Application of deglycosylation to SDS PAGE analysis improves calibration of influenza antigen standards

Biologicals

Volumn 40, Issue 1, 2012, Pages 96-99

  Harvey, Ruth ^a   Hamill, Michelle ^a   Robertson, James S ^a   Minor, Philip D ^a   Vodeiko, Galina M ^b   Weir, Jerry P ^b   Takahashi, Hitoshi ^c   Harada, Yuichi ^c   Itamura, Shigeyuki ^c   Bamford, Pearl ^d   Dalla Pozza, Tania ^d   Engelhardt, Othmar G ^a  

^a NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^b CENTER FOR BIOLOGICS EVALUATION AND RESEARCH   (United States)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^d THERAPEUTIC GOODS ADMINISTRATION   (Australia)

Author keywords

Calibration; Deglycosylation; HA; Influenza; Standardisation; Standards; Vaccine

Indexed keywords

INFLUENZA VACCINE; VIRUS ANTIGEN; VIRUS HEMAGGLUTININ;

ARTICLE; CALIBRATION; CONTROLLED STUDY; DEGLYCOSYLATION; FREEZE DRYING; IMMUNODIFFUSION; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H3N2; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONTENT; PROTEIN PURIFICATION;

ANTIGENS, VIRAL; CALIBRATION; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCOSYLATION; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA A VIRUS, H3N2 SUBTYPE; INFLUENZA VACCINES; WORLD HEALTH ORGANIZATION;

ORTHOMYXOVIRIDAE;

EID: 84856451518     PISSN: 10451056     EISSN: 10958320     Source Type: Journal    
DOI: 10.1016/j.biologicals.2011.12.009     Document Type: Article

References (10)

1. Germann T.C., Kadau K., Longini I.M., Macken C.A. Mitigation strategies for pandemic influenza in the United States. PNAS 2006, 103:5935-5940.
2. Russell C.A., Jones T.C., Barr I.G., Cox N.J., Garten R.J., Gregory V., et al. Influenza vaccine strain selection and recent studies on the global migration of seasonal influenza viruses. Vaccine 2008, 26S:D31-D34.
3. Tosh P.K., Jacobson R.M., Poland G.A. Influenza vaccines: from surveillance through production to protection. Mayo Clin Proc 2010, 85(3):257-273.
4. Orenstein W.A., Schaffner W. Lessons Learned: Role of influenza vaccine production, distribution, supply and demand - What it means for the provider. Am J Med 2008, 121:S22-S27.
5. Wood J.M., Schild G.C., Newman R.M., Seagroatt V. An improved single-radial-immunodiffusion technique for the assay of influenza haemagglutinin antigen: application for the potency determinations of inactivated whole virus and subunit vaccines. JBiol Stand 1977, 5:237-247.
6. WHO WHO Expert committee on Biological Standardization 1979, Thirteenth report, World Health Organisation, Geneva, Annex 3 (WHO Technical Report Series, No. 638).
7. Wood J.M., Mumford J.A., Dunleavy U., Seagroatt V., Newman R.W., Thornton D., et al. Single radial immunodiffusion potency tests for inactivated equine influenza vaccines. Equine infection disease V. Proc. Fifth International Conference 1988, 74-79. The University Press, Kentucky. D.G. Powell (Ed.).
8. Harvey R., Wheeler J.X., Wallis C.L., Robertson J.S., Engelhardt O.G. Quantitation of haemagglutinin in H5N1 influenza viruses reveals low haemagglutinin content of vaccine virus NIBRG-14 (H5N1). Vaccine 2008, 26:6550-6554.
9. Hsu J.C. Multiple comparisons, Theory and methods 1996, Chapman and Hall.
10. Li C., Shao M., Cui X., Song Y., Li J., Yuan L., et al. Application of deglycosylation and electrophoresis to the quantification of influenza viral hemagglutinins facilitating the production of 2009 pandemic influenza (H1N1) vaccines at multiple manufacturing sites in China. Biologicals 2010, 38:284-289.