-
1
-
-
74549140993
-
Prevalence and trends in obesity among US adults 1999-2008
-
Flegal KM, Carroll MD, Ogden CL, Curtin LR. Prevalence and trends in obesity among US adults, 1999-2008. JAMA 2010;303:235-241.
-
(2010)
JAMA
, vol.303
, pp. 235-241
-
-
Flegal, K.M.1
Carroll, M.D.2
Ogden, C.L.3
Curtin, L.R.4
-
2
-
-
33749616411
-
The medical complications of obesity
-
Malnick SD, Knobler H. The medical complications of obesity. QJM 2006;99:565-579.
-
(2006)
QJM
, vol.99
, pp. 565-579
-
-
Malnick, S.D.1
Knobler, H.2
-
3
-
-
35848935201
-
Cause-specific excess deaths associated with underweight, overweight, and obesity
-
Flegal KM, Graubard BI, Williamson DF, Gail MH. Cause-specific excess deaths associated with underweight, overweight, and obesity. JAMA 2007;298:2028-2037.
-
(2007)
JAMA
, vol.298
, pp. 2028-2037
-
-
Flegal, K.M.1
Graubard, B.I.2
Williamson, D.F.3
Gail, M.H.4
-
4
-
-
48749110626
-
The lifetime medical cost burden of overweight and obesity: Implications for obesity prevention
-
Finkelstein EA, Trogdon JG, Brown DS et al. The lifetime medical cost burden of overweight and obesity: implications for obesity prevention. Obesity (Silver Spring) 2008;16:1843-1848.
-
(2008)
Obesity (Silver Spring
, vol.16
, pp. 1843-1848
-
-
Finkelstein, E.A.1
Trogdon, J.G.2
Brown, D.S.3
-
5
-
-
0030843960
-
Genetic and environmental factors in relative body weight and human adiposity
-
Maes HH, Neale MC, Eaves LJ. Genetic and environmental factors in relative body weight and human adiposity. Behav Genet 1997;27:325-351.
-
(1997)
Behav Genet
, vol.27
, pp. 325-351
-
-
Maes, H.H.1
Neale, M.C.2
Eaves, L.J.3
-
6
-
-
0036844002
-
Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study
-
Atwood LD, Heard-Costa NL, Cupples LA et al. Genomewide linkage analysis of body mass index across 28 years of the Framingham Heart Study. Am J Hum Genet 2002;71:1044-1050.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 1044-1050
-
-
Atwood, L.D.1
Heard-Costa, N.L.2
Cupples, L.A.3
-
7
-
-
70349956433
-
Finding the missing heritability of complex diseases
-
Manolio TA, Collins FS, Cox NJ et al. Finding the missing heritability of complex diseases. Nature 2009;461:747-753.
-
(2009)
Nature
, vol.461
, pp. 747-753
-
-
Manolio, T.A.1
Collins, F.S.2
Cox, N.J.3
-
8
-
-
77952557918
-
Missing heritability and strategies for finding the underlying causes of complex disease
-
Eichler EE, Flint J, Gibson G et al. Missing heritability and strategies for finding the underlying causes of complex disease. Nat Rev Genet 2010;11:446-450.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 446-450
-
-
Eichler, E.E.1
Flint, J.2
Gibson, G.3
-
9
-
-
77954657070
-
Functional impact of global rare copy number variation in autism spectrum disorders
-
Pinto D, Pagnamenta AT, Klei L et al. Functional impact of global rare copy number variation in autism spectrum disorders. Nature 2010;466:368-372.
-
(2010)
Nature
, vol.466
, pp. 368-372
-
-
Pinto, D.1
Pagnamenta, A.T.2
Klei, L.3
-
10
-
-
70349756961
-
Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans
-
Xu B, Woodroffe A, Rodriguez-Murillo L et al. Elucidating the genetic architecture of familial schizophrenia using rare copy number variant and linkage scans. Proc Natl Acad Sci USA 2009;106:16746-16751.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 16746-16751
-
-
Xu, B.1
Woodroffe, A.2
Rodriguez-Murillo, L.3
-
11
-
-
77955029498
-
Copy number, linkage disequilibrium and disease association in the FCGR locus
-
Niederer HA, Willcocks LC, Rayner TF et al. Copy number, linkage disequilibrium and disease association in the FCGR locus. Hum Mol Genet 2010;19:3282-3294.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3282-3294
-
-
Niederer, H.A.1
Willcocks, L.C.2
Rayner, T.F.3
-
12
-
-
78649745154
-
Genome-wide analysis of copy number variation in type 1 diabetes
-
Grayson BL, Smith ME, Thomas JW et al. Genome-wide analysis of copy number variation in type 1 diabetes. PLoS ONE 2010;5:e15393.
