메뉴 건너뛰기




Volumn 4, Issue 1, 2012, Pages 569-576

Protection of bone in premenopausal women with breast cancer: Focus on zoledronic acid

Author keywords

Breast cancer; Premenopausal; Zoledronic acid

Indexed keywords

ANALGESIC AGENT; ANASTROZOLE; ANTINEOPLASTIC AGENT; AROMATASE INHIBITOR; CLODRONIC ACID; DENOSUMAB; ESTROGEN; GOSERELIN; PAMIDRONIC ACID; PLACEBO; RISEDRONIC ACID; TAMOXIFEN; ZOLEDRONIC ACID;

EID: 84870505022     PISSN: None     EISSN: 11791411     Source Type: Journal    
DOI: 10.2147/IJWH.S29101     Document Type: Review
Times cited : (6)

References (66)
  • 2
    • 0030749321 scopus 로고    scopus 로고
    • Skeletal complications of malignancy
    • Coleman RE. Skeletal complications of malignancy. Cancer. 1997;80(8 Suppl):1588-1594.
    • (1997) Cancer. , vol.80 , Issue.8 SUPPL. , pp. 1588-1594
    • Coleman, R.E.1
  • 3
    • 0036675220 scopus 로고    scopus 로고
    • Metastasis to bone: Causes, consequences and therapeutic opportunities
    • Mundy GR. Metastasis to bone: causes, consequences and therapeutic opportunities. Nat Rev Cancer. 2002;2(8):584-593.
    • (2002) Nat Rev Cancer. , vol.2 , Issue.8 , pp. 584-593
    • Mundy, G.R.1
  • 4
    • 40749088124 scopus 로고    scopus 로고
    • New research findings on zoledronic acid: Survival, pain, and anti-tumour effects
    • Saad F. New research findings on zoledronic acid: survival, pain, and anti-tumour effects. Cancer Treat Rev. 2008;34(2):183-192.
    • (2008) Cancer Treat Rev. , vol.34 , Issue.2 , pp. 183-192
    • Saad, F.1
  • 5
    • 18144427879 scopus 로고    scopus 로고
    • The significance of skeletal-related events for the health-related quality of life of patients with metastatic prostate cancer
    • Weinfurt KP, Li Y, Castel LD, etal. The significance of skeletal-related events for the health-related quality of life of patients with metastatic prostate cancer. Ann Oncol. 2005;16(4):579-584.
    • (2005) Ann Oncol. , vol.16 , Issue.4 , pp. 579-584
    • Weinfurt, K.P.1    Li, Y.2    Castel, L.D.3    et al4
  • 6
    • 77954254610 scopus 로고    scopus 로고
    • National Osteoporosis Foundation, Washington, DC: National Osteoporosis Foundation, Available from, Accessed 4 April 2012
    • National Osteoporosis Foundation. Clinician's Guide to Prevention and Treatment of Osteoporosis. Washington, DC: National Osteoporosis Foundation; 2010. Available from: http://www.nof.org. Accessed 4 April 2012.
    • (2010) Clinician's Guide to Prevention and Treatment of Osteoporosis
  • 7
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG)
    • Early Breast Cancer Trialists' Collaborative Group (EBCTCG). Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials. Lancet. 2005;365(9472):1687-1717.
    • (2005) Lancet. , vol.365 , Issue.9472 , pp. 1687-1717
  • 8
    • 41949094767 scopus 로고    scopus 로고
    • Effect of anastrozole on bone mineral density: 5-year results from the anastrozole, tamoxifen, alone or in combination trial 18233230
    • Eastell R, Adams JE, Coleman RE, etal. Effect of anastrozole on bone mineral density: 5-year results from the anastrozole, tamoxifen, alone or in combination trial 18233230. J Clin Oncol. 2008;26(7):1051-1057.
    • (2008) J Clin Oncol. , vol.26 , Issue.7 , pp. 1051-1057
    • Eastell, R.1    Adams, J.E.2    Coleman, R.E.3    et al4
  • 9
    • 49949115926 scopus 로고    scopus 로고
    • Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy
    • for Austrian Breast and Colorectal Cancer Study Group (ABSCG)
    • Gnant M, Mlineritsch B, Luschin-Ebengreuth G, etal; for Austrian Breast and Colorectal Cancer Study Group (ABSCG). Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy. Lancet Oncol. 2008;9(9):840-849.
