Water quality in conventional and home haemodialysis

Nature Reviews Nephrology

Volumn 8, Issue 12, 2012, Pages 725-734

  Damasiewicz, Matthew J ^a   Polkinghorne, Kevan R ^a   Kerr, Peter G ^a  

^a MONASH MEDICAL CENTRE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ALUMINUM; CALCIUM; CHLORINE; COPPER; DIALYSIS FLUID; FLUORIDE; HYPOCHLORITE; LEAD; MAGNESIUM; NITRATE; TOSYLCHLORAMIDE SODIUM; ZINC;

ABDOMINAL PAIN; ACHROMOBACTER; ACINETOBACTER; AEROMONAS; ALCALIGENES; BACTERIUM CONTAMINATION; BIOCOMPATIBILITY; BIOFILM; BRAIN DISEASE; BURKHOLDERIA CEPACIA; CONVENTIONAL HEMODIALYSIS; DIALYSATE; DIALYSIS MEMBRANE; ENTEROBACTER CLOACAE; ENVIRONMENTAL ASPECTS AND RELATED PHENOMENA; FEVER; FINANCE; FLAVOBACTERIUM; HEADACHE; HEMODIALYSIS MACHINE; HEMOLYTIC ANEMIA; HOME DIALYSIS; HUMAN; METHEMOGLOBINEMIA; MUSCLE WEAKNESS; MYCOBACTERIUM; NAUSEA AND VOMITING; NONHUMAN; OCHROBACTRUM; PRIORITY JOURNAL; PSEUDOMONADACEAE; RENAL REPLACEMENT THERAPY; REVERSE OSMOSIS; REVIEW; SERRATIA; SPHINGOMONAS; ULTRAFILTRATION; VIBRIO; WATER CONTAMINATION; WATER MANAGEMENT; WATER QUALITY; WATER SUPPLY;

AMBULATORY CARE FACILITIES; HEMODIALYSIS, HOME; HUMANS; KIDNEY FAILURE, CHRONIC; WATER PURIFICATION; WATER SUPPLY;

EID: 84870436632     PISSN: 17595061     EISSN: 1759507X     Source Type: Journal    
DOI: 10.1038/nrneph.2012.241     Document Type: Review

References (115)

1. Marshall, M. R. et al. Home hemodialysis and mortality risk in Australian and New Zealand populations. Am. J. Kidney Dis. 58, 782-793 (2011).
2. Saran, R. et al. Longer treatment time and slower ultrafiltration in hemodialysis: associations with reduced mortality in the DOPPS. Kidney Int. 69, 1222-1228 (2006).
3. Culleton, B. F. et al. Effect of frequent nocturnal hemodialysis vs conventional hemodialysis on left ventricular mass and quality of life: a randomized controlled trial. JAMA 298, 1291-1299 (2007).
4. Kerr, P. G., Agar, J. W. & Hawley, C. M. Alternate night nocturnal hemodialysis: the Australian experience. Semin. Dial. 24, 664-667 (2011).
5. Masterson, R. The advantages and disadvantages of home hemodialysis. Hemodial. Int. 12 (Suppl. 1), S16-S20 (2008).
6. ANSI/AAMI/ISO. ISO 26722:2009. Water treatment equipment for hemodialysis applications and related therapies [online], http://www.iso.org/iso/home/store/ catalogue-tc/catalogue-detail.htm?csnumber=43700 (2009).
7. Tsuchida, K., Nakamura, M., Yoshikawa, K., Minakuchi, J. & Takesawa, S. Current situation of endotoxin retentive filter. Blood Purif. 27 (Suppl. 1), 28-35 (2009).
8. Junglee, N. A. et al. When pure is not so pure: chloramine-related hemolytic anemia in home hemodialysis patients. Hemodial. Int. 14, 327-332 (2010).
9. Freeman, R. M., Lawton, R. L. & Chamberlain, M. A. Hard-water syndrome. N. Engl. J. Med. 276, 1113-1118 (1967).
10. Dunea, G., Mahurkar, S. D., Mamdani, B. & Smith, E. C. Role of aluminum in dialysis dementia. Ann. Intern. Med. 88, 502-504 (1978).
