메뉴 건너뛰기




Volumn 4, Issue 3, 2011, Pages 190-198

F-18-FDG Imaging for Atherosclerotic Plaque Characterization

Author keywords

Atherosclerosis; FDG PET; Inflammation; Macrophages; Plaque

Indexed keywords


EID: 84855463970     PISSN: 19419066     EISSN: 19419074     Source Type: Journal    
DOI: 10.1007/s12410-011-9083-7     Document Type: Review
Times cited : (7)

References (62)
  • 1
    • 0021228785 scopus 로고
    • Incidence and prognosis of unrecognized myocardial infarction. An update on the framingham study
    • Kannel WB, Abbott RD. Incidence and prognosis of unrecognized myocardial infarction. An update on the framingham study. N Engl J Med. 1984; 311: 1144-7.
    • (1984) N Engl J Med , vol.311 , pp. 1144-1147
    • Kannel, W.B.1    Abbott, R.D.2
  • 2
    • 0023722916 scopus 로고
    • Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?
    • Little WC, Constantinescu M, Applegate RJ, et al. Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease? Circulation. 1988; 78: 1157-66.
    • (1988) Circulation , vol.78 , pp. 1157-1166
    • Little, W.C.1    Constantinescu, M.2    Applegate, R.J.3
  • 3
    • 0026524594 scopus 로고
    • Relation of the site of acute myocardial infarction to the most severe coronary arterial stenosis at prior angiography
    • Giroud D, Li JM, Urban P, et al. Relation of the site of acute myocardial infarction to the most severe coronary arterial stenosis at prior angiography. Am J Cardiol. 1992; 69: 729-32.
    • (1992) Am J Cardiol , vol.69 , pp. 729-732
    • Giroud, D.1    Li, J.M.2    Urban, P.3
  • 4
    • 0034651992 scopus 로고    scopus 로고
    • Extent and direction of arterial remodeling in stable versus unstable coronary syndromes: an intravascular ultrasound study
    • Schoenhagen P, Ziada KM, Kapadia SR, et al. Extent and direction of arterial remodeling in stable versus unstable coronary syndromes: an intravascular ultrasound study. Circulation. 2000; 101: 598-603.
    • (2000) Circulation , vol.101 , pp. 598-603
    • Schoenhagen, P.1    Ziada, K.M.2    Kapadia, S.R.3
  • 5
    • 0028876102 scopus 로고
    • Our preoccupation with coronary luminology. The dissociation between clinical and angiographic findings in ischemic heart disease
    • Topol EJ, Nissen SE. Our preoccupation with coronary luminology. The dissociation between clinical and angiographic findings in ischemic heart disease. Circulation. 1995; 92: 2333-42.
    • (1995) Circulation , vol.92 , pp. 2333-2342
    • Topol, E.J.1    Nissen, S.E.2
  • 6
    • 57849117801 scopus 로고    scopus 로고
    • Atherosclerosis--an immune disease: the anitschkov lecture 2007
    • This article reviewed the current pathophysiological idea of atherosclerosis as an immune disease on the basis of patient studies (including epidemiological cohorts) and experimental animal models
    • • Hansson GK: Atherosclerosis--an immune disease: the anitschkov lecture 2007. Atherosclerosis. 2009; 202: 2-10. This article reviewed the current pathophysiological idea of atherosclerosis as an immune disease on the basis of patient studies (including epidemiological cohorts) and experimental animal models.
    • (2009) Atherosclerosis , vol.202 , pp. 2-10
    • Hansson, G.K.1
  • 7
    • 77952303924 scopus 로고    scopus 로고
    • Matrix-metalloproteinases as imaging targets for inflammatory activity in atherosclerotic plaques
    • This review article is about molecular targets in atherosclerotic plaques, particularly matrix-metalloproteinases. Besides rather unspecific FDG-PET imaging, the development of target-specific and/or cell-specific molecular imaging promises substantial clinical innovations and improvements
    • •• Schäfers M, Schober O, Hermann S. Matrix-metalloproteinases as imaging targets for inflammatory activity in atherosclerotic plaques. J Nucl Med. 2010; 51: 663-6. This review article is about molecular targets in atherosclerotic plaques, particularly matrix-metalloproteinases. Besides rather unspecific FDG-PET imaging, the development of target-specific and/or cell-specific molecular imaging promises substantial clinical innovations and improvements.
