Collaborative role of the pediatrician in the diagnosis and management of bipolar disorder in adolescents

Pediatrics

Volumn 130, Issue 6, 2012, Pages

  Shain, Benjamin N ^a   Braverman, Paula K ^a   Adelman, William P ^a   Breuner, Cora C ^a   Levine, David A ^a   Marcell, Arik V ^a   Murray, Pamela J ^a   O'Brien, Rebecca F ^a  

^a NONE

Author keywords

Adolescent bipolar disorder; Collaboration; Interview guidelines; Psychiatric diagnosis; Psychotropic medication

Indexed keywords

ANTIDEPRESSANT AGENT; ARIPIPRAZOLE; ASENAPINE; ATYPICAL ANTIPSYCHOTIC AGENT; CARBAMAZEPINE; CLOZAPINE; GABAPENTIN; ILOPERIDONE; LAMOTRIGINE; LITHIUM CARBONATE; LITHIUM DERIVATIVE; LURASIDONE; MOOD STABILIZER; OLANZAPINE; ORAL CONTRACEPTIVE AGENT; OXCARBAZEPINE; PALIPERIDONE; QUETIAPINE; RISPERIDONE; TOPIRAMATE; VALPROATE SEMISODIUM; ZIPRASIDONE;

ACNE; ADOLESCENT; AGITATION; AGRANULOCYTOSIS; AKATHISIA; APLASTIC ANEMIA; APPETITE; ASTHENIA; ATAXIA; BIPOLAR I DISORDER; BIPOLAR II DISORDER; BLURRED VISION; CLINICAL ARTICLE; COGNITIVE DEFECT; COMA; CONFUSION; COORDINATION DISORDER; CYCLOTHYMIA; DEATH; DEPRESSION; DIARRHEA; DIZZINESS; DSM-IV; DYSARTHRIA; DYSKINESIA; FATIGUE; FEMALE; HAIR LOSS; HEADACHE; HEALTH CARE PERSONNEL; HEART MUSCLE CONDUCTION DISTURBANCE; HUMAN; HYPERSEXUALITY; HYPOMANIA; HYPONATREMIA; HYPOPARATHYROIDISM; HYPOTHYROIDISM; KIDNEY FUNCTION; LEUKOPENIA; LIVER FAILURE; MALE; MANIA; MENTAL HEALTH; MULTIPLE ORGAN FAILURE; NAUSEA; NEPHROLITHIASIS; NEUTROPENIA; OVARY POLYCYSTIC DISEASE; PANCREATITIS; PARKINSONISM; PEDIATRICIAN; PHENOTYPE; POLYURIA; PREVALENCE; PRIORITY JOURNAL; PSYCHOEDUCATION; PSYCHOMOTOR DISORDER; PSYCHOPHARMACOLOGY; QT INTERVAL; REVIEW; SEDATION; SEIZURE; SEXUAL DYSFUNCTION; SIDE EFFECT; SKIN MANIFESTATION; SOCIAL STATUS; STEVENS JOHNSON SYNDROME; TARDIVE DYSKINESIA; THROMBOCYTOPENIA; TREMOR; VOMITING; WEIGHT GAIN;

ADOLESCENT; AGE FACTORS; ANTICONVULSANTS; ANTIMANIC AGENTS; BIPOLAR DISORDER; CHILD; COMBINED MODALITY THERAPY; COMORBIDITY; COOPERATIVE BEHAVIOR; DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DRUG THERAPY, COMBINATION; HUMANS; INTERDISCIPLINARY COMMUNICATION; INTERVIEW, PSYCHOLOGICAL; PATIENT ADMISSION; PATIENT CARE TEAM; PATIENT EDUCATION AS TOPIC; PEDIATRICS; PSYCHOTHERAPY; RECURRENCE;

EID: 84870533259     PISSN: 00314005     EISSN: 10984275     Source Type: Journal    
DOI: 10.1542/peds.2012-2756     Document Type: Review

References (80)