11. Alfrey, A. C., LeGendre, G. R. & Kaehny, W. D. The dialysis encephalopathy syndrome. Possible aluminum intoxication. N. Engl. J. Med. 294, 184-188 (1976).
12. Parkinson, I. S., Ward, M. K. & Kerr, D. N. Dialysis encephalopathy, bone disease and anaemia: the aluminum intoxication syndrome during regular haemodialysis. J. Clin. Pathol. 34, 1285-1294 (1981).
13. Hoenich, N. A. & Levin, R. The implications of water quality in hemodialysis. Semin. Dial. 16, 492-497 (2003).
14. Johnson, W. J. & Taves, D. R. Exposure to excessive fluoride during hemodialysis. Kidney Int. 5, 451-454 (1974).
15. Lough, J., Noonan, R., Gagnon, R. & Kaye, M. Effects of fluoride on bone in chronic renal failure. Arch. Pathol. 99, 484-487 (1975).
16. Rao, T. K. & Friedman, E. A. Editorial: fluoride and bone disease in uremia. Kidney Int. 7, 125-129 (1975).
17. Eaton, J. W., Kolpin, C. F., Swofford, H. S., Kjellstrand, C. M. & Jacob, H. S. Chlorinated urban water: a cause of dialysis-induced hemolytic anemia. Science 181, 463-464 (1973).
18. Ward, D. M. Chloramine removal from water used in hemodialysis. Adv. Ren. Replace. Ther. 3, 337-347 (1996).
19. Neilan, B. A., Ehlers, S. M., Kolpin, C. F. & Eaton, J. W. Prevention of chloramine-induced hemolysis in dialyzed patients. Clin. Nephrol. 10, 105-108 (1978).
20. Kathuria, P., Nair, B., Schram, D. & Medlock, R. Outbreak of lead poisoning in a hemodialysis unit. J. Am. Soc. Nephrol. 15, 617A (2004).
21. Lin, J. L. et al. Blood lead levels, malnutrition, inflammation, and mortality in patients with diabetes treated by long-term hemodialysis. Am. J. Kidney Dis. 51, 107-115 (2008).
22. Davenport, A., Murcutt, G. & Whiting, S. Cross-sectional audit of blood lead levels in regular outpatient haemodialysis patients dialysing in north London. Nephrology (Carlton) 14, 476-481 (2009).
23. Tonelli, M. et al. Trace elements in hemodialysis patients: a systematic review and meta-analysis. BMC Med. 7, 25 (2009).
24. ANSI/AAMI/ISO. ISO 13959:2009. Water for haemodialysis and related therapies [online], http://www.iso.org/iso/home/store/catalogue-tc/catalogue- detail.htm?csnumber=43699 (2009).
25. Poli, D. et al. Organic contamination in dialysis water: trichloroethylene as a model compound. Nephrol. Dial. Transplant. 21, 1618-1625 (2006).
26. Borges, C. R., Lascowski, K. M., Filho, N. R. & Pelayo, J. S. Microbiological quality of water and dialysate in a haemodialysis unit in Ponta Grossa-PR, Brazil. J. Appl. Microbiol. 103, 1791-1797 (2007).
27. Klein, E., Pass, T., Harding, G. B., Wright, R. & Million, C. Microbial and endotoxin contamination in water and dialysate in the central United States. Artif. Organs 14, 85-94 (1990).
28. Doern, G. V., Brogden, B. E., DiFederico, J. D., Earls, J. E. & Quinn, M. L. Quantitative microbiological monitoring of hemodialysis fluids: evaluation of methods and demonstration of lack of test relevance in single-pass hemodialysis machines with automatic dialysate proportioning with reverse osmosis-treated tap water. J. Clin. Microbiol. 16, 1025-1029 (1982).
29. Bland, L. A., Ridgeway, M. R., Aguero, S. M., Carson, L. A. & Favero, M. S. Potential bacteriologic and endotoxin hazards associated with liquid bicarbonate concentrate. ASAIO Trans. 33, 542-545 (1987).
