Long-Term Outcome with Divalproex in Children and Adolescents with Bipolar Disorder

Journal of Child and Adolescent Psychopharmacology

Volumn 13, Issue 4, 2003, Pages 523-529

  Henry, Charles A ^a,b   Zamvil, Linda S ^a,b   Lam, Christopher ^a,b   Rosenquist, Klara J ^a,b   Ghaemi, S Nassir ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b CAMBRIDGE HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMFEBUTAMONE; AMPHETAMINE DERIVATIVE; CITALOPRAM; CLONIDINE; DEXAMPHETAMINE; DIPHENHYDRAMINE; LEVOTHYROXINE; LITHIUM CARBONATE; PAROXETINE; QUETIAPINE; RISPERIDONE; SERTRALINE; VALPROATE SEMISODIUM;

ADOLESCENT; ADULT; BEHAVIOR; BIPOLAR DISORDER; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; DEPRESSION; DIZZINESS; DOSE RESPONSE; DRUG SAFETY; FEMALE; HAIR LOSS; HUMAN; HYPOTHYROIDISM; LIVER TOXICITY; LONG TERM CARE; MALE; MANIA; NAUSEA; PSYCHIATRIC DIAGNOSIS; REVIEW; SCORING SYSTEM; SEDATION; SIDE EFFECT; TREATMENT OUTCOME; VOMITING; WEIGHT GAIN;

EID: 0842267736     PISSN: 10445463     EISSN: None     Source Type: Journal    
DOI: 10.1089/104454603322724913     Document Type: Review

References (44)