-
(2010)
PLoS ONE
, vol.5
-
-
Grayson, B.L.1
Smith, M.E.2
Thomas, J.W.3
-
13
-
-
33846978695
-
Relative impact of nucleotide and copy number variation on gene expression phenotypes
-
Stranger BE, Forrest MS, Dunning M et al. Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science 2007;315:848-853.
-
(2007)
Science
, vol.315
, pp. 848-853
-
-
Stranger, B.E.1
Forrest, M.S.2
Dunning, M.3
-
14
-
-
77949899816
-
A common copy number variation on chromosome 6 association with the gene expression level of endothelin 1 in transformed B lymphocytes from three racial groups
-
Sun YV, Peyser PA, Kardia SL. A common copy number variation on chromosome 6 association with the gene expression level of endothelin 1 in transformed B lymphocytes from three racial groups. Circ Cardiovasc Genet 2009;2:483-488.
-
(2009)
Circ Cardiovasc Genet
, vol.2
, pp. 483-488
-
-
Sun, Y.V.1
Peyser, P.A.2
Kardia, S.L.3
-
15
-
-
77958495152
-
Identification of epistatic effects using a protein-protein interaction database
-
Sun YV, Kardia SL. Identification of epistatic effects using a protein-protein interaction database. Hum Mol Genet 2010;19:4345-4352.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 4345-4352
-
-
Sun, Y.V.1
Kardia, S.L.2
-
16
-
-
76349083132
-
Large, rare chromosomal deletions associated with severe early-onset obesity
-
Bochukova EG, Huang N, Keogh J et al. Large, rare chromosomal deletions associated with severe early-onset obesity. Nature 2010;463:666-670.
-
(2010)
Nature
, vol.463
, pp. 666-670
-
-
Bochukova, E.G.1
Huang, N.2
Keogh, J.3
-
17
-
-
77957606877
-
Large copy-number variations are enriched in cases with moderate to extreme obesity
-
Wang K, Li WD, Glessner JT et al. Large copy-number variations are enriched in cases with moderate to extreme obesity. Diabetes 2010;59:2690-2694.
-
(2010)
Diabetes
, vol.59
, pp. 2690-2694
-
-
Wang, K.1
Li, W.D.2
Glessner, J.T.3
-
18
-
-
77954168060
-
Genome-wide association of anthropometric traits in African-and African-derived populations
-
Kang SJ, Chiang CW, Palmer CD et al. Genome-wide association of anthropometric traits in African-and African-derived populations. Hum Mol Genet 2010;19:2725-2738.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 2725-2738
-
-
Kang, S.J.1
Chiang, C.W.2
Palmer, C.D.3
-
19
-
-
78249239776
-
A genome-wide study reveals copy number variants exclusive to childhood obesity cases
-
Glessner JT, Bradfield JP, Wang K et al. A genome-wide study reveals copy number variants exclusive to childhood obesity cases. Am J Hum Genet 2010;87:661-666.
-
(2010)
Am J Hum Genet
, vol.87
, pp. 661-666
-
-
Glessner, J.T.1
Bradfield, J.P.2
Wang, K.3
-
20
-
-
66249144682
-
Genome-wide association study suggested copy number variation may be associated with body mass index in the Chinese population
-
Sha BY, Yang TL, Zhao LJ et al. Genome-wide association study suggested copy number variation may be associated with body mass index in the Chinese population. J Hum Genet 2009;54:199-202.
-
(2009)
J Hum Genet
, vol.54
, pp. 199-202
-
-
Sha, B.Y.1
Yang, T.L.2
Zhao, L.J.3
-
21
-
-
78751700313
-
Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genomewide analysis
-
Jarick I, Vogel CI, Scherag S et al. Novel common copy number variation for early onset extreme obesity on chromosome 11q11 identified by a genomewide analysis. Hum Mol Genet 2011;20:840-852.
