MR chemical exchange imaging with spin-lock technique (CESL): A theoretical analysis of the Z-spectrum using a two-pool R1 relaxation model beyond the fast-exchange limit

Physics in Medicine and Biology

Volumn 57, Issue 24, 2012, Pages 8185-8200

  Yuan, Jing ^a   Zhou, Jinyuan ^b,c   Ahuja, Anil T ^a   Wang, Yi Xiang J ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c KENNEDY KRIEGER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL EXCHANGE; CHEMICAL EXCHANGE SATURATION TRANSFER; CONTRAST ENHANCEMENT; CONTRAST MECHANISM; FAST PROTONS; MAGNETIZATION TRANSFER RATIO; PHYSIOLOGICAL PROPERTIES; PULSE PARAMETER; RELAXATION MODELS; SPINLOCK; STATIC MAGNETIC FIELDS;

COMPUTER SIMULATION; LAKES; PHYSIOLOGICAL MODELS;

CHEMICAL ANALYSIS;

ARTICLE; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; SPECTROSCOPY; THEORETICAL MODEL; TIME;

MAGNETIC RESONANCE IMAGING; MODELS, THEORETICAL; SPECTRUM ANALYSIS; TIME FACTORS;

EID: 84870322280     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/57/24/8185     Document Type: Article

References (40)