    • (2010) J Nucl Med , vol.51 , pp. 663-666
    • Schäfers, M.1    Schober, O.2    Hermann, S.3
  • 9
    • 55249098633 scopus 로고    scopus 로고
    • Integrated PET/CT in the assessment of etiology and viability in ischemic heart failure
    • Sheikine Y, Di Carli MF. Integrated PET/CT in the assessment of etiology and viability in ischemic heart failure. Curr Heart Fail Rep. 2008; 5: 136-42.
    • (2008) Curr Heart Fail Rep , vol.5 , pp. 136-142
    • Sheikine, Y.1    Di Carli, M.F.2
  • 11
    • 0020463022 scopus 로고
    • Granulocytes utilize different energy sources for movement and phagocytosis
    • Weisdorf DJ, Craddock PR, Jacob HS. Granulocytes utilize different energy sources for movement and phagocytosis. Inflammation. 1982; 6: 245-56.
    • (1982) Inflammation , vol.6 , pp. 245-256
    • Weisdorf, D.J.1    Craddock, P.R.2    Jacob, H.S.3
  • 12
    • 66749187756 scopus 로고    scopus 로고
    • Novel concepts in atherogenesis: Angiogenesis and hypoxia in atherosclerosis
    • Sluimer JC, Daemen MJ. Novel concepts in atherogenesis: Angiogenesis and hypoxia in atherosclerosis. J Pathol. 2009; 218: 7-29.
    • (2009) J Pathol , vol.218 , pp. 7-29
    • Sluimer, J.C.1    Daemen, M.J.2
  • 13
    • 4043176293 scopus 로고    scopus 로고
    • Imaging the vulnerable plaque: a scintillating light at the end of the tunnel?
    • Strauss HW, Dunphy M, Tokita N. Imaging the vulnerable plaque: a scintillating light at the end of the tunnel? J Nucl Med. 2004; 45: 1106-7.
    • (2004) J Nucl Med , vol.45 , pp. 1106-1107
    • Strauss, H.W.1    Dunphy, M.2    Tokita, N.3
  • 14
    • 0033595121 scopus 로고    scopus 로고
    • Glucose transporters and insulin action-implications for insulin resistance and diabetes mellitus
    • Shepherd PR, Kahn BB. Glucose transporters and insulin action-implications for insulin resistance and diabetes mellitus. N Engl J Med. 1999; 341: 248-57.
    • (1999) N Engl J Med , vol.341 , pp. 248-257
    • Shepherd, P.R.1    Kahn, B.B.2
  • 15
    • 0023029455 scopus 로고
    • Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages
    • Newsholme P, Curi R, Gordon S, Newsholme EA. Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages. Biochem J. 1986; 239: 121-5.
    • (1986) Biochem J , vol.239 , pp. 121-125
    • Newsholme, P.1    Curi, R.2    Gordon, S.3    Newsholme, E.A.4
  • 16
    • 20844442622 scopus 로고    scopus 로고
    • [18F]FDG uptake and PCNA, glut-1, and hexokinase-II expressions in cancers and inflammatory lesions of the lung
    • Mamede M, Higashi T, Kitaichi M, et al. [18F]FDG uptake and PCNA, glut-1, and hexokinase-II expressions in cancers and inflammatory lesions of the lung. Neoplasia. 2005; 7: 369-79.
    • (2005) Neoplasia , vol.7 , pp. 369-379
    • Mamede, M.1    Higashi, T.2    Kitaichi, M.3
  • 17
    • 3242729483 scopus 로고    scopus 로고
    • Proinflammatory interleukin-1 cytokines increase mesangial cell hexokinase activity and hexokinase II isoform abundance
    • Taneja N, Coy PE, Lee I, et al. Proinflammatory interleukin-1 cytokines increase mesangial cell hexokinase activity and hexokinase II isoform abundance. Am J Physiol Cell Physiol. 2004; 287: C548-57.
    • (2004) Am J Physiol Cell Physiol , vol.287
    • Taneja, N.1    Coy, P.E.2    Lee, I.3
  • 18
    • 0742289564 scopus 로고    scopus 로고
    • Facilitative glucose transporter gene expression in human lymphocytes, monocytes, and macrophages: a role for GLUT isoforms 1, 3, and 5 in the immune response and foam cell formation
    • Fu Y, Maianu L, Melbert BR, Garvey WT. Facilitative glucose transporter gene expression in human lymphocytes, monocytes, and macrophages: a role for GLUT isoforms 1, 3, and 5 in the immune response and foam cell formation. Blood Cells Mol Dis. 2004; 32: 182-90.
    • (2004) Blood Cells Mol Dis , vol.32 , pp. 182-190
    • Fu, Y.1    Maianu, L.2    Melbert, B.R.3    Garvey, W.T.4
  • 19
    • 2342575613 scopus 로고    scopus 로고
    • Characterization of 18F-FDG uptake in human endothelial cells in vitro
    • Maschauer S, Prante O, Hoffmann M, et al. Characterization of 18F-FDG uptake in human endothelial cells in vitro. J Nucl Med. 2004; 45: 455-60.
