Novel fluorescent cephalosporins: Synthesis, antimicrobial activity and photodynamic inactivation of antibiotic resistant bacteria

European Journal of Medicinal Chemistry

Volumn 59, Issue , 2013, Pages 150-159

  Xiao, Jian Min ^a   Feng, Lei ^a   Zhou, Li Sheng ^a   Gao, Hui Zhou ^a   Zhang, Yi Lin ^a   Yang, Ke Wu ^a  

^a NORTHWEST UNIVERSITY   (China)

Author keywords

Antimicrobial activity; Fluorescent cephalosporins; Photoinactivation; Substrate

Indexed keywords

8 OXO 3 [[4 (2 OXO 2H CHROMENE 3 CARBOXAMIDO)PHENYLTHIO]METHYL] 7 [2 (THIOPHEN 2 YL)ACETAMIDO] 5 THIA 1 AZA BICYCLE[4.2.0]OCT 2 ENE 2 CARBOXYLIC ACID; 8 OXO 3 [[4 (3 OXO 3H BENZOL[F]CHROMENE 2 CARBOXAMIDO)PHENYLTHIO]METHYL] 7 [2 (THIOPEN 2 YL)ACETAMIDO] 5 THIA 1 AZA BICYCLO[4.2.0]OCT 2 ENE 2 CARBOXYLIC ACID; BETA LACTAMASE; CARBOXYLIC ACID DERIVATIVE; CEPHALOSPORIN DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIMICROBIAL ACTIVITY; ARTICLE; BINDING AFFINITY; BIOLOGICAL ACTIVITY; CARBON NUCLEAR MAGNETIC RESONANCE; CELL DEATH; COLONY FORMING UNIT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; FLUORESCENCE; FLUORESCENCE SPECTROSCOPY; IN VITRO STUDY; KLEBSIELLA PNEUMONIAE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHOTODYNAMICS; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; STEADY STATE; ULTRAVIOLET RADIATION; ULTRAVIOLET SPECTROSCOPY;

ANTI-INFECTIVE AGENTS; BACTERIA; CEPHALOSPORINS; DRUG RESISTANCE, BACTERIAL; FLUORESCENT DYES; LIGHT; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE;

EID: 84870381388     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2012.11.019     Document Type: Article

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