Whole animal copper flux assessed by positron emission tomography in the Long-Evans cinnamon rat - A feasibility study

BioMetals

Volumn 18, Issue 1, 2005, Pages 83-88

  Bissig, Karl Dimiter ^a   Honer, Michael ^b   Zimmermann, Kurt ^b   Summer, Karl H ^c   Solioz, Marc ^a  

^a UNIVERSITY OF BERN   (Switzerland)

^b PAUL SCHERRER INSTITUTE   (Switzerland)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Bile; Copper homeostasis; Long Evans cinnamon rats; Positron emission; Secretion; Tomography; Wilson disease

Indexed keywords

COPPER; COPPER EXPORTING ADENOSINE TRIPHOSPHATASE;

ABSORPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE; BILE FLOW; BILE SECRETION; CINNAMON; CONTROLLED STUDY; COPPER METABOLISM; EXPERIMENTAL MODEL; FEASIBILITY STUDY; FEMALE; GASTROINTESTINAL TRACT; INTERMETHOD COMPARISON; INTESTINE; LIVER; MOUSE STRAIN; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN EXPRESSION; RAT; REACTION TIME; STATISTICAL SIGNIFICANCE; STOMACH; TOXICITY; WHOLE BODY TOMOGRAPHY; WILD TYPE; WILSON DISEASE;

ADENOSINE TRIPHOSPHATASES; ANIMALS; CATION TRANSPORT PROTEINS; COPPER; ELECTROPHORESIS; FEMALE; INTESTINES; LIVER; ORGAN SIZE; OXYGEN; POSITRON-EMISSION TOMOGRAPHY; RATS; RATS, INBRED LEC; RATS, WISTAR; STOMACH; TIME FACTORS;

EID: 17744382587     PISSN: 09660844     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10534-004-1800-0     Document Type: Article

References (25)

1. NC Andrews 2002 Metal transporters and disease Curr. Opin. Chem. Biol. 6 181 186
2. GJ Brewer 1995 Practical recommendations and new therapies for Wilson's disease Drugs 50 240 249
3. GJ Brewer RD Dick VD Johnson JA Brunberg KJ Kluin JK Fink 1998 Treatment of Wilson's disease with zinc: XV long-term follow-up studies J. Lab Clin. Med. 132 264 278
4. F Bronner JH Yost 1985 Saturable and nonsaturable copper and calcium transport in mouse duodenum Am. J. Physiol. 249 G108 G112
5. P Ferenci K Caca G Loudianos G Mieli-Vergani S Tanner I Sternlieb M Schilsky D Cox F Berr 2003 Diagnosis and phenotypic classification of Wilson disease Liver 23 139 142
6. JR Forbes DW Cox 1998 Functional characterization of missense mutations in ATP7B: Wilson disease mutation or normal variant? Am. J. Hum. Genet. 63 1663 1674
7. M Harada S Sakisaka M Yoshitake S Shakadoh K Gondoh M Sata K Tanikawa 1993 Biliary copper excretion in acutely and chronically copper-loaded rats Hepatology 17 111 117
8. E Luk LT Jensen VC Culotta 2003 The many highways for intracellular trafficking of metals J. Biol. Inorg. Chem. 8 803 809
9. S Lutsenko JH Kaplan 1995 Organization of P-type ATPases: Significance of structural diversity Biochemistry 34 15607 15613
10. S Lutsenko R Tsivkovskii JM Walker 2003 Functional properties of the human copper-transporting ATPase ATP7B (the Wilson's disease protein) and regulation by metallochaperone Atox1 Ann. N. Y. Acad. Sci. 986 204 211
11. N Marceau N Aspin A Sass-Kortsak 1970 Absorption of copper 64 from gastrointestinal tract of the rat Am. J. Physiol. 218 377 383
12. JF Mercer N Barnes J Stevenson D Strausak RM Llanos 2003 Copper-induced trafficking of the Cu-ATPases: a key mechanism for copper homeostasis Biometals 16 175 184
13. H Muratsubaki K Satake Y Yamamoto K Enomoto 2002 Detection of serum proteins by native polyacrylamide gel electrophoresis using Blue Sepharose CL-6B-containing stacking gels Anal. Biochem. 307 337 340
14. K Petrukhin SG Fischer M Pirastu RE Tanzi I Chernov M Devoto LM Brzustowicz E Cayanis E Vitale JJ Russo 1993 Mapping, cloning and genetic characterization of the region containing the Wilson disease gene Nat Genet. 5 338 343
15. JR Prohaska AA Gybina 2004 Intracellular copper transport in mammals J. Nutr. 134 1003 1006
16. AJ Reader K Erlandsson MA Flower RJ Ott 1998 Fast accurate iterative reconstruction for low-statistics positron volume imaging Phys. Med. Biol. 43 835 846
17. H Schagger G von Jagow 1991 Blue native electrophoresis for isolation of membrane protein complexes in enzymatically active form Anal. Biochem. 199 223 231
18. 67Cu from irradiated zinc for use in antibody labelling: a comparison of methods Appl. Radiat. Isot. 46 329 336
19. AB Shah I Chernov HT Zhang BM Ross K Das S Lutsenko E Parano L Pavone O Evgrafov IA Ivanova-Smolenskaya G Anneren K Westermark FH Urrutia GK Penchaszadeh I Sternlieb IH Scheinberg TC Gilliam K Petrukhin 1997 Identification and analysis of mutations in the Wilson disease gene (ATP7B): population frequencies, genotype-phenotype correlation, and functional analyses Am. J. Hum. Genet. 61 317 328
20. M Solioz C Vulpe 1996 CPx-type ATPases: a class of P-type ATPases that pump heavy metals Trends Biochem. Sci. 21 237 241
21. RE Tanzi K Petrukhin I Chernov JL Pellequer W Wasco B Ross DM Romano E Parano L Pavone LM Brzustowicz 1993 The Wilson disease gene is a copper transporting ATPase with homology to the Menkes disease gene Nature Genet. 5 344 350
22. K Terada T Sugiyama 1999 The Long-Evans Cinnamon rat: an animal model for Wilson's disease Pediatr. Int. 41 414 418
23. DJ Thiele 2003 Integrating trace element metabolism from the cell to the whole organism J. Nutr. 133 1579S 1580S
24. van CampenDR, MitchellAE. 1965 Absorption of Cu-64, Zn-65, Mo-99, and Fe-59 from ligated segments of the rat gastrintestinal tract. J. Nutr. 120-124.
25. J Wu JR Forbes HS Chen DW Cox 1994 The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene Nature Genet. 7 541 545