High-Flux Dialyzers, Backfiltration, and Dialysis Fluid Quality

Seminars in Dialysis

Volumn 24, Issue 1, 2011, Pages 1-4

  Schiffl, Helmut ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

HEMODIALYSIS FLUID;

ARTIFICIAL MEMBRANE; CHRONIC KIDNEY FAILURE; EDITORIAL; HUMAN; METHODOLOGY; RENAL REPLACEMENT THERAPY; STANDARD;

HEMODIALYSIS SOLUTIONS; HUMANS; KIDNEY FAILURE, CHRONIC; MEMBRANES, ARTIFICIAL; RENAL DIALYSIS;

EID: 79951791222     PISSN: 08940959     EISSN: 1525139X     Source Type: Journal    
DOI: 10.1111/j.1525-139X.2010.00786.x     Document Type: Editorial

References (39)

1. Eknoyan G, Beck GJ, Cheung AK, Daugirdas JT, Greene T, Kusek JW, Allon M, Bailey J, Delmez JA, Depner TA, Dwyer JT, Levey AS, Levin NW, Milford E, Ornt DB, Rocco MV, Schulman G, Schwab SJ, Teehan BP, Toto R: Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med 347:2010-2019, 2002
2. Blankestijn PJ, Ledebo I, Canaud B: Hemodiafiltration: clinical evidence and remaining questions. Kidney Int 77:581-587, 2010
3. Vanholder R, De Smet R, Glorieux G, Argiles A, Baurmeister U, Brunet P, Clark W, Cohen G, De Deyn PP, Deppisch R, Descamps-Latscha B, Henle T, Jorres A, Lemke HD, Massy ZA, Passlick-Deetjen J, Rodriguez M, Stegmayr B, Stenvinkel P, Tetta C, Wanner C, Zidek W: Review on uremic toxins: classification, concentration, and interindividual variability. Kidney Int 63:1934-1943, 2003
4. Woods HF, Nandakumar M: Improved outcome for haemodialysis patients treated with high-flux membranes. Nephrol Dial Transplant 15(Suppl. 1):36-42, 2000
5. Port FK, Wolfe RA, Hulbert-Shearon TE, Daugirdas JT, Agodoa LY, Jones C, Orzol SM, Held PJ: Mortality risk by hemodialyzer reuse practice and dialyzer membrane characteristics: results from the USRDS dialysis morbidity and mortality study. Am J Kidney Dis 37:276-286, 2001
6. Krane V, Krieter DH, Olschewski M, Marz W, Mann JF, Ritz E, Wanner C: Dialyzer membrane characteristics and outcome of patients with type 2 diabetes on maintenance hemodialysis. Am J Kidney Dis 49:267-275, 2007
7. Chauveau P, Nguyen H, Combe C, Chene G, Azar R, Cano N, Canaud B, Fouque D, Laville M, Leverve X, Roth H, Aparicio M: Dialyzer membrane permeability and survival in hemodialysis patients. Am J Kidney Dis 45:565-571, 2005
8. Yokoyama H, Kawaguchi T, Wada T, Takahashi Y, Higashi T, Yamazaki S, Fukuhara S, Akiba T, Akizawa T, Asano Y, Kurokawa K, Saito A: Biocompatibility and permeability of dialyzer membranes do not affect anemia, erythropoietin dosage or mortality in japanese patients on chronic non-reuse hemodialysis: a prospective cohort study from the J-DOPPS II study. Nephron Clin Pract 109:c100-c108, 2008
9. Locatelli F, Martin-Malo A, Hannedouche T, Loureiro A, Papadimitriou M, Wizemann V, Jacobson SH, Czekalski S, Ronco C, Vanholder R: Effect of membrane permeability on survival of hemodialysis patients. J Am Soc Nephrol 20:645-654, 2009
10. Cheung AK, Levin NW, Greene T, Agodoa L, Bailey J, Beck G, Clark W, Levey AS, Leypoldt JK, Ornt DB, Rocco MV, Schulman G, Schwab S, Teehan B, Eknoyan G: Effects of high-flux hemodialysis on clinical outcomes: results of the HEMO study. J Am Soc Nephrol 14:3251-3263, 2003
11. Delmez JA, Yan G, Bailey J, Beck GJ, Beddhu S, Cheung AK, Kaysen GA, Levey AS, Sarnak MJ, Schwab SJ: Cerebrovascular disease in maintenance hemodialysis patients: results of the HEMO Study. Am J Kidney Dis 47:131-138, 2006
12. Kerr PG, Huang L: Review: membranes for haemodialysis. Nephrology (Carlton) 15:381-385, 2010
13. Ward RA: Ultrapure dialysate. Semin Dial 17:489-497, 2004
14. Klinkmann H, Ebbighausen H, Uhlenbusch I, Vienken J: High-flux dialysis, dialysate quality and backtransport. Contrib Nephrol 103:89-97, 1993
15. Stiller S, Mann H, Brunner H: Backfiltration in hemodialysis with highly permeable membranes. Contrib Nephrol 46:23-32, 1985
16. Leypoldt JK, Schmidt B, Gurland HJ: Measurement of backfiltration rates during hemodialysis with highly permeable membranes. Blood Purif 9:74-84, 1991
17. Leypoldt JK, Schmidt B, Gurland HJ: Net ultrafiltration may not eliminate backfiltration during hemodialysis with highly permeable membranes. Artif Organs 15:164-170, 1991