1. American Academy of Child and Adolescent Psychiatry. Practice parameters for the assessment and treatment of children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2007;46(1):107-122
2. Carlson GA. Early onset bipolar disorder: clinical and research considerations. J Clin Child Adolesc Psychol. 2005;34(2):333-343 (Pubitemid 40855444)
3. Blader JC, Carlson GA. Increased rates of bipolar disorder diagnoses among U.S. child, adolescent, and adult inpatients, 1996-2004. Biol Psychiatry. 2007;62(2):107-114 (Pubitemid 46963252)
4. Akiskal HS, Pinto O. The evolving bipolar spectrum. Prototypes I, II, III, and IV. Psychiatr Clin North Am. 1999;22(3):517-534, vii (Pubitemid 29463705)
5. Kowatch RA, Fristad MA, Findling RL, eds. Clinical Manual for Management of Bipolar Disorder in Children and Adolescents. Washington, DC: American Psychiatric Publishing Inc; 2009
6. Drotar D, Greenley RN, Demeter CA, et al. Adherence to pharmacological treatment for juvenile bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2007;46(7):831-839 (Pubitemid 46975919)
7. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision (DSM-IV-TR). Washington, DC: American Psychiatric Association; 2000
8. Kramlinger KG, Post RM. Ultra-rapid and ultradian cycling in bipolar affective illness. Br J Psychiatry. 1996;168(3):314-323
9. Geller B, Williams M, Zimerman B, Frazier J, Beringer L, Warner KL. Prepubertal and early adolescent bipolarity differentiate from ADHD by manic symptoms, grandiose delusions, ultra-rapid or ultradian cycling. J Affect Disord. 1998;51(2):81-91 (Pubitemid 29101682)
10. Pavuluri MN, Birmaher B, Naylor MW. Pediatric bipolar disorder: a review of the past 10 years. J Am Acad Child Adolesc Psychiatry. 2005;44(9):846-871 (Pubitemid 41193198)
11. Axelson D, Birmaher B, Strober M, et al. Phenomenology of children and adolescents with bipolar spectrum disorders. Arch Gen Psychiatry. 2006;63(10):1139-1148 (Pubitemid 44498393)
12. Birmaher B, Axelson D, Strober M, et al. Clinical course of children and adolescents with bipolar spectrum disorders. Arch Gen Psychiatry. 2006;63(2):175-183 (Pubitemid 43213879)
13. Axelson DA, Birmaher B, Strober MA, et al. Course of subthreshold bipolar disorder in youth: diagnostic progression from bipolar disorder not otherwise specified. J Am Acad Child Adolesc Psychiatry. 2011;50(10):1001.e3-1016.e3
14. Leibenluft E, Charney DS, Towbin KE, Bhangoo RK, Pine DS. Defining clinical phenotypes of juvenile mania. Am J Psychiatry. 2003;160(3):430-437 (Pubitemid 41094250)
15. Brotman MA, Schmajuk M, Rich BA, et al. Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children. Biol Psychiatry. 2006;60(9):991-997 (Pubitemid 44739929)
16. Brotman MA, Kassem L, Reising MM, et al. Parental diagnoses in youth with narrow phenotype bipolar disorder or severe mood dysregulation. Am J Psychiatry. 2007;164(8):1238-1241 (Pubitemid 47292413)
17. American Psychiatric Association. D 00 disruptive mood dysregulation disorder. DSM-5 Development. Available at: www.dsm5.org/ProposedRevision/Pages/ proposedrevision.aspx?rid=397#. Accessed February 14, 2012
18. Kowatch RA, Fristad M, Birmaher B, Wagner KD, Findling RL, Hellander M; Child Psychiatric Workgroup on Bipolar Disorder. Treatment guidelines for children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2005;44(3):213-235 (Pubitemid 40299835)
19. Sederer LI, Summergrad P. Criteria for hospital admission. Hosp Community Psychiatry. 1993;44(2):116-118 (Pubitemid 23075191)
20. Kiser LJ, Heston JD, Millsap PA, Pruitt DB. Treatment protocols in child and adolescent day treatment. Hosp Community Psychiatry. 1991;42(6):597-600
21. Teich JL, Ireys HT. A national survey of state licensing, regulating, and monitoring of residential facilities for children with mental illness. Psychiatr Serv. 2007;58(7):991-998 (Pubitemid 47122879)
22. Connolly SD, Bernstein GA; Work Group on Quality Issues. Practice parameter for the assessment and treatment of children and adolescents with anxiety disorders. J Am Acad Child Adolesc Psychiatry. 2007;46(2):267-283