    • (2004) J Nucl Med , vol.45 , pp. 455-460
    • Maschauer, S.1    Prante, O.2    Hoffmann, M.3
  • 20
    • 0026770922 scopus 로고
    • Serum glucose: effects on tumor and normal tissue accumulation of 2-[F-18]-fluoro-2-deoxy-D-glucose in rodents with mammary carcinoma
    • Wahl RL, Henry CA, Ethier SP. Serum glucose: effects on tumor and normal tissue accumulation of 2-[F-18]-fluoro-2-deoxy-D-glucose in rodents with mammary carcinoma. Radiology. 1992; 183: 643-7.
    • (1992) Radiology , vol.183 , pp. 643-647
    • Wahl, R.L.1    Henry, C.A.2    Ethier, S.P.3
  • 21
    • 0037062656 scopus 로고    scopus 로고
    • Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography
    • Rudd JH, Warburton EA, Fryer TD, et al. Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography. Circulation. 2002; 105: 2708-11.
    • (2002) Circulation , vol.105 , pp. 2708-2711
    • Rudd, J.H.1    Warburton, E.A.2    Fryer, T.D.3
  • 22
    • 0026592806 scopus 로고
    • Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
    • Zhang SH, Reddick RL, Piedrahita JA, Maeda N. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science. 1992; 258: 468-71.
    • (1992) Science , vol.258 , pp. 468-471
    • Zhang, S.H.1    Reddick, R.L.2    Piedrahita, J.A.3    Maeda, N.4
  • 23
    • 0030698676 scopus 로고    scopus 로고
    • Atherosclerosis: Imaging techniques and the evolving role of nuclear medicine
    • Vallabhajosula S, Fuster V. Atherosclerosis: Imaging techniques and the evolving role of nuclear medicine. J Nucl Med. 1997; 38: 1788-96.
    • (1997) J Nucl Med , vol.38 , pp. 1788-1796
    • Vallabhajosula, S.1    Fuster, V.2
  • 24
    • 20344374958 scopus 로고    scopus 로고
    • Noninvasive in vivo measurement of vascular inflammation with F-18 fluorodeoxyglucose positron emission tomography
    • Tawakol A, Migrino RQ, Hoffmann U, et al. Noninvasive in vivo measurement of vascular inflammation with F-18 fluorodeoxyglucose positron emission tomography. J Nucl Cardiol. 2005; 12: 294-301.
    • (2005) J Nucl Cardiol , vol.12 , pp. 294-301
    • Tawakol, A.1    Migrino, R.Q.2    Hoffmann, U.3
  • 25
    • 42449099036 scopus 로고    scopus 로고
    • Noninvasive detection and localization of vulnerable plaque and arterial thrombosis with computed tomography angiography/positron emission tomography
    • Aziz K, Berger K, Claycombe K, et al. Noninvasive detection and localization of vulnerable plaque and arterial thrombosis with computed tomography angiography/positron emission tomography. Circulation. 2008; 117: 2061-70.
    • (2008) Circulation , vol.117 , pp. 2061-2070
    • Aziz, K.1    Berger, K.2    Claycombe, K.3
  • 26
    • 53749096140 scopus 로고    scopus 로고
    • Prolonged high-fat feeding enhances aortic 18F-FDG and 99mTc-annexin A5 uptake in apolipoprotein E-deficient and wild-type C57BL/6J mice
    • This experimental animal study indicates a correlation between hypercholesterolemia (cholesterol loading of ApoE-/- mice over time) and F-18-FDG accumulation in murine aortas
    • • Zhao Y, Kuge Y, Zhao S, et al. Prolonged high-fat feeding enhances aortic 18F-FDG and 99mTc-annexin A5 uptake in apolipoprotein E-deficient and wild-type C57BL/6J mice. J Nucl Med. 2008; 49: 1707-14. This experimental animal study indicates a correlation between hypercholesterolemia (cholesterol loading of ApoE-/- mice over time) and F-18-FDG accumulation in murine aortas.
    • (2008) J Nucl Med , vol.49 , pp. 1707-1714
    • Zhao, Y.1    Kuge, Y.2    Zhao, S.3
  • 27
    • 33845351241 scopus 로고    scopus 로고
    • Non-specific binding of [18F]FDG to calcifications in atherosclerotic plaques: experimental study of mouse and human arteries
    • Laitinen I, Marjamaki P, Haaparanta M, et al. Non-specific binding of [18F]FDG to calcifications in atherosclerotic plaques: experimental study of mouse and human arteries. Eur J Nucl Med Mol Imaging. 2006; 33: 1461-7.
