Mutations to A/Puerto Rico/8/34 PB1 gene improves seasonal reassortant influenza A virus growth kinetics

Vaccine

Volumn 31, Issue 1, 2012, Pages 207-212

  Plant, Ewan P ^a   Liu, Teresa M ^a   Xie, Hang ^a   Ye, Zhiping ^a  

^a CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

Author keywords

Influenza; Polymerase; Protein yield; Vaccine

Indexed keywords

HEMAGGLUTININ; INFLUENZA VACCINE; SIALIDASE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CULTURE MEDIUM; FEMALE; GENE MUTATION; HUMAN; HUMAN CELL; INFLUENZA VIRUS A; INFLUENZA VIRUS A H3N2; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEASONAL INFLUENZA; VIROGENESIS; VIRUS GENE; VIRUS GENE PB1; VIRUS REPLICATION; VIRUS STRAIN;

ANIMALS; FEMALE; INFLUENZA A VIRUS; INFLUENZA VACCINES; MICE; MICE, INBRED BALB C; MUTATION; ORTHOMYXOVIRIDAE INFECTIONS;

EID: 84870505976     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2012.10.060     Document Type: Article

References (27)

1. Kilbourne E.D. Future influenza vaccines and the use of genetic recombinants. Bull World Health Organ 1969, 41(3):643-645.
2. Fulvini A.A., Ramanunninair M., Le J., Pokorny B.A., Arroyo J.M., Silverman J., et al. Gene constellation of influenza A virus reassortants with high growth phenotype prepared as seed candidates for vaccine production. PLoS ONE 2011, 6(6):e20823.
3. Neumann G., Watanabe T., Ito H., Watanabe S., Goto H., Gao P., et al. Generation of influenza A viruses entirely from cloned cDNAs. Proc Natl Acad Sci USA 1999, 96(August (16)):9345-9350.
4. Hoffmann E., Neumann G., Kawaoka Y., Hobom G., Webster R.G. A DNA transfection system for generation of influenza A virus from eight plasmids. Proc Natl Acad Sci USA 2000, 97(May (11)):6108-6113.
5. Fodor E., Devenish L., Engelhardt O.G., Palese P., Brownlee G.G., Garcia-Sastre A. Rescue of influenza A virus from recombinant DNA. J Virol 1999, 73(November (11)):9679-9682.
6. Gerdil C. The annual production cycle for influenza vaccine. Vaccine 2003, 21(May (16)):1776-1779.
7. Wise H.M., Barbezange C., Jagger B.W., Dalton R.M., Gog J.R., Curran M.D., et al. Overlapping signals for translational regulation and packaging of influenza A virus segment 2. Nucleic Acids Res 2011, 39(September (17)):7775-7790.
8. Bartlam M., Lou Z., Liu Y., Rao Z. Polymerase structure and function. Influenza molecular biology 2010, 137-152. Caister Academic Press, Norfolk. Q. Wang, Y.J. Tao (Eds.).
9. Dudek S.E., Wixler L., Nordhoff C., Nordmann A., Anhlan D., Wixler V., et al. The influenza virus PB1-F2 protein has interferon antagonistic activity. Biol Chem 2011, 392(December (12)):1135-1144.
10. Krumbholz A., Philipps A., Oehring H., Schwarzer K., Eitner A., Wutzler P., et al. Current knowledge on PB1-F2 of influenza A viruses. Med Microbiol Immunol 2011, 200(May (2)):69-75.
11. Wise H.M., Foeglein A., Sun J., Dalton R.M., Patel S., Howard W., et al. A complicated message: identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA. J Virol 2009, 83(August (16)):8021-8031.
12. Tauber S., Ligertwood Y., Quigg-Nichol M., Dutia B., Elliott R. Behaviour of influenza A viruses differentially-expressing segment 2 gene products in vitro and in vivo. J Gen Virol 2012, 93(April (pt4)):840-849.
