-
1
-
-
0030928619
-
Gene therapy-promises, problems and prospects
-
(a) Verma, I.M.; Somia, N. Gene therapy-promises, problems and prospects. Nature, 1997, 389, 239-242.
-
(1997)
Nature
, vol.389
, pp. 239-242
-
-
Verma, I.M.1
Somia, N.2
-
2
-
-
0030623524
-
Advances in understanding the pharmacological properties of antisense oligonucleotides
-
(b) Crooke, S.T. Advances in understanding the pharmacological properties of antisense oligonucleotides. Adv. Pharmacol., 1997, 40, 1-49.
-
(1997)
Adv. Pharmacol.
, vol.40
, pp. 1-49
-
-
Crooke, S.T.1
-
3
-
-
0031009465
-
Antisense aims for a renaissance
-
(c) Roush, W. Antisense aims for a renaissance. Science, 1997, 276, 1192-1193.
-
(1997)
Science
, vol.276
, pp. 1192-1193
-
-
Roush, W.1
-
4
-
-
11944267365
-
Antisense oliglonucleotides: A new therapeutic principles
-
(d) Uhlmann, E.; Peyman, A. Antisense oliglonucleotides: a new therapeutic principles. Chem. Rev. 1990, 90, 543-584.
-
(1990)
Chem. Rev.
, vol.90
, pp. 543-584
-
-
Uhlmann, E.1
Peyman, A.2
-
5
-
-
84870457892
-
-
Mountain, A.; Ney, U.; Schomburg, D., Eds.; Wiley-VCH
-
Carter, B.J. In: Viral vectors for gene therapy. Biotechnology; Mountain, A.; Ney, U.; Schomburg, D., Eds.; Wiley-VCH, 1998; Vol. 5a, pp. 397-421.
-
(1998)
Viral Vectors for Gene Therapy. Biotechnology
, vol.5 A
, pp. 397-421
-
-
Carter, B.J.1
-
6
-
-
0037448352
-
A serious adverse event after successful gene therapy for X-linked severe combine immunodeficiency
-
(a) Hacein-Bey-Abina, S.; von Kalle, C.; Shmidt, M.; Le Deist, F.; Wulffraat, N.; McIntyre, E.; Radford, I.; Villeval, J.L.; Fraser, C.C.; Cavazzana-Calvo, M. A serious adverse event after successful gene therapy for X-linked severe combine immunodeficiency. N. Engl. J. Med, 2003, 348(3), 255.
-
(2003)
N. Engl. J. Med
, vol.348
, Issue.3
, pp. 255
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Shmidt, M.3
Le Deist, F.4
Wulffraat, N.5
McIntyre, E.6
Radford, I.7
Villeval, J.L.8
Fraser, C.C.9
Cavazzana-Calvo, M.10
-
7
-
-
0034320366
-
A tumultuous year for gene therapy
-
(b) Verma, M.I. A tumultuous year for gene therapy. Mol. Ther. 2000, 2, 415-416.
-
(2000)
Mol. Ther.
, vol.2
, pp. 415-416
-
-
Verma, M.I.1
-
8
-
-
0343307124
-
Cationic lipids used in gene transfer
-
(a) Zabner, J. Cationic lipids used in gene transfer. Adv. Drug. Deliv. Rev., 1997, 27, 17-28.
-
(1997)
Adv. Drug. Deliv. Rev.
, vol.27
, pp. 17-28
-
-
Zabner, J.1
-
9
-
-
0001361923
-
Synthetic gene transfer vectors
-
(b) Berh, J.P. Synthetic gene transfer vectors. Acc. Chem. Res. 1993, 26, 274-278.
-
(1993)
Acc. Chem. Res.
, vol.26
, pp. 274-278
-
-
Berh, J.P.1
-
12
-
-
0035342007
-
-
Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications
-
(c) Estefand, R.; Tomalia, D.A. Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications. Drug Discovery Today, 2001, 6, 427-436.
