In vitro antiplasmodial activity of selected Luo and Kuria medicinal plants

Journal of Ethnopharmacology

Volumn 144, Issue 3, 2012, Pages 779-781

  Owuor, B O ^a,b   Ochanda, J O ^b   Kokwaro, J O ^b   Cheruiyot, A C ^c   Yeda, R A ^c   Okudo, C A ^c   Akala, H M ^c  

^a CATHOLIC UNIVERSITY OF EASTERN AFRICA   (Kenya)

^b UNIVERSITY OF NAIROBI   (Kenya)

^c KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

Author keywords

Antiplasmodial activity; Medicinal plants; Traditional medicine Africa

Indexed keywords

AGERATUM CONYZOIDES EXTRACT; ALBIZIA CORIARIA EXTRACT; CHLOROQUINE; CROTON MACROSTACHYUS EXTRACT; OCIMUM GRATISSIMUM EXTRACT; OCIMUM KILIMANDSCHARICUM EXTRACT; PLANT EXTRACT; PLECTRANTHUS BARBATUS EXTRACT; TYLOSEMA FASSOGLENSE EXTRACT; UNCLASSIFIED DRUG; ZANTHOXYLUM CHALYBEUM EXTRACT;

AGERATUM CONYZOIDES; ALBIZIA; ALBIZIA CORIARIA; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CROTON; CROTON MACROSTACHYUS; ETHNIC GROUP; ETHNOBOTANY; FLUORESCENCE; FUNGAL STRAIN; IC 50; IN VITRO STUDY; KENYA; MEDICINAL PLANT; NONHUMAN; OCIMUM; OCIMUM GRATISSIMUM; OCIMUM KILIMANDSCHARICUM; PLANT LEAF; PLANT STEM; PLASMODIUM FALCIPARUM; PLECTRANTHUS; PLECTRANTHUS BARBATUS; TYLOSEMA FASSOGLENSE; ZANTHOXYLUM CHALYBEUM;

ANGIOSPERMS; ANTIMALARIALS; KENYA; MEDICINE, AFRICAN TRADITIONAL; PLANT EXTRACTS; PLANTS, MEDICINAL; PLASMODIUM FALCIPARUM;

AGERATUM CONYZOIDES; BAUHINIA FASSOGLENSIS; KURIA; OCIMUM KILIMANDSCHARICUM; PLASMODIUM FALCIPARUM; PLECTRANTHUS BARBATUS;

EID: 84870298436     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2012.09.045     Document Type: Article

References (17)

1. H.M. Akala, F.L. Eyase, A.C. Cheruiyot, A.A. Omondi, B.R. Ogutu, N.C. Waters, J.D. Johnson, M.E. Polhemus, D.C. Schnabel, and D.S. Walsh Antimalarial drug sensitivity profile of Western Kenya Plasmodium falciparum field isolates determined by a SYBR Green I in vitro assay and molecular analysis American Journal of Tropical Medicine and Hygiene 85 2011 34 41
2. E. Deharo, G. Bourdy, C. Quenevo, V. Muńoz, G. Ruiz, and M. Sauvain A search for natural bioactive compounds in Bolivia through a multidisciplinary approach. Part V. Evaluation of the antimalarial activity of plants used by the Tacana Indians Journal of Ethnopharmacology 77 2001 91 98
3. R.E. Desjardins, C.J. Canfield, J.D. Haynes, and J.D. Chulay Quantitative assessment of antimalarial activity in vitro by a semiautomated microdilution technique Antimicrobial Agents Chemotherapy 16 1979 710 718
4. H.O. Edeoga, D.E. Okwu, and B.O. Mbaebie Phytochemical constituents of some Nigerian medicinal plants African Journal of Biotechnology 4 2005 685 688
5. D.S. Fabricant, and N.R. Farnsworth The value of plants used in traditional medicine for drug discovery Environmental Health Perspectives 109 2001 69 75
6. X. Franck, A. Fournet, E. Prina, R. Mahieux, R. Hocquemiller, and B. Figadère Biological evaluation of substituted quinolines Bioorganic and Medicinal Chemistry Letters 14 2004 3635 3638
7. J.D. Johnson, R.A. Dennull, L. Gerena, M. Lopez-Sanchez, N.E. Roncal, and N.C. Waters Assessment and continued validation of the malaria SYBR Green I-based fluorescence assay for use in malaria drug screening Antimicrobial Agents Chemotherapy 51 2007 1926 1933
8. P.W. Juma, H.M. Akala, F.L. Eyase, L.M. Muiva, M. Heydenreich, F.A. Okalebo, P.M. Gitu, M.G. Peter, D. Walsh, M. Imbuga, and A. Yenesew Terpurinflavone: an antiplasmodial flavone from the stem of Tephrosia purpurea Phytochemistry Letters 4 2011 176 178
9. F.W. Muregi, S.C. Chhabra, E.N.M. Njagi, C.C. Lang'at-Thoruwa, W.M. Njue, A.S.S. Orago, S.A. Omar, and I.O. Ndiege In vitro antiplasmodial activity of some plants used in Kisii, Kenya against malaria and their chloroquine potentiation effects Journal of Ethnopharmacology 84 2003 235 239
10. A.M.M. Nour, S.A. Khalid, M. Kaiser, R. Brun, W.E. Abdalla, and T.J. Schmidt The antiprotozoal activity of methylated flavonoids from Ageratum conyzoides L Journal of Ethnopharmacology 129 2010 127 130
11. J.A. Orwa, P.G. Mwitari, E.N. Matu, and G.M. Rukunga Traditional healers and the management of malaria in Kisumu district, Kenya East Africa Medical Journal 84 2007 51 55
12. M. Ramharter, W.H. Wernsdorfer, and P.G. Kremsner In vitro activity of quinolines against Plasmodium falciparum in Gabon Acta Tropica 90 2004 55 60
13. M. Smilkstein, N. Sriwilaijaroen, J.X. Kelly, P. Wilairat, and M. Riscoe Simple and inexpensive fluorescence-based technique for highthroughput antimalarial drug screening Antimicrobial Agents Chemotherapy 48 2004 1803 1806
14. W. Trager, and J.B. Jensen Human malaria parasites in continuous culture Science 193 1976 673 675
15. V.C. Ukwe, E.A. Epueke, O.I. Ekwunife, T.C. Okoye, G.C. Akudor, and C.M. Ubaka Antimalarial activity of aqueous extract and fractions of leaves of Ageratum conyzoides in mice infected with Plasmodium berghei International Journal of Pharmaceutical Sciences 2 2010 33 38
16. M.L. Willcox, and G. Bodeker Traditional herbal medicines for malaria British Medical Journal 329 7475 2004 1156 1159
17. WHO, 2011. World Malaria Report. World Health Organization Global Malaria Programme, Geneva.