    • (2008) Lancet Oncol. , vol.9 , Issue.9 , pp. 840-849
    • Gnant, M.1    Mlineritsch, B.2    Luschin-Ebengreuth, G.3    et al4
  • 10
    • 79952101885 scopus 로고    scopus 로고
    • Zoledronic acid preserves bone mineral density in premenopausal women who develop ovarian failure due to adjuvant chemotherapy: Final results from CALGB trial 79809
    • Shapiro CL, Halabi S, Hars V, etal. Zoledronic acid preserves bone mineral density in premenopausal women who develop ovarian failure due to adjuvant chemotherapy: final results from CALGB trial 79809. Eur J Cancer. 2011;47(5):683-689.
    • (2011) Eur J Cancer. , vol.47 , Issue.5 , pp. 683-689
    • Shapiro, C.L.1    Halabi, S.2    Hars, V.3    et al4
  • 11
    • 33644842287 scopus 로고    scopus 로고
    • Tamoxifen treatment after adjuvant chemotherapy has opposite effects on bone mineral density in premenopausal patients depending on menstrual status
    • Vehmanen L, Elomaa I, Blomqvist C, Saarto T. Tamoxifen treatment after adjuvant chemotherapy has opposite effects on bone mineral density in premenopausal patients depending on menstrual status. J Clin Oncol. 2006;24(4):675-680.
    • (2006) J Clin Oncol. , vol.24 , Issue.4 , pp. 675-680
    • Vehmanen, L.1    Elomaa, I.2    Blomqvist, C.3    Saarto, T.4
  • 12
    • 56449088739 scopus 로고    scopus 로고
    • Aromatase inhibitor-associated bone loss in breast cancer patients is distinct from postmenopausal osteoporosis
    • Hadji P. Aromatase inhibitor-associated bone loss in breast cancer patients is distinct from postmenopausal osteoporosis. Crit Rev Oncol Hematol. 2009;69(1):73-82.
    • (2009) Crit Rev Oncol Hematol. , vol.69 , Issue.1 , pp. 73-82
    • Hadji, P.1
  • 13
    • 84859110852 scopus 로고    scopus 로고
    • East Hanover, NJ: Novartis Pharmaceuticals Corporation
    • Zometa®(zoledronic acid) [package insert]. East Hanover, NJ: Novartis Pharmaceuticals Corporation; 2011.
    • (2011) Zometa®(zoledronic acid) [package insert]
  • 15
    • 0031057249 scopus 로고    scopus 로고
    • Bisphosphonate risedronate prevents bone loss in women with artificial menopause due to chemotherapy of breast cancer: A double-blind, placebo-controlled study
    • Delmas PD, Balena R, Confravreux E, Hardouin C, Hardy P, Bremond A. Bisphosphonate risedronate prevents bone loss in women with artificial menopause due to chemotherapy of breast cancer: a double-blind, placebo-controlled study. J Clin Oncol. 1997;15(3):955-962.
    • (1997) J Clin Oncol. , vol.15 , Issue.3 , pp. 955-962
    • Delmas, P.D.1    Balena, R.2    Confravreux, E.3    Hardouin, C.4    Hardy, P.5    Bremond, A.6
  • 16
    • 21244494910 scopus 로고    scopus 로고
    • Pamidronate in the prevention of chemotherapy-induced bone loss in premenopausal women with breast cancer: A randomized controlled trial
    • Fuleihan GE, Salamoun M, Mourad YA, etal. Pamidronate in the prevention of chemotherapy-induced bone loss in premenopausal women with breast cancer: a randomized controlled trial. J Clin Endocrinol Metab. 2005;90(6):3209-3214.
    • (2005) J Clin Endocrinol Metab. , vol.90 , Issue.6 , pp. 3209-3214
    • Fuleihan, G.E.1    Salamoun, M.2    Mourad, Y.A.3    et al4
  • 17
    • 54249151531 scopus 로고    scopus 로고
    • Zoledronic acid prevents bone loss in premenopausal women undergoing adjuvant chemotherapy for early-stage breast cancer
    • Hershman DL, McMahon DJ, Crew KD, etal. Zoledronic acid prevents bone loss in premenopausal women undergoing adjuvant chemotherapy for early-stage breast cancer. J Clin Oncol. 2008;26(29):4739-4745.
    • (2008) J Clin Oncol. , vol.26 , Issue.29 , pp. 4739-4745
    • Hershman, D.L.1    McMahon, D.J.2    Crew, K.D.3    et al4
  • 18
    • 76149130691 scopus 로고    scopus 로고
    • Prevention of bone loss by zoledronic acid in premenopausal women undergoing adjuvant chemotherapy persist up to one year following discontinuing treatment
    • Hershman DL, McMahon DJ, Crew KD, etal. Prevention of bone loss by zoledronic acid in premenopausal women undergoing adjuvant chemotherapy persist up to one year following discontinuing treatment. J Clin Endocrinol Metab. 2010;95(2):559-566.