-
(2001)
Drug Discovery Today
, vol.6
, pp. 427-436
-
-
Estefand, R.1
Tomalia, D.A.2
-
13
-
-
0021586266
-
A new class of polymers: Starburst-dendritic polymers
-
Tomalia, D.A.; Baker, H.; Dewald, J.; Hall, M.; Kallos, G.; Martin, S.; Roeck, J.; Ryder, J.; Smith, P. A new class of polymers: starburst-dendritic polymers. Polym. J, 1985, 17, 117-132.
-
(1985)
Polym. J
, vol.17
, pp. 117-132
-
-
Tomalia, D.A.1
Baker, H.2
Dewald, J.3
Hall, M.4
Kallos, G.5
Martin, S.6
Roeck, J.7
Ryder, J.8
Smith, P.9
-
14
-
-
0034005436
-
Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labeled polyamidoamine dendrimers in vivo
-
Malik, N., Wiwattanapatapee, R.; Klopsch, R.; Lorenz, K.; Frey, H.; Weener, J.W.; Meijer, E.W.; Paulus, W.; Duncan, R. Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labeled polyamidoamine dendrimers in vivo. J. Control. Release, 2000, 65, 133-148.
-
(2000)
J. Control. Release
, vol.65
, pp. 133-148
-
-
Malik, N.1
Wiwattanapatapee, R.2
Klopsch, R.3
Lorenz, K.4
Frey, H.5
Weener, J.W.6
Meijer, E.W.7
Paulus, W.8
Duncan, R.9
-
15
-
-
0038817081
-
Preparation of polymers with controlled molecular architecture. A new convergent approach to dendritic macromolecules
-
(a) Hawker, C.J.; Fréchet, J.M.J. Preparation of polymers with controlled molecular architecture. A new convergent approach to dendritic macromolecules. J. Am. Chem. Soc., 1990, 112, 7638.
-
(1990)
J. Am. Chem. Soc.
, vol.112
, pp. 7638
-
-
Hawker, C.J.1
Fréchet, J.M.J.2
-
16
-
-
0033997598
-
Water-soluble dendritic unimolecular micelles: Their potential as drug delivery agents
-
(b) Liu, M.; Kono, K.; Fréchet, J. M. J. Water-soluble dendritic unimolecular micelles: Their potential as drug delivery agents. J. Control. Release, 2000, 65, 121-131.
-
(2000)
J. Control. Release
, vol.65
, pp. 121-131
-
-
Liu, M.1
Kono, K.2
Fréchet, J.M.J.3
-
17
-
-
0032637389
-
Water-soluble dendrimer-poly(ethylene glycol) starlike conjugates as potential drug carriers
-
(c) Liu, M.; Kono, K.; Fréchet, J.M. Water-soluble dendrimer-poly(ethylene glycol) starlike conjugates as potential drug carriers. J. Polym. Sci., 1999, A37, 3492-3503.
-
(1999)
J. Polym. Sci.
, vol.A37
, pp. 3492-3503
-
-
Liu, M.1
Kono, K.2
Fréchet, J.M.3
-
18
-
-
0032804904
-
Preparation of water-Ssluble cationic phosphorus-containing dendrimers as DNA transfecting agents
-
(a) Loup, C.; Zanta, M.A.; Caminade, A.M.; Majoral, J.P.; Meunier, B. Preparation of water-Ssluble cationic phosphorus-containing dendrimers as DNA transfecting agents. Chem. Eur. J. 1999, 5, 3644-3650.
-
(1999)
Chem. Eur. J.
, vol.5
, pp. 3644-3650
-
-
Loup, C.1
Zanta, M.A.2
Caminade, A.M.3
Majoral, J.P.4
Meunier, B.5
-
19
-
-
18444366502
-
Water-soluble phosphorus-containing dendrimers
-
(b) Caminade, A.M.; Majoral, J.P. Water-soluble phosphorus-containing dendrimers. Progr. Polym. Sci. 2005, 30, 491-505.