30. Lonnemann, G. The quality of dialysate: an integrated approach. Kidney Int. Suppl. 76, S112-S119 (2000).
31. Ebben, J. P., Hirsch, D. N., Luehmann, D. A., Collins, A. J. & Keshaviah, P. R. Microbiologic contamination of liquid bicarbonate concentrate for hemodialysis. ASAIO Trans. 33, 269-273 (1987).
32. Flemming, H. C. & Wingender, J. The biofilm matrix. Nat. Rev. Microbiol. 8, 623-633 (2010).
33. Costerton, J. W., Stewart, P. S. & Greenberg, E. P. Bacterial biofilms: a common cause of persistent infections. Science 284, 1318-1322 (1999).
34. Schindler, R. et al. Short bacterial DNA fragments: detection in dialysate and induction of cytokines. J. Am. Soc. Nephrol. 15, 3207-3214 (2004).
35. Navarro, M. D. et al. Bacterial DNA prolongs the survival of inflamed mononuclear cells in haemodialysis patients. Nephrol. Dial. Transplant. 22, 3580-3585 (2007).
36. Nystrand, R. Microbiology of water and fluids for hemodialysis. J. Chin. Med. Assoc. 71, 223-229 (2008).
37. Hindman, S. H. et al. Pyrogenic reactions during haemodialysis caused by extramural endotoxin. Lancet 2, 732-734 (1975).
38. Bernick, J. J., Port, F. K., Favero, M. S. & Brown, D. G. Bacterial and endotoxin permeability of hemodialysis membranes. Kidney Int. 16, 491-496 (1979).
39. Gordon, S. M. et al. Pyrogenic reactions in patients receiving conventional, high-efficiency, or high-flux hemodialysis treatments with bicarbonate dialysate containing high concentrations of bacteria and endotoxin. J. Am. Soc. Nephrol. 2, 1436-1444 (1992).
40. ANSI/AAMI/ISO. ISO 11663:2009. Quality of dialysis fluid for haemodialysis and related therapies [online], http://www.iso.org/iso/home/store/ catalogue-tc/catalogue-detail.htm?csnumber=50660 (2009).
41. ANSI/AAMI/ISO. ISO 13958:2009. Concentrates for hemodialysis and related therapies [online], http://www.iso.org/iso/home/store/catalogue-tc/catalogue- detail.htm?csnumber=43698 (2009).
42. ANSI/AAMI/ISO. ISO 23500:2011. Guidance for the preparation and quality management of fluids for hemodialysis and related therapies [online], http://www.iso.org/iso/home/store/catalogue-tc/catalogue-detail.htm?csnumber= 45345 (2011).
43. World Health Organization. Guidelines for drinking-water quality (World Health Organization, Geneva, 2011).
44. Gomila, M. et al. A molecular microbial ecology approach to studying hemodialysis water and fluid. Kidney Int. 70, 1567-1576 (2006).
45. Harding, G. B. et al. Bacterial contamination of hemodialysis center water and dialysate: are current assays adequate? Artif. Organs 13, 155-159 (1989).
46. Lonnemann, G. Assessment of the quality of dialysate. Nephrol. Dial. Transplant. 13 (Suppl. 5), 17-20 (1998).
47. Reasoner, D. J. & Geldreich, E. E. A new medium for the enumeration and subculture of bacteria from potable water. Appl. Environ. Microbiol. 49, 1-7 (1985).
48. Pass, T., Wright, R., Sharp, B. & Harding, G. B. Culture of dialysis fluids on nutrient-rich media for short periods at elevated temperatures underestimate microbial contamination. Blood Purif. 14, 136-145 (1996).
49. van der Linde, K., Lim, B. T., Rondeel, J. M., Antonissen, L. P. & de Jong, G. M. Improved bacteriological surveillance of haemodialysis fluids: a comparison between Tryptic soy agar and Reasoner's 2A media. Nephrol. Dial. Transplant. 14, 2433-2437 (1999).
50. Harding, G. B., Pass, T. & Wright, R. Bacteriology of hemodialysis fluids: are current methodologies meaningful? Artif. Organs 16, 448-456 (1992).
51. Riepl, M. et al. Applicability of solid-phase cytometry and epifluorescence microscopy for rapid assessment of the microbiological quality of dialysis water. Nephrol. Dial. Transplant. 26, 3640-3645 (2011).