    • (2010) J Clin Endocrinol Metab. , vol.95 , Issue.2 , pp. 559-566
    • Hershman, D.L.1    McMahon, D.J.2    Crew, K.D.3    et al4
  • 19
    • 78651104412 scopus 로고    scopus 로고
    • Zoledronic acid prevents bone loss in premenopausal women with early breast cancer undergoing adjuvant chemotherapy: A phase III trial of the Korean Cancer Study Group (KCSG-BR06-01)
    • Kim JE, Ahn JH, Jung KH, etal. Zoledronic acid prevents bone loss in premenopausal women with early breast cancer undergoing adjuvant chemotherapy: a phase III trial of the Korean Cancer Study Group (KCSG-BR06-01). Breast Cancer Res Treat. 2011;125(1):99-106.
    • (2011) Breast Cancer Res Treat. , vol.125 , Issue.1 , pp. 99-106
    • Kim, J.E.1    Ahn, J.H.2    Jung, K.H.3    et al4
  • 20
    • 0032490125 scopus 로고    scopus 로고
    • Oral clodronate and reduction in loss of bone mineral density in women with operable primary breast cancer
    • Powles TJ, McCloskey E, Paterson AH, etal. Oral clodronate and reduction in loss of bone mineral density in women with operable primary breast cancer. J Natl Cancer Inst. 1998;90(9):704-708.
    • (1998) J Natl Cancer Inst. , vol.90 , Issue.9 , pp. 704-708
    • Powles, T.J.1    McCloskey, E.2    Paterson, A.H.3    et al4
  • 21
    • 1842405434 scopus 로고    scopus 로고
    • Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro
    • Frith JC, Monkkonen J, Blackburn GM, Russell RG, Rogers MJ. Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5′-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro. J Bone Miner Res. 1997;12(9):1358-1367.
    • (1997) J Bone Miner Res. , vol.12 , Issue.9 , pp. 1358-1367
    • Frith, J.C.1    Monkkonen, J.2    Blackburn, G.M.3    Russell, R.G.4    Rogers, M.J.5
  • 22
    • 69249219178 scopus 로고    scopus 로고
    • Targeting the mevalonate pathway for improved anticancer therapy
    • Fritz G. Targeting the mevalonate pathway for improved anticancer therapy. Curr Cancer Drug Targets. 2009;9(5):626-638.
    • (2009) Curr Cancer Drug Targets. , vol.9 , Issue.5 , pp. 626-638
    • Fritz, G.1
  • 23
    • 33646725498 scopus 로고    scopus 로고
    • The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs
    • Kavanagh KL, Guo K, Dunford JE, etal. The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs. Proc Natl Acad Sci U S A. 2006;103(20):7829-7834.
    • (2006) Proc Natl Acad Sci U S A. , vol.103 , Issue.20 , pp. 7829-7834
    • Kavanagh, K.L.1    Guo, K.2    Dunford, J.E.3    et al4
  • 24
    • 33947109369 scopus 로고    scopus 로고
    • Bisphosphonates: Mode of action and pharmacology
    • Russell RG. Bisphosphonates: mode of action and pharmacology. Pediatrics. 2007;119(Suppl 2):S150-S162.
    • (2007) Pediatrics. , vol.119 , Issue.SUPPL. 2
    • Russell, R.G.1
  • 25
    • 0031977199 scopus 로고    scopus 로고
    • Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras
    • Luckman SP, Hughes DE, Coxon FP, Graham R, Russell G, Rogers MJ. Nitrogen-containing bisphosphonates inhibit the mevalonate pathway and prevent post-translational prenylation of GTP-binding proteins, including Ras. J Bone Miner Res. 1998;13(4):581-589.
    • (1998) J Bone Miner Res. , vol.13 , Issue.4 , pp. 581-589
    • Luckman, S.P.1    Hughes, D.E.2    Coxon, F.P.3    Graham, R.4    Russell, G.5    Rogers, M.J.6
  • 26
    • 33644539542 scopus 로고    scopus 로고
    • A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates
    • Monkkonen H, Auriola S, Lehenkari P, etal. A new endogenous ATP analog (ApppI) inhibits the mitochondrial adenine nucleotide translocase (ANT) and is responsible for the apoptosis induced by nitrogen-containing bisphosphonates. Br J Pharmacol. 2006;147(4):437-445.