-
(2005)
Progr. Polym. Sci.
, vol.30
, pp. 491-505
-
-
Caminade, A.M.1
Majoral, J.P.2
-
20
-
-
0034728692
-
An approach to glycerol dendrimers and pseudo-dendritic polyglycerols
-
(a) Haag, R.; Sunder, A.; Stumbé J.-F. An approach to glycerol dendrimers and pseudo-dendritic polyglycerols. J. Am. Chem. Soc., 2000, 122, 2954-2955.
-
(2000)
J. Am. Chem. Soc.
, vol.122
, pp. 2954-2955
-
-
Haag, R.1
Sunder, A.2
Stumbé, J.-F.3
-
21
-
-
0036183962
-
Dendritic polyglycerol: A new versatile biocompatible material
-
(b) Frey, H.; Haag, R. Dendritic polyglycerol: A new versatile biocompatible material. Rev. Mol. Biotech, 2002, 90, 257-267.
-
(2002)
Rev. Mol. Biotech
, vol.90
, pp. 257-267
-
-
Frey, H.1
Haag, R.2
-
22
-
-
0345708065
-
Glycerol and glycerol glycol glycodendrimers
-
(c) Boysen, M.M.K.; Elsner, K.; Sperling, O.; Lindhorts, T. K. Glycerol and glycerol glycol glycodendrimers. Eur. J. Org. Chem., 2003, 4376-4386.
-
(2003)
Eur. J. Org. Chem.
, pp. 4376-4386
-
-
Boysen, M.M.K.1
Elsner, K.2
Sperling, O.3
Lindhorts, T.K.4
-
23
-
-
1642340731
-
A surface-modified dendrimer set for potential applications as drug delivery vehicles: Synthesis, in vitro toxicity, and intracellular localization
-
Fuchs, S.; Kapp, T.; Otto, H.; Schöneberg T.; Franke, P.; Gust, R.; Schüter, D. A surface-modified dendrimer set for potential applications as drug delivery vehicles: synthesis, in vitro toxicity, and intracellular localization. Chem. Eur. J., 2004, 10, 1167-1192.
-
(2004)
Chem. Eur. J.
, vol.10
, pp. 1167-1192
-
-
Fuchs, S.1
Kapp, T.2
Otto, H.3
Schöneberg, T.4
Franke, P.5
Gust, R.6
Schüter, D.7
-
24
-
-
3543116767
-
In-vitro and invivo evaluation of melamine Dendrimer as a vehicle for drug delivery
-
Neerman, M.F.; Zhang, W.; Parrish, A.R.; Simanek, E. E. In-vitro and invivo evaluation of melamine Dendrimer as a vehicle for drug delivery. Int. J. Pharm., 2004, 281, 129-132.
-
(2004)
Int. J. Pharm.
, vol.281
, pp. 129-132
-
-
Neerman, M.F.1
Zhang, W.2
Parrish, A.R.3
Simanek, E.E.4
-
25
-
-
0035898469
-
Synthesis and characterization of linear, hyperbranched, and gendrimerlike polymers constituted of the same repeating unit
-
Merino, S.; Brauge, L.; Caminade, A.M.; Majoral, J.P.; Taton, D.; Gnanou, Y. Synthesis and characterization of linear, hyperbranched, and gendrimerlike polymers constituted of the same repeating unit. Chem. Eur. J., 2001, 7, 3095-3105.
-
(2001)
Chem. Eur. J.
, vol.7
, pp. 3095-3105
-
-
Merino, S.1
Brauge, L.2
Caminade, A.M.3
Majoral, J.P.4
Taton, D.5
Gnanou, Y.6
-
26
-
-
33846220323
-
Water-soluble carbosilane dendrimers: Synthesis, biocompatibility and complexation with oligonucleotides; Evaluation for medical applications
-
(a) Bermejo, J.F.; Ortega, P.; Chonco, L.; Eritja, R.; Samaniego, R.; Müllner, M.; de Jesús, E.; de la Mata, F.J.; Flores, J.C.; Gómez, R.; Muñoz-Fernández, M.A. Water-soluble carbosilane dendrimers: synthesis, biocompatibility and complexation with oligonucleotides; evaluation for medical applications. Chem. Eur. J. 2007, 13, 483-495.
