Caveolin-1 regulates neural differentiation of rat bone mesenchymal stem cells into neurons by modulating Notch signaling

International Journal of Developmental Neuroscience

Volumn 31, Issue 1, 2013, Pages 30-35

  Wang, Shuyang ^a   Kan, Quancheng ^a   Sun, Yingpu ^a   Han, Rui ^a   Zhang, Guangyu ^a   Peng, Tao ^a   Jia, Yanjie ^a  

^a THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

Author keywords

Caveolin 1; Differentiation; Hes5; MSCs; Neuron; NICD; Notch 1

Indexed keywords

BIOLOGICAL MARKER; CAVEOLIN 1; MICROTUBULE ASSOCIATED PROTEIN 2; NEURON SPECIFIC ENOLASE; NOTCH RECEPTOR; NOTCH1 RECEPTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; GENE SILENCING; GENETIC TRANSFECTION; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; INTRACELLULAR SIGNALING; MESENCHYMAL STEM CELL; NERVE CELL DIFFERENTIATION; NEUROMODULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN PROTEIN INTERACTION; RAT; UPREGULATION;

ANIMALS; BONE MARROW CELLS; CAVEOLIN 1; CELL DIFFERENTIATION; CELLS, CULTURED; GENE EXPRESSION REGULATION; MERCAPTOETHANOL; MESENCHYMAL STROMAL CELLS; MICROTUBULE-ASSOCIATED PROTEINS; NEURONS; PHOSPHOPYRUVATE HYDRATASE; RATS; RATS, WISTAR; RECEPTORS, NOTCH; RNA, MESSENGER; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

RATTUS;

EID: 84870483323     PISSN: 07365748     EISSN: 1873474X     Source Type: Journal    
DOI: 10.1016/j.ijdevneu.2012.09.004     Document Type: Article

References (48)