23. Birmaher B, Brent D, Bernet W, et al AACAP Work Group on Quality Issues. Practice parameter for the assessment and treatment of children and adolescents with depressive disorders. J Am Acad Child Adolesc Psychiatry. 2007;46(11):1503-1526
24. Pliszka S; AACAP Work Group on Quality Issues. Practice parameter for the assessment and treatment of children and adolescents with attention-deficit/ hyperactivity disorder. J Am Acad Child Adolesc Psychiatry. 2007;46(7):894-921
25. American Academy of Child and Adolescent Psychiatry. Practice parameter on the use of psychotropic medication in children and adolescents. J Am Acad Child Adolesc Psychiatry. 2009;48(9):961-973
26. US Food and Drug Administration. Drugs@FDA [database]. Available at: www.accessdata.fda.gov/scripts/cder/drugsatfda/index.cfm. Accessed February 14, 2012
27. Kowatch RA, Sethuraman G, Hume JH, Kromelis M, Weinberg WA. Combination pharmacotherapy in children and adolescents with bipolar disorder. Biol Psychiatry. 2003;53(11):978-984 (Pubitemid 36645228)
28. Correll CU. Weight gain and metabolic effects of mood stabilizers and antipsychotics in pediatric bipolar disorder: a systematic review and pooled analysis of short-term trials. J Am Acad Child Adolesc Psychiatry. 2007;46(6):687-700 (Pubitemid 46816822)
29. Correll CU. Antipsychotic use in children and adolescents: minimizing adverse effects to maximize outcomes. J Am Acad Child Adolesc Psychiatry. 2008;47(1):9-20
30. Olfson M, Blanco C, Liu L, Moreno C, Laje G. National trends in the outpatient treatment of children and adolescents with antipsychotic drugs. Arch Gen Psychiatry. 2006;63(6):679-685 (Pubitemid 43848299)
31. Patel NC, Hariparsad M, Matias-Akthar M, et al. Body mass indexes and lipid profiles in hospitalized children and adolescents exposed to atypical antipsychotics. J Child Adolesc Psychopharmacol. 2007;17(3):303-311 (Pubitemid 47067954)
32. Klein DJ, Cottingham EM, Sorter M, Barton BA, Morrison JA. A randomized, double-blind, placebo-controlled trial of metformin treatment of weight gain associated with initiation of atypical antipsychotic therapy in children and adolescents. Am J Psychiatry. 2006;163(12):2072-2079 (Pubitemid 46114226)
33. Shin L, Bregman H, Breeze JL, Noyes N, Frazier JA. Metformin for weight control in pediatric patients on atypical antipsychotic medication. J Child Adolesc Psychopharmacol. 2009;19(3):275-279
34. American Diabetes Association; American Psychiatric Association; American Association of Clinical Endocrinologists; North American Association for the Study of Obesity. Consensus development conference on antipsychotic drugs and obesity and diabetes. J Clin Psychiatry. 2004;65(2):267-272
35. Goldberg JF. Antidepressants in bipolar disorder: 7 myths and realities. Curr Psychiatry. 2010;9(5):41-48
36. Pavuluri MN, Henry DB, Devineni B, Carbray JA, Naylor MW, Janicak PG. A pharmacotherapy algorithm for stabilization and maintenance of pediatric bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2004;43(7):859-867 (Pubitemid 38808491)
37. Scheffer RE, Linden S. Concurrent medical conditions with pediatric bipolar disorder. Curr Opin Psychiatry. 2007;20(4):398-401 (Pubitemid 46889668)
38. Weeke A. Juel Knud, Vaerth M. Cardiovascular death and manic-depressive psychosis. J Affect Disord. 1987;13(3):287-292 (Pubitemid 18049394)
39. Taylor V, MacQueen G. Associations between bipolar disorder and metabolic syndrome: A review. J Clin Psychiatry. 2006;67(7):1034-1041 (Pubitemid 44230873)
40. Duffy A, Alda M, Hajek T, Grof P. Early course of bipolar disorder in high-risk offspring: prospective study. Br J Psychiatry. 2009;195(5):457-458
41. Wagner KD, Weller EB, Carlson GA, et al. An open-label trial of divalproex in children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2002;41(10):1224-1230 (Pubitemid 38338042)
42. Henry CA, Zamvil LS, Lam C, Rosenquist KJ, Ghaemi SN. Long-term outcome with divalproex in children and adolescents with bipolar disorder. J Child Adolesc Psychopharmacol. 2003;13(4):523-529 (Pubitemid 38174242)
