Identification and analysis of the human hyaluronan synthase 1 gene promoter reveals Smad3- and Sp3-mediated transcriptional induction

Matrix Biology

Volumn 31, Issue 7-8, 2012, Pages 373-379

  Chen, Long ^a,b   Neville, Rachel D ^a,c   Michael, Daryn R ^a   Martin, John ^a,c   Luo, Dong Dong ^a   Thomas, David W ^c,d   Phillips, Aled O ^a,c   Bowen, Timothy ^a,c  

^a CARDIFF UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^b AFFILIATED ZHONGDA HOSPITAL OF SOUTHEAST UNIVERSITY   (China)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Dermal fibroblasts; Hyaluronan synthase 1 gene; Renal fibrosis; Smad3; Sp3; Transcription

Indexed keywords

COMPLEMENTARY DNA; INTERLEUKIN 1BETA; LUCIFERASE; MESSENGER RNA; NUCLEOTIDE; SMAD2 PROTEIN; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; TRANSFORMING GROWTH FACTOR BETA1;

ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVITY; ENZYME ASSAY; EXON; GENE; GENE AMPLIFICATION; GENE IDENTIFICATION; GENE SEQUENCE; GENE VECTOR; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HYALURONAN SYNTHASE 1 GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION INITIATION; UPREGULATION;

BASE SEQUENCE; DNA PRIMERS; DNA, COMPLEMENTARY; ELECTROPHORESIS, AGAR GEL; EXTRACELLULAR MATRIX PROTEINS; GENE EXPRESSION REGULATION; GLUCURONOSYLTRANSFERASE; HUMANS; INTERLEUKIN-1BETA; LUCIFERASES; MOLECULAR SEQUENCE DATA; NUCLEIC ACID AMPLIFICATION TECHNIQUES; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS, DNA; SMAD3 PROTEIN; SP3 TRANSCRIPTION FACTOR;

MAMMALIA;

EID: 84870391697     PISSN: 0945053X     EISSN: 15691802     Source Type: Journal    
DOI: 10.1016/j.matbio.2012.10.002     Document Type: Article

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