1. Borthakur A, Sochor M, Davatzikos C, Trojanowski J Q and Clark C M 2008 T1rho MRI of Alzheimer's disease Neuroimage 41 1199-205
2. Cai K, Haris M, Singh A, Kogan F, Greenberg J H, Hariharan H, Detre J A and Reddy R 2012 Magnetic resonance imaging of glutamate Nat. Med. 18 302-6
3. Charagundla S R, Borthakur A, Leigh J S and Reddy R 2003 Artifacts in T(1rho)-weighted imaging: correction with a self-compensating spin-locking pulse J. Magn. Reson. 162 113-21
4. Chen W, Takahashi A and Han E 2011 Quantitative T(1)(rho) imaging using phase cycling for B(0) and B(1) field inhomogeneity compensation Magn. Reson. Imaging 29 608-19
5. Davis D G and Bax A 1985 Separation of chemical exchange and cross-relaxation effects in two-dimensional NMR-spectroscopy J. Magn. Reson. 64 533-5
6. Desvaux H and Berthault P 1999 Study of dynamic processes in liquids using off-resonance RF irradiation Prog. Nucl. Magn. Reson. Spectrosc. 35 295-340 (Pubitemid 129593318)
7. Dixon W T, Ren J, Lubag A J, Ratnakar J, Vinogradov E, Hancu I, Lenkinski R E and Sherry A D 2010 A concentration-independent method to measure exchange rates in PARACEST agents Magn. Reson. Med. 63 625-32
8. Duvvuri U, Goldberg A D, Kranz J K, Hoang L, Reddy R, Wehrli F W, Wand A J, Englander S W and Leigh J S 2001 Water magnetic relaxation dispersion in biological systems: the contribution of proton exchange and implications for the noninvasive detection of cartilage degradation Proc. Natl Acad. Sci. USA 98 12479-84 (Pubitemid 33019971)
9. Jin T, Autio J, Obata T and Kim S G 2011 Spin-locking versus chemical exchange saturation transfer MRI for investigating chemical exchange process between water and labile metabolite protons Magn. Reson. Med. 65 1448-60
10. Jin T, Wang P, Zong X and Kim S G 2012 Magnetic resonance imaging of the amine-proton exchange (APEX) dependent contrast Neuroimage 59 1218-27
11. Johannessen W, Auerbach J D, Wheaton A J, Kurji A, Borthakur A, Reddy R and Elliott D M 2006 Assessment of human disc degeneration and proteoglycan content using T1rho-weighted magnetic resonance imaging Spine (Phila Pa 1976) 31 1253-7
12. Kim M, Gillen J, Landman B A, Zhou J and van Zijl P C 2009 Water saturation shift referencing (WASSR) for chemical exchange saturation transfer (CEST) experiments Magn. Reson. Med. 61 1441-50
13. Kogan F, Singh A, Cai K, Haris M, Hariharan H and Reddy R 2012 Investigation of chemical exchange at intermediate exchange rates using a combination of chemical exchange saturation transfer (CEST) and spin-locking methods (CESTrho) Magn. Reson. Med. 68 107-19
14. Li X, Han E T, Busse R F and Majumdar S 2008 In vivo T(1rho) mapping in cartilage using 3D magnetization-prepared angle-modulated partitioned k-space spoiled gradient echo snapshots (3D MAPSS) Magn. Reson. Med. 59 298-307 (Pubitemid 351220093)
15. Ling W, Regatte R R, Navon G and Jerschow A 2008 Assessment of glycosaminoglycan concentration in vivo by chemical exchange-dependent saturation transfer (gagCEST) Proc. Natl Acad. Sci. USA 105 2266-70 (Pubitemid 351520501)
16. McMahon M T, Gilad A A, Zhou J, Sun P Z, Bulte J W and van Zijl P C 2006 Quantifying exchange rates in chemical exchange saturation transfer agents using the saturation time and saturation power dependencies of the magnetization transfer effect on the magnetic resonance imaging signal (QUEST and QUESP): Ph calibration for poly-L-lysine and a starburst dendrimer Magn. Reson. Med. 55 836-47
17. Scheidegger R, Vinogradov E and Alsop D C 2011 Amide proton transfer imaging with improved robustness to magnetic field inhomogeneity and magnetization transfer asymmetry using saturation with frequency alternating RF irradiation Magn. Reson. Med. 66 1275-85
18. Sherry A D and Woods M 2008 Chemical exchange saturation transfer contrast agents for magnetic resonance imaging Annu. Rev. Biomed. Eng. 10 391-411
19. Stanisz G J, Odrobina E E, Pun J, Escaravage M, Graham S J, Bronskill M J and Henkelman R M 2005 T1, T2 relaxation and magnetization transfer in tissue at 3T Magn. Reson. Med. 54 507-12 (Pubitemid 41233744)
20. Sun P Z 2010 Simultaneous determination of labile proton concentration and exchange rate utilizing optimal RF power: Radio frequency power (RFP) dependence of chemical exchange saturation transfer (CEST) MRI J. Magn. Reson. 202 155-61
21. Sun P Z, Farrar C T and Sorensen A G 2007a Correction for artifacts induced by B(0) and B(1) field inhomogeneities in pH-sensitive chemical exchange saturation transfer (CEST) imaging Magn. Reson. Med. 58 1207-15 (Pubitemid 350234207)
22. Sun P Z, van Zijl P C and Zhou J 2005 Optimization of the irradiation power in chemical exchange dependent saturation transfer experiments J. Magn. Reson. 175 193-200 (Pubitemid 40891674)
23. Sun P Z, Zhou J, Huang J and van Zijl P 2007b Simplified quantitative description of amide proton transfer (APT) imaging during acute ischemia Magn. Reson. Med. 57 405-10 (Pubitemid 46214544)
24. Trott O and Palmer A G 3rd 2002 R1rho relaxation outside of the fast-exchange limit J. Magn. Reson. 154 157-60
25. van Zijl P C and Yadav N N 2011 Chemical exchange saturation transfer (CEST): what is in a name and what isn't? Magn. Reson. Med. 65 927-48
26. Wang Y X, Yuan J, Chu E S, Go M Y, Huang H, Ahuja A T, Sung J J and Yu J 2011 T1rho MR imaging is sensitive to evaluate liver fibrosis: an experimental study in a rat biliary duct ligation model Radiology 259 712-9
27. Ward K M, Aletras A H and Balaban R S 2000 A new class of contrast agents for MRI based on proton chemical exchange dependent saturation transfer (CEST) J. Magn. Reson. 143 79-87
28. Ward K M and Balaban R S 2000 Determination of pH using water protons and chemical exchange dependent saturation transfer (CEST) Magn. Reson. Med. 44 799-802
29. Witschey W R 2nd, Borthakur A, Elliott M A, Mellon E, Niyogi S, Wallman D J, Wang C and Reddy R 2007 Artifacts in T1 rho-weighted imaging: compensation for B(1) and B(0) field imperfections J. Magn. Reson. 186 75-85 (Pubitemid 46635246)
30. Woessner D E, Zhang S, Merritt M E and Sherry A D 2005 Numerical solution of the Bloch equations provides insights into the optimum design of PARACEST agents for MRI Magn. Reson. Med. 53 790-9 (Pubitemid 40478426)
31. Yuan J, Li Y, Zhao F, Chan Q, Ahuja A T and Wang Y X 2012a Quantification of T1rho relaxation by using rotary echo spin-lock pulses in the presence of B0 inhomogeneity Phys. Med. Biol. 57 5003-16
32. Yuan J, Zhao F, Griffith J F, Chan Q and Wang Y X 2012b Optimized efficient liver T1rho mapping using limited spin lock times Phys. Med. Biol. 57 1631-40
33. Zaiss M and Bachert P 2012 Equivalence of spin-lock and magnetization transfer NMR experiments arXiv:1203.2067
34. Zaiss M, Schnurr M and Bachert P 2012 Analytical solution for the depolarization of hyperpolarized nuclei by chemical exchange saturation transfer between free and encapsulated xenon (HyperCEST) J. Chem. Phys. 136 144106
35. Zhang S, Malloy C R and Sherry A D 2005 MRI thermometry based on PARACEST agents J. Am. Chem. Soc. 127 17572-3 (Pubitemid 43003350)
36. Zhang S, Merritt M, Woessner D E, Lenkinski R E and Sherry A D 2003 PARACEST agents: modulating MRI contrast via water proton exchange Acc. Chem. Res. 36 783-90
37. Zhou J, Lal B, Wilson D A, Laterra J and van Zijl P C 2003a Amide proton transfer (APT) contrast for imaging of brain tumors Magn. Reson. Med. 50 1120-6 (Pubitemid 37494013)
38. Zhou J Y, Payen J F, Wilson D A, Traystman R J and van Zijl P C M 2003b Using the amide proton signals of intracellular proteins and peptides to detect pH effects in MRI Nat. Med. 9 1085-90 (Pubitemid 37021791)
39. Zhou J, Wilson D A, Sun P Z, Klaus J A and Van Zijl P C 2004 Quantitative description of proton exchange processes between water and endogenous and exogenous agents for WEX, CEST, and APT experiments Magn. Reson. Med. 51 945-52 (Pubitemid 38580606)
40. Zhou J et al 2011 Differentiation between glioma and radiation necrosis using molecular magnetic resonance imaging of endogenous proteins and peptides Nat. Med. 17 130-4