Combined two-photon laser-scanning microscopy and spectral microCT X-ray imaging to characterize the cellular signature and evolution of microstroke foci

Romanian Journal of Morphology and Embryology

Volumn 53, Issue 3 SUPPL., 2012, Pages 671-675

  Kirchhoff, F ^a   Debarbieux, F ^b   Kronland Martinet, Carine ^b   Cojocaru, G R ^c   Popa Wagner, A ^c,d  

^a SAARLAND UNIVERSITY   (Germany)

^b AIX MARSEILLE UNIVERSITY   (France)

^c UNIVERSITY OF MEDICINE AND PHARMACY OF CRAIOVA   (Romania)

^d University Medicine Rostock   (Germany)

Author keywords

2P microscopy; Aging; Imaging; Microct; Stroke

Indexed keywords

ANIMAL; BRAIN ISCHEMIA; CEREBROVASCULAR ACCIDENT; CONFOCAL MICROSCOPY; HUMAN; IMAGE PROCESSING; METHODOLOGY; PATHOLOGY; RADIOGRAPHY; REVIEW;

ANIMALS; BRAIN ISCHEMIA; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; MICROSCOPY, CONFOCAL; STROKE;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 84870343124     PISSN: 12200522     EISSN: 20668279     Source Type: Journal    
DOI: None     Document Type: Review

References (37)