-
(2011)
Hum Mol Genet
, vol.20
, pp. 840-852
-
-
Jarick, I.1
Vogel, C.I.2
Scherag, S.3
-
22
-
-
58149163142
-
Six new loci associated with body mass index highlight a neuronal influence on body weight regulation
-
Wellcome Trust Case Control Consortium; Genetic Investigation of ANthropometric Traits Consortium
-
Willer CJ, Speliotes EK, Loos RJ et al.; Wellcome Trust Case Control Consortium; Genetic Investigation of ANthropometric Traits Consortium. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. Nat Genet 2009;41:25-34.
-
(2009)
Nat Genet
, vol.41
, pp. 25-34
-
-
Willer, C.J.1
Speliotes, E.K.2
Loos, R.J.3
-
23
-
-
78049337953
-
Association analyses of 249796 individuals reveal 18 new loci associated with body mass index
-
MAGIC; Procardis Consortium
-
Speliotes EK, Willer CJ, Berndt SI et al.; MAGIC; Procardis Consortium. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index. Nat Genet 2010;42:937-948.
-
(2010)
Nat Genet
, vol.42
, pp. 937-948
-
-
Speliotes, E.K.1
Willer, C.J.2
Berndt, S.I.3
-
24
-
-
2342627378
-
Genetic Epidemiology Network of Arteriopathy study. Familial aggregation of hypertension treatment and control in the Genetic Epidemiology Network of Arteriopathy (GENOA) study
-
Daniels PR, Kardia SL, Hanis CL et al.; Genetic Epidemiology Network of Arteriopathy study. Familial aggregation of hypertension treatment and control in the Genetic Epidemiology Network of Arteriopathy (GENOA) study. Am J Med 2004;116:676-681.
-
(2004)
Am J Med
, vol.116
, pp. 676-681
-
-
Daniels, P.R.1
Kardia, S.L.2
Hanis, C.L.3
-
25
-
-
0033846231
-
NHLBI family blood pressure program: Methodology and recruitment in the HyperGEN network Hypertension genetic epidemiology network
-
Williams RR, Rao DC, Ellison RC et al. NHLBI family blood pressure program: methodology and recruitment in the HyperGEN network. Hypertension genetic epidemiology network. Ann Epidemiol 2000;10: 389-400.
-
(2000)
Ann Epidemiol
, vol.10
, pp. 389-400
-
-
Williams, R.R.1
Rao, D.C.2
Ellison, R.C.3
-
26
-
-
52949085789
-
Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs
-
Korn JM, Kuruvilla FG, McCarroll SA et al. Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nat Genet 2008;40:1253-1260.
-
(2008)
Nat Genet
, vol.40
, pp. 1253-1260
-
-
Korn, J.M.1
Kuruvilla, F.G.2
McCarroll, S.A.3
-
27
-
-
52949085789
-
Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs
-
Korn JM, Kuruvilla FG, McCarroll SA et al. Integrated genotype calling and association analysis of SNPs, common copy number polymorphisms and rare CNVs. Nat Genet 2008;40:1253-1260.
-
(2008)
Nat Genet
, vol.40
, pp. 1253-1260
-
-
Korn, J.M.1
Kuruvilla, F.G.2
McCarroll, S.A.3
-
28
-
-
77956873627
-
Tackling the widespread and critical impact of batch effects in high-throughput data
-
Leek JT, Scharpf RB, Bravo HC et al. Tackling the widespread and critical impact of batch effects in high-throughput data. Nat Rev Genet 2010;11:733-739.
-
(2010)
Nat Rev Genet
, vol.11
, pp. 733-739
-
-
Leek, J.T.1
Scharpf, R.B.2
Bravo, H.C.3
-
29
-
-
33746512512
-
Principal components analysis corrects for stratification in genome-wide association studies
-
Price AL, Patterson NJ, Plenge RM et al. Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 2006;38:904-909.
-
(2006)
Nat Genet
, vol.38
, pp. 904-909
-
-
Price, A.L.1
Patterson, N.J.2
Plenge, R.M.3
-
30
-
-
77955894071
-
METAL: Fast and efficient meta-analysis of genomewide association scans
-
Willer CJ, Li Y, Abecasis GR. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics 2010;26:2190-2191.