    • (2006) Eur J Nucl Med Mol Imaging , vol.33 , pp. 1461-1467
    • Laitinen, I.1    Marjamaki, P.2    Haaparanta, M.3
  • 28
    • 34248140651 scopus 로고    scopus 로고
    • Imaging of vulnerable atherosclerotic plaques with FDG-microPET: no FDG accumulation
    • Laurberg JM, Olsen AK, Hansen SB, et al. Imaging of vulnerable atherosclerotic plaques with FDG-microPET: no FDG accumulation. Atherosclerosis. 2007; 192: 275-82.
    • (2007) Atherosclerosis , vol.192 , pp. 275-282
    • Laurberg, J.M.1    Olsen, A.K.2    Hansen, S.B.3
  • 29
    • 34547952656 scopus 로고    scopus 로고
    • Application of 18F-FDG PET for monitoring the therapeutic effect of antiinflammatory drugs on stabilization of vulnerable atherosclerotic plaques
    • Ogawa M, Magata Y, Kato T, et al. Application of 18F-FDG PET for monitoring the therapeutic effect of antiinflammatory drugs on stabilization of vulnerable atherosclerotic plaques. J Nucl Med. 2006; 47: 1845-50.
    • (2006) J Nucl Med , vol.47 , pp. 1845-1850
    • Ogawa, M.1    Magata, Y.2    Kato, T.3
  • 30
    • 67449094297 scopus 로고    scopus 로고
    • In vivo non-invasive serial monitoring of FDG-PET progression and regression in a rabbit model of atherosclerosis
    • Worthley SG, Zhang ZY, Machac J, et al. In vivo non-invasive serial monitoring of FDG-PET progression and regression in a rabbit model of atherosclerosis. Int J Cardiovasc Imaging. 2009; 25: 251-7.
    • (2009) Int J Cardiovasc Imaging , vol.25 , pp. 251-257
    • Worthley, S.G.1    Zhang, Z.Y.2    Machac, J.3
  • 31
    • 0035106073 scopus 로고    scopus 로고
    • F-18 FDG uptake in the large arteries: a new observation
    • Yun M, Yeh D, Araujo LI, et al. F-18 FDG uptake in the large arteries: a new observation. Clin Nucl Med. 2001; 26: 314-9.
    • (2001) Clin Nucl Med , vol.26 , pp. 314-319
    • Yun, M.1    Yeh, D.2    Araujo, L.I.3
  • 32
    • 33644668977 scopus 로고    scopus 로고
    • Identification of culprit lesions after transient ischemic attack by combined 18F fluorodeoxyglucose positron-emission tomography and high-resolution magnetic resonance imaging
    • Davies JR, Rudd JH, Fryer TD, et al. Identification of culprit lesions after transient ischemic attack by combined 18F fluorodeoxyglucose positron-emission tomography and high-resolution magnetic resonance imaging. Stroke. 2005; 36: 2642-7.
    • (2005) Stroke , vol.36 , pp. 2642-2647
    • Davies, J.R.1    Rudd, J.H.2    Fryer, T.D.3
  • 33
    • 33750445273 scopus 로고    scopus 로고
    • In vivo 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients
    • Tawakol A, Migrino RQ, Bashian GG, et al. In vivo 18F-fluorodeoxyglucose positron emission tomography imaging provides a noninvasive measure of carotid plaque inflammation in patients. J Am Coll Cardiol. 2006; 48: 1818-24.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1818-1824
    • Tawakol, A.1    Migrino, R.Q.2    Bashian, G.G.3
  • 34
    • 34548748759 scopus 로고    scopus 로고
    • The prevalence of inflammation in carotid atherosclerosis: analysis with fluorodeoxyglucose-positron emission tomography
    • The presence of atherosclerosis alone does not predict the inflammatory status. This clinical study evaluated the frequency of inflammatory activity in carotid artery plaques by F-18-FDG PET. Inflammation was visualized by FDG-PET imaging in approximately 30% of patients with documented carotid atherosclerosis
    • • Tahara N, Kai H, Nakaura H, et al. The prevalence of inflammation in carotid atherosclerosis: analysis with fluorodeoxyglucose-positron emission tomography. Eur Heart J. 2007; 28: 2243-8. The presence of atherosclerosis alone does not predict the inflammatory status. This clinical study evaluated the frequency of inflammatory activity in carotid artery plaques by F-18-FDG PET. Inflammation was visualized by FDG-PET imaging in approximately 30% of patients with documented carotid atherosclerosis.