43. Wagner KD, Redden L, Kowatch RA, et al. A double-blind, randomized, placebo-controlled trial of divalproex extended-release in the treatment of bipolar disorder in children and adolescents. J Am Acad Child Adolesc Psychiatry. 2009;48(5):519-532
44. Chang K, Saxena K, Howe M. An open-label study of lamotrigine adjunct or monotherapy for the treatment of adolescents with bipolar depression. J Am Acad Child Adolesc Psychiatry. 2006;45(3):298-304
45. Pavuluri MN, Henry DB, Moss M, Mohammed T, Carbray JA, Sweeney JA. Effectiveness of lamotrigine in maintaining symptom control in pediatric bipolar disorder. J Child Adolesc Psychopharmacol. 2009;19(1):75-82
46. Strober M, Morrell W, Lampert C, Burroughs J. Relapse following discontinuation of lithium maintenance therapy in adolescents with bipolar I illness: a naturalistic study. Am J Psychiatry. 1990;147(4):457-461 (Pubitemid 20107110)
47. Geller B, Cooper TB, Sun K, et al. Double-blind and placebo-controlled study of lithium for adolescent bipolar disorders with secondary substance dependency. J Am Acad Child Adolesc Psychiatry. 1998;37(2):171-178 (Pubitemid 28099184)
48. Kafantaris V, Coletti DJ, Dicker R, Padula G, Kane JM. Lithium treatment of acute mania in adolescents: a large open trial. J Am Acad Child Adolesc Psychiatry. 2003;42(9):1038-1045 (Pubitemid 39571826)
49. Kafantaris V, Coletti DJ, Dicker R, Padula G, Pleak RR, Alvir JM. Lithium treatment of acute mania in adolescents: a placebo-controlled discontinuation study. J Am Acad Child Adolesc Psychiatry. 2004;43(8):984-993 (Pubitemid 38971720)
50. Patel NC, DelBello MP, Bryan HS, et al. Open-label lithium for the treatment of adolescents with bipolar depression. J Am Acad Child Adolesc Psychiatry. 2006;45(3):289-297
51. Wagner KD, Kowatch RA, Emslie GJ, et al. A double-blind, randomized, placebo-controlled trial of oxcarbazepine in the treatment of bipolar disorder in children and adolescents. Am J Psychiatry. 2006;163(7):1179-1186 (Pubitemid 44464445)
52. DelBello MP, Kowatch RA, Warner J, et al. Adjunctive topiramate treatment for pediatric bipolar disorder: a retrospective chart review. J Child Adolesc Psychopharmacol. 2002;12(4):323-330 (Pubitemid 36169284)
53. Barzman DH, DelBello MP, Kowatch RA, et al. Adjunctive topiramate in hospitalized children and adolescents with bipolar disorders. J Child Adolesc Psychopharmacol. 2005;15(6):931-937 (Pubitemid 43042984)
54. Delbello MP, Findling RL, Kushner S, et al. A pilot controlled trial of topiramate for mania in children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2005;44(6):539-547 (Pubitemid 40720953)
55. Barzman DH, DelBello MP, Kowatch RA, et al. The effectiveness and tolerability of aripiprazole for pediatric bipolar disorders: a retrospective chart review. J Child Adolesc Psychopharmacol. 2004;14(4):593-600
56. Biederman J, McDonnell MA, Wozniak J, et al. Aripiprazole in the treatment of pediatric bipolar disorder: a systematic chart review. CNS Spectr. 2005;10(2):141-148 (Pubitemid 40327779)
57. Biederman J, Mick E, Spencer T, et al. An open-label trial of aripiprazole monotherapy in children and adolescents with bipolar disorder. CNS Spectr. 2007;12(9):683-689 (Pubitemid 47571968)
58. Tramontina S, Zeni CP, Pheula GF, de Souza CK, Rohde LA. Aripiprazole in juvenile bipolar disorder comorbid with attention-deficit/hyperactivity disorder: an open clinical trial. CNS Spectr. 2007;12(10):758-762 (Pubitemid 350072173)
59. Findling RL, Nyilas M, Forbes RA, et al. Acute treatment of pediatric bipolar I disorder, manic or mixed episode, with aripiprazole: a randomized, double-blind, placebo-controlled study. J Clin Psychiatry. 2009;70(10):1441-1451
60. Tramontina S, Zeni CP, Ketzer CR, Pheula GF, Narvaez J, Rohde LA. Aripiprazole in children and adolescents with bipolar disorder comorbid with attention-deficit/hyperactivity disorder: a pilot randomized clinical trial. J Clin Psychiatry. 2009;70(5):756-764
61. Masi G, Mucci M, Millepiedi S. Clozapine in adolescent inpatients with acute mania. J Child Adolesc Psychopharmacol. 2002;12(2):93-99 (Pubitemid 34779023)