    • (2006) Br J Pharmacol. , vol.147 , Issue.4 , pp. 437-445
    • Monkkonen, H.1    Auriola, S.2    Lehenkari, P.3    et al4
  • 29
    • 0007515296 scopus 로고    scopus 로고
    • Food and Drug Administration Center for Drug Evaluation and Research, March 4, Aredia/Zometa. Available from, Accessed 4 April 2012
    • Food and Drug Administration Center for Drug Evaluation and Research. Oncologic Drugs Advisory Committee Meeting: March 4, 2005. Aredia/Zometa. Available from: www.fda.gov. Accessed 4 April 2012.
    • (2005) Oncologic Drugs Advisory Committee Meeting
  • 30
    • 10744233021 scopus 로고    scopus 로고
    • Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: A randomized, double-blind, multicenter, comparative trial
    • Rosen LS, Gordon D, Kaminski M, etal. Long-term efficacy and safety of zoledronic acid compared with pamidronate disodium in the treatment of skeletal complications in patients with advanced multiple myeloma or breast carcinoma: a randomized, double-blind, multicenter, comparative trial. Cancer. 2003;98(8):1735-1744.
    • (2003) Cancer. , vol.98 , Issue.8 , pp. 1735-1744
    • Rosen, L.S.1    Gordon, D.2    Kaminski, M.3    et al4
  • 31
    • 79551568488 scopus 로고    scopus 로고
    • Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: A randomized, double-blind study
    • Stopeck AT, Lipton A, Body JJ, etal. Denosumab compared with zoledronic acid for the treatment of bone metastases in patients with advanced breast cancer: a randomized, double-blind study. J Clin Oncol. 2010;28(35):5132-5139.
    • (2010) J Clin Oncol. , vol.28 , Issue.35 , pp. 5132-5139
    • Stopeck, A.T.1    Lipton, A.2    Body, J.J.3    et al4
  • 32
    • 79952743744 scopus 로고    scopus 로고
    • American Society of Clinical Oncology executive summary of the clinical practice guideline update on the role of bone-modifying agents in metastatic breast cancer
    • Van Poznak CH, Temin S, Yee GC, etal. American Society of Clinical Oncology executive summary of the clinical practice guideline update on the role of bone-modifying agents in metastatic breast cancer. J Clin Oncol. 2011;29(9):1221-1227.
    • (2011) J Clin Oncol. , vol.29 , Issue.9 , pp. 1221-1227
    • van Poznak, C.H.1    Temin, S.2    Yee, G.C.3    et al4
  • 34
    • 0031003458 scopus 로고    scopus 로고
    • Chemical castration induced by adjuvant cyclophosphamide, methotrexate, and fluorouracil chemotherapy causes rapid bone loss that is reduced by clodronate: A randomized study in premenopausal breast cancer patients
    • Saarto T, Blomqvist C, Valimaki M, Makela P, Sarna S, Elomaa I. Chemical castration induced by adjuvant cyclophosphamide, methotrexate, and fluorouracil chemotherapy causes rapid bone loss that is reduced by clodronate: a randomized study in premenopausal breast cancer patients. J Clin Oncol. 1997;15(4):1341-1347.
    • (1997) J Clin Oncol. , vol.15 , Issue.4 , pp. 1341-1347
    • Saarto, T.1    Blomqvist, C.2    Valimaki, M.3    Makela, P.4    Sarna, S.5    Elomaa, I.6
  • 35
    • 69049083492 scopus 로고    scopus 로고
    • Denosumab for prevention of fractures in postmenopausal women with osteoporosis
    • Cummings SR, San Martin J, McClung MR, etal. Denosumab for prevention of fractures in postmenopausal women with osteoporosis. N Engl J Med. 2009;361(8):756-765.
    • (2009) N Engl J Med. , vol.361 , Issue.8 , pp. 756-765
    • Cummings, S.R.1    San Martin, J.2    McClung, M.R.3    et al4
  • 36
    • 54449084015 scopus 로고    scopus 로고
    • Randomized trial of denosumab in patients receiving adjuvant aromatase inhibitors for nonmetastatic breast cancer
    • Ellis GK, Bone HG, Chlebowski R, etal. Randomized trial of denosumab in patients receiving adjuvant aromatase inhibitors for nonmetastatic breast cancer. J Clin Oncol. 2008;26(30):4875-4882.
    • (2008) J Clin Oncol. , vol.26 , Issue.30 , pp. 4875-4882
    • Ellis, G.K.1    Bone, H.G.2    Chlebowski, R.3    et al4
  • 37
    • 34247866550 scopus 로고    scopus 로고
    • Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis
    • for HORIZON Pivotal Fracture Trial
    • Black DM, Delmas PD, Eastell R, etal; for HORIZON Pivotal Fracture Trial. Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. N Engl J Med. 2007;356(18):1809-1822.