13. Rudneva I.A., Timofeeva T.A., Shilov A.A., Kochergin-Nikitsky K.S., Varich N.L., Ilyushina N.A., et al. Effect of gene constellation and postreassortment amino acid change on the phenotypic features of H5 influenza virus reassortants. Arch Virol 2007, 152(6):1139-1145.
14. Wanitchang A., Kramyu J., Jongkaewwattana A. Enhancement of reverse genetics-derived swine-origin H1N1 influenza virus seed vaccine growth by inclusion of indigenous polymerase PB1 protein. Virus Res 2010, 147(January (1)):145-148.
15. Abt M., de J.J., Laue M., Wolff T. Improvement of H5N1 influenza vaccine viruses: influence of internal gene segments of avian and human origin on production and hemagglutinin content. Vaccine 2011, 29(July (32)):5153-5162.
16. Harvey R., Hamill M., Robertson J.S., Minor P.D., Vodeiko G.M., Weir J.P., et al. Application of deglycosylation to SDS PAGE analysis improves calibration of influenza antigen standards. Biologicals 2012, 40(January (1)):96-99.
17. Poch O., Sauvaget I., Delarue M., Tordo N. Identification of four conserved motifs among the RNA-dependent polymerase encoding elements. EMBO J 1989, 8(December (12)):3867-3874.
18. Chu C., Fan S., Li C., Macken C., Kim J.H., Hatta M., et al. Functional analysis of conserved motifs in influenza virus PB1 protein. PLoS ONE 2012, 7(5):e36113.
19. Gonzalez S., Zurcher T., Ortin J. Identification of two separate domains in the influenza virus PB1 protein involved in the interaction with the PB2 and PA subunits: a model for the viral RNA polymerase structure. Nucleic Acids Res 1996, 24(November (22)):4456-4463.
20. Perez D.R., Donis R.O. Functional analysis of PA binding by influenza a virus PB1: effects on polymerase activity and viral infectivity. J Virol 2001, 75(September (17)):8127-8136.
21. Ghanem A., Mayer D., Chase G., Tegge W., Frank R., Kochs G., et al. Peptide-mediated interference with influenza A virus polymerase. J Virol 2007, 81(July (14)):7801-7804.
22. Sugiyama K., Obayashi E., Kawaguchi A., Suzuki Y., Tame J.R., Nagata K., et al. Structural insight into the essential PB1-PB2 subunit contact of the influenza virus RNA polymerase. EMBO J 2009, 28(June (12)):1803-1811.
23. Wasilenko J.L., Lee C.W., Sarmento L., Spackman E., Kapczynski D.R., Suarez D.L., et al. NP, PB1, and PB2 viral genes contribute to altered replication of H5N1 avian influenza viruses in chickens. J Virol 2008, 82(May (9)):4544-4553.
24. Xu C., Hu W.B., Xu K., He Y.X., Wang T.Y., Chen Z., et al. Amino acids 473V and 598P of PB1 from an avian-origin influenza A virus contribute to polymerase activity, especially in mammalian cells. J Gen Virol 2012, 93(March (Pt 3)):531-540.
25. Li J., Li Y., Hu Y., Chang G., Sun W., Yang Y., et al. PB1-mediated virulence attenuation of H5N1 influenza virus in mice is associated with PB2. J Gen Virol 2011, 92(June (Pt 6)):1435-1444.
26. Hulse-Post D.J., Franks J., Boyd K., Salomon R., Hoffmann E., Yen H.L., et al. Molecular changes in the polymerase genes (PA and PB1) associated with high pathogenicity of H5N1 influenza virus in mallard ducks. J Virol 2007, 81(August (16)):8515-8524.
27. Vodeiko G.M., McInnis J., Chizhikov V., Levandowski R.A. Genetic phenotypic analysis of reassortants of high growth and low growth strains of influenza B virus. Vaccine 2003, 21(September (25-26)):3867-3874.