52. Kharazmi, A., Giwercman, B. & Hoiby, N. Robbins device in biofilm research. Methods Enzymol. 310, 207-215 (1999).
53. Hurley, J. C. Endotoxemia: methods of detection and clinical correlates. Clin. Microbiol. Rev. 8, 268-292 (1995).
54. Tsuchida, K. et al. Detection of peptidoglycan and endotoxin in dialysate, using silkworm larvae plasma and limulus amebocyte lysate methods. Nephron 75, 438-443 (1997).
55. Glorieux, G. et al. A novel bio-assay increases the detection yield of microbiological impurity of dialysis fluid, in comparison to the LAL-test. Nephrol. Dial. Transplant. 24, 548-554 (2009).
56. Cappelli, G. et al. Water treatment and monitor disinfection. Hemodial. Int. 10 (Suppl. 1), S13-S18 (2006).
57. Vincent, F. C., Tibi, A. R. & Darbord, J. C. A bacterial biofilm in a hemodialysis system. Assessment of disinfection and crossing of endotoxin. ASAIO Trans. 35, 310-313 (1989).
58. Morin, P. Identification of the bacteriological contamination of a water treatment line used for haemodialysis and its disinfection. J. Hosp. Infect. 45, 218-224 (2000).
59. Stragier, A. & Jadoul, M. Ultraviolet irradiation to preserve high reverse osmosis water quality. Clin. Nephrol. 63, 35-40 (2005).
60. Tarrass, F., Benjelloun, M. & Benjelloun, O. Current understanding of ozone use for disinfecting hemodialysis water treatment systems. Blood Purif. 30, 64-70 (2010).
61. Pontoriero, G., Pozzoni, P., Andrulli, S. & Locatelli, F. The quality of dialysis water. Nephrol. Dial. Transplant. 18 (Suppl. 7), vii21-vii25; discussion vii56 (2003).
62. Chang, C. Y., Hsieh, Y. H., Hsu, S. S., Hu, P. Y. & Wang, K. H. The formation of disinfection by-products in water treated with chlorine dioxide. J. Hazard Mater. 79, 89-102 (2000).
63. Sakuma, K. et al. Experience of using heat citric acid disinfection method in central dialysis fluid delivery system. J. Artif. Organs 13, 145-150 (2010).
64. Libman, V. Use of Reynolds number as a criterion for design of high-purity water systems. Ultrapure Water 23, 26-34 (2006).
65. Cheung, A. K. & Leypoldt, J. K. The hemodialysis membranes: a historical perspective, current state and future prospect. Semin. Nephrol. 17, 196-213 (1997).
66. Kerr, P. G. & Huang, L. Review: membranes for haemodialysis. Nephrology (Carlton) 15, 381-385 (2010).
67. Hakim, R. M., Wingard, R. L., Husni, L., Parker, R. A. & Parker, T. F. 3rd. The effect of membrane biocompatibility on plasma beta 2-microglobulin levels in chronic hemodialysis patients. J. Am. Soc. Nephrol. 7, 472-478 (1996).
68. Hakim, R. M. et al. Effect of the dialysis membrane on mortality of chronic hemodialysis patients. Kidney Int. 50, 566-570 (1996).
69. Hakim, R. M. Influence of the dialysis membrane on outcome of ESRD patients. Am. J. Kidney Dis. 32, S71-S75 (1998).
70. van Ypersele de Strihou, C., Jadoul, M., Malghem, J., Maldague, B. & Jamart, J. Effect of dialysis membrane and patient's age on signs of dialysis-related amyloidosis. The Working Party on Dialysis Amyloidosis. Kidney Int. 39, 1012-1019 (1991).
71. Woods, H. F. & Nandakumar, M. Improved outcome for haemodialysis patients treated with high-flux membranes. Nephrol. Dial. Transplant. 15 (Suppl. 1), 36-42 (2000).
72. Port, F. K. et al. Mortality risk by hemodialyzer reuse practice and dialyzer membrane characteristics: results from the USRDS dialysis morbidity and mortality study. Am. J. Kidney Dis. 37, 276-286 (2001).