    • (2007) Eur Heart J , vol.28 , pp. 2243-2248
    • Tahara, N.1    Kai, H.2    Nakaura, H.3
  • 35
    • 36049029727 scopus 로고    scopus 로고
    • Radionuclide techniques for identifying vulnerable plaque
    • Dunphy MP, Schoder H, Strauss HW. Radionuclide techniques for identifying vulnerable plaque. J Nucl Med. 2007; 48: 1753-5.
    • (2007) J Nucl Med , vol.48 , pp. 1753-1755
    • Dunphy, M.P.1    Schoder, H.2    Strauss, H.W.3
  • 36
    • 70349643061 scopus 로고    scopus 로고
    • Relationships among regional arterial inflammation, calcification, risk factors, and biomarkers: a prospective fluorodeoxyglucose positron-emission tomography/computed tomography imaging study
    • This clinical study evaluated correlations between atherosclerotic plaque inflammation assessed by FDG PET and plaque calcification, serum biomarkers, and vascular risk factors. The authors suggest that FDG PET imaging could be used as a surrogate marker of atherosclerotic disease activity and for clinical risk prediction
    • •• Rudd JH, Myers KS, Bansilal S, et al. Relationships among regional arterial inflammation, calcification, risk factors, and biomarkers: a prospective fluorodeoxyglucose positron-emission tomography/computed tomography imaging study. Circ Cardiovasc Imaging. 2009; 2: 107-15. This clinical study evaluated correlations between atherosclerotic plaque inflammation assessed by FDG PET and plaque calcification, serum biomarkers, and vascular risk factors. The authors suggest that FDG PET imaging could be used as a surrogate marker of atherosclerotic disease activity and for clinical risk prediction.
    • (2009) Circ Cardiovasc Imaging , vol.2 , pp. 107-115
    • Rudd, J.H.1    Myers, K.S.2    Bansilal, S.3
  • 37
    • 33646396223 scopus 로고    scopus 로고
    • 18F-FDG accumulation in atherosclerosis: use of CT and MR co-registration of thoracic and carotid arteries
    • Okane K, Ibaraki M, Toyoshima H, et al. 18F-FDG accumulation in atherosclerosis: use of CT and MR co-registration of thoracic and carotid arteries. Eur J Nucl Med Mol Imaging. 2006; 33: 589-94.
    • (2006) Eur J Nucl Med Mol Imaging , vol.33 , pp. 589-594
    • Okane, K.1    Ibaraki, M.2    Toyoshima, H.3
  • 38
    • 34547954508 scopus 로고    scopus 로고
    • (18)fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible: implications for atherosclerosis therapy trials
    • This study evaluated the reproducibility of FDG PET findings by serial PET measurements. Spontaneous change in plaque FDG uptake was low over 2 weeks, with favorable interobserver and intraobserver agreement
    • •• Rudd JH, Myers KS, Bansilal S, et al. (18)fluorodeoxyglucose positron emission tomography imaging of atherosclerotic plaque inflammation is highly reproducible: implications for atherosclerosis therapy trials. J Am Coll Cardiol. 2007; 50: 892-6. This study evaluated the reproducibility of FDG PET findings by serial PET measurements. Spontaneous change in plaque FDG uptake was low over 2 weeks, with favorable interobserver and intraobserver agreement.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 892-896
    • Rudd, J.H.1    Myers, K.S.2    Bansilal, S.3
  • 39
    • 67349252062 scopus 로고    scopus 로고
    • Molecular pathology in vulnerable carotid plaques: correlation with [18]-fluorodeoxyglucose positron emission tomography (FDG-PET)
    • Graebe M, Pedersen SF, Borgwardt L, et al. Molecular pathology in vulnerable carotid plaques: correlation with [18]-fluorodeoxyglucose positron emission tomography (FDG-PET). Eur J Vasc Endovasc Surg. 2009; 37: 714-21.
    • (2009) Eur J Vasc Endovasc Surg , vol.37 , pp. 714-721
    • Graebe, M.1    Pedersen, S.F.2    Borgwardt, L.3
  • 40
    • 77951079412 scopus 로고    scopus 로고
    • Gene expression and 18FDG uptake in atherosclerotic carotid plaques
    • Pedersen SF, Graebe M, Fisker Hag AM, et al. Gene expression and 18FDG uptake in atherosclerotic carotid plaques. Nucl Med Commun. 2010; 31: 423-9.