1. Desmond DW, Moroney JT, Sano M, Stern Y, Incidence of dementia after ischemic stroke: results of a longitudinal study, Stroke, 2002, 33(9):2254-2260.
2. Grau-Olivares M, Arboix A, Mild cognitive impairment in stroke patients with ischemic cerebral small-vessel disease: a forerunner of vascular dementia? Expert Rev Neurother, 2009, 9(8):1201-1217.
3. Downes CE, Crack PJ, Neural injury following stroke: are Toll-like receptors the link between the immune system and the CNS? Br J Pharmacol, 2010, 160(8):1872-1888.
4. Ransohoff RM, Cardona AE, The myeloid cells of the central nervous system parenchyma, Nature, 2010, 468(7321): 253-262.
5. Becker KJ, Kalil AJ, Tanzi P, Zierath DK, Savos AV, Gee JM, Hadwin J, Carter KT, Shibata D, Cain KC, Autoimmune responses to the brain after stroke are associated with worse outcome, Stroke, 2011, 42(10):2763-2769.
6. Kim JV, Kang SS, Dustin ML, McGavern DB, Myelomono-cytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis, Nature, 2009, 457(7226):191-195.
7. Barnett HJ, Stroke prevention in the elderly, Clin Exp Hypertens, 2002, 24(7-8):563-571.
8. Popa-Wagner A, Schröder E, Walker LC, Kessler C, beta-Amyloid precursor protein and ss-amyloid peptide immuno-reactivity in the rat brain after middle cerebral artery occlusion: effect of age, Stroke, 1998, 29(10):2196-2202.
9. Badan I, Buchhold B, Hamm A, Gratz M, Walker LC, Platt D, Kessler C, Popa-Wagner A, Accelerated glial reactivity to stroke in aged rats correlates with reduced functional recovery, J Cereb Blood Flow Metab, 2003, 23(7):845-854.
10. Lindner MD, Gribkoff VK, Donlan NA, Jones TA, Long-lasting functional disabilities in middle-aged rats with small cerebral infarcts, J Neurosci, 2003, 23(34):10913-10922.
11. Markus TM, Tsai SY, Bollnow MR, Farrer RG, O'Brien TE, Kindler-Baumann DR, Rausch M, Rudin M, Wiessner C, Mir AK, Schwab ME, Kartje GL, Recovery and brain reorganization after stroke in adult and aged rats, Ann Neurol, 2005, 58(6):950-953.
12. Buchhold B, Mogoanta L, Suofu Y, Hamm A, Walker L, Kessler Ch, Popa-Wagner A, Environmental enrichment improves functional and neuropathological indices following stroke in young and aged rats, Restor Neurol Neurosci, 2007, 25(5-6):467-484.
13. Popa-Wagner A, Badan I, Walker L, Groppa S, Patrana N, Kessler C, Accelerated infarct development, cytogenesis and apoptosis following transient cerebral ischemia in aged rats, Acta Neuropathol, 2007, 113(3):277-293.
14. Popa-Wagner A, Stöcker K, Balseanu AT, Rogalewski A, Diederich K, Minnerup J, Margaritescu C, Schäbitz WR, Effects of granulocyte-colony stimulating factor after stroke in aged rats, Stroke, 2010, 41(5):1027-1031.
15. Loubinoux I, Kronenberg G, Endres M, Schumann-Bard P, Freret T, Filipkowski RK, Kaczmarek L, Popa-Wagner A, Post-stroke depression: mechanisms, translation and therapy, J Cell Mol Med, 2012, 16(9):1961-1969.
16. Petzold GC, Murthy VN, Role of astrocytes in neurovascular coupling, Neuron, 2011, 71(5):782-797.
17. Dalkara T, Gursoy-Ozdemir Y, Yemisci M, Brain micro-vascular pericytes in health and disease, Acta Neuropathol, 2011, 122(1):1-9.
18. Beckmann N, Cannet C, Babin AL, Blé FX, Zurbruegg S, Kneuer R, Dousset V, In vivo visualization of macrophage infiltration and activity in inflammation using magnetic resonance imaging, Wiley Interdiscip Rev Nanomed Nano-biotechnol, 2009, 1(3):272-298.
19. Weise G, Basse-Lüsebrink TC, Kleinschnitz C, Kampf T, Jakob PM, Stoll G, In vivo imaging of stepwise vessel occlusion in cerebral photothrombosis of mice by 19F MRI, PLoS One, 2011, 6(12):e28143.
20. Hirrlinger J, Hülsmann S, Kirchhoff F, Astroglial processes show spontaneous motility at active synaptic terminals in situ, Eur J Neurosci, 2004, 20(8):2235-2239.
21. Nimmerjahn A, Kirchhoff F, Helmchen F, Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo, Science, 2005, 308(5726):1314-1318.
22. Dray C, Rougon G, Debarbieux F, Quantitative analysis by in vivo imaging of the dynamics of vascular and axonal networks in injured mouse spinal cord, Proc Natl Acad Sci U S A, 2009, 106(23):9459-9464.
23. Dibaj P, Nadrigny F, Steffens H, Scheller A, Hirrlinger J, Schomburg ED, Neusch C, Kirchhoff F, NO mediates micro-glial response to acute spinal cord injury under ATP control in vivo, Glia, 2010, 58(9):1133-1144.
24. Fenrich KK, Weber P, Hocine M, Zalc M, Rougon G, Debarbieux F, Long-term in vivo imaging of normal and pathological mouse spinal cord with subcellular resolution using implanted glass windows, J Physiol, 2012, 590(Pt 16): 3665-3675.
25. Sigler A, Murphy TH, In vivo 2-photon imaging of fine structure in the rodent brain: before, during, and after stroke, Stroke, 2010, 41(10 Suppl):S117-S123.
26. Masuda T, Croom D, Hida H, Kirov SA, Capillary blood flow around microglial somata determines dynamics of microglial processes in ischemic conditions, Glia, 2011, 59(11):1744-1753.
27. Hirrlinger PG, Scheller A, Braun C, Quintela-Schneider M, Fuss B, Hirrlinger J, Kirchhoff F, Expression of reef coral fluorescent proteins in the central nervous system of transgenic mice, Mol Cell Neurosci, 2005, 30(3):291-303.
28. Nolte C, Matyash M, Pivneva T, Schipke CG, Ohlemeyer C, Hanisch UK, Kirchhoff F, Kettenmann H, GFAP promoter-controlled EGFP-expressing transgenic mice: a tool to visualize astrocytes and astrogliosis in living brain tissue, Glia, 2001, 33(1):72-86.
29. Karram K, Goebbels S, Schwab M, Jennissen K, Seifert G, Steinhäuser C, Nave KA, Trotter J, NG2-expressing cells in the nervous system revealed by the NG2-EYFP-knockin mouse, Genesis, 2008, 46(12):743-757.
30. Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, Sher A, Littman DR, Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion, Mol Cell Biol, 2000, 20(11):4106-4114.
31. Kiessling F, Greschus S, Lichy MP, Bock M, Fink C, Vosseler S, Moll J, Mueller MM, Fusenig NE, Traupe H, Semmler W, Volumetric computed tomography (VCT): a new technology for noninvasive, high-resolution monitoring of tumor angiogenesis, Nat Med, 2004, 10(10):1133-1138.
32. Delpierre P, Debarbieux F, Basolo S, Berar JF, Bonissent A, Boudet N, Breugnon P, Caillot B, Cassol Brunner F, Chantepie B, Clemens JC, Dinkespiler B, Khouri R, Koudobine I, Mararazzo V, Meessen C, Menouni M, Morel C, Mouget C, Pangaud P, Peyrin F, Rougon G, Sappey-Marinier D, Valton S, Vigeolas E, PIXSCAN: Pixel detector CT-scanner for small animal imaging, Nucl Instr Meth Phys Res A, 2007, 571(1-2):425-428.
33. Cassol Brunner F, Dupont M, Meessen C, Boursier Y, Ouamara H, Bonissent A, Kronland-Martinet C, Clemens JC, Debarbieux F, Morel C, First K-edge imaging with a micro-CT based on the XPAD3 hybrid pixel detector, IEEE Trans Nucl Sci, 2012, in press.
34. Debarbieux F, Bonissent A, Breugnon P, Cassol Brunner F, Delpierre PA, Hemmer C, Clemens JC, Dinkespiler B, Luchino J, Mann F, Meessen C, Vigeolas E, Rougon G, Morel C, Repeated imaging of lung cancer development using PIXSCAN, a low dose micro-CT scanner based on XPAD hybrid pixel detectors, IEEE Trans Nucl Sci, 2010, 57(1):242-245.
35. Schlomka JP, Roessl E, Dorscheid R, Dill S, Martens G, Istel T, Bäumer C, Herrmann C, Steadman R, Zeitler G, Livne A, Proksa R, Experimental feasibility of multi-energy photon-counting K-edge imaging in pre-clinical computed tomography, Phys Med Biol, 2008, 53:4031-4047.
36. Ritman EL, Molecular imaging in small animals-roles for micro-CT, J Cell Biochem Suppl, 2002, 39:116-124.
37. Hyafil F, Cornily JC, Rudd JH, Machac J, Feldman LJ, Fayad ZA, Quantification of inflammation within rabbit atherosclerotic plaques using the macrophage-specific CT contrast agent N1177: a comparison with 18F-FDG PET/CT and histology, J Nucl Med, 2009, 50(6):959-965.