Imaging studies for diagnosing Graves' orbitopathy and dysthyroid optic neuropathy

Clinics

Volumn 67, Issue 11, 2012, Pages 1327-1334

  Gonçalves, Allan C Pieroni ^a   Gebrim, Eloísa M M S ^a   Monteiro, Mário L R ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Color doppler ultrasonography; Graves' ophthalmopathy; Magnetic resonance imaging; Multidetector computed tomography; Optic nerve diseases; Ultrasonography

Indexed keywords

DIAGNOSTIC IMAGING; GRAVES DISEASE; HUMAN; METHODOLOGY; OPTIC NERVE DISEASE; REVIEW;

DIAGNOSTIC IMAGING; GRAVES DISEASE; HUMANS; OPTIC NERVE DISEASES;

EID: 84870400956     PISSN: 18075932     EISSN: None     Source Type: Journal    
DOI: 10.6061/clinics/2012(11)18     Document Type: Review

References (81)

1. Smith TJ. Pathogenesis of Graves' orbitopathy: a 2010 update. J Endocrinol Invest. 2010;33(6):414-421.
2. Bahn RS, Heufelder AE. Pathogenesis of Graves' ophthalmopathy. N Engl J Med. 1993;329(20):1468-1475.
3. Heufelder AE. Pathogenesis of ophthalmopathy in autoimmune thyroid disease. Rev Endocr Metab Disord. 2000 Jan;1(1-2):87-95, http://dx.doi.org/10.1023/A:1010020621687.
4. Kahaly GJ. Imaging in thyroid-associated orbitopathy. Eur J Endocrinol. 2001;145(2):107-118, http://dx.doi.org/10.1530/eje.0.1450107.
5. Naik VM, Naik MN, Goldberg RA, Smith TJ, Douglas RS. Immunopathogenesis of thyroid eye disease: emerging paradigms. Surv Ophthalmol. 2010;55(3):215-226, http://dx.doi.org/10.1016/j.survophthal.2009.06.009.
6. Feldon SE. Graves' ophthalmopathy. Is it really thyroid disease? Arch Intern Med. 1990;150(5):948-950, http://dx.doi.org/10.1001/archinte.1990.00390170010003.
7. Bartley GB, Gorman CA. Diagnostic criteria for Graves' ophthalmopathy. Am J Ophthalmol. 1995;119(6):792-795.
8. Bartley GB. The epidemiologic characteristics and clinical course of ophthalmopathy associated with autoimmune thyroid disease in Olmsted County, Minnesota. Trans Am Ophthalmol Soc. 1994;92:477-588.
9. Neigel JM, Rootman J, Belkin RI, Nugent RA, Drance SM, Beattie CW, et al. Dysthyroid optic neuropathy. The crowded orbital apex syndrome. Ophthalmology. 1988;95(11):1515-1521.
10. Trobe JD, Glaser JS, Laflamme P. Dysthyroid optic neuropathy. Clinical profile and rationale for management. Arch Ophthalmol. 1978;96(7):1199-1209, http://dx.doi.org/10.1001/archopht.1978.03910060033007.
11. Day RM, Carroll FD. Optic nerve involvement associated with thyroid dysfunction. Trans Am Ophthalmol Soc. 1961;59:220-238.
12. Kazim M, Trokel SL, Acaroglu G, Elliott A. Reversal of dysthyroid optic neuropathy following orbital fat decompression. Br J Ophthalmol. 2000;84(6):600-605, http://dx.doi.org/10.1136/bjo.84.6.600.
13. Dosso A, Safran AB, Sunaric G, Burger A. Anterior ischemic optic neuropathy in Graves' disease. J Neuroophthalmol. 1994;14(3):170-174.
14. Feldon SE, Muramatsu S, Weiner JM. Clinical classification of Graves' ophthalmopathy. Identification of risk factors for optic neuropathy. Arch Ophthalmol. 1984;102(10):1469-1472, http://dx.doi.org/10.1001/archopht.1984.01040031189015.
15. Dayan CM, Dayan MR. Dysthyroid optic neuropathy: a clinical diagnosis or a definable entity? Br J Ophthalmol. 2007 Apr;91(4):409-410, http://dx.doi.org/10.1136/bjo.2006.110932.
16. Kirsch E, von Arx G, Hammer B. Imaging in Graves' orbitopathy. Orbit. 2009;28(4):219-225.