    • (2010) Nucl Med Commun , vol.31 , pp. 423-429
    • Pedersen, S.F.1    Graebe, M.2    Fisker Hag, A.M.3
  • 41
    • 0345015524 scopus 로고    scopus 로고
    • Fluorodeoxyglucose uptake in the aortic wall at PET/CT: possible finding for active atherosclerosis
    • Tatsumi M, Cohade C, Nakamoto Y, Wahl RL. Fluorodeoxyglucose uptake in the aortic wall at PET/CT: possible finding for active atherosclerosis. Radiology. 2003; 229: 831-7.
    • (2003) Radiology , vol.229 , pp. 831-837
    • Tatsumi, M.1    Cohade, C.2    Nakamoto, Y.3    Wahl, R.L.4
  • 42
    • 0036007345 scopus 로고    scopus 로고
    • 18F FDG uptake in the large arteries: a correlation study with the atherogenic risk factors
    • Yun M, Jang S, Cucchiara A, et al. 18F FDG uptake in the large arteries: a correlation study with the atherogenic risk factors. Semin Nucl Med. 2002; 32: 70-6.
    • (2002) Semin Nucl Med , vol.32 , pp. 70-76
    • Yun, M.1    Jang, S.2    Cucchiara, A.3
  • 43
    • 34047179905 scopus 로고    scopus 로고
    • Vascular inflammation evaluated by [18F]-fluorodeoxyglucose positron emission tomography is associated with the metabolic syndrome
    • Tahara N, Kai H, Yamagishi S, et al. Vascular inflammation evaluated by [18F]-fluorodeoxyglucose positron emission tomography is associated with the metabolic syndrome. J Am Coll Cardiol. 2007; 49: 1533-9.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 1533-1539
    • Tahara, N.1    Kai, H.2    Yamagishi, S.3
  • 44
    • 34047221228 scopus 로고    scopus 로고
    • Characterization of plaques using 18F-FDG PET/CT in patients with carotid atherosclerosis and correlation with matrix metalloproteinase-1
    • This study indicated a link between 18-F-FDG uptake and levels of circulating MMP-1. The authors suppose that 18-F-FDG PET/CT could be used as an adjunct to the clinical management of high-risk atherosclerosis and an in vivo tool to study plaque biology
    • • Wu YW, Kao HL, Chen MF, et al. Characterization of plaques using 18F-FDG PET/CT in patients with carotid atherosclerosis and correlation with matrix metalloproteinase-1. J Nucl Med. 2007; 48: 227-33. This study indicated a link between 18-F-FDG uptake and levels of circulating MMP-1. The authors suppose that 18-F-FDG PET/CT could be used as an adjunct to the clinical management of high-risk atherosclerosis and an in vivo tool to study plaque biology.
    • (2007) J Nucl Med , vol.48 , pp. 227-233
    • Wu, Y.W.1    Kao, H.L.2    Chen, M.F.3
  • 45
    • 0037155057 scopus 로고    scopus 로고
    • Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly
    • Galis ZS, Khatri JJ. Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly. Circ Res. 2002; 90: 251-62.
    • (2002) Circ Res , vol.90 , pp. 251-262
    • Galis, Z.S.1    Khatri, J.J.2
  • 46
    • 2642575025 scopus 로고    scopus 로고
    • Scintigraphic imaging of matrix metalloproteinase activity in the arterial wall in vivo
    • Schäfers M, Riemann B, Kopka K, et al. Scintigraphic imaging of matrix metalloproteinase activity in the arterial wall in vivo. Circulation. 2004; 109: 2554-9.
    • (2004) Circulation , vol.109 , pp. 2554-2559
    • Schäfers, M.1    Riemann, B.2    Kopka, K.3
  • 47
    • 60149095901 scopus 로고    scopus 로고
    • A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: radiosynthesis and initial small-animal PET studies
    • Wagner S, Breyholz HJ, Höltke C, et al. A new 18F-labelled derivative of the MMP inhibitor CGS 27023A for PET: radiosynthesis and initial small-animal PET studies. Appl Radiat Isot. 2009; 67: 606-10.
    • (2009) Appl Radiat Isot , vol.67 , pp. 606-610
    • Wagner, S.1    Breyholz, H.J.2    Höltke, C.3
  • 48
    • 63149176591 scopus 로고    scopus 로고
    • Retrospective study of coronary uptake of 18F-fluorodeoxyglucose in association with calcification and coronary artery disease: a preliminary study
    • Williams G, Kolodny GM. Retrospective study of coronary uptake of 18F-fluorodeoxyglucose in association with calcification and coronary artery disease: a preliminary study. Nucl Med Commun. 2009; 30: 287-91.