    • (2007) N Engl J Med. , vol.356 , Issue.18 , pp. 1809-1822
    • Black, D.M.1    Delmas, P.D.2    Eastell, R.3    et al4
  • 38
    • 84857370664 scopus 로고    scopus 로고
    • Final 5-year results of Z-FAST trial: Adjuvant zoledronic acid maintains bone mass in postmenopausal breast cancer patients receiving letrozole
    • Brufsky AM, Harker WG, Beck JT, etal. Final 5-year results of Z-FAST trial: adjuvant zoledronic acid maintains bone mass in postmenopausal breast cancer patients receiving letrozole. Cancer. 2012;118(5):1192-1201.
    • (2012) Cancer. , vol.118 , Issue.5 , pp. 1192-1201
    • Brufsky, A.M.1    Harker, W.G.2    Beck, J.T.3    et al4
  • 39
    • 77954580167 scopus 로고    scopus 로고
    • Efficacy of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36-month results of the ZO-FAST Study
    • Eidtmann H, de Boer R, Bundred N, etal. Efficacy of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: 36-month results of the ZO-FAST Study. Ann Oncol. 2010;21(11):2188-2194.
    • (2010) Ann Oncol. , vol.21 , Issue.11 , pp. 2188-2194
    • Eidtmann, H.1    de Boer, R.2    Bundred, N.3    et al4
  • 40
    • 84862926420 scopus 로고    scopus 로고
    • Immediate administration of zoledronic acid reduces aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer: 12-month analysis of the E-ZO-FAST trial
    • Llombart A, Frassoldati A, Paija O, etal. Immediate administration of zoledronic acid reduces aromatase inhibitor-associated bone loss in postmenopausal women with early breast cancer: 12-month analysis of the E-ZO-FAST trial. Clin Breast Cancer. 2012;12(1):40-48.
    • (2012) Clin Breast Cancer. , vol.12 , Issue.1 , pp. 40-48
    • Llombart, A.1    Frassoldati, A.2    Paija, O.3    et al4
  • 41
    • 61449227421 scopus 로고    scopus 로고
    • Phase III randomized, placebo-controlled, double-blind trial of risedronate for the prevention of bone loss in premenopausal women undergoing chemotherapy for primary breast cancer
    • Hines SL, Mincey BA, Sloan JA, etal. Phase III randomized, placebo-controlled, double-blind trial of risedronate for the prevention of bone loss in premenopausal women undergoing chemotherapy for primary breast cancer. J Clin Oncol. 2009;27(7):1047-1053.
    • (2009) J Clin Oncol. , vol.27 , Issue.7 , pp. 1047-1053
    • Hines, S.L.1    Mincey, B.A.2    Sloan, J.A.3    et al4
  • 42
    • 84857637022 scopus 로고    scopus 로고
    • Zoledronic acid in the treatment of early-stage breast cancer: Is there a final verdict
    • Gnant M. Zoledronic acid in the treatment of early-stage breast cancer: is there a final verdict? Curr Oncol Rep. 2012;14(1):35-43.
    • (2012) Curr Oncol Rep. , vol.14 , Issue.1 , pp. 35-43
    • Gnant, M.1
  • 43
    • 84870541156 scopus 로고    scopus 로고
    • Cost-effectiveness of zoledronic acid plus endocrine therapy in premenopausal women with early stage breast cancer (BC) enrolled in the ABCSG-12study [poster]
    • May 7-9, Brussels, Belgium. Abstract 73P
    • Gnant MF, Kaura S, Sofrygin O, Delea TE. Cost-effectiveness of zoledronic acid plus endocrine therapy in premenopausal women with early stage breast cancer (BC) enrolled in the ABCSG-12study [poster]. Presented at: IMPAKT-Breast Cancer Conference; May 7-9, 2009; Brussels, Belgium. Abstract 73P.
    • (2009) Presented at: IMPAKT-Breast Cancer Conference
    • Gnant, M.F.1    Kaura, S.2    Sofrygin, O.3    Delea, T.E.4
  • 44
    • 80052734955 scopus 로고    scopus 로고
    • New perspectives on zoledronic acid in breast cancer: Potential augmentation of anticancer immune response
    • Hamilton E, Clay TM, Blackwell KL. New perspectives on zoledronic acid in breast cancer: potential augmentation of anticancer immune response. Cancer Invest. 2011;29(8):533-541.
