Structural insights into the mechanism of four-coordinate cob(II)alamin formation in the active site of the salmonella enterica ATP:Co(I)rrinoid adenosyltransferase enzyme: Critical role of residues Phe91 and Trp93

Biochemistry

Volumn 51, Issue 48, 2012, Pages 9647-9657

  Moore, Theodore C ^a   Newmister, Sean A ^a   Rayment, Ivan ^a   Escalante Semerena, Jorge C ^b  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b UNIVERSITY OF GEORGIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 ,6-DIMETHYLBENZIMIDAZOLE; ACTIVE SITE; ADENOSYLCOBALAMIN; CO-C BOND; COBALT ION; IN-VITRO; IN-VIVO; MUTATIONAL ANALYSIS; REDOX POTENTIALS; SALMONELLA ENTERICA; SIDE-CHAINS; STRUCTURAL INSIGHTS;

COBALT; ENZYMES; HYDROPHOBICITY; LIGANDS; REDOX REACTIONS; SALMONELLA;

COBALT COMPOUNDS;

COBALAMIN; COBAMAMIDE;

ARTICLE; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ENZYME STRUCTURE; HYDROPHOBICITY; IN VITRO STUDY; IN VIVO STUDY; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; SALMONELLA ENTERICA;

CATALYTIC DOMAIN; KINETICS; MODELS, MOLECULAR; PHENYLALANINE; PROTEIN CONFORMATION; SALMONELLA ENTERICA; TRANSFERASES; TRYPTOPHAN; VITAMIN B 12;

SALMONELLA ENTERICA;

EID: 84870535221     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301378d     Document Type: Article

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