    • (2009) Nucl Med Commun , vol.30 , pp. 287-291
    • Williams, G.1    Kolodny, G.M.2
  • 49
    • 40849136226 scopus 로고    scopus 로고
    • Arterial wall uptake of fluorodeoxyglucose on PET imaging in stable cancer disease patients indicates higher risk for cardiovascular events
    • This clinical study showed a correlation between the extent of arterial 18-FDG uptake and the occurrence of recent cardiovascular events, a hint toward a possible prognostic value of 18-F-FDG PET imaging
    • • Paulmier B, Duet M, Khayat R, et al. Arterial wall uptake of fluorodeoxyglucose on PET imaging in stable cancer disease patients indicates higher risk for cardiovascular events. J Nucl Cardiol. 2008; 15: 209-17. This clinical study showed a correlation between the extent of arterial 18-FDG uptake and the occurrence of recent cardiovascular events, a hint toward a possible prognostic value of 18-F-FDG PET imaging.
    • (2008) J Nucl Cardiol , vol.15 , pp. 209-217
    • Paulmier, B.1    Duet, M.2    Khayat, R.3
  • 50
    • 70349637021 scopus 로고    scopus 로고
    • 18F-FDG PET/CT identifies patients at risk for future vascular events in an otherwise asymptomatic cohort with neoplastic disease
    • Rominger A, Saam T, Wolpers S, et al. 18F-FDG PET/CT identifies patients at risk for future vascular events in an otherwise asymptomatic cohort with neoplastic disease. J Nucl Med. 2009; 50: 1611-20.
    • (2009) J Nucl Med , vol.50 , pp. 1611-1620
    • Rominger, A.1    Saam, T.2    Wolpers, S.3
  • 51
    • 77953141283 scopus 로고    scopus 로고
    • High-risk plaque initiative. The BIOIMAGE study: novel approaches to risk assessment in the primary prevention of atherosclerotic cardiovascular disease--study design and objectives
    • Muntendam P, McCall C, Sanz J, et al. High-risk plaque initiative. The BIOIMAGE study: novel approaches to risk assessment in the primary prevention of atherosclerotic cardiovascular disease--study design and objectives. Am Heart J. 2010; 160: 49-57. e1.
    • (2010) Am Heart J , vol.160 , pp. 49-57
    • Muntendam, P.1    McCall, C.2    Sanz, J.3
  • 52
    • 33750448287 scopus 로고    scopus 로고
    • Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography
    • Tahara N, Kai H, Ishibashi M, et al. Simvastatin attenuates plaque inflammation: evaluation by fluorodeoxyglucose positron emission tomography. J Am Coll Cardiol. 2006; 48: 1825-31.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 1825-1831
    • Tahara, N.1    Kai, H.2    Ishibashi, M.3
  • 53
    • 48749119873 scopus 로고    scopus 로고
    • Reversal of vascular 18F-FDG uptake with plasma high-density lipoprotein elevation by atherogenic risk reduction
    • This clinical study indicated that 18-F-FDG uptake is correlated to hypercholesterolemia in patients. Moreover, pre-existing vascular 18-F-FDG uptake was reduced over time in correlation to increases in plasma HDL levels achieved by lifestyle intervention. Thus, the authors suppose, serial 18-F-FDG PET/CT may be useful for monitoring improvements in the inflammatory component of atherosclerotic lesions in response to risk modification
    • • Lee SJ, On YK, Lee EJ, et al. Reversal of vascular 18F-FDG uptake with plasma high-density lipoprotein elevation by atherogenic risk reduction. J Nucl Med. 2008; 49: 1277-82. This clinical study indicated that 18-F-FDG uptake is correlated to hypercholesterolemia in patients. Moreover, pre-existing vascular 18-F-FDG uptake was reduced over time in correlation to increases in plasma HDL levels achieved by lifestyle intervention. Thus, the authors suppose, serial 18-F-FDG PET/CT may be useful for monitoring improvements in the inflammatory component of atherosclerotic lesions in response to risk modification.
    • (2008) J Nucl Med , vol.49 , pp. 1277-1282
    • Lee, S.J.1    On, Y.K.2    Lee, E.J.3
  • 54
    • 70350561707 scopus 로고    scopus 로고
    • Evaluation and comparison of 11C-choline uptake and calcification in aortic and common carotid arterial walls with combined PET/CT
    • Kato K, Schober O, Ikeda M, et al. Evaluation and comparison of 11C-choline uptake and calcification in aortic and common carotid arterial walls with combined PET/CT. Eur J Nucl Med Mol Imaging. 2009; 36: 1622-8.