1. Allarakhia IN, Garofalo EA, Komarynski MA, Robertson PL: Valproic acid and thrombocytopenia in children: A case-controlled retrospective study. Pediatr Neurol 14:303-307, 1996.
2. Alvarez-Gomez MJ, Vaamonde J, Narbona J, Barao M, Barona P, Brannan T, Gudin M, Ibanez R: Parkinsonian syndrome in childhood after sodium valproate administration. Clin Neuropharmacol 16:451-455, 1993.
3. American Psychiatric Association: Diagnostic and Statistical Manual of Mental Disorders, 4th ed. (DSM-IV). Washington (DC), American Psychiatric Association, 1994.
4. Armon C, Shin C, Miller P, Carwile S, Brown E, Edinger JD, Paul RG: Reversible parkinsonism and cognitive impairment with chronic valproate use. Neurology 47:626-635, 1996.
5. Asconape JJ, Penry JK, Dreifuss FE, Riela A, Mirza W: Valproate-associated pancreatitis. Epilepsia 34:177-183, 1993.
6. Bowden CL, Brugger AM, Swann AC, Calabrese JR, Janicak PG, Petty F, Dilsaver SC, Davis JM, Rush AJ, Small JG: Efficacy of divalproex vs lithium and placebo in the treatment of mania. The Depakote Mania Study Group. JAMA 271:918-924, 1994.
7. Bowden CL, Calabrese JR, McElroy SL, Gyulai L, Wassef A, Petty F, Pope HG Jr, Chou JC, Keck PE Jr, Rhodes LJ, Swann AC, Hirschfeld RM, Wozniak PJ: A randomized, placebo-controlled 12-month trial of divalproex and lithium in treatment of outpatients with bipolar I disorder. Divalproex Maintenance Study Group. Arch Gen Psychiatry 57:481-489, 2000.
8. Breum L, Astrup A, Gram L, Andersen T, Stokholm KH, Christensen NJ, Werdelin L, Madsen J: Metabolic changes during treatment with valproate in humans: Implication for untoward weight gain. Metabolism 41:666-670, 1992.
9. Calabrese J, Delucchi GA: Spectrum of efficacy of valproate in 55 patients with rapid-cycling bipolar disorder. Am J Psychiatry 147:431-434, 1990.
10. Corman CL, Leung NM, Guberman AH: Weight gain in epileptic patients during treatment with valproic acid: A retrospective study. Can J Neurol Sci 24:240-244, 1997.
11. Deltito JA, Levitan J, Damore J, Hajal F, Zambenedetti M: Naturalistic experience with the use of divalproex sodium on an in-patient unit for adolescent psychiatric patients. Acta Psychiatr Scand 97:236-240, 1998.
12. Demir E, Aysun S: Weight gain associated with valproate in childhood. Pediatr Neurol 22:361-364, 2000.
13. Dreifuss FE, Santilli N, Langer DH, Sweeney KP, Moline KA, Menander KB: Valproic acid hepatic fatalities: A retrospective review. Neurology 37: 379-385, 1987.
14. Eberle AJ: Valproate and polycystic ovaries. J Am Acad Child Adolesc Psychiatry 37:1009, 1998.
15. Eiris-Punal J, Del Rio-Garma M, del Rio-Garma MC, Lojo-Rocamonde S, Novo-Rodriguez I, Castro-Gago M: Long-term treatment of children with epilepsy with valproate or carbamazepine may cause subclinical hypothyroidism. Epilepsia 40:1761-1766, 1999.
16. Geller B: BPD and ADHD: Dr. Geller replies. J Am Acad Child Adolesc Psychiatry 36:720, 1997.
17. Guille C, Sachs GS, Ghaemi SN: A naturalistic comparison of clozapine, risperidone, and olanzapine in the treatment of bipolar disorder. J Clin Psychiatry 61:638-642, 2000.
18. Guy W: ECDEU Assessment Manual for Psychopharmacology, Revised. Rockville (Maryland), U.S. Department of Health, Education, and Welfare, 1976.
19. Irwin, M, Masand P: Valproate and polycystic ovaries. J Am Acad Child Adolesc Psychiatry 37:9-10, 1998.
20. Isojarvi JI, Laatikainen TJ, Knip M, Pakarinen AJ, Juntunen KT, Myllyla VV: Obesity and endocrine disorders in women taking valproate for epilepsy. Ann Neurol 39:579-584, 1996.
21. Isojarvi JI, Laatikainen TJ, Pakarinen AJ, Juntunen KT, Myllyla VV: Polycystic ovaries and hyperandrogenism in women taking valproate for epilepsy. N Engl J Med 329:1383-1388, 1993.
22. Johnston HF: More on valproate and polycystic ovaries. J Am Acad Child Adolesc Psychiatry 38:354, 1999.
23. Kowatch RA, Suppes T, Carmody TJ, Bucci JP, Hume JH, Kromelis M, Emslie GJ, Weinberg WA, Rush AJ: Effect size of lithium, divalproex sodium, and carbamazepine in children and adolescents with bipolar disorder. J Am Acad Child Adolesc Psychiatry 39:713-720, 2000.
24. Lambert P, Venaud G: Comparative study of valpromide versus lithium in the treatment of affective disorders. Nervure 5:57-65, 1992.
25. McElroy SL, Keck PE Jr, Pope HG Jr: Sodium valproate: Its use in primary psychiatric disorders. J Clin Psychopharmacol 7:16-24, 1987.
26. Mota-Castillo M, Torruella A, Engels B, Perez J, Dedrick C, Gluckman M: Valproate in very young children: An open case series with a brief follow-up. J Affect Disord 67:193-197, 2001.
27. Novak GP, Maytal J, Alshansky A, Eviatar L, Sy-Kho R, Siddique Q: Risk of excessive weight gain in epileptic children treated with valproate. J Child Neurol 14:490-495, 1999.
28. Papatheodorou G, Kutcher SP: Divalproex sodium treatment in late adolescent and young adult acute mania. Psychopharmacol Bull 29:213-219, 1993.
29. Papatheodorou G, Kutcher SP, Katic M, Szalai JP: The efficacy and safety of divalproex sodium in the treatment of acute mania in adolescents and young adults: An open clinical trial. J Clin Psychopharmacol 15:110-116, 1995.
30. Pope HG Jr, McElroy SL, Keck PE Jr, Hudson JI: Valproate in the treatment of acute mania. A placebo-controlled study. Arch Gen Psychiatry 48:62-68, 1991.
31. Rasgon NL, Altshuler LL, Gudeman D, Burt VK, Tanavoli S, Hendrick V, Korenman S: Medication status and polycystic ovary syndrome in women with bipolar disorder: A preliminary report. J Clin Psychiatry 61:173-178, 2000.
32. Rattya J, Turkka J, Pakarinen AJ, Knip M, Kotila MA, Lukkarinen O, Myllyla VV, Isojarvi JI: Reproductive effects of valproate, carbamazepine, and oxcarbazepine in men with epilepsy. Neurology 56:31-36, 2001.
33. Rattya J, Vainionpaa L, Knip M, Lanning P, Isojarvi JI: The effects of valproate, carbamazepine, and oxcarbazepine on growth and sexual maturation in girls with epilepsy. Pediatrics 103:588-593, 1999.
34. Salvatoni A, Martini C, Cammareri V: Hypothyroidism and sodium valproate. J Pediatr 103:1005-1006, 1983.
35. Sanchez L, Hagino O, Weller E, Weller R: Bipolarity in children. Psychiatr Clin North Am 22:629-648, 1999.
36. Scheffner D: Fatal liver failure in children on valproate. Lancet 2:511, 1986.
37. Schmidt A, Darius J, Brosz M, Roth N, Meyer FP, Kroker S, Wien F, Brett B: [The effect of valproic acid monotherapy on behavior and cognitive performance of children with idiopathic generalized epilepsy]. Z Kinder Jugendpsychiatr 23: 161-170, 1995.
38. Straussberg R, Kivity S, Weitz R, Harel L, Gadoth N: Reversible cortical atrophy and cognitive decline induced by valproic acid. Eur J Paediatr Neurol 2:213-218, 1998.
39. Vainionpaa LK, Rattya J, Knip M, Tapanainen JS, Pakarinen AJ, Lanning P, Tekay A, Myllyla VV, Isojarvi JI: Valproate-induced hyperandrogenism during pubertal maturation in girls with epilepsy. Ann Neurol 45:444-450, 1999.
40. Vaquerizo J, Gomez Martin H, Gonzalez Iglesias E, Cardesa JJ: [Reversible neuropsychological deterioration associated with valproate]. Revista de Neurologia 23:148-150, 1995.
41. West SA, Keck PE Jr, McElroy SL: Open trial of valproate in the treatment of adolescent mania. J Child Adolesc Psychopharmacol 4:263-267, 1994.
42. West SA, Keck PE Jr, McElroy SL: Oral loading dose in the valproate treatment of adolescents with mixed bipolar disorder. J Child Adolesc Psychopharmacol 5:225-231, 1996.
43. Wozniak J, Biederman J, Richards JA: Diagnostic and therapeutic dilemmas in the management of pediatric-onset bipolar disorder. J Clin Psychiatry 62:10-15, 2001.
44. Wyllie E, Wyllie R, Cruse RP, Erenberg G, Rothner AD: Pancreatitis associated with valproic acid therapy. Am J Dis Child 138:912-914, 1984.