Imaging copper metabolism imbalance in Atp7b-/-knockout mouse model of Wilson's disease with PET-CT and orally administered 64CuCl2

Molecular Imaging and Biology

Volumn 14, Issue 5, 2012, Pages 600-607

  Peng, Fangyu ^a,b,c   Lutsenko, Svetlana ^d   Sun, Xiankai ^a,b   Muzik, Otto ^e  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS AT DALLAS   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

^e WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Copper (II) 64 chloride; Copper metabolism; PET CT; Positron emission tomography; Radiation dosimetry; Wilson's disease

Indexed keywords

COPPER; COPPER CHLORIDE CU 64; WILSON DISEASE PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; COMPUTER ASSISTED EMISSION TOMOGRAPHY; CONTROLLED STUDY; COPPER METABOLISM; DIAGNOSTIC IMAGING; DOSIMETRY; DRUG CLEARANCE; DRUG DISTRIBUTION; GASTROINTESTINAL ABSORPTION; ISOTOPE TRACING; KNOCKOUT MOUSE; MEAN RESIDENCE TIME; METAL METABOLISM; MOLECULAR IMAGING; MOUSE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIATION DOSE DISTRIBUTION; RADIATION EXPOSURE; RADIOACTIVITY; TISSUE DISTRIBUTION; WILSON DISEASE;

ADENOSINE TRIPHOSPHATASES; ADMINISTRATION, ORAL; ADULT; ANIMALS; CATION TRANSPORT PROTEINS; COPPER; COPPER RADIOISOTOPES; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HEPATOLENTICULAR DEGENERATION; HUMANS; MALE; MICE; MICE, KNOCKOUT; MOLECULAR IMAGING; POSITRON-EMISSION TOMOGRAPHY AND COMPUTED TOMOGRAPHY; RADIOMETRY; TIME FACTORS; TISSUE DISTRIBUTION;

ANIMALIA; MUS;

EID: 84870437158     PISSN: 15361632     EISSN: 18602002     Source Type: Journal    
DOI: 10.1007/s11307-011-0532-0     Document Type: Article

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