18. Ronco C, Orlandini G, Brendolan A, Lupi A, La Greca G: Enhancement of convective transport by internal filtration in a modified experimental hemodialyzer: technical note. Kidney Int 54:979-985, 1998
19. Bommer J: Sterile filtration of dialysate: is it really of no use? Nephrol Dial Transplant 16:1992-1994, 2001
20. Mege JL, Sanguedolce MV, Purgus R, Moulin B, Bongrand P, Capo C, Olmer M: Chronic and intradialytic effects of high-flux hemodialysis on tumor necrosis factor-alpha production: relationship to endotoxins. Am J Kidney Dis 20:482-488, 1992
21. Yamagami S, Adachi T, Sugimura T, Wada S, Kishimoto T, Maekawa M, Yoshimura R, Niwa M, Terano Y, Shaldon S: Detection of endotoxin antibody in long-term dialysis patients. Int J Artif Organs 13:205-210, 1990
22. Vanholder R, Van Haecke E, Veys N, Ringoir S: Endotoxin transfer through dialysis membranes: small- versus large-pore membranes. Nephrol Dial Transplant 7:333-339, 1992
23. Panichi V, Tetta C, Rindi P, Palla R, Lonnemann G: Plasma C-reactive protein is linked to backfiltration associated interleukin-6 production. ASAIO J 44:M415-M417, 1998
24. Lonnemann G, Behme TC, Lenzner B, Floege J, Schulze M, Colton CK, Koch KM, Shaldon S: Permeability of dialyzer membranes to TNF alpha-inducing substances derived from water bacteria. Kidney Int 42:61-68, 1992
25. Hosoya N, Sakai K: Backdiffusion rather than backfiltration enhances endotoxin transport through highly permeable dialysis membranes. ASAIO Trans 36:M311-M313, 1990
26. Schiffl H, Lang SM, Fischer R: Ultrapure dialysis fluid slows loss of residual renal function in new dialysis patients. Nephrol Dial Transplant 17:1814-1818, 2002
27. Sitter T, Bergner A, Schiffl H: Dialysate related cytokine induction and response to recombinant human erythropoietin in haemodialysis patients. Nephrol Dial Transplant 15:1207-1211, 2000
28. Molina M, Navarro MJ, Palacios ME, de Gracia MC, Garcia Hernandez MA, Rios MF, Perez Silva FM: [Importance of ultrapure dialysis liquid in response to the treatment of renal anaemia with darbepoetin in patients receiving haemodialysis]. Nefrologia 27:196-201, 2007
29. Schiffl H, Lang SM, Stratakis D, Fischer R: Effects of ultrapure dialysis fluid on nutritional status and inflammatory parameters. Nephrol Dial Transplant 16:1863-1869, 2001
30. Rahmati MA, Homel P, Hoenich NA, Levin R, Kaysen GA, Levin NW: The role of improved water quality on inflammatory markers in patients undergoing regular dialysis. Int J Artif Organs 27:723-727, 2004
31. Ouseph R, Jones S, Dhananjaya N, Ward RA: Use of ultrafiltered dialysate is associated with improvements in haemodialysis-associated morbidity in patients treated with reused dialysers. Nephrol Dial Transplant 22:2269-2275, 2007
32. Baz M, Durand C, Ragon A, Jaber K, Andrieu D, Merzouk T, Purgus R, Olmer M, Reynier JP, Berland Y: Using ultrapure water in hemodialysis delays carpal tunnel syndrome. Int J Artif Organs 14:681-685, 1991
33. Koda Y, Nishi S, Miyazaki S, Haginoshita S, Sakurabayashi T, Suzuki M, Sakai S, Yuasa Y, Hirasawa Y, Nishi T: Switch from conventional to high-flux membrane reduces the risk of carpal tunnel syndrome and mortality of hemodialysis patients. Kidney Int 52:1096-1101, 1997
34. Honda H, Suzuki H, Hosaka N, Hirai Y, Sanada D, Nakamura M, Nagai H, Ashikaga E, Matsumoto K, Mukai M, Watanabe M, Akizawa T: Ultrapure dialysate influences serum myeloperoxidase levels and lipid metabolism. Blood Purif 28:29-39, 2009
35. Schiffl H, Lang SM: Effects of dialysis purity on uremic dyslipidemia. Ther Apher Dial 14:5-11, 2010
36. Tao J, Sun Y, Li X, Li H, Liu S, Wen Y, Duan L, Li Y, Li X: Conventional versus ultrapure dialysate for lowering serum lipoprotein(a) levels in patients on long-term hemodialysis: a randomized trial. Int J Artif Organs 33:290-296, 2010
37. McKane W, Chandna SM, Tattersall JE, Greenwood RN, Farrington K: Identical decline of residual renal function in high-flux biocompatible hemodialysis and CAPD. Kidney Int 61:256-265, 2002
38. Blagg CR, Twardowski ZJ, Bower J, Kiellstrand CM: Cardiovascular instability and dialysate purity.(abstract). ASAIO J 49:190, 2003
39. Lederer SR, Schiffl H: Ultrapure dialysis fluid lowers the cardiovascular morbidity in patients on maintenance hemodialysis by reducing continuous microinflammation. Nephron 91:452-455, 2002