Clopidogrel pharmacodynamics and pharmacokinetics in the fed and fasted state: A randomized crossover study of healthy men

Journal of Clinical Pharmacology

Volumn 52, Issue 10, 2012, Pages 1506-1515

  Hurbin, Fabrice ^a   Boulenc, Xavier ^a   Daskalakis, Nikki ^b   Farenc, Christine ^a   Taylor, Theresa ^c   Bonneau, Damien ^a   Lacreta, Frank ^d   Cheng, Sue ^b   Sultan, Eric ^a  

^a SANOFI   (France)

^b Clinical and Exploratory Pharmacology   (United States)

^c Sanofi aventis Research and Development   (United States)

^d BRISTOL MYERS SQUIBB   (United States)

Author keywords

Clopidogrel; food; pharmacokinetics; platelet aggregation

Indexed keywords

ADENOSINE DIPHOSPHATE; CLOPIDOGREL; PLACEBO;

ADULT; ANALYTIC METHOD; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DIET RESTRICTION; DIETARY INTAKE; DRUG POTENCY; HUMAN; HUMAN EXPERIMENT; LIPID DIET; LIQUID CHROMATOGRAPHY; LOADING DRUG DOSE; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; TANDEM MASS SPECTROMETRY; THROMBOCYTE AGGREGATION; THROMBOCYTE AGGREGATION INHIBITION; TREATMENT DURATION;

ADENOSINE DIPHOSPHATE; ADULT; AREA UNDER CURVE; ARYL HYDROCARBON HYDROXYLASES; BREAKFAST; CROSS-OVER STUDIES; DIET, HIGH-FAT; FOOD-DRUG INTERACTIONS; GENOTYPE; HUMANS; MALE; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; TICLOPIDINE; YOUNG ADULT;

EID: 84870438675     PISSN: 00912700     EISSN: 15524604     Source Type: Journal    
DOI: 10.1177/0091270011419852     Document Type: Article

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