17. Giaconi JA, Kazim M, Rho T, Pfaff C. CT scan evidence of dysthyroid optic neuropathy. Ophthal Plast Reconstr Surg. 2002 May;18(3):177-182.
18. Kirsch E, Hammer B, von Arx G. Graves' orbitopathy: current imaging procedures. Swiss Med Wkly. 2009;139(43-44):618-623.
19. Kalender WA. CT: the unexpected evolution of an imaging modality. Eur Radiol. 2005;15(Suppl 4):D21-D24.
20. Flohr T, Stierstorfer K, Bruder H, Simon J, Schaller S. New technical developments in multislice CT-Part 1: Approaching isotropic resolution with sub-millimeter 16-slice scanning. Rofo. 2002;174(7):839-845, http://dx.doi.org/10.1055/s-2002-32692.
21. Hosten N, Sander B, Cordes M, Schubert CJ, Schorner W, Felix R. Graves ophthalmopathy: MR imaging of the orbits. Radiology. 1989;172(3):759-762.
22. Eyer MK, Brandestini MA, Phillips DJ, Baker DW. Color digital echo/ Doppler image presentation. Ultrasound Med Biol. 1981;7(1):21-31, http://dx.doi.org/10.1016/0301-5629(81)90019-3.
23. De Potter P. Advances in imaging in oculoplastics. Curr Opin Ophthalmol. 2001;12(5):342-346, http://dx.doi.org/10.1097/00055735-200110000-00003.
24. Belden CJ, Abbitt PL, Beadles KA. Color Doppler US of the orbit. Radiographics. 1995;15(3):589-608.
25. Alp MN, Ozgen A, Can I, Cakar P, Gunalp I. Colour Doppler imaging of the orbital vasculature in Graves' disease with computed tomographic correlation. Br J Ophthalmol. 2000;84(9):1027-1030, http://dx.doi.org/10.1136/bjo.84.9.1027.
26. Monteiro ML, Moritz RB, Angotti Neto H, Benabou JE. Color Doppler imaging of the superior ophthalmic vein in patients with Graves' orbitopathy before and after treatment of congestive disease. Clinics. 2011;66(8):1329-1334.
27. Frueh BR. Graves' eye disease: orbital compliance and other physical measurements. Trans Am Ophthalmol Soc. 1984;82:492-598.
28. Wiersinga WM, Smit T, van der Gaag R, Koornneef L. Temporal relationship between onset of Graves' ophthalmopathy and onset of thyroidal Graves' disease. J Endocrinol Invest. 1988;11(8):615-619.
29. Sridama V, DeGroot LJ. Treatment of Graves' disease and the course of ophthalmopathy. Am J Med. 1989;87(1):70-73, http://dx.doi.org/10.1016/S0002-9343(89)80485-1.
30. Kendler DL, Lippa J, Rootman J. The initial clinical characteristics of Graves' orbitopathy vary with age and sex. Arch Ophthalmol. 1993;111(2):197-201, http://dx.doi.org/10.1001/archopht.1993.1090020051022.
31. Trokel SL, Jakobiec FA. Correlation of CT scanning and pathologic features of ophthalmic Graves' disease. Ophthalmology. 1981;88(6):553-564.
32. Nugent RA, Belkin RI, Neigel JM, Rootman J, Robertson WD, Spinelli J, et al. Graves orbitopathy: correlation of CT and clinical findings. Radiology. 1990;177(3):675-682.
33. Ozgen A, Ariyurek M. Normative measurements of orbital structures using CT. AJR Am J Roentgenol. 1998;170(4):1093-1096.
34. Forbes G, Gorman CA, Gehring D, Baker HL, Jr. Computer analysis of orbital fat and muscle volumes in Graves ophthalmopathy. AJNR Am J Neuroradiol. 1983;4(3):737-740.
35. Patrinely JR, Osborn AG, Anderson RL, Whiting AS. Computed tomographic features of nonthyroid extraocular muscle enlargement. Ophthalmology. 1989;96(7):1038-1047.
36. Enzmann DR, Donaldson SS, Kriss JP. Appearance of Graves' disease on orbital computed tomography. J Comput Assist Tomogr. 1979;3(6):815-819.
