Remission induced by autologous hematopoietic stem cell transplantation in one newly diagnosed type 1 diabetes patient with diabetic ketoacidosis: A case report

Journal of Diabetes

Volumn 4, Issue 4, 2012, Pages 359-361

  Shen, Shanmei ^a   Li, Lirong ^a   Ouyang, Jian ^a   Xu, Jingyan ^a   Zhu, Dalong ^a  

^a THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

Author keywords

Asian Indians; Cardiovascular disease; Indian diabetes risk score; Menopause; Obesity

Indexed keywords

CYCLOPHOSPHAMIDE; GLUCOSE; GRANULOCYTE COLONY STIMULATING FACTOR; INSULIN; KETONE; THYMOCYTE ANTIBODY;

ADULT; ALOPECIA; ARTICLE; AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANTATION; CASE REPORT; CD34 SELECTION; COMA; CONTINUOUS INFUSION; DIABETIC KETOACIDOSIS; FEVER; FOLLOW UP; GLUCOSE BLOOD LEVEL; GLUCOSE URINE LEVEL; GLYCEMIC CONTROL; HOSPITAL ADMISSION; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; KETONURIA; LEUKOPENIA; MALE; NAUSEA AND VOMITING; POLYDIPSIA; POLYURIA; POSTPRANDIAL STATE; PRIORITY JOURNAL; REMISSION; UNCONSCIOUSNESS; WEIGHT REDUCTION;

ADULT; DIABETES MELLITUS, TYPE 1; DIABETIC KETOACIDOSIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; MALE; REMISSION INDUCTION;

EID: 84870314433     PISSN: 17530393     EISSN: 17530407     Source Type: Journal    
DOI: 10.1111/j.1753-0407.2012.00214.x     Document Type: Article

References (11)

1. LoCascio SA, Spinelli J, Kurtz J. Hematopoietic stem cell transplantation for the treatment of autoimmunity in type 1 diabetes. Curr Stem Cell Res Ther. 2011; 6: 29-37.
2. Milanetti F, Abinun M, Voltarelli JC, Burt RK. Autologous hematopoietic stem cell transplantation for childhood autoimmune disease. Pediatr Clin N Am. 2010; 57: 239-71.
3. Sia C, Homo-Delarche F. Tolerance induction and endogenous regeneration of pancreatic beta-cells in established autoimmune diabetes. Rev Diabet Stud. 2004; 1: 198-206.
4. Hasegawa Y, Ogihara T, Yamada T et al. Bone marrow (BM) transplantation promotes beta-cell regeneration after acute injury through BM cell mobilization. Endocrinology. 2007; 148: 2006-15.
5. Ablamunits V, Sherry NA, Kushner JA et al. Autoimmunity and beta cell reneneration in mouse and human type 1 diabetes: The peace is not enough. Ann N Y Acad Sci. 2007; 1103: 19-32.
6. Steffes MW, Sibley S, Jackson M et al. Beta-cell function and the development of diabetes-related complications in the Diabetes Control and Complications Trial. Diabetes Care. 2003; 26: 832-6.
7. The Diabetes Control and Complications Trial Research Group. Effect of intensive therapy on residual beta-cell function in patients with type 1 diabetes in the Diabetes Control and Complications Trial. Ann Intern Med. 1998; 128: 517-23.
8. Voharelli JC, Couri EB, Boris N et al. Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type l diabetes mellitus. JAMA. 2007; 297: 1568-77.
9. Couri CE, Oliveira MC, Stracieri AB et al.C-Peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus. JAMA. 2009; 301: 1573-9.
10. Asano M, Toda M, Sakaguchi N et al. Autoimmune disease as a consequence of developmental abnormality of a T cell subpopulation. J Exp Med. 1996; 184: 387-96.
11. + regulatory T cells. Blood. 2008; 111: 5233-41.