Plausible antioxidant biomechanics and anticonvulsant pharmacological activity of brain-targeted β-carotene nanoparticles

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 4311-4322

  Yusuf, Mohammad ^a   Khan, Riaz A ^b   Khan, Maria ^a   Ahmed, Bahar ^a  

^a HAMDARD UNIVERSITY   (India)

^b MANAV RACHNA INTERNATIONAL INSTITUTE OF RESEARCH AND STUDIES   (India)

Author keywords

Anticonvulsant; Blood brain barrier (BBB); Maximal electroshock seizure (MES); Pentylenetetrazole (PTZ); Polysorbate 80 coated carotene nanoparticles (P 80 BCNP); Targeted brain delivery

Indexed keywords

BETA CAROTENE; NANOPARTICLE; PLACEBO; POLYGLACTIN; POLYSORBATE 80;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DISEASE DURATION; DOSE RESPONSE; DRUG BIOAVAILABILITY; DRUG COATING; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG FORMULATION; DRUG MECHANISM; DRUG RECEPTOR BINDING; DRUG RELEASE; DRUG STABILITY; DRUG SYNTHESIS; DRUG TARGETING; IN VITRO STUDY; IN VIVO STUDY; LATENT PERIOD; LOW DRUG DOSE; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PHARMACOLOGICAL PARAMETERS; POLYDISPERSITY INDEX; TIME TO MAXIMUM PLASMA CONCENTRATION; TONIC CLONIC SEIZURE; ZETA POTENTIAL;

ANALYSIS OF VARIANCE; ANIMALS; ANTICONVULSANTS; ANTIOXIDANTS; BETA CAROTENE; BRAIN; CALORIMETRY, DIFFERENTIAL SCANNING; DISEASE MODELS, ANIMAL; ELECTROSHOCK; LACTIC ACID; MALE; MICE; NANOPARTICLES; OXIDATIVE STRESS; PARTICLE SIZE; PENTYLENETETRAZOLE; POLYGLYCOLIC ACID; POLYSORBATES; SEIZURES;

MUS;

EID: 84870310823     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S34588     Document Type: Article

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