37. Yoshikawa K, Higashide T, Nakase Y, Inoue T, Inoue Y, Shiga H. Role of rectus muscle enlargement in clinical profile of dysthyroid ophthalmopathy. Jpn J Ophthalmol. 1991;35(2):175-181.
38. Dabbs CB, Kline LB. Big muscles and big nerves. Surv Ophthalmol. 1997;42(3):247-254, http://dx.doi.org/10.1016/S0039-6257(97)00094-5.
39. Dresner SC, Rothfus WE, Slamovits TL, Kennerdell JS, Curtin HD. Computed tomography of orbital myositis. AJR Am J Roentgenol. 1984;143(3):671-674.
40. Rothfus WE, Curtin HD. Extraocular muscle enlargement: a CT review. Radiology. 1984;151(3):677-681.
41. Ben Simon GJ, Syed HM, Douglas R, McCann JD, Goldberg RA. Extraocular muscle enlargement with tendon involvement in thyroidassociated orbitopathy. Am J Ophthalmol. 2004;137(6):1145-1147, http://dx.doi.org/10.1016/j.ajo.2004.01.033.
42. Sabetti L, Toscano A, Specchia G, Balestrazzi E. Alterations of the internal reflectivity of extra-ocular muscles associated with several clinical stages of Graves' ophthalmopathy. Ophthalmologica. 1998; 212(Suppl 1):107-109.
43. Imbrasiene D, Jankauskiene J, Stanislovaitiene D. Ultrasonic measurement of ocular rectus muscle thickness in patients with Graves' ophthalmopathy. Medicina (Kaunas). 2010;46(7):472-476.
44. Villadolid MC, Yokoyama N, Izumi M, Nishikawa T, Kimura H, Ashizawa K, et al. Untreated Graves' disease patients without clinical ophthalmopathy demonstrate a high frequency of extraocular muscle (EOM) enlargement by magnetic resonance. J Clin Endocrinol Metab. 1995;80(9):2830-3833, http://dx.doi.org/10.1210/jc.80.9.2830.
45. Kumar S, Coenen MJ, Scherer PE, Bahn RS. Evidence for enhanced adipogenesis in the orbits of patients with Graves' ophthalmopathy. J Clin Endocrinol Metab. 2004;89(2):930-935, http://dx.doi.org/10.1210/jc.2003-031427.
46. Forbes G, Gorman CA, Brennan MD, Gehring DG, Ilstrup DM, Earnest Ft. Ophthalmopathy of Graves' disease: computerized volume measurements of the orbital fat and muscle. AJNR Am J Neuroradiol. 1986;7(4):651-656.
47. Jacobson DH, Gorman CA. Endocrine ophthalmopathy: current ideas concerning etiology, pathogenesis, and treatment. Endocr Rev. 1984 Spring;5(2):200-220, http://dx.doi.org/10.1210/edrv-5-2-200.
48. Peyster RG, Ginsberg F, Silber JH, Adler LP. Exophthalmos caused by excessive fat: CT volumetric analysis and differential diagnosis. AJR Am J Roentgenol. 1986;146(3):459-464.
49. Susac JO, Martins AN, Robinson B, Corrigan DF. False diagnosis of orbital apex tumor by CAT scan in thyroid eye disease. Ann Neurol. 1977;1(4):397-398, http://dx.doi.org/10.1002/ana.410010412.
50. Enzmann D, Marshal WH, Jr., Rosenthal AR, Kriss JP. Computed tomography in Graves' ophthalmopathy. Radiology. 1976;118(3):615-620.
51. Harris MA, Realini T, Hogg JP, Sivak-Callcott JA. CT dimensions of the lacrimal gland in Graves orbitopathy. Ophthal Plast Reconstr Surg. 2012;28(1):69-72, http://dx.doi.org/10.1097/IOP.0b013e31823c4a3a.
52. Barrett L, Glatt HJ, Burde RM, Gado MH. Optic nerve dysfunction in thyroid eye disease: CT. Radiology. 1988;167(2):503-507.
53. Le Moli R, Pluchino A, Muscia V, Regalbuto C, Luciani B, Squatrito S, et al. Graves' orbitopathy: extraocular muscle/total orbit area ratio is positively related to the Clinical Activity Score. Eur J Ophthalmol. 2012;22(3):301-308, http://dx.doi.org/10.5301/ejo.5000018.