-
(2010)
Bioinformatics
, vol.26
, pp. 2190-2191
-
-
Willer, C.J.1
Li, Y.2
Abecasis, G.R.3
-
31
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998;392: 605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
-
32
-
-
10744221310
-
Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse
-
Itier JM, Ibanez P, Mena MA et al. Parkin gene inactivation alters behaviour and dopamine neurotransmission in the mouse. Hum Mol Genet 2003;12:2277-2291.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2277-2291
-
-
Itier, J.M.1
Ibanez, P.2
Mena, M.A.3
-
33
-
-
77956171072
-
Impaired in vivo dopamine release in parkin knockout mice
-
Oyama G, Yoshimi K, Natori S et al. Impaired in vivo dopamine release in parkin knockout mice. Brain Res 2010;1352:214-222.
-
(2010)
Brain Res
, vol.1352
, pp. 214-222
-
-
Oyama, G.1
Yoshimi, K.2
Natori, S.3
-
34
-
-
78650752631
-
Reward, dopamine and the control of food intake: Implications for obesity
-
Volkow ND, Wang GJ, Baler RD. Reward, dopamine and the control of food intake: implications for obesity. Trends Cogn Sci (Regul Ed) 2011;15:37-46.
-
(2011)
Trends Cogn Sci (Regul Ed
, vol.15
, pp. 37-46
-
-
Volkow, N.D.1
Wang, G.J.2
Baler, R.D.3
-
35
-
-
0041422625
-
Feeding-induced dopamine release in dorsal striatum correlates with meal pleasantness ratings in healthy human volunteers
-
Small DM, Jones-Gotman M, Dagher A. Feeding-induced dopamine release in dorsal striatum correlates with meal pleasantness ratings in healthy human volunteers. Neuroimage 2003;19:1709-1715.
-
(2003)
Neuroimage
, vol.19
, pp. 1709-1715
-
-
Small, D.M.1
Jones-Gotman, M.2
Dagher, A.3
-
36
-
-
44149127949
-
Widespread reward-system activation in obese women in response to pictures of high-calorie foods
-
Stoeckel LE, Weller RE, Cook EW 3rd et al. Widespread reward-system activation in obese women in response to pictures of high-calorie foods. Neuroimage 2008;41:636-647.
-
(2008)
Neuroimage
, vol.41
, pp. 636-647
-
-
Stoeckel, L.E.1
Weller, R.E.2
Cook III, E.W.3
-
37
-
-
56849092405
-
Relation of reward from food intake and anticipated food intake to obesity: A functional magnetic resonance imaging study
-
Stice E, Spoor S, Bohon C, Veldhuizen MG, Small DM. Relation of reward from food intake and anticipated food intake to obesity: a functional magnetic resonance imaging study. J Abnorm Psychol 2008;117:924-935.
-
(2008)
J Abnorm Psychol
, vol.117
, pp. 924-935
-
-
Stice, E.1
Spoor, S.2
Bohon, C.3
Veldhuizen, M.G.4
Small, D.M.5
-
38
-
-
80052389174
-
Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells
-
Kim KY, Stevens MV, Akter MH et al. Parkin is a lipid-responsive regulator of fat uptake in mice and mutant human cells. J Clin Invest 2011;121: 3701-3712.
-
(2011)
J Clin Invest
, vol.121
, pp. 3701-3712
-
-
Kim, K.Y.1
Stevens, M.V.2
Akter, M.H.3
-
39
-
-
57149114936
-
Genetics meets metabolomics: A genome-wide association study of metabolite profiles in human serum
-
Gieger C, Geistlinger L, Altmaier E et al. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet 2008;4:e1000282.
-
(2008)
PLoS Genet
, vol.4
-
-
Gieger, C.1
Geistlinger, L.2
Altmaier, E.3
-
40
-
-
33846906872
-
Review: Molecular basis of MNS blood group variants
-
Palacajornsuk P. Review: molecular basis of MNS blood group variants. Immunohematology 2006;22:171-182.
-
(2006)
Immunohematology
, vol.22
, pp. 171-182
-
-
Palacajornsuk, P.1
-
41
-
-
0036714792
-
Zeta-sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy
-
Wheeler MT, Zarnegar S, McNally EM. Zeta-sarcoglycan, a novel component of the sarcoglycan complex, is reduced in muscular dystrophy. Hum Mol Genet 2002;11:2147-2154.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2147-2154
-
-
Wheeler, M.T.1
Zarnegar, S.2
McNally, E.M.3
|