62. Frazier JA, Biederman J, Tohen M, et al. A prospective open-label treatment trial of olanzapine monotherapy in children and adolescents with bipolar disorder. J Child Adolesc Psychopharmacol. 2001;11(3):239-250 (Pubitemid 32937636)
63. Tohen M, Kryzhanovskaya L, Carlson G, et al. Olanzapine versus placebo in the treatment of adolescents with bipolar mania. Am J Psychiatry. 2007;164(10):1547-1556 (Pubitemid 350069734)
64. Joshi G, Mick E, Wozniak J, et al. Impact of obsessive-compulsive disorder on the antimanic response to olanzapine therapy in youth with bipolar disorder. Bipolar Disord. 2010;12(2):196-204
65. DelBello MP, Adler CM, Whitsel RM, Stanford KE, Strakowski SM. A 12-week single-blind trial of quetiapine for the treatment of mood symptoms in adolescents at high risk for developing bipolar I disorder. J Clin Psychiatry. 2007;68(5):789-795 (Pubitemid 46841865)
66. DelBello MP, Chang K, Welge JA, et al. A double-blind, placebo-controlled pilot study of quetiapine for depressed adolescents with bipolar disorder. Bipolar Disord. 2009;11(5):483-493
67. Scheffer RE, Tripathi A, Kirkpatrick FG, Schultz T. Rapid quetiapine loading in youths with bipolar disorder. J Child Adolesc Psychopharmacol. 2010;20(5):441-445
68. Frazier JA, Meyer MC, Biederman J, et al. Risperidone treatment for juvenile bipolar disorder: a retrospective chart review. J Am Acad Child Adolesc Psychiatry. 1999;38(8):960-965 (Pubitemid 29353030)
69. Biederman J, Mick E, Wozniak J, Aleardi M, Spencer T, Faraone SV. An open-label trial of risperidone in children and adolescents with bipolar disorder. J Child Adolesc Psychopharmacol. 2005;15(2):311-317 (Pubitemid 40734110)
70. Haas M, Delbello MP, Pandina G, et al. Risperidone for the treatment of acute mania in children and adolescents with bipolar disorder: a randomized, double-blind, placebo-controlled study. Bipolar Disord. 2009;11(7):687-700
71. Carlson GA, Potegal M, Margulies D, Basile J, Gutkovich Z. Liquid risperidone in the treatment of rages in psychiatrically hospitalized children with possible bipolar disorder. Bipolar Disord. 2010;12(2):205-212
72. Krieger FV, Pheula GF, Coelho R, et al. An open-label trial of risperidone in children and adolescents with severe mood dysregulation. J Child Adolesc Psychopharmacol. 2011;21(3):237-243
73. Biederman J, Mick E, Spencer T, Dougherty M, Aleardi M, Wozniak J. A prospective open-label treatment trial of ziprasidone monotherapy in children and adolescents with bipolar disorder. Bipolar Disord. 2007;9(8):888-894 (Pubitemid 350215115)
74. Kowatch RA, Suppes T, Carmody TJ, et al. Effect size of lithium, divalproex sodium, and carbamazepine in children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2000;39(6):713-720 (Pubitemid 30351221)
75. Delbello MP, Schwiers ML, Rosenberg HL, Strakowski SM. A double-blind, randomized, placebo-controlled study of quetiapine as adjunctive treatment for adolescent mania. J Am Acad Child Adolesc Psychiatry. 2002;41(10):1216-1223 (Pubitemid 38338041)
76. Pavuluri MN, Henry DB, Carbray JA, Sampson G, Naylor MW, Janicak PG. Open-label prospective trial of risperidone in combination with lithium or divalproex sodium in pediatric mania. J Affect Disord. 2004;82(suppl 1):S103-S111 (Pubitemid 39574988)
77. Findling RL, McNamara NK, Youngstrom EA, et al. Double-blind 18-month trial of lithium versus divalproex maintenance treatment in pediatric bipolar disorder. J Am Acad Child Adolesc Psychiatry. 2005;44(5):409-417 (Pubitemid 40559688)
78. DelBello MP, Kowatch RA, Adler CM, et al. A double-blind randomized pilot study comparing quetiapine and divalproex for adolescent mania. J Am Acad Child Adolesc Psychiatry. 2006;45(3):305-313
79. MacMillan CM, Withney JE, Korndörfer SR, Tilley CA, Mrakotsky C, Gonzalez-Heydrich JM. Comparative clinical responses to risperidone and divalproex in patients with pediatric bipolar disorder. J Psychiatr Pract. 2008;14(3):160-169 (Pubitemid 351787172)
80. Pavuluri MN, Henry DB, Findling RL, et al. Double-blind randomized trial of risperidone versus divalproex in pediatric bipolar disorder. Bipolar Disord. 2010;12(6):593-605