protein concentration in dogs with various diseases. J Vet Med Sci 2008, 70:127-131.
12. Hagman R. Serum alpha-1-acid glycoprotein concentrations in 26 dogs with pyometra. Vet Clin Pathol 2011, 40:52-59.
13. Okano S., Tagawa M., Takase K. Relationship of the blood endotoxin concentration and prognosis in dogs with pyometra. J Vet Med Sci 1998, 60:1265-1267.
14. Hagman R., Kindahl H., Lagerstedt A.S. Pyometra in bitches induces elevated plasma endotoxin and prostaglandin F2alpha metabolite levels. Acta Vet Scand 2006, 47:55-67.
15. Vandeplassche M.C.M., De Schepper J. Pyometra in the bitch. Cytological, bacterial, histological and endocrinological characteristics. Vlaams Diergeneeskundig Tijdschrift 1991, 60:207-211.
16. Goodwin J.K., Schaer M. Septic shock. Vet Clin North Am Small Anim Pract 1989, 19:1239-1258.
17. Fox E.S., Thomas P., Broitman S.A. Hepatic mechanisms for clearance and detoxification of bacterial endotoxins. J Nutr Biochem 1990, 1:620-628.
18. Tobias P.S., Soldau K., Ulevitch R.J. Isolation of a lipopolysaccharide-binding acute phase reactant from rabbit serum. J Exp Med 1986, 164:777-793.
19. Eckersall P.D., Bell R. Acute phase proteins: biomarkers of infection and inflammation in veterinary medicine. Vet J 2010, 185:23-27.
20. Hagman R. New aspects of canine pyometra [Doctoral thesis] 2004, Swedish University of Agricultural Sciences, Uppsala.
21. Eriksson S., Munch-Petersen B., Johansson K., Eklund H. Structure and function of cellular deoxyribonucleoside kinases. Cell Mol Life Sci 2002, 59:1327-1346.
22. Ke P.Y., Yang C.C., Tsai I.C., Chang Z.F. Degradation of human thymidine kinase is dependent on serine-13 phosphorylation: involvement of the SCF-mediated pathway. Biochem J 2003, 370:265-273.
23. Ke P.Y., Chang Z.F. Mitotic degradation of human thymidine kinase 1 is dependent on the anaphase-promoting complex/cyclosome-Cdh1-mediated pathway. Mol Cell Biol 2004, 24:514-526.
24. Topolcan O., Holubec L., Polivkova V., Svobodova S., Pesek M., Treska V., et al. Tumor markers in pleural effusions. Anticancer Res 2007, 27:1921-1924.
25. Von Euler H., Einarsson R., Olsson U., Lagerstedt A.S., Eriksson S. Serum thymidine kinase activity in dogs with malignant lymphoma. A potent marker for prognosis and monitoring the disease. J Vet Intern Med 2004, 18:696-702.
26. Gronowitz JS, Fischer LN, Källander CFR. Thymidine Kinase: Biochemical Background and Clinical Applications. 2011. [accessed 22.10.2012]. http://biovica.com/wpcontent/uploads/2011/05/Thymidine_Serum_plasma.pdf.
27. Von Euler H.P., Rivera P., Aronsson A.C., Bengtsson C., Hansson L.O., Eriksson S.K. Monitoring therapy in canine malignant lymphoma and leukemia with serum thymidine kinase 1 activity-evaluation of a new, fully automated non-radiometric assay. Int J Oncol 2009, 34:505-510.
28. Gronowitz J.S., Kallander C.F. The use of herpes virus induced dTk as a marker for serological and direct identification of herpes virus infection in man. Dev Biol Stand 1982, 52:193-204.
29. Tanaka K., Sishido T., Morimoto M., Inoue S., Takamura Y., Masumura M. Elevated serum thymidine kinase activity in patients with acute viral hepatitis. Gastroenterol Jpn 1993, 28:51-55.
30. Suehiro M., Fukuchi M., Kohsaki M., Takemoto Y., Kanamaru A., Kakishita E. Serum thymidine kinase, a possible marker for monitoring the effect of bone marrow transplant treatment in early recovery phase. Ann Nucl Med 1992, 6:79-82.
31. Topolcan O., Holubec L. The role of thymidine kinase in cancer diseases. Expert Opin Med Diagn 2008, 2:129-141.
32. Nakamura N., Momoi Y., Watari T., Yoshino T., Tsujimoto H., Hasegawa A. Plasma thymidine kinase activity in dogs with lymphoma and leukemia. J Vet Med Sci 1997, 59:957-960.
33. Hauptman J.G., Walshaw R., Olivier N.B. Evaluation of the sensitivity and specificity of diagnostic criteria for sepsis in dogs. Vet Surg 1997, 26:393-397.
34. Fransson B.A., Bergstrom A., Wardrop K.J., Hagman R. Assessment of three automated assays for C-reactive protein determination in dogs. Am J Vet Res 2007, 68:1281-1286.
35. Kjelgaard-Hansen M., Kristensen A.T., Jensen A.L. Evaluation of a commercially available enzyme-linked immunosorbent assay (ELISA) for the determination of C-reactive protein in canine serum. J Vet Med A Physiol Pathol Clin Med 2003, 50:164-168.
36. Klenner S., Bauer N., Moritz A. Evaluation of three automated human immunoturbidimetric assays for the detection of C-reactive protein in dogs. J Vet Diagn Invest 2010, 22:544-552.
37. Granström E., Kindahl H. Radioimmunoassay of the major plasma metabolite of PGF2a, 15-keto-13,14-dihydro-PGF2α. Method Enzymol 1982, 86:320-339.
38. Munch-Petersen B. Differences in the kinetic properties of thymidine kinase isoenzymes in unstimulated and phyto-hemagglutinin-stimulated human lymphocytes. Mol Cell Biochem 1984, 64:173-185.
39. Sharif H, Von Euler H, Westberg S, He E, Wang L, Eriksson S. A sensitive and kinetically defined radiochemical assay for canine and human serum thymidine kinase 1 (TK1) to monitor canine malignant lymphoma [e-pub ahead of print]. Vet J. http://dx.doi.org/10.1016/j.tvjl.2012.03.006.
40. Von Euler H., Eriksson S. Comparative aspects of the proliferation marker thymidine kinase 1 in human and canine tumour diseases. Vet Comp Oncol 2011, 9:1-15.