-
(2007)
Chem. Eur. J.
, vol.13
, pp. 483-495
-
-
Bermejo, J.F.1
Ortega, P.2
Chonco, L.3
Eritja, R.4
Samaniego, R.5
Müllner, M.6
De Jesús, E.7
De La Mata, F.J.8
Flores, J.C.9
Gómez, R.10
Muñoz-Fernández, M.A.11
-
27
-
-
33645792528
-
Novel water-soluble carbosilane dendrimers: Synthesis and biocompatibility
-
(b) Ortega, P.; Bermejo, J.F.; Chonco, L.; de Jesús, E.; de la Mata, F.J.; Fernández, G.; Flores, J.C.; Gómez, R.; Serramía, M.J.; Muñoz-Fernández, M.A. Novel water-soluble carbosilane dendrimers: synthesis and biocompatibility. Eur. J. Inorg. Chem. 2006, 7, 1388-1396.
-
(2006)
Eur. J. Inorg. Chem.
, vol.7
, pp. 1388-1396
-
-
Ortega, P.1
Bermejo, J.F.2
Chonco, L.3
De Jesús, E.4
De La Mata, F.J.5
Fernández, G.6
Flores, J.C.7
Gómez, R.8
Serramía, M.J.9
Muñoz-Fernández, M.A.10
-
29
-
-
0000578961
-
Dendrimeric silanes
-
(b) van der Made, A.W.; van Leeuwen, P.W.N.M.; De Wilde, J.C.; Brandes, R.A.C. Dendrimeric silanes. Adv. Mater. 1993, 5, 466-468.
-
(1993)
Adv. Mater.
, vol.5
, pp. 466-468
-
-
Van Der Made, A.W.1
Van Leeuwen, P.W.N.M.2
De Wilde, J.C.3
Brandes, R.A.C.4
-
30
-
-
0027559752
-
Synthesis of novel carbosilane dendritic macromolecules
-
(c) Zhou, L.L.; Roovers, J. Synthesis of novel carbosilane dendritic macromolecules. Macromolecules 1993, 26, 963-968.
-
(1993)
Macromolecules
, vol.26
, pp. 963-968
-
-
Zhou, L.L.1
Roovers, J.2
-
31
-
-
0001370563
-
Synthesis of an organosilicon dendrimer containing 324 Si-H bonds
-
(d) Seyferth, D.; Son, D.Y.; Rheingold, A.L.; Ostrander, R.L. Synthesis of an organosilicon dendrimer containing 324 Si-H bonds. Organometallics 1994, 13, 2682-2690.
-
(1994)
Organometallics
, vol.13
, pp. 2682-2690
-
-
Seyferth, D.1
Son, D.Y.2
Rheingold, A.L.3
Ostrander, R.L.4
-
32
-
-
0000536459
-
-
G. R. Newkome, Ed.; JAI press Inc: Greenwich CT
-
(e) Cuadrado, I.; Morán, M.; Losada, J.; Casado, C.M.; Pascual, C.; Alonso, B.; Lobete, F. Advances in dendritic Macromolecules; G. R. Newkome, Ed.; JAI press Inc: Greenwich CT, 1996, 3, 151-195.