54. Rodriguez-Gonzalez N, Perez-Rico C, Lopez-Para Gimenez R, Arevalo-Serrano J, Del Amo Garcia B, Calzada Domingo L, et al. [Short-tau inversion-recovery (STIR) sequence magnetic resonance imaging evaluation of orbital structures in Graves' orbitopathy]. Arch Soc Esp Oftalmol. 2011;86(11):351-357.
55. Kirsch EC, Kaim AH, De Oliveira MG, von Arx G. Correlation of signal intensity ratio on orbital MRI-TIRM and clinical activity score as a possible predictor of therapy response in Graves' orbitopathy-a pilot study at 1.5 T. Neuroradiology. 2010;52(2):91-97, http://dx.doi.org/10.1007/s00234-009-0590-z.
56. Cakirer S, Cakirer D, Basak M, Durmaz S, Altuntas Y, Yigit U. Evaluation of extraocular muscles in the edematous phase of Graves ophthalmopathy on contrast-enhanced fat-suppressed magnetic resonance imaging. J Comput Assist Tomogr. 2004;28(1):80-86, http://dx.doi.org/10.1097/00004728-200401000-00013.
57. Mourits MP, Prummel MF, Wiersinga WM, Koornneef L. Clinical activity score as a guide in the management of patients with Graves' ophthalmopathy. Clin Endocrinol (Oxf). 1997;47(1):9-14, http://dx.doi.org/10.1046/j.1365-2265.1997.2331047.x.
58. Dolman PJ, Rootman J. VISA Classification for Graves orbitopathy. Ophthal Plast Reconstr Surg. 2006;22(5):319-324.
59. Vlainich AR, Romaldini JH, Pedro AB, Farah CS, Sinisgalli CA, Jr. Ultrasonography compared to magnetic resonance imaging in thyroidassociated Graves' ophthalmopathy. Arq Bras Endocrinol Metabol. 2011;55(3):184-188, http://dx.doi.org/10.1590/S0004-27302011000300002.
60. Mayer EJ, Fox DL, Herdman G, Hsuan J, Kabala J, Goddard P, et al. Signal intensity, clinical activity and cross-sectional areas on MRI scans in thyroid eye disease. Eur J Radiol. 2005;56(1):20-24, http://dx.doi.org/10.1016/j.ejrad.2005.03.027.
61. Tachibana S, Murakami T, Noguchi H, Noguchi Y, Nakashima A, Ohyabu Y, et al. Orbital magnetic resonance imaging combined with clinical activity score can improve the sensitivity of detection of disease activity and prediction of response to immunosuppressive therapy for Graves' ophthalmopathy. Endocr J. 2010;57(10):853-861, http://dx.doi.org/10.1507/endocrj.K10E-156.
62. Prummel MF, Suttorp-Schulten MS, Wiersinga WM, Verbeek AM, Mourits MP, Koornneef L. A new ultrasonographic method to detect disease activity and predict response to immunosuppressive treatment in Graves ophthalmopathy. Ophthalmology. 1993;100(4):556-561.
63. Fledelius HC, Zimmermann-Belsing T, Feldt-Rasmussen U. Ultrasonically measured horizontal eye muscle thickness in thyroid associated orbitopathy: cross-sectional and longitudinal aspects in a Danish series. Acta Ophthalmol Scand. 2003;81(2):143-150, http://dx.doi.org/10.1034/j.1600-0420.2003.00037.x.
64. Benning H, Lieb W, Kahaly G, Grehn F. [Color duplex ultrasound findings in patients with endocrine orbitopathy]. Ophthalmologe. 1994;91(1):20-25.
65. Somer D, Ozkan SB, Ozdemir H, Atilla S, Soylev MF, Duman S. Colour Doppler imaging of superior ophthalmic vein in thyroid-associated eye disease. Jpn J Ophthalmol. 2002;46(3):341-345, http://dx.doi.org/10.1016/S0021-5155(02)00485-9.
66. Monteiro ML, Angotti-Neto H, Benabou JE, Betinjane AJ. Color Doppler imaging of the superior ophthalmic vein in different clinical forms of Graves' orbitopathy. Jpn J Ophthalmol. 2008;52(6):483-488, http://dx.doi.org/10.1007/s10384-008-0594-y.