    • (2011) Cancer Invest. , vol.29 , Issue.8 , pp. 533-541
    • Hamilton, E.1    Clay, T.M.2    Blackwell, K.L.3
  • 45
    • 78649718114 scopus 로고    scopus 로고
    • Cost-effectiveness of zoledronic acid (ZOL) for the treatment of bone loss in postmenopausal women with early-stage breast cancer receiving aromatase inhibitors in the United States (US)
    • Abstract e11007
    • Thurston SJ, Zelt SC, Botteman M. Cost-effectiveness of zoledronic acid (ZOL) for the treatment of bone loss in postmenopausal women with early-stage breast cancer receiving aromatase inhibitors in the United States (US). J Clin Oncol. 2010;28(Suppl):Abstract e11007.
    • (2010) J Clin Oncol. , vol.28 , Issue.SUPPL.
    • Thurston, S.J.1    Zelt, S.C.2    Botteman, M.3
  • 46
    • 46949100735 scopus 로고    scopus 로고
    • Exploring the anti-tumour activity of bisphosphonates in early breast cancer
    • Winter MC, Holen I, Coleman RE. Exploring the anti-tumour activity of bisphosphonates in early breast cancer. Cancer Treat Rev. 2008; 34(5):453-475.
    • (2008) Cancer Treat Rev. , vol.34 , Issue.5 , pp. 453-475
    • Winter, M.C.1    Holen, I.2    Coleman, R.E.3
  • 47
    • 84870495730 scopus 로고    scopus 로고
    • Number needed to treat and treatment cost per fracture avoided with denosumab compared with zoledronic acid in patients with breast cancer with bone metastases [poster]
    • September 8-10, San Francisco, CA. Abstract 151
    • Wu EQ, Xie J, Signorovitch J, Diener M, Sorg R, Namjoshi M. Number needed to treat and treatment cost per fracture avoided with denosumab compared with zoledronic acid in patients with breast cancer with bone metastases [poster]. Presented at: 2011ASCO Breast Cancer Symposium; September 8-10, 2011; San Francisco, CA. Abstract 151.
    • (2011) Presented at: 2011ASCO Breast Cancer Symposium
    • Wu, E.Q.1    Xie, J.2    Signorovitch, J.3    Diener, M.4    Sorg, R.5    Namjoshi, M.6
  • 48
    • 84859101303 scopus 로고    scopus 로고
    • The role of antiresorptive therapies in improving patient care in early and metastatic breast cancer
    • Candelaria-Quintana D, Dayao ZR, Royce ME. The role of antiresorptive therapies in improving patient care in early and metastatic breast cancer. Breast Cancer Res Treat. 2012;132(2):355-363.
    • (2012) Breast Cancer Res Treat. , vol.132 , Issue.2 , pp. 355-363
    • Candelaria-Quintana, D.1    Dayao, Z.R.2    Royce, M.E.3
  • 49
    • 60549097419 scopus 로고    scopus 로고
    • Endocrine therapy plus zoledronic acid in premenopausal breast cancer
    • for ABSCG-12 Trial Investigators
    • Gnant M, Mlineritsch B, Schippinger W, etal; for ABSCG-12 Trial Investigators. Endocrine therapy plus zoledronic acid in premenopausal breast cancer. N Engl J Med. 2009;360(7):679-691.
    • (2009) N Engl J Med. , vol.360 , Issue.7 , pp. 679-691
    • Gnant, M.1    Mlineritsch, B.2    Schippinger, W.3    et al4
  • 50
    • 84857099998 scopus 로고    scopus 로고
    • Long-term follow-up in ABCSG-12: Significantly improved overall survival with adjuvant zoledronic acid in premenopausal patients with hormone-receptor-positive early breast cancer [oral]
    • December 6-10, San Antonio, TX. Abstract S1-S2
    • Gnant M, Mlineritsch B, Luschin-Ebengreuth G, etal. Long-term follow-up in ABCSG-12: significantly improved overall survival with adjuvant zoledronic acid in premenopausal patients with hormone-receptor-positive early breast cancer [oral]. Presented at: 2011 CTRC-AACR San Antonio Breast Cancer Symposium; December 6-10, 2011; San Antonio, TX. Abstract S1-S2.
    • (2011) Presented at: 2011 CTRC-AACR San Antonio Breast Cancer Symposium
    • Gnant, M.1    Mlineritsch, B.2    Luschin-Ebengreuth, G.3
  • 51
    • 52049103847 scopus 로고    scopus 로고
    • The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance
    • Meads MB, Hazlehurst LA, Dalton WS. The bone marrow microenvironment as a tumor sanctuary and contributor to drug resistance. Clin Cancer Res. 2008;14(9):2519-2526.