-
(1996)
Advances in Dendritic Macromolecules
, vol.3
, pp. 151-195
-
-
Cuadrado, I.1
Morán, M.2
Losada, J.3
Casado, C.M.4
Pascual, C.5
Alonso, B.6
Lobete, F.7
-
33
-
-
34250008790
-
Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins
-
(a) Chonco, L.; Bermejo, J.F.; Ortega, P.; Shcharbin, D.; Pedziwiatr, E.; Klajnert, B.; De la Mata, F.J.; Eritja, R.; Gómez, R.; Bryszewska, M.; Muñoz-Fernández, M.A. Water-soluble carbosilane dendrimers protect phosphorothioate oligonucleotides from binding to serum proteins. Org.& Biomol. Chem. 2007, 5, 1886-1893.
-
(2007)
Org.& Biomol. Chem.
, vol.5
, pp. 1886-1893
-
-
Chonco, L.1
Bermejo, J.F.2
Ortega, P.3
Shcharbin, D.4
Pedziwiatr, E.5
Klajnert, B.6
De La Mata, F.J.7
Eritja, R.8
Gómez, R.9
Bryszewska, M.10
Muñoz- Fernández, M.A.11
-
34
-
-
54949157770
-
Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV infected lymphocytes
-
(b) Weber, N.; Ortega, P.; Clemente, M.I; Shcharbin, D.; Bryszewska, M.; De la Mata, F.J.; Gómez, R.; Muñoz-Fernández, M.A. Characterization of carbosilane dendrimers as effective carriers of siRNA to HIV infected lymphocytes. J. Control. Release 2008, 132, 55-64.
-
(2008)
J. Control. Release
, vol.132
, pp. 55-64
-
-
Weber, N.1
Ortega, P.2
Clemente, M.I.3
Shcharbin, D.4
Bryszewska, M.5
De La Mata, F.J.6
Gómez, R.7
Muñoz-Fernández, M.A.8
-
35
-
-
63949086284
-
Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1α in early chemical hypoxia-mediated neurotoxicity
-
Posadas, I.; López-Hernández, B.; Clemente, M.I.; Jiménez, J.L.; Ortega, P.; De la Mata, F.J.; Gómez, R.; Muñoz-Fernández, M.A.; Cena, V. Highly efficient transfection of rat cortical neurons using carbosilane dendrimers unveils a neuroprotective role for HIF-1α in early chemical hypoxia-mediated neurotoxicity. Pharm. Res. 2009, 26, 1181-1191.
-
(2009)
Pharm. Res.
, vol.26
, pp. 1181-1191
-
-
Posadas, I.1
López-Hernández, B.2
Clemente, M.I.3
Jiménez, J.L.4
Ortega, P.5
De La Mata, F.J.6
Gómez, R.7
Muñoz-Fernández, M.A.8
Cena, V.9
-
36
-
-
74249093011
-
Waterstable ammonium-terminated carbosilane dendrimers as efficient antibacterial agents
-
Rasines, B.; Hernández-Ros, J.M.; de las Cuevas, N.; Copa-Patiño, J.L.; Soliveri, J.; Muñoz-Fernández, M.A.; Gómez, R.; De la Mata, F.J. Waterstable ammonium-terminated carbosilane dendrimers as efficient antibacterial agents. Dalton Trans., 2009, 40, 8704-8713.
-
(2009)
Dalton Trans.
, vol.40
, pp. 8704-8713
-
-
Rasines, B.1
Hernández-Ros, J.M.2
De Las Cuevas, N.3
Copa-Patiño, J.L.4
Soliveri, J.5
Muñoz-Fernández, M.A.6
Gómez, R.7
De La Mata, F.J.8
-
38
-
-
65249095262
-
Spanish HIV BioBank. The Spanish HIV BioBank: A model of cooperative HIV research
-
García-Merino, I.; de las Cuevas, N.; Jiménez, J.J.; Gallego, J.; Gómez C.; Prieto, C.; Serramía, M. A.; Lorente, R.; Muñoz-Fernández M.A.; Spanish HIV BioBank. The Spanish HIV BioBank: a model of cooperative HIV research. Retrovirology, 2009, 6
-
(2009)
Retrovirology
, vol.6
-
-
García-Merino, I.1
De Las Cuevas, N.2
Jiménez, J.J.3
Gallego, J.4
Gómez, C.5
Prieto, C.6
Serramía, M.A.7
Lorente, R.8
Muñoz- Fernández, M.A.9
-
40
-
-
0038580306
-
Insulin receptor substrate-4 signalling in quiescent rat hepatocytes and in regenerating rat liver
-
Escribano, O.; Fernández-Moreno, M.D.; Zueco, J.A.; Menor, C.; Fueyo, J.; Ropero, R.M.; Díaz-Laviada, I.; Román, I.D.; Guijarro, L.G. Insulin receptor substrate-4 signalling in quiescent rat hepatocytes and in regenerating rat liver. Hepatology, 2003, 37, 1461-1469.
