Glucose Metabolic Trapping in Mouse Arteries: Nonradioactive Assay of Atherosclerotic Plaque Inflammation Applicable to Drug Discovery

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Conway, Richard G ^a   Chernet, Eyassu ^a   de Rosa, David C ^a   Benschop, Robert J ^a   Need, Anne B ^a   Collins, Emily C ^a   Bean, James S ^a   Kalbfleisch, J Michael ^a   Rekhter, Mark D ^a  

^a ELI LILLY AND COMPANY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CHOLESTEROL ESTER; FLUORODEOXYGLUCOSE 6 PHOSPHATE; FLUORODEOXYGLUCOSE F 18; GLUCOSE; LIVER X RECEPTOR AGONIST; N (2,2,2 TRIFLUOROETHYL) N [4 [2,2,2 TRIFLUORO 1 HYDROXY 1 (TRIFLUOROMETHOXY)ETHYL]PHENYL]BENZENESULFONAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATHEROSCLEROTIC PLAQUE; CARBOHYDRATE ANALYSIS; CAROTID ARTERY LIGATION; CELL COUNT; CLINICAL ASSESSMENT; CONTROLLED STUDY; CORONARY ARTERY; DIAGNOSTIC IMAGING; DIET SUPPLEMENTATION; DISEASE ASSOCIATION; GLUCOSE METABOLIC TRAPPING; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LIQUID CHROMATOGRAPHY; MACROPHAGE; MASS SPECTROMETRY; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROTEIN DEGRADATION; QUANTITATIVE ANALYSIS;

ANIMALS; APOLIPOPROTEINS E; ARTERIES; ATHEROSCLEROSIS; CAROTID ARTERIES; CELL LINE; CHEMISTRY, PHARMACEUTICAL; CHOLESTEROL; CHROMATOGRAPHY, LIQUID; DIAGNOSTIC IMAGING; DISEASE MODELS, ANIMAL; DRUG DESIGN; GLUCOSE; GLUCOSE-6-PHOSPHATE; HUMANS; HYDROCARBONS, FLUORINATED; IONS; MASS SPECTROMETRY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; ORPHAN NUCLEAR RECEPTORS; PLAQUE, ATHEROSCLEROTIC; POSITRON-EMISSION TOMOGRAPHY; SULFONAMIDES; TIME FACTORS;

MUS;

EID: 84870358484     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0050349     Document Type: Article

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