    • (2008) Clin Cancer Res. , vol.14 , Issue.9 , pp. 2519-2526
    • Meads, M.B.1    Hazlehurst, L.A.2    Dalton, W.S.3
  • 52
    • 43749115751 scopus 로고    scopus 로고
    • The bone marrow niche: Habitat to hematopoietic and mesenchymal stem cells, and unwitting host to molecular parasites
    • Shiozawa Y, Havens AM, Pienta KJ, Taichman RS. The bone marrow niche: habitat to hematopoietic and mesenchymal stem cells, and unwitting host to molecular parasites. Leukemia. 2008;22(5):941-950.
    • (2008) Leukemia. , vol.22 , Issue.5 , pp. 941-950
    • Shiozawa, Y.1    Havens, A.M.2    Pienta, K.J.3    Taichman, R.S.4
  • 53
    • 77955497101 scopus 로고    scopus 로고
    • Current and emerging concepts in tumour metastasis
    • Coghlin C, Murray GI. Current and emerging concepts in tumour metastasis. J Pathol. 2010;222(1):1-15.
    • (2010) J Pathol. , vol.222 , Issue.1 , pp. 1-15
    • Coghlin, C.1    Murray, G.I.2
  • 54
    • 77952305169 scopus 로고    scopus 로고
    • Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: An open label, randomised, phase 2 trial
    • Aft R, Naughton M, Trinkaus K, etal. Effect of zoledronic acid on disseminated tumour cells in women with locally advanced breast cancer: an open label, randomised, phase 2 trial. Lancet Oncol. 2010;11(5):421-428.
    • (2010) Lancet Oncol. , vol.11 , Issue.5 , pp. 421-428
    • Aft, R.1    Naughton, M.2    Trinkaus, K.3    et al4
  • 55
    • 61349156290 scopus 로고    scopus 로고
    • Zoledronic acid as adjuvant therapy for women with early stage breast cancer and disseminated tumor cells in bone marrow [abstract]
    • Abstract 559
    • Lin AY, Park JW, Scott J, etal. Zoledronic acid as adjuvant therapy for women with early stage breast cancer and disseminated tumor cells in bone marrow [abstract]. J Clin Oncol. 2008;26(Suppl):20s. Abstract 559.
    • (2008) J Clin Oncol. , vol.26 , Issue.SUPPL.
    • Lin, A.Y.1    Park, J.W.2    Scott, J.3    et al4
  • 56
    • 77954572691 scopus 로고    scopus 로고
    • Effect of zoledronate on persisting isolated tumour cells in patients with early breast cancer
    • Rack B, Juckstock J, Genss EM, etal. Effect of zoledronate on persisting isolated tumour cells in patients with early breast cancer. Anticancer Res. 2010;30(5):1807-1813.
    • (2010) Anticancer Res. , vol.30 , Issue.5 , pp. 1807-1813
    • Rack, B.1    Juckstock, J.2    Genss, E.M.3    et al4
  • 57
    • 78649267109 scopus 로고    scopus 로고
    • Influence of zoledronic acid on disseminated tumor cells (DTC) in primary breast cancer patients [poster]
    • December 10-14, San Antonio, TX. Abstract 2048
    • Solomayer EF, Gebauer G, Hirnle P, etal. Influence of zoledronic acid on disseminated tumor cells (DTC) in primary breast cancer patients [poster]. Presented at: 31st Annual San Antonio Breast Cancer Symposium; December 10-14, 2008; San Antonio, TX. Abstract 2048.
    • (2008) Presented at: 31st Annual San Antonio Breast Cancer Symposium
    • Solomayer, E.F.1    Gebauer, G.2    Hirnle, P.3
  • 58
    • 72249093615 scopus 로고    scopus 로고
    • Tumor self-seeding by circulating cancer cells
    • Kim MY, Oskarsson T, Acharyya S, etal. Tumor self-seeding by circulating cancer cells. Cell. 2009;139(7):1315-1326.
    • (2009) Cell. , vol.139 , Issue.7 , pp. 1315-1326
    • Kim, M.Y.1    Oskarsson, T.2    Acharyya, S.3    et al4
  • 59
    • 80054035939 scopus 로고    scopus 로고
    • Breast-cancer adjuvant therapy with zoledronic acid
    • for AZURE Investigators
    • Coleman RE, Marshall H, Cameron D, etal; for AZURE Investigators. Breast-cancer adjuvant therapy with zoledronic acid. N Engl J Med. 2011;365(15):1396-1405.