1. Artavanis-Tsakonas S., Delidakis C., Fehon R.G. The Notch locus and the cell biology of neuroblast segregation. Annual Review of Cell Biology 1991, 7:427-452.
2. Artavanis-Tsakonas S., Rand M.D., Lake R.J. Notch signaling: cell fate control and signal integration in development. Science 1999, 284:770-776.
3. Baksh D., Song L., Tuan R.S. Adult mesenchymal stem cells: characterization, differentiation and application in cell and gene therapy. Journal of Cellular and Molecular Medicine 2004, 8:301-316.
4. Bertani N., Malatesta P., Volpi G., Sonego P., Perris R. Neurogenic potential of human mesenchymal stem cells revisited: analysis by immunostaining, time-lapse video and microarray. Journal of Cell Science 2005, 118:3925-3936.
5. Bianco P., Robey P.G., Simmons P.J. Mesenchymal stem cells: revisiting history, concepts, and assays. Cell Stem Cell 2008, 2:313-319.
6. Blaumueller C.M., Qi H., Zagouras P., Artavanis-Tsakonas S. Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane. Cell 1997, 90:281-291.
7. Campos L.S., Decker L., Taylor V., Skarnes W. Notch, epidermal growth factor receptor, and beta1-integrin pathways are coordinated in neural stem cells. Journal of Biological Chemistry 2006, 281:5300-5309.
8. Chun M., Liyanage U.K., Lisanti M.P., Lodish H.F. Signal transduction of a G protein-coupled receptor in caveolae: colocalization of endothelin and its receptor with caveolin. Proceedings of the National Academy of Sciences of the United States of America 1994, 91:11728-11732.
9. del Pozo M.A., Balasubramanian N., Alderson N.B., Kiosses W.B., Grande-García A., Anderson R.G., Schwartz M.A. Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization. Nature Cell Biology 2005, 7:901-908.
10. Du J., Chen X., Liang X., Zhang G., Xu J., He L., Zhan Q., Feng X.Q., Chien S., Yang C. Integrin activation and internalization on soft ECM as a mechanism of induction of stem cell differentiation by ECM elasticity. Proceedings of the National Academy of Sciences of the United States of America 2011, 108:9466-9471.
11. Engelman J.A., Wykoff C.C., Yasuhara S., Song K.S., Okamoto T., Lisanti M.P. Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth. Journal of Biological Chemistry 1997, 272:16374-16381.
12. Frank P.G., Pavlides S., Cheung M.W., Daumer K., Lisanti M.P. Role of caveolin-1 in the regulation of lipoprotein metabolism. American Journal of Physiology Cell Physiology 2008, 295:242-248.
13. Fujimoto T., Kogo H., Nomura R., Une T. Isoforms of caveolin-1 and caveolar structure. Journal of Cell Science 2000, 113:3017-3509.
14. Gaiano N., Fishell G. The role of notch in promoting glial and neural stem cell fates role of notch in promoting glial. Annual Review of Neuroscience 2002, 25:471-490.
15. Galbiati F., Volonte D., Gil O., Zanazzi G., Salzer J.L., Sargiacomo M., Scherer P.E., Engelman J.A., Schlegel A., Parenti M., Okamoto T., Lisanti M.P. Expression of caveolin-1 and -2 in differentiating PC12 cells and dorsal root ganglion neurons: caveolin-2 is up-regulated in response to cell injury. Proceedings of the National Academy of Sciences of the United States of America 1998, 95:10257-10262.
16. Glenney J.R., Soppet D. Sequence and expression of caveolin, a protein component of caveolae plasma membrane domains phosphorylated on tyrosine in Rous sarcoma virus-transformed fibroblasts. Proceedings of the National Academy of Sciences of the United States of America 1992, 89:10517-10521.
17. Grande-García A., Echarri A., de Rooij J., Alderson N.B., Waterman-Storer C.M., Valdivielso J.M., del Pozo M.A. Caveolin-1 regulates cell polarization and directional migration through Src kinase and Rho GTPases. Journal of Cell Biology 2007, 177:683-694.
18. Hämmerle B., Tejedor F.J. A novel function of DELTA-NOTCH signalling mediates the transition from proliferation to neurogenesis in neural progenitor cells. PLoS ONE 2007, 2:1169.
19. Head B.P., Peart J.N., Panneerselvam M., Yokoyama T., Pearn M.L., Niesman I.R., Bonds J.A., Schilling J.M., Miyanohara A., Headrick J., Ali S.S., Roth D.M., Patel P.M., Patel H.H. Loss of caveolin-1 accelerates neurodegeneration and aging. PLoS ONE 2010, 5:15697.
20. Ikezu T., Ueda H., Trapp B.D., Nishiyama K., Sha J.F., Volonte D., Galbiati F., Byrd A.L., Bassell G., Serizawa H., Lane W.S., Lisanti M.P., Okamoto T. Affinity-purification and characterization of caveolins from the brain: differential expression of caveolin-1, -2, and -3 in brain endothelial and astroglial cell types. Brain Research 1998, 804:177-192.
21. Jasmin J.F., Yang M., Iacovitti L., Lisanti M.P. Genetic ablation of caveolin-1 increases neural stem cell proliferation in the subventricular zone (SVZ) of the adult mouse brain. Cell Cycle 2009, 8:3978-3983.
22. Jing L., Jia Y., Lu J., Han R., Li J., Wang S., Peng T., Jia Y. MicroRNA-9 promotes differentiation of mouse bone mesenchymal stem cells into neurons by Notch signaling. Neuroreport 2011, 22:206-211.
23. Krampera M., Cosmi L., Angeli R., Pasini A., Liotta F., Andreini A., Santarlasci V., Mazzinghi B., Pizzolo G., Vinante F., Romagnani P., Maggi E., Romagnani S., Annunziato F. Role of the IFN-γ in the immunomodulatory activity of human mesenchymal stem cells. Stem Cells 2005, 24:386-398.