    • (2009) Eur J Nucl Med Mol Imaging , vol.36 , pp. 1622-1628
    • Kato, K.1    Schober, O.2    Ikeda, M.3
  • 55
    • 77952308154 scopus 로고    scopus 로고
    • Uptake of 11C-choline in mouse atherosclerotic plaques
    • Laitinen IE, Luoto P, Nagren K, et al. Uptake of 11C-choline in mouse atherosclerotic plaques. J Nucl Med. 2010; 51: 798-802.
    • (2010) J Nucl Med , vol.51 , pp. 798-802
    • Laitinen, I.E.1    Luoto, P.2    Nagren, K.3
  • 56
    • 77956992860 scopus 로고    scopus 로고
    • 18F-fluoroethylcholine uptake in arterial vessel walls and cardiovascular risk factors: correlation in a PET-CT study
    • Forster S, Rominger A, Saam T, et al. 18F-fluoroethylcholine uptake in arterial vessel walls and cardiovascular risk factors: correlation in a PET-CT study. Nuklearmedizin. 2010; 49: 148-53.
    • (2010) Nuklearmedizin , vol.49 , pp. 148-153
    • Forster, S.1    Rominger, A.2    Saam, T.3
  • 57
    • 25444449786 scopus 로고    scopus 로고
    • Association of vascular 18F-FDG uptake with vascular calcification
    • Dunphy MP, Freiman A, Larson SM, Strauss HW. Association of vascular 18F-FDG uptake with vascular calcification. J Nucl Med. 2005; 46: 1278-84.
    • (2005) J Nucl Med , vol.46 , pp. 1278-1284
    • Dunphy, M.P.1    Freiman, A.2    Larson, S.M.3    Strauss, H.W.4
  • 58
    • 63849216723 scopus 로고    scopus 로고
    • Imaging of inflamed and vulnerable plaque in coronary arteries with 18F-FDG PET/CT in patients with suppression of myocardial uptake using a low-carbohydrate, high-fat preparation
    • Wykrzykowska J, Lehman S, Williams G, et al. Imaging of inflamed and vulnerable plaque in coronary arteries with 18F-FDG PET/CT in patients with suppression of myocardial uptake using a low-carbohydrate, high-fat preparation. J Nucl Med. 2009; 50: 563-8.
    • (2009) J Nucl Med , vol.50 , pp. 563-568
    • Wykrzykowska, J.1    Lehman, S.2    Williams, G.3
  • 59
    • 77952686489 scopus 로고    scopus 로고
    • Feasibility of FDG imaging of the coronary arteries: comparison between acute coronary syndrome and stable angina
    • Rogers IS, Nasir K, Figueroa AL, et al. Feasibility of FDG imaging of the coronary arteries: comparison between acute coronary syndrome and stable angina. JACC Cardiovasc Imaging. 2010; 3: 388-97.
    • (2010) JACC Cardiovasc Imaging , vol.3 , pp. 388-397
    • Rogers, I.S.1    Nasir, K.2    Figueroa, A.L.3
  • 60
    • 66149091184 scopus 로고    scopus 로고
    • List mode-driven cardiac and respiratory gating in PET
    • Buther F, Dawood M, Stegger L, et al. List mode-driven cardiac and respiratory gating in PET. J Nucl Med. 2009; 50: 674-81.
    • (2009) J Nucl Med , vol.50 , pp. 674-681
    • Buther, F.1    Dawood, M.2    Stegger, L.3
  • 61
    • 34548156510 scopus 로고    scopus 로고
    • Dual cardiac-respiratory gated PET: implementation and results from a feasibility study
    • Martinez-Moller A, Zikic D, Botnar RM, et al. Dual cardiac-respiratory gated PET: implementation and results from a feasibility study. Eur J Nucl Med Mol Imaging. 2007; 34: 1447-54.
    • (2007) Eur J Nucl Med Mol Imaging , vol.34 , pp. 1447-1454
    • Martinez-Moller, A.1    Zikic, D.2    Botnar, R.M.3
  • 62
    • 59149090701 scopus 로고    scopus 로고
    • Assessment of inactive, active and mixed atherosclerotic plaques by 18F-FDG-PET; an age group-based correlation with cardiovascular risk factors
    • Wasselius J, Larsson S, Sundin A, Jacobsson H. Assessment of inactive, active and mixed atherosclerotic plaques by 18F-FDG-PET; an age group-based correlation with cardiovascular risk factors. Int J Cardiovasc Imaging. 2009; 25: 133-40.
    • (2009) Int J Cardiovasc Imaging , vol.25 , pp. 133-140
    • Wasselius, J.1    Larsson, S.2    Sundin, A.3    Jacobsson, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.