73. Bloembergen, W. E. et al. Relationship of dialysis membrane and cause-specific mortality. Am. J. Kidney Dis. 33, 1-10 (1999).
74. Cheung, A. K. et al. Effects of high-flux hemodialysis on clinical outcomes: results of the HEMO study. J. Am. Soc. Nephrol. 14, 3251-3263 (2003).
75. Locatelli, F. et al. Effect of membrane permeability on survival of hemodialysis patients. J. Am. Soc. Nephrol. 20, 645-654 (2009).
76. Schiffl, H. High-flux dialyzers, backfiltration, and dialysis fluid quality. Semin. Dial. 24, 1-4 (2011).
77. Pertosa, G., Grandaliano, G., Gesualdo, L. & Schena, F. P. Clinical relevance of cytokine production in hemodialysis. Kidney. Int. Suppl. 76, S104-S111 (2000).
78. Pertosa, G., Gesualdo, L., Bottalico, D. & Schena, F. P. Endotoxins modulate chronically tumour necrosis factor alpha and interleukin 6 release by uraemic monocytes. Nephrol. Dial. Transplant. 10, 328-333 (1995).
79. Dinarello, C. A. Interleukin-1 and interleukin-1 receptor antagonist production during haemodialysis: which cytokine is a surrogate marker for dialysis-related complications? Nephrol. Dial. Transplant. 10 (Suppl. 3), 25-28 (1995).
80. Memoli, B. et al. Hemodialysis related induction of interleukin-6 production by peripheral blood mononuclear cells. Kidney Int. 42, 320-326 (1992).
81. Arici, M. & Walls, J. End-stage renal disease, atherosclerosis, and cardiovascular mortality: is C-reactive protein the missing link? Kidney Int. 59, 407-414 (2001).
82. Zimmermann, J., Herrlinger, S., Pruy, A., Metzger, T. & Wanner, C. Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int. 55, 648-658 (1999).
83. Stenvinkel, P. et al. Strong association between malnutrition, inflammation, and atherosclerosis in chronic renal failure. Kidney Int. 55, 1899-1911 (1999).
84. Sitter, T., Bergner, A. & Schiffl, H. Dialysate related cytokine induction and response to recombinant human erythropoietin in haemodialysis patients. Nephrol. Dial. Transplant. 15, 1207-1211 (2000).
85. Canaud, B. & Granger-Vallee, A. Should ultrapure dialysate be part of standard therapy in hemodialysis? Semin. Dial. 24, 426-427 (2011).
86. Rahmati, M. A. et al. The role of improved water quality on inflammatory markers in patients undergoing regular dialysis. Int. J. Artif. Organs 27, 723-727 (2004).
87. Arizono, K. et al. Use of ultrapure dialysate in reduction of chronic inflammation during hemodialysis. Blood Purif. 22 (Suppl. 2), 26-29 (2004).
88. Hsu, P. Y. et al. Ultrapure dialysate improves iron utilization and erythropoietin response in chronic hemodialysis patients-a prospective cross-over study. J. Nephrol. 17, 693-700 (2004).
89. Schiffl, H., Lang, S. M. & Fischer, R. Ultrapure dialysis fluid slows loss of residual renal function in new dialysis patients. Nephrol. Dial. Transplant. 17, 1814-1818 (2002).
90. Lederer, S. R. & Schiffl, H. Ultrapure dialysis fluid lowers the cardiovascular morbidity in patients on maintenance hemodialysis by reducing continuous microinflammation. Nephron 91, 452-455 (2002).
91. Lonnemann, G. & Koch, K. M. β2-microglobulin amyloidosis: effects of ultrapure dialysate and type of dialyzer membrane. J. Am. Soc. Nephrol. 13 (Suppl. 1), S72-S77 (2002).
92. Izuhara, Y. et al. Ultrapure dialysate decreases plasma pentosidine, a marker of "carbonyl stress". Am. J. Kidney Dis. 43, 1024-1029 (2004).
93. Canaud, B. et al. Mortality risk for patients receiving hemodiafiltration versus hemodialysis: European results from the DOPPS. Kidney Int. 69, 2087-2093 (2006).