-
(2003)
Hepatology
, vol.37
, pp. 1461-1469
-
-
Escribano, O.1
Fernández-Moreno, M.D.2
Zueco, J.A.3
Menor, C.4
Fueyo, J.5
Ropero, R.M.6
Díaz-Laviada, I.7
Román, I.D.8
Guijarro, L.G.9
-
41
-
-
34247597797
-
Role of insulin receptor substrate-4 in IGF-I-stimulated HEPG2 proliferation
-
Cuevas, E.P.; Escribano, O.; Chiloeches, A.; Ramírez Rubio, S.; Román, I.D.; Fernández-Moreno, M.D.; Guijarro, L.G. Role of insulin receptor substrate-4 in IGF-I-stimulated HEPG2 proliferation. J. Hepatol., 2007, 46, 1089-1098.
-
(2007)
J. Hepatol.
, vol.46
, pp. 1089-1098
-
-
Cuevas, E.P.1
Escribano, O.2
Chiloeches, A.3
Ramírez Rubio, S.4
Román, I.D.5
Fernández-Moreno, M.D.6
Guijarro, L.G.7
-
42
-
-
71749086711
-
RNAi-mediated silencing of insulin receptor substrate-4 enhances actinomycin d-and tumor necrosis factor-alpha-induced cell death in hepatocarcinoma cancer cell lines
-
Cuevas, E.P.; Escribano, O.; Monserrat, J.; Martínez-Botas, J.; Sánchez, M.G.; Chiloeches, A.; Hernández-Breijo, B.; Sánchez-Alonso, V.; Román, I.D.; Fernández-Moreno, M.D.; Guijarro, L.G. RNAi-Mediated Silencing of Insulin Receptor Substrate-4 Enhances Actinomycin D-and Tumor Necrosis Factor-alpha-Induced Cell Death in Hepatocarcinoma Cancer Cell Lines. J. Cell Biochem., 2009, 108, 1292-1301.
-
(2009)
J. Cell Biochem.
, vol.108
, pp. 1292-1301
-
-
Cuevas, E.P.1
Escribano, O.2
Monserrat, J.3
Martínez-Botas, J.4
Sánchez, M.G.5
Chiloeches, A.6
Hernández-Breijo, B.7
Sánchez-Alonso, V.8
Román, I.D.9
Fernández-Moreno, M.D.10
Guijarro, L.G.11
-
43
-
-
80054800966
-
Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma
-
Hernández-Breijo, B.; Monserrat, J.; Ramírez-Rubio, S.; Cuevas, E.P.; Vara, D.; Díaz-Laviada, I.; Fernández-Moreno, M.D.; Román, I.D.; Gisbert, J.P.; Guijarro, L.G. Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma. World Journal of Gastroenterology, 2011, 17(34), 3899-3911.
-
(2011)
World Journal of Gastroenterology
, vol.17
, Issue.34
, pp. 3899-3911
-
-
Hernández-Breijo, B.1
Monserrat, J.2
Ramírez-Rubio, S.3
Cuevas, E.P.4
Vara, D.5
Díaz-Laviada, I.6
Fernández-Moreno, M.D.7
Román, I.D.8
Gisbert, J.P.9
Guijarro, L.G.10
|