24. Krampera M., Marconi S., Pasini A., Galiè M., Rigotti G., Mosna F., Tinelli M., Lovato L., Anghileri E., Andreini A., Pizzolo G., Sbarbati A., Bonetti B. Induction of neural-like differentiation in human mesenchymal stem cells derived from bone marrow, fat, spleen and thymus. Bone 2007, 40:382-390.
25. Lee M.Y., Lee S.H., Park J.H., Han H.J. Interaction of galectin-1 with caveolae induces mouse embryonic stem cell proliferation through the Src, ERas, Akt and mTOR signaling pathways. Cellular and Molecular Life Sciences 2009, 66:1467-1478.
26. Li Y., Lau W.M., So K.F., Tong Y., Shen J. Caveolin-1 promote astroglial differentiation of neural stem/progenitor cells through modulating Notch1/NICD and Hes1 expressions. Biochemical and Biophysical Research Communications 2011, 407:517-524.
27. Li Y., Luo J., Lau W.M., Zheng G., Fu S., Wang T.T., Zeng H.P., So K.F., Chung S.K., Tong Y., Liu K., Shen J. Caveolin-1 plays a crucial role in inhibiting neuronal differentiation of neural stem/progenitor cells via VEGF signaling-dependent Pathway. PLoS ONE 2011, 6:22901.
28. Liu J., Sato C., Cerletti M., Wagers A. Notch signaling in the regulation of stem cell self-renewal and differentiation. Current Topics in Developmental Biology 2010, 92:367-409.
29. Mineo C., Ying Y.S., Chapline C., Jaken S., Anderson R.G. Targeting of protein kinase Calpha to caveolae. Journal of Cell Biology 1998, 141:601-610.
30. Ohtsuka T., Sakamoto M., Guillemot F., Kageyama R. Roles of the basic helix-loop-helix genes Hes1 and Hes5 in expansion of neural stem cells of the developing brain. Journal of Biological Chemistry 2001, 276:30467-3046774.
31. Parat M.O., Anand-Apte B., Fox P.L. Differential caveolin-1 polarization in endothelial cells during migration in two and three dimensions. Molecular Biology of the Cell 2003, 14:3156-3168.
32. Park J.H., Han H.J. Caveolin-1 plays important role in EGF-induced migration and proliferation of mouse embryonic stem cell involvement of PI3K/Akt and ERK. American Journal of Physiology Cell Physiology 2009, 297:935-944.
33. Park J.S., Kim H.Y., Kim H.W., Chae G.N., Oh H.T., Park J.Y., Shim H., Seo M., Shin E.Y., Kim E.G., Park S.C., Kwak S.J. Increased caveolin-1, a cause for the declined adipogenic potential of senescent human mesenchymal stem cells. Mechanisms of Ageing and Development 2005, 126:551-559.
34. Parton R.G., Simons K. The multiple faces of caveolae. Nature Reviews Molecular Cell Biology 2007, 8:185-194.
35. Pittenger M.F., Mackay A.M., Beck S.C., Jaiswal R.K., Douglas R., Mosca J.D., Moorman M.A., Simonetti D.W., Craig S., Marshak D.R. Multilineage potential of adult human mesenchymal stem cells. Science 1999, 284:143-147.
36. Razani B., Woodman S.E., Lisanti M.P. Caveolae: from cell biology to animal physiology. Pharmacological Reviews 2002, 54:431-467.
37. Salani B., Briatore L., Garibaldi S., Cordera R., Maggi D. Caveolin-1 down-regulation inhibits insulin-like growth factor-I receptor signal transduction in H9C2 rat cardiomyoblasts. Endocrinology 2008, 149:461-465.
38. Sanchez-Ramos J.R. Neural cells derived from adult bone marrow and umbilical cord blood. Journal of Neuroscience Research 2002, 69:880-893.
39. Sanchez-Ramos J., Song S., Cardozo-Pelaez F., Hazzi C., Stedeford T., Willing A., Freeman T.B., Saporta S., Janssen W., Patel N., Cooper D.R., Sanberg P.R. Adult bone marrow stromal cells differentiate into neural cells in vitro. Experimental Neurology 2000, 164:247-256.
40. Scherer P.E., Okamoto T., Chun M., Nishimoto I., Lodish H.F., Lisanti M.P. Identification, sequence, and expression of caveolin-2 defines a caveolin gene family. Proceedings of the National Academy of Sciences of the United States of America 1996, 93:131-135.
41. Scherer P.E., Lewis R.Y., Volonte D., Engelman J.A., Galbiati F., Couet J., Kohtz D.S., van Donselaar E., Peters P., Lisanti M.P. Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo. Journal of Biological Chemistry 1997, 272:29337-29346.
42. Song K.S., Li Shengwen Okamoto T., Quilliam L.A., Sargiacomo M., Lisanti M.P. Co-purification and direct interaction of Ras with caveolin, an integral membrane protein of caveolae microdomains. Detergent-free purification of caveolae microdomains. Journal of Biological Chemistry 1996, 271:9690-9697.
43. Wheeler S.R., Stagg S.B., Crews S.T. Multiple Notch signaling events control Drosophila CNS midline neurogenesis, gliogenesis and neuronal identity. Development 2008, 135:3071-3079.
44. Williams T.M., Lisanti M.P. Caveolin-1 in oncogenic transformation, cancer, and metastasis. American Journal of Physiology Cell Physiology 2005, 288:494-506.
45. Woo S.M., Kim J., Han H.W., Chae J.I., Son M.Y., Cho S., Chung H.M., Han Y.M., Kang Y.K. Notch signaling is required for maintaining stem-cell features of neuroprogenitor cells derived from human embryonic stem cells. BMC Neuroscience 2009, 10:97.
46. Woodbury D., Schwarz E.J., Prockop D.J., Black I.B. Adult rat and human bone marrow stromal cells differentiate into neurons. Journal of Neuroscience Research 2000, 61:364-370.
47. Yanjie J., Jiping S., Yan Z., Xiaofeng Z., Boai Z., Yajun L. Effects of Notch-1 signaling pathway on differentiation of marrow mesenchymal stem cells into neurons in vitro. Neuroreport 2007, 18:1443-1447.
48. Yoon K., Gaiano N. Notch signaling in the mammalian central nervous system: insights from mouse mutants. Nature Neuroscience 2005, 8:709-715.