    • (2011) N Engl J Med. , vol.365 , Issue.15 , pp. 1396-1405
    • Coleman, R.E.1    Marshall, H.2    Cameron, D.3    et al4
  • 60
    • 79959565208 scopus 로고    scopus 로고
    • Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 62-month follow-up from the ABCSG-12 randomised trial
    • for Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria
    • Gnant M, Mlineritsch B, Stoeger H, etal; for Austrian Breast and Colorectal Cancer Study Group, Vienna, Austria. Adjuvant endocrine therapy plus zoledronic acid in premenopausal women with early-stage breast cancer: 62-month follow-up from the ABCSG-12 randomised trial. Lancet Oncol. 2011;12(7):631-641.
    • (2011) Lancet Oncol. , vol.12 , Issue.7 , pp. 631-641
    • Gnant, M.1    Mlineritsch, B.2    Stoeger, H.3    et al4
  • 61
    • 44449153039 scopus 로고    scopus 로고
    • Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates
    • Hoff AO, Toth BB, Altundag K, etal. Frequency and risk factors associated with osteonecrosis of the jaw in cancer patients treated with intravenous bisphosphonates. J Bone Miner Res. 2008;23(6):826-836.
    • (2008) J Bone Miner Res. , vol.23 , Issue.6 , pp. 826-836
    • Hoff, A.O.1    Toth, B.B.2    Altundag, K.3    et al4
  • 62
    • 58949093771 scopus 로고    scopus 로고
    • Decreased occurrence of osteonecrosis of the jaw after implementation of dental preventive measures in solid tumour patients with bone metastases treated with bisphosphonates
    • The experience of the National Cancer Institute of Milan
    • Ripamonti CI, Maniezzo M, Campa T, etal. Decreased occurrence of osteonecrosis of the jaw after implementation of dental preventive measures in solid tumour patients with bone metastases treated with bisphosphonates. The experience of the National Cancer Institute of Milan. Ann Oncol. 2009;20(1):137-145.
    • (2009) Ann Oncol. , vol.20 , Issue.1 , pp. 137-145
    • Ripamonti, C.I.1    Maniezzo, M.2    Campa, T.3    et al4
  • 63
    • 58049204529 scopus 로고    scopus 로고
    • Natural history of osteonecrosis of the jaw in patients with multiple myeloma
    • Badros A, Terpos E, Katodritou E, etal. Natural history of osteonecrosis of the jaw in patients with multiple myeloma. J Clin Oncol. 2008;26(36):5904-5909.
    • (2008) J Clin Oncol. , vol.26 , Issue.36 , pp. 5904-5909
    • Badros, A.1    Terpos, E.2    Katodritou, E.3    et al4
  • 64
    • 77955552044 scopus 로고    scopus 로고
    • Impact of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST, ZO-FAST, and E-ZO-FAST [poster]
    • December 9-13, San Antonio, TX. Abstract 4082
    • Coleman R, Bundred N, de Boer R, etal. Impact of zoledronic acid in postmenopausal women with early breast cancer receiving adjuvant letrozole: Z-FAST, ZO-FAST, and E-ZO-FAST [poster]. Presented at: 32nd Annual San Antonio Breast Cancer Symposium; December 9-13, 2009; San Antonio, TX. Abstract 4082.
    • (2009) Presented at: 32nd Annual San Antonio Breast Cancer Symposium
    • Coleman, R.1    Bundred, N.2    de Boer, R.3
  • 65
    • 78649502301 scopus 로고    scopus 로고
    • Payer costs for inpatient treatment of pathologic fracture, surgery to bone, and spinal cord compression among patients with multiple myeloma or bone metastasis secondary to prostate or breast cancer
    • Barlev A, Song X, Ivanov B, Setty V, Chung K. Payer costs for inpatient treatment of pathologic fracture, surgery to bone, and spinal cord compression among patients with multiple myeloma or bone metastasis secondary to prostate or breast cancer. J Manag Care Pharm. 2010;16(9):693-702.
    • (2010) J Manag Care Pharm. , vol.16 , Issue.9 , pp. 693-702
    • Barlev, A.1    Song, X.2    Ivanov, B.3    Setty, V.4    Chung, K.5
  • 66
    • 1642453605 scopus 로고    scopus 로고
    • A retrospective analysis of health care costs for bone fractures in women with early-stage breast carcinoma
    • Zhou Z, Redaelli A, Johnell O, Willke RJ, Massimini G. A retrospective analysis of health care costs for bone fractures in women with early-stage breast carcinoma. Cancer. 2004;100(3):507-517.
    • (2004) Cancer. , vol.100 , Issue.3 , pp. 507-517
    • Zhou, Z.1    Redaelli, A.2    Johnell, O.3    Willke, R.J.4    Massimini, G.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.