Hydrogen sulfide (H2S): A physiologic mediator of carotid body response to hypoxia

Advances in Experimental Medicine and Biology

Volumn 758, Issue , 2012, Pages 109-113

  Prabhakar, Nanduri R ^a  

^a University of Chicago   (United States)

Author keywords

Gasotransmitters; Glomus cells; Hypoxia

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; CYSTATHIONINE BETA SYNTHASE; CYSTATHIONINE GAMMA LYASE; HYDROGEN SULFIDE; VOLTAGE GATED CALCIUM CHANNEL;

CALCIUM SIGNALING; CALCIUM TRANSPORT; CAROTID BODY; CELL HYPOXIA; CELLULAR PARAMETERS; CELLULAR STRESS RESPONSE; CELLULAR TARGET; CONFERENCE PAPER; ENZYME INHIBITION; HYPOXIC VENTILATORY RESPONSE; METABOLIC PARAMETERS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

EID: 84870443875     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-94-007-4584-1_15     Document Type: Conference Paper

References (22)

1. Abeles RH, Walsh CT (1973) Acetylenic enzyme inactivators. Inactivation of g -cystathionase, in vitro and in vivo, by propargylglycine. J Am Chem Soc 95:6124-6125
2. Campanucci VA, Nurse CA (2007) Autonomic innervation of the carotid body: Role in efferent inhibition. Respir Physiol Neurobiol 157:83-92
3. Chugh DK, Katayama M, Mokashi A, Bebout DE, Ray DK, Lahiri S (1994) Nitric oxide related inhibition of carotid chemosensory nerve activity in the cat. Respir Physiol 97:147-156
4. Fitzgerald RS, Shirahata M, Chang I, Kostuk E, Kiihl S (2011) The impact of hydrogen sul fi de (H2S) on neurotransmitter release from the cat carotid body. Respir Physiol Neurobiol 176:80-89
5. Gadalla MM, Snyder SH (2010) Hydrogen sul fi de as a gasotransmitter. J Neurochem 113:14-26
6. Kim D, Kim I, Papreck JR, Donnelly DF, Carroll JL (2011) Characterization of an ATP-sensitive K + channel in rat carotid body glomus cells. Respir Physiol Neurobiol 177:247-255
7. Li Q, Sun B, Wang X, Jin Z, Zhou Y, Dong L, Jiang LH, Rong W (2010) A crucial role for hydrogen sul fi de in oxygen sensing via modulating large conductance calcium-activated potassium channels. Antioxid Redox Signal 1179-1189
8. López-López JR, Pérez-García MT (2007) Oxygen sensitive Kv channels in the carotid body. Respir Physiol Neurobiol 157:65-74
9. Maines MD (1997) The heme oxygenase system: A regulator of second messenger gases. Annu Rev Pharmacol Toxicol 37:517-554
10. Nurse CA (2010) Neurotransmitter and neuromodulatory mechanisms at peripheral arterial chemoreceptors. Exp Physiol 95:657-667
11. Olson KR, Dombkowski RA, Russell MJ, Doellman MM, Head SK, Whit fi eld NL, Madden JA (2006) Hydrogen sul fi de as an oxygen sensor/transducer in vertebrate hypoxic vasoconstriction and hypoxic vasodilation. J Exp Biol 209:4011-4023
12. Peng YJ, Nanduri J, Raghuraman G, Souvannakitti D, Gadalla MM, Kumar GK, Snyder SH, Prabhakar NR (2010) H2S mediates O2 sensing in the carotid body. Proc Natl Acad Sci U S A 107:10719-10724
13. Prabhakar NR (1998) Endogenous carbon monoxide in control of respiration. Respir Physiol 114:57-64
14. Prabhakar NR (1999) NO and CO as second messengers in oxygen sensing in the carotid body. Respir Physiol 115:161-168
15. Prabhakar NR (2000) Oxygen sensing by the carotid body chemoreceptors. J Appl Physiol 88:2287-2295
16. Prabhakar NR, Kumar GK, Chang CH, Agani FA, Haxhiu MA (1993) Nitric oxide in the sensory function of the carotid body. Brain Res 625:16-22
17. Prabhakar NR, Dinerman JL, Agani FH, Snyder SH (1995) Carbon monoxide: A role in carotid body chemoreception. Proc Natl Acad Sci U S A 92:1994-1997
18. Sitdikova GF, Weiger TM, Hermann A (2010) Hydrogen sul fi de increases calcium-activated potassium (BK) channel activity of rat pituitary tumor cells. P fl ugers Archiv 459:389-397
19. Telezhkin V, Brazier SP, Cayzac SH, Wilkinson WJ, Riccardi D, Kemp PJ (2010) Mechanism of inhibition by hydrogen sul fi de of native and recombinant BKCa channels. Respir Physiol Neurobiol 172:169-178
20. Wang ZZ, Stensaas LJ, Dinger B, Fidone SJ (1995) Nitric oxide mediates chemoreceptor inhibition in the cat carotid body. Neuroscience 65:217-229
21. Washtien W, Abeles RH (1977) Mechanism of inactivation of g -cystathionase by the acetylenic substrate analogue propargylglycine. Biochemistry 16:2485-2491
22. Zhao W, Zhang J, Lu Y, Wang R (2001) The vasorelaxant effect of H2S as a novel endogenous gaseous KATP channel opener. EMBO J 20:6008-6016