Reversal of diabetes in mice with a bioengineered islet implant incorporating a type I collagen hydrogel and sustained release of vascular endothelial growth factor

Cell Transplantation

Volumn 21, Issue 10, 2012, Pages 2099-2110

  Vernon, Robert B ^a   Preisinger, Anton ^a   Gooden, Michel D ^a   D'Amico, Leonard A ^a   Yue, Betty B ^a   Bollyky, Paul L ^a   Kuhr, Christian S ^b   Hefty, Thomas R ^b   Nepom, Gerald T ^a   Gebe, John A ^a  

^a BENAROYA RESEARCH INSTITUTE   (United States)

^b VIRGINIA MASON MEDICAL CENTER   (United States)

Author keywords

Bioengineered implant (BI); Collagen; Diabetes; Islet; Mouse; Vascular endothelial growth factor (VEGF)

Indexed keywords

COLLAGEN TYPE 1; GLUCOSE; INSULIN DETEMIR; POLYVINYL ALCOHOL SPONGE; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOENGINEERED ISLET IMPLANT; BIOENGINEERING; CELL VIABILITY; CONTROLLED STUDY; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; GRAFT SURVIVAL; HISTOLOGY; HYDROGEL; HYPOGLYCEMIA; IMPLANT; INSULIN TREATMENT; MOUSE; NONHUMAN; PANCREAS ISLET CELL; PANCREAS ISLET TRANSPLANTATION; PRIORITY JOURNAL; STREPTOZOCIN DIABETES; TREATMENT RESPONSE;

ANIMALS; COLLAGEN TYPE I; DELAYED-ACTION PREPARATIONS; DIABETES MELLITUS, EXPERIMENTAL; DISEASE MODELS, ANIMAL; HYDROGEL; ISLETS OF LANGERHANS; ISLETS OF LANGERHANS TRANSPLANTATION; MICE; MICE, INBRED C57BL; TISSUE ENGINEERING; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

MUS;

EID: 84870466759     PISSN: 09636897     EISSN: None     Source Type: Journal    
DOI: 10.3727/096368912X636786     Document Type: Article

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