67. Aguirre-Balsalobre F, Mengual-Verdu E, Munoz-Acosta JM, Martinez-Caballero A, Caballero-Carpena O, Hueso-Abacens JR. [Octreotide scintigraphy in thyroid orbitopathy]. Arch Soc Esp Oftalmol. 2007;82(3):133-139.
68. Kahaly GJ, Forster GJ. Somatostatin receptor scintigraphy in thyroid eye disease. Thyroid. 1998;8(6):549-552, http://dx.doi.org/10.1089/thy.1998.8.549.
69. Anderson RL, Tweeten JP, Patrinely JR, Garland PE, Thiese SM. Dysthyroid optic neuropathy without extraocular muscle involvement. Ophthalmic Surg. 1989;20(8):568-574.
70. McKeag D, Lane C, Lazarus JH, Baldeschi L, Boboridis K, Dickinson AJ, et al. Clinical features of dysthyroid optic neuropathy: a European Group on Graves' Orbitopathy (EUGOGO) survey. Br J Ophthalmol. 2007;91(4):455-458, http://dx.doi.org/10.1136/bjo.2006.094607.
71. Monteiro ML, Goncalves AC, Silva CT, Moura JP, Ribeiro CS, Gebrim EM. Diagnostic ability of Barrett's index to detect dysthyroid optic neuropathy using multidetector computed tomography. Clinics. 2008;63(3):301-306, http://dx.doi.org/10.1590/S1807-59322008000300003.
72. Ozgen A, Alp MN, Ariyurek M, Tutuncu NB, Can I, Gunalp I. Quantitative CT of the orbit in Graves' disease. Br J Radiol. 1999;72(860):757-762.
73. Chan LL, Tan HE, Fook-Chong S, Teo TH, Lim LH, Seah LL. Graves ophthalmopathy: the bony orbit in optic neuropathy, its apical angular capacity, and impact on prediction of risk. AJNR Am J Neuroradiol. 2009;30(3):597-602, http://dx.doi.org/10.3174/ajnr.A1413.
74. Birchall D, Goodall KL, Noble JL, Jackson A. Graves ophthalmopathy: intracranial fat prolapse on CT images as an indicator of optic nerve compression. Radiology. 1996;200(1):123-127.
75. Goncalves AC, Silva LN, Gebrim EM, Monteiro ML. Quantification of Orbital Apex Crowding for Screening of Dysthyroid Optic Neuropathy Using Multidetector CT. AJNR Am J Neuroradiol. 2012; 33(8):1602-1607.
76. Kennerdell JS, Rosenbaum AE, El-Hoshy MH. Apical optic nerve compression of dysthyroid optic neuropathy on computed tomography. Arch Ophthalmol. 1981;99(5):807-809, http://dx.doi.org/10.1001/archopht.1981.03930010807002.
77. Feldon SE, Lee CP, Muramatsu SK, Weiner JM. Quantitative computed tomography of Graves' ophthalmopathy. Extraocular muscle and orbital fat in development of optic neuropathy. Arch Ophthalmol. 1985;103(2):213-215, http://dx.doi.org/10.1001/archopht.1985.01050020065021.
78. Chapman VM, Grottkau BE, Albright M, Salamipour H, Jaramillo D. Multidetector computed tomography of pediatric lateral condylar fractures. J Comput Assist Tomogr. 2005;29(6):842-846, http://dx.doi.org/10.1097/01.rct.0000175504.64707.e3,-1,xxx/64707.e3.
79. Goncalves AC, Silva LN, Gebrim EM, Matayoshi S, Monteiro ML. Predicting dysthyroid optic neuropathy using computed tomography volumetric analysis of orbital structures. Clinics. 2012;67(8):891-896, http://dx.doi.org/10.6061/clinics/2012(08)06.
80. Dodds NI, Atcha AW, Birchall D, Jackson A. Use of high-resolution MRI of the optic nerve in Graves' ophthalmopathy. Br J Radiol. 2009;82(979):541-544, http://dx.doi.org/10.1259/bjr/56958444.
81. Nakase Y, Osanai T, Yoshikawa K, Inoue Y. Color Doppler imaging of orbital venous flow in dysthyroid optic neuropathy. Jpn J Ophthalmol. 1994;38(1):80-86.