94. Panichi, V. et al. Chronic inflammation and mortality in haemodialysis: effect of different renal replacement therapies. Results from the RISCAVID study. Nephrol. Dial. Transplant. 23, 2337-2343 (2008).
95. Jirka, T. et al. Mortality risk for patients receiving hemodiafiltration versus hemodialysis. Kidney Int. 70, 1524; author reply 1524-1525 (2006).
96. Penne, E. L. et al. Microbiological quality and quality control of purified water and ultrapure dialysis fluids for online hemodiafiltration in routine clinical practice. Kidney Int. 76, 665-672 (2009).
97. Ayus, J. C. et al. Effects of short daily versus conventional hemodialysis on left ventricular hypertrophy and inflammatory markers: a prospective, controlled study. J. Am. Soc. Nephrol. 16, 2778-2788 (2005).
98. Yuen, D., Richardson, R. M., Fenton, S. S., McGrath-Chong, M. E. & Chan, C. T. Quotidian nocturnal hemodialysis improves cytokine profile and enhances erythropoietin responsiveness. ASAIO J. 51, 236-241 (2005).
99. Susantitaphong, P., Koulouridis, I., Balk, E. M., Madias, N. E. & Jaber, B. L. Effect of frequent or extended hemodialysis on cardiovascular parameters: a meta-analysis. Am. J. Kidney Dis. 59, 689-699 (2012).
100. Weinhandl, E. D., Liu, J., Gilbertson, D. T., Arneson, T. J. & Collins, A. J. Survival in daily home hemodialysis and matched thrice-weekly in-center hemodialysis patients. J. Am. Soc. Nephrol. 23, 895-904 (2012).
101. Chertow, G. M. et al. In-center hemodialysis six times per week versus three times per week. N. Engl. J. Med. 363, 2287-2300 (2010).
102. Pierratos, A. et al. Nocturnal hemodialysis: three-year experience. J. Am. Soc. Nephrol. 9, 859-868 (1998).
103. Agar, J. W. Conserving water in and applying solar power to haemodialysis: 'green dialysis' through wiser resource utilization. Nephrology (Carlton) 15, 448-453 (2010).
104. Agar, J. W., Simmonds, R. E., Knight, R. & Somerville, C. A. Using water wisely: new, affordable, and essential water conservation practices for facility and home hemodialysis. Hemodial. Int. 13, 32-37 (2009).
105. Agar, J. W., Perkins, A. & Tjipto, A. Solar-assisted hemodialysis. Clin. J. Am. Soc. Nephrol. 7, 310-314 (2012).
106. Agar, J. W. Review: understanding sorbent dialysis systems. Nephrology (Carlton) 15, 406-411 (2010).
107. Gordon, A. et al. Clinical maintenance hemodialysis with a sorbent-based, low-volume dialysate regeneration system. Trans. Am. Soc. Artif. Intern. Organs 17, 253-258 (1971).
108. Ash, S. R. The Allient dialysis system. Semin. Dial. 17, 164-166 (2004).
109. Shapiro, W. B. The current status of sorbent hemodialysis. Semin. Dial. 3, 40-45 (1990).
110. Clark, W. R. & Turk, J. E. Jr. The NxStage System One. Semin. Dial. 17, 167-170 (2004).
111. Tipple, M. A. et al. Illness in hemodialysis patients after exposure to chloramine contaminated dialysate. ASAIO Trans. 37, 588-591 (1991).
112. Arnow, P. M., Bland, L. A., Garcia-Houchins, S., Fridkin, S. & Fellner, S. K. An outbreak of fatal fluoride intoxication in a long-term hemodialysis unit. Ann. Intern. Med. 121, 339-344 (1994).
113. Carlson, D. J. & Shapiro, F. L. Methemoglobinemia from well water nitrates: a complication of home dialysis. Ann. Intern. Med. 73, 757-759 (1970).
114. Manzler, A. D. & Schreiner, A. W. Copper-induced acute hemolytic anemia. A new complication of hemodialysis. Ann. Intern. Med. 73, 409-412 (1970).
115. Gallery, E. D., Blomfield, J. & Dixon, S. R. Acute zinc toxicity in haemodialysis. Br. Med